12.50138 % | RA Capital Management, LP | 18,202,009 | 1,000,000 | 12/31/2023 |
9.60423 % | GSK plc | 13,983,761 | 3,300,000 | 12/31/2023 |
5.80206 % | Maverick Capital, Ltd. | 8,447,804 | 1,853,485 | 12/31/2023 |
5.06416 % | M28 Capital Management LP | 7,373,413 | 328,913 | 12/31/2023 |
4.11245 % | Adage Capital Management, L.P. | 5,987,730 | 2,200,000 | 12/31/2023 |
3.91831 % | Shin Nippon Biomedical Laboratories Ltd | 5,705,060 | 0 | 6/12/2023 |
3.84615 % | 683 Capital Management LLC | 5,600,000 | -250,000 | 12/31/2023 |
3.36760 % | BlackRock Institutional Trust Company, N.A. | 4,903,231 | 431,425 | 12/31/2023 |
3.08685 % | Bellevue Asset Management AG | 4,494,458 | 0 | 12/31/2023 |
2.70061 % | Kynam Capital Management LP | 3,932,082 | 0 | 12/31/2023 |
2.58201 % | PRIMECAP Management Company | 3,759,408 | -21,100 | 12/31/2023 |
2.20707 % | Point72 Asset Management, L.P. | 3,213,500 | 3,213,500 | 12/31/2023 |
2.06552 % | Invus Public Equities Advisors, LLC | 3,007,400 | 1,007,400 | 12/31/2023 |
1.38728 % | Kagoshima Shinsangyo Sousei Investment, L. P. | 2,019,873 | 2,019,873 | 7/19/2022 |
1.36144 % | Citadel Advisors LLC | 1,982,252 | 1,982,252 | 12/31/2023 |
1.07788 % | T. Rowe Price Associates, Inc. | 1,569,395 | 356,463 | 12/31/2023 |
1.00259 % | Geode Capital Management, L.L.C. | 1,459,764 | 64,627 | 12/31/2023 |
0.99779 % | Maven Investment Partners US Ltd. | 1,452,778 | 1,452,778 | 12/31/2023 |
0.95574 % | Woodline Partners LP | 1,391,561 | 162,878 | 12/31/2023 |
0.89195 % | The Vanguard Group, Inc. | 1,298,677 | 116,075 | 12/31/2023 |
0.86795 % | State Street Global Advisors (US) | 1,263,729 | 68,982 | 12/31/2023 |
0.82570 % | Fidelity Management & Research Company LLC | 1,202,215 | 541,790 | 12/31/2023 |
0.73592 % | Laurion Capital Management LP | 1,071,500 | 200,000 | 12/31/2023 |
0.45009 % | Platinum Asset Management | 655,331 | 200,000 | 12/31/2023 |
0.40355 % | Driehaus Capital Management, LLC | 587,575 | 587,575 | 12/31/2023 |
0.36747 % | Northern Trust Investments, Inc. | 535,041 | 69,023 | 12/31/2023 |
0.35342 % | Millennium Management LLC | 514,581 | 259,687 | 12/31/2023 |
0.35027 % | Newtyn Management, LLC | 510,000 | 0 | 12/31/2023 |
0.34355 % | Marshall Wace LLP | 500,209 | 318,571 | 12/31/2023 |
0.29734 % | Walleye Capital LLC | 432,933 | 283,973 | 12/31/2023 |
0.27982 % | Bolno (Paul B. M.D.) | 407,425 | 0 | 6/12/2023 |
0.27579 % | JPMorgan Asset Management U.K. Limited | 401,551 | 0 | 12/31/2023 |
0.22952 % | Goldman Sachs & Company, Inc. | 334,175 | 41,655 | 12/31/2023 |
0.18825 % | Wellington Management Company, LLP | 274,093 | 9,208 | 12/31/2023 |
0.14586 % | Jacobs Levy Equity Management, Inc. | 212,377 | 212,377 | 12/31/2023 |
0.14270 % | Nuveen LLC | 207,771 | -5,067 | 12/31/2023 |
0.14131 % | TD Asset Management Inc. | 205,746 | 43,054 | 12/31/2023 |
0.13236 % | Water Street Capital, Inc. | 192,722 | 0 | 12/31/2023 |
0.12708 % | BlackRock Financial Management, Inc. | 185,031 | 28,315 | 12/31/2023 |
0.12214 % | Morgan Stanley & Co. LLC | 177,832 | 107,906 | 12/31/2023 |
0.11918 % | BlackRock Investment Management, LLC | 173,523 | -200 | 12/31/2023 |
0.11655 % | Charles Schwab Investment Management, Inc. | 169,693 | 0 | 12/31/2023 |
0.10467 % | Schweizerische Nationalbank | 152,400 | 152,400 | 12/31/2023 |
0.09826 % | BNY Mellon Asset Management | 143,067 | -1,177 | 12/31/2023 |
0.09163 % | Manulife Investment Management (North America) Limited | 133,406 | 51,087 | 12/31/2023 |
0.08443 % | Barclays Bank PLC | 122,928 | 105,401 | 12/31/2023 |
0.07871 % | Rhumbline Advisers Ltd. Partnership | 114,595 | 3,084 | 12/31/2023 |
0.07688 % | Credit Suisse Funds AG | 111,931 | 94,461 | 12/31/2023 |
0.07095 % | Monashee Investment Management, LLC | 103,300 | 103,300 | 12/31/2023 |
0.06886 % | BlackRock Advisors (UK) Limited | 100,257 | 4,241 | 3/31/2024 |
