14.78397 % | Frazier Life Sciences Management, L.P. | 10,109,280 | 1 | 8/20/2024 |
10.91631 % | Medicxi Ventures (UK) LLP | 7,464,572 | 0 | 9/30/2024 |
5.11379 % | Abingworth Management Limited | 3,496,808 | 0 | 6/30/2024 |
4.20334 % | Invesco Advisers, Inc. | 2,874,243 | -13,019 | 6/30/2024 |
4.08084 % | Takeda Pharmaceutical Co Ltd | 2,790,480 | -362,737 | 4/9/2024 |
4.03273 % | Jennison Associates LLC | 2,757,579 | 1,109,882 | 6/30/2024 |
3.74111 % | BlackRock Institutional Trust Company, N.A. | 2,558,174 | 151,552 | 6/30/2024 |
3.28287 % | Ensign Peak Advisors, Inc. | 2,244,828 | -35,172 | 6/30/2024 |
3.22495 % | The Vanguard Group, Inc. | 2,205,222 | 232,642 | 6/30/2024 |
2.86658 % | New Enterprise Associates (NEA) | 1,960,169 | 0 | 6/30/2024 |
2.36911 % | Avidity Partners Management LP | 1,620,000 | -115,000 | 6/30/2024 |
2.15305 % | Gilder Gagnon Howe & Co. LLC | 1,472,259 | 454,642 | 6/30/2024 |
2.04738 % | 683 Capital Management LLC | 1,400,000 | -250,000 | 6/30/2024 |
1.80061 % | Socks (David A) | 1,231,256 | 10,500 | 5/23/2024 |
1.65266 % | Portolan Capital Management, L.L.C. | 1,130,089 | 1,130,089 | 6/30/2024 |
1.29160 % | Nabulsi (Azmi) | 883,199 | -10,901 | 7/15/2024 |
1.27961 % | Checkpoint Capital L.P. | 875,000 | 429,839 | 6/30/2024 |
1.27220 % | Propel Bio Management, LLC | 869,927 | 0 | 6/30/2024 |
1.24305 % | Decheng Capital LLC | 850,000 | 0 | 6/30/2024 |
1.21513 % | Kennedy Capital Management LLC | 830,906 | 258,570 | 6/30/2024 |
1.17878 % | Geode Capital Management, L.L.C. | 806,047 | 54,668 | 6/30/2024 |
1.14944 % | Woodline Partners LP | 785,990 | 219,551 | 6/30/2024 |
1.14836 % | State Street Global Advisors (US) | 785,249 | 68,048 | 6/30/2024 |
1.06566 % | Morgan Stanley & Co. LLC | 728,700 | 519,176 | 6/30/2024 |
1.05581 % | Catalys Pacific, LLC | 721,962 | 0 | 6/30/2024 |
0.87810 % | GW&K Investment Management, LLC | 600,443 | 32,417 | 6/30/2024 |
0.87745 % | Ghost Tree Capital, LLC | 600,000 | 115,000 | 6/30/2024 |
0.86766 % | Saturn V Capital Management LP | 593,306 | 92,319 | 6/30/2024 |
0.80485 % | Medical Strategy GmbH | 550,354 | -28,000 | 6/30/2024 |
0.76329 % | Simplify Asset Management Inc | 521,935 | 0 | 6/30/2024 |
0.61726 % | StepStone Group LP | 422,085 | 0 | 6/30/2024 |
0.52861 % | Eagle Asset Management, Inc. | 361,463 | 56,624 | 6/30/2024 |
0.51185 % | PGIM Securities Investment Trust Enterprise | 350,000 | 350,000 | 6/30/2024 |
0.46758 % | Two Sigma Investments, LP | 319,731 | -199,317 | 6/30/2024 |
0.45316 % | Goldman Sachs & Company, Inc. | 309,874 | 150,653 | 6/30/2024 |
0.41806 % | Charles Schwab Investment Management, Inc. | 285,870 | 21,376 | 6/30/2024 |
0.39046 % | Invesco Canada Ltd. | 266,994 | -3,638 | 6/30/2024 |
0.36850 % | Northern Trust Investments, Inc. | 251,983 | -6,399 | 6/30/2024 |
0.33144 % | Wellington Management Company, LLP | 226,641 | 3,251 | 6/30/2024 |
0.32904 % | Oracle Investment Management, Inc. | 225,000 | 225,000 | 6/30/2024 |
0.24616 % | Schonfeld Strategic Advisors LLC | 168,323 | 23,623 | 6/30/2024 |
0.20360 % | Nuveen LLC | 139,222 | -121,026 | 6/30/2024 |
0.18701 % | Arctic Fund Management AS | 127,878 | 63,900 | 4/30/2024 |
0.17549 % | Moore Capital Management, LP | 120,000 | 0 | 6/30/2024 |
0.16935 % | BlackRock Advisors (UK) Limited | 115,802 | 6,288 | 9/30/2024 |
0.16612 % | State of Wisconsin Investment Board | 113,592 | 54,406 | 6/30/2024 |
0.16532 % | JP Morgan Asset Management | 113,044 | 0 | 6/30/2024 |
0.16480 % | Marshall Wace LLP | 112,691 | 112,691 | 6/30/2024 |
0.15708 % | Goldman Sachs Asset Management, L.P. | 107,410 | 59,259 | 6/30/2024 |
0.14920 % | Curran (Terrie) | 102,026 | -33,848 | 7/15/2024 |
