16.61932 % | Redmile Group, LLC | 16,069,217 | 800,000 | 7/1/2024 |
10.12405 % | HPWH TH AG | 9,788,944 | 0 | 9/1/2024 |
9.89761 % | Prosight Capital | 9,570,000 | 2,519,700 | 6/30/2024 |
4.46460 % | OrbiMed Advisors, LLC | 4,316,824 | 4,316,824 | 6/30/2024 |
4.15453 % | Oaktree Capital Management, L.P. | 4,017,013 | 4,017,013 | 4/25/2024 |
4.14853 % | AstraZeneca (UK) Ltd. | 4,011,215 | 0 | 12/31/2023 |
3.30553 % | BlackRock Institutional Trust Company, N.A. | 3,196,115 | 3,196,115 | 6/30/2024 |
3.02400 % | Morgan Stanley & Co. LLC | 2,923,902 | 231,448 | 6/30/2024 |
2.30759 % | Auven Therapeutics General LP | 2,231,210 | -4,099,338 | 4/23/2024 |
1.82932 % | SilverArc Capital Management, LLC | 1,768,770 | 1,267,548 | 6/30/2024 |
1.59790 % | Squarer (Ron R) | 1,545,007 | -26,430 | 9/1/2024 |
1.57691 % | Goldman Sachs & Company, Inc. | 1,524,717 | -15,792 | 6/30/2024 |
1.34052 % | Platinum Asset Management | 1,296,153 | 384,755 | 6/30/2024 |
1.25806 % | BofA Global Research (US) | 1,216,418 | 22,571 | 6/30/2024 |
1.05333 % | Invus Public Equities Advisors, LLC | 1,018,461 | 1,018,461 | 6/30/2024 |
1.02580 % | Mallik (Ameet) | 991,845 | 176,350 | 9/1/2024 |
1.02523 % | State Street Global Advisors (US) | 991,296 | 991,296 | 6/30/2024 |
0.87986 % | Vantage Consulting Group, Inc. | 850,737 | 0 | 6/30/2024 |
0.85295 % | Geode Capital Management, L.L.C. | 824,717 | 824,717 | 6/30/2024 |
0.84441 % | Millennium Management LLC | 816,456 | -193,981 | 6/30/2024 |
0.75868 % | Blue Owl Capital Holdings LP | 733,568 | 0 | 6/30/2024 |
0.70902 % | Sphera Funds Management Ltd. | 685,547 | 685,547 | 6/30/2024 |
0.64718 % | Pfisterer (Thomas) | 625,756 | -20,000 | 9/1/2024 |
0.49100 % | Affinity Asset Advisors LLC | 474,744 | 474,744 | 6/30/2024 |
0.48609 % | Abaris Investment Management AG | 470,000 | 462,000 | 12/31/2023 |
0.42495 % | GCM Grosvenor Holdings, LLC | 410,888 | 0 | 6/30/2024 |
0.41807 % | The Vanguard Group, Inc. | 404,229 | 404,229 | 6/30/2024 |
0.37733 % | Two Sigma Investments, LP | 364,840 | 309,927 | 6/30/2024 |
0.33332 % | Atom Investors LP | 322,289 | 322,289 | 6/30/2024 |
0.27274 % | D. E. Shaw & Co., L.P. | 263,712 | 236,791 | 6/30/2024 |
0.24543 % | Nuveen LLC | 237,304 | 237,304 | 6/30/2024 |
0.24132 % | Zaki (Mohamed) | 233,333 | 0 | 9/1/2024 |
0.23787 % | Graham (Peter J) | 230,000 | 230,000 | 1/2/2024 |
0.23591 % | Sectoral Asset Management Inc. | 228,102 | -248,088 | 6/30/2024 |
0.21805 % | Carmona (Jose) | 210,833 | 47,916 | 9/1/2024 |
0.21107 % | Dafna Capital Management, LLC | 204,081 | 204,081 | 6/30/2024 |
0.20119 % | BlackRock Investment Management, LLC | 194,532 | 194,532 | 6/30/2024 |
0.18147 % | Charles Schwab Investment Management, Inc. | 175,462 | 175,462 | 6/30/2024 |
0.16971 % | BlackRock Financial Management, Inc. | 164,095 | 164,095 | 6/30/2024 |
0.15537 % | BNY Mellon Asset Management | 150,228 | 150,228 | 6/30/2024 |
0.14753 % | Hug (Peter) | 142,644 | -20,000 | 9/1/2024 |
0.11687 % | The Sanibel Captiva Trust Company | 113,000 | 0 | 9/30/2024 |
0.09803 % | Monges (Viviane) | 94,783 | -16,777 | 9/1/2024 |