0.06617 % | Vargeese (Chandra) | 96,346 | 0 | 6/12/2023 |
0.06111 % | Balyasny Asset Management LP | 88,970 | 52,618 | 12/31/2023 |
0.05629 % | Macquarie Investment Management | 81,955 | 0 | 12/31/2023 |
0.05603 % | UBS Financial Services, Inc. | 81,584 | 56,701 | 12/31/2023 |
0.05537 % | Assenagon Asset Management S.A. | 80,624 | 5,873 | 2/29/2024 |
0.05456 % | Jane Street Capital, L.L.C. | 79,438 | 79,438 | 12/31/2023 |
0.05403 % | California State Teachers Retirement System | 78,661 | 65,614 | 12/31/2023 |
0.05331 % | a16z Perennial Management, L.P. | 77,619 | 77,619 | 12/31/2023 |
0.05206 % | State Teachers Retirement System of Ohio | 75,800 | 75,800 | 12/31/2023 |
0.04726 % | Martingale Asset Management, L.P. | 68,807 | 25,190 | 12/31/2023 |
0.04468 % | J. J. Burns & Company, LLC | 65,049 | 32,000 | 12/31/2023 |
0.04274 % | BofA Global Research (US) | 62,226 | 17,247 | 12/31/2023 |
0.04007 % | Barclays Capital Inc. | 58,339 | 58,339 | 12/31/2023 |
0.03981 % | T. Rowe Price International Ltd | 57,968 | 1,738 | 12/31/2023 |
0.03917 % | UBS Asset Management (Switzerland) | 57,026 | 50,287 | 12/31/2023 |
0.03912 % | Goldman Sachs Asset Management, L.P. | 56,957 | 7,683 | 12/31/2023 |
0.03541 % | Francis (Christopher John) | 51,564 | -10,258 | 2/16/2023 |
0.03497 % | BlackRock Asset Management Ireland Limited | 50,923 | 8,721 | 12/31/2023 |
0.03434 % | Capstone Investment Advisors, LLC | 50,000 | 50,000 | 12/31/2023 |
0.03390 % | Legal & General Investment Management Ltd. | 49,356 | 44,618 | 12/31/2023 |
0.03357 % | Northern Trust Global Investments | 48,884 | -8 | 12/31/2023 |
0.03228 % | Kraematon Investment Advisors, Inc | 47,000 | 47,000 | 12/31/2023 |
0.03091 % | ACCI Capital Investments SGIIC, SA | 45,000 | 45,000 | 12/31/2023 |
0.03045 % | UBS Asset Management (UK) Ltd. | 44,341 | 0 | 2/29/2024 |
0.02921 % | Putnam Investment Management, L.L.C. | 42,537 | 42,537 | 12/31/2023 |
0.02921 % | Northern Trust Global Investments Limited | 42,525 | 42,525 | 12/31/2023 |
0.02832 % | BNP Paribas Securities Corp. North America | 41,234 | 30,858 | 12/31/2023 |
0.02747 % | Birchview Capital, LP | 40,000 | 40,000 | 12/31/2023 |
0.02686 % | JPMorgan Private Bank (United States) | 39,111 | 39,111 | 12/31/2023 |
0.02512 % | Tudor Investment Corporation | 36,580 | 36,580 | 12/31/2023 |
0.02506 % | Mellon Investments Corporation | 36,491 | 3,981 | 12/31/2023 |
0.02440 % | Mirae Asset Global Investments (USA) LLC | 35,523 | -51,130 | 12/31/2023 |
0.02404 % | Deka Investment GmbH | 35,000 | 35,000 | 12/31/2022 |
0.02374 % | SG Americas Securities, L.L.C. | 34,562 | 8,694 | 12/31/2023 |
0.02365 % | Virtu Americas LLC | 34,432 | 34,432 | 12/31/2023 |
0.02215 % | Zürcher Kantonalbank (Asset Management) | 32,250 | 30,250 | 12/31/2023 |
0.02206 % | Trexquant Investment LP | 32,119 | 32,119 | 12/31/2023 |
0.02158 % | MetLife Investment Management, LLC | 31,423 | 0 | 12/31/2023 |
0.02153 % | Aperio Group, LLC | 31,347 | 12,028 | 12/31/2023 |
0.02060 % | Verdine Gregory L | 30,000 | 0 | 6/12/2023 |
0.02019 % | SunAmerica Asset Management, LLC | 29,390 | -119 | 12/31/2023 |
0.01992 % | SEI Investments Management Corporation | 29,000 | 0 | 12/31/2023 |
0.01986 % | Invesco Advisers, Inc. | 28,919 | 7,151 | 12/31/2023 |
0.01886 % | DWS Investments UK Limited | 27,457 | -714 | 12/31/2023 |
0.01842 % | Engineers Gate Manager, L.P. | 26,820 | 26,820 | 12/31/2023 |
0.01823 % | Two Sigma Investments, LP | 26,543 | 26,543 | 12/31/2023 |
0.01786 % | Columbia Threadneedle Investments (US) | 25,999 | 25,999 | 12/31/2023 |
0.01785 % | Conestoga Capital Advisors, LLC | 25,994 | 0 | 2/29/2024 |
0.01731 % | Vaughan Nelson Investment Management, L.P. | 25,203 | 0 | 12/31/2023 |
0.01717 % | Cinctive Capital Management LP | 25,000 | 25,000 | 12/31/2023 |