0.14796 % | BlackRock Financial Management, Inc. | 101,178 | 8,173 | 6/30/2024 |
0.14765 % | BlackRock Investment Management, LLC | 100,960 | 15,788 | 6/30/2024 |
0.14336 % | BofA Global Research (US) | 98,032 | -7,823 | 6/30/2024 |
0.13727 % | SEI Investments Management Corporation | 93,863 | 77,372 | 9/30/2024 |
0.12645 % | BlackRock Asset Management Ireland Limited | 86,468 | -1,840 | 6/30/2024 |
0.12392 % | Azimut Capital Management Sgr SpA | 84,738 | -979 | 9/30/2024 |
0.11699 % | Advisory Invest GmbH | 80,000 | -68,079 | 8/31/2024 |
0.11526 % | Citadel Advisors LLC | 78,816 | -46,829 | 6/30/2024 |
0.11518 % | BNY Mellon Asset Management | 78,757 | 8,662 | 6/30/2024 |
0.09579 % | Parikh (Asit) | 65,500 | 10,500 | 5/23/2024 |
0.09184 % | Penn Mutual Asset Management, LLC | 62,802 | 0 | 6/30/2024 |
0.08190 % | Schweizerische Nationalbank | 56,000 | 0 | 6/30/2024 |
0.08167 % | Jane Street Capital, L.L.C. | 55,848 | 30,827 | 6/30/2024 |
0.08106 % | UBS Asset Management (Switzerland) | 55,427 | 42,534 | 6/30/2024 |
0.08069 % | Rhumbline Advisers Ltd. Partnership | 55,178 | 8,075 | 6/30/2024 |
0.07328 % | AllianceBernstein L.P. | 50,110 | 17,820 | 6/30/2024 |
0.06827 % | Henderson (Molly) | 46,682 | -4,325 | 7/15/2024 |
0.06508 % | Karbe (Frank L) | 44,500 | 35,500 | 5/29/2024 |
0.06301 % | UBS Financial Services, Inc. | 43,086 | -6,837 | 6/30/2024 |
0.05905 % | Dimensional Fund Advisors, L.P. | 40,381 | 14,900 | 8/31/2024 |
0.05378 % | Legal & General Investment Management Ltd. | 36,773 | 2,671 | 6/30/2024 |
0.05357 % | Inspirion Wealth Advisors, LLC | 36,634 | 0 | 9/30/2024 |
0.05259 % | Mellon Investments Corporation | 35,964 | 10,838 | 6/30/2024 |
0.04866 % | BlackRock Asset Management Canada Limited | 33,271 | -2,862 | 6/30/2024 |
0.04399 % | Virtus Etf Advisers LLC | 30,078 | 20,377 | 6/30/2024 |
0.04339 % | Occidental Asset Management, LLC | 29,672 | 0 | 9/30/2024 |
0.04300 % | GSA Capital Partners LLP | 29,406 | 15,232 | 6/30/2024 |
0.04285 % | Cola (Michael F) | 29,298 | 10,500 | 5/23/2024 |
0.04248 % | California State Teachers Retirement System | 29,051 | 104 | 6/30/2024 |
0.03980 % | Aperio Group, LLC | 27,213 | 10,182 | 6/30/2024 |
0.03941 % | Creative Planning, Inc. | 26,951 | -5,151 | 6/30/2024 |
0.03749 % | Assenagon Asset Management S.A. | 25,633 | 3,200 | 9/30/2024 |
0.03730 % | Topper (James N) | 25,508 | 0 | 8/20/2024 |
0.03388 % | UBS Fund Management (Switzerland) AG | 23,164 | -16,519 | 6/30/2024 |
0.03304 % | Allworth Financial, L.P. | 22,594 | 14 | 9/30/2024 |
0.03009 % | T. Rowe Price International Ltd | 20,575 | 1,002 | 6/30/2024 |
0.02866 % | MML Investors Services, LLC | 19,600 | 19,600 | 6/30/2024 |
0.02865 % | Northern Trust Global Investments | 19,588 | 102 | 6/30/2024 |
0.02852 % | Stenhouse (Mark) | 19,500 | 10,500 | 5/23/2024 |
0.02852 % | Fields-Kunz (Heidi) | 19,500 | 10,500 | 5/23/2024 |
0.02755 % | Parametric Portfolio Associates LLC | 18,840 | 4,590 | 6/30/2024 |
0.02748 % | Brevan Howard Capital Management LP | 18,792 | 18,792 | 6/30/2024 |
0.02685 % | Corebridge Financial Inc | 18,358 | 18,358 | 6/30/2024 |
0.02675 % | MetLife Investment Management, LLC | 18,289 | 1,818 | 6/30/2024 |
0.02635 % | Mirae Asset Global Investments (USA) LLC | 18,018 | 4,112 | 6/30/2024 |
0.02393 % | BlackRock Investment Management (UK) Ltd. | 16,360 | 0 | 6/30/2024 |
0.02311 % | SunAmerica Asset Management, LLC | 15,802 | -136 | 3/31/2024 |
0.02238 % | Apo Asset Management GmbH | 15,301 | 0 | 3/31/2024 |
0.02202 % | DWS Investments UK Limited | 15,058 | 872 | 6/30/2024 |
0.02195 % | Balyasny Asset Management LP | 15,006 | 15,006 | 6/30/2024 |