0.08892 % | Rhumbline Advisers Ltd. Partnership | 85,977 | 85,977 | 6/30/2024 |
0.07446 % | Sandor (Victor) | 71,998 | -20,000 | 9/1/2024 |
0.05885 % | Bizzari (Jean-Pierre) | 56,904 | -16,777 | 9/1/2024 |
0.05881 % | XTX Markets LLC | 56,863 | 32,034 | 6/30/2024 |
0.05767 % | Magnetar Capital Partners LP | 55,762 | 0 | 6/30/2024 |
0.05688 % | Mellon Investments Corporation | 54,993 | 54,993 | 6/30/2024 |
0.05598 % | Susquehanna International Group, LLP | 54,126 | 54,126 | 6/30/2024 |
0.04395 % | Kallebo (Lisa Michelle) | 42,500 | 42,500 | 1/2/2024 |
0.04285 % | Citadel Advisors LLC | 41,433 | -911,031 | 6/30/2024 |
0.04180 % | Commonwealth Financial Network | 40,413 | 7,813 | 9/30/2024 |
0.03997 % | DWS Investments UK Limited | 38,649 | 38,649 | 6/30/2024 |
0.03958 % | Mirae Asset Global Investments (USA) LLC | 38,274 | -1,268 | 9/30/2024 |
0.03896 % | SunAmerica Asset Management, LLC | 37,666 | 0 | 7/31/2024 |
0.03896 % | Corebridge Financial Inc | 37,666 | 37,666 | 6/30/2024 |
0.03650 % | Goldman Sachs Asset Management, L.P. | 35,295 | -241 | 9/30/2024 |
0.03501 % | Barclays Bank PLC | 33,849 | 33,849 | 6/30/2024 |
0.03429 % | DLK Investment Management, LLC | 33,155 | 0 | 9/30/2024 |
0.03372 % | Morgan Stanley Smith Barney LLC | 32,608 | 4,683 | 6/30/2024 |
0.03275 % | Invesco Advisers, Inc. | 31,663 | 31,663 | 6/30/2024 |
0.03086 % | JPMorgan Private Bank (United States) | 29,837 | 29,837 | 6/30/2024 |
0.02786 % | Manulife Investment Management (North America) Limited | 26,938 | 26,938 | 6/30/2024 |
0.02757 % | SG Americas Securities, L.L.C. | 26,657 | 26,657 | 9/30/2024 |
0.02658 % | Wells Fargo Bank, N.A. | 25,704 | 25,704 | 6/30/2024 |
0.02535 % | Evans-Freke Stephen R | 24,509 | -40 | 4/23/2024 |
0.02511 % | Metropolitan Life Insurance Co. (US) | 24,279 | 24,279 | 6/30/2024 |
0.02495 % | Voya Investment Management LLC | 24,120 | 24,120 | 6/30/2024 |
0.02414 % | Azelby (Robert W) | 23,338 | -29,667 | 9/1/2024 |
0.02377 % | Northern Trust Investments, Inc. | 22,982 | 22,982 | 6/30/2024 |
0.02325 % | T. Rowe Price International Ltd | 22,476 | 22,476 | 6/30/2024 |
0.02300 % | Saxony Capital Management, LLC | 22,238 | 0 | 9/30/2024 |
0.02277 % | AllianceBernstein L.P. | 22,020 | 22,020 | 6/30/2024 |
0.02192 % | UBS Financial Services, Inc. | 21,193 | 21,142 | 6/30/2024 |
0.01945 % | MetLife Investment Management, LLC | 18,810 | 18,810 | 6/30/2024 |
0.01702 % | Acadian Asset Management LLC | 16,454 | 16,454 | 6/30/2024 |
0.01647 % | Caption Management, LLC | 15,925 | 15,925 | 6/30/2024 |
0.01595 % | Citi Investment Research (US) | 15,423 | 15,423 | 6/30/2024 |
0.01554 % | ProShare Advisors LLC | 15,021 | 1,564 | 9/30/2024 |
0.01476 % | Jane Street Capital, L.L.C. | 14,267 | -12,717 | 6/30/2024 |
0.01372 % | Palumbo Wealth Management LLC | 13,270 | 13,270 | 6/30/2024 |
0.01124 % | Osaic Holdings, Inc. | 10,872 | 2,872 | 6/30/2024 |
0.01071 % | Susquehanna Fundamental Investments, LLC | 10,355 | 10,355 | 6/30/2024 |
0.01070 % | Aviso Wealth Management | 10,343 | -125 | 6/30/2024 |
0.01034 % | Nomura Securities Co., Ltd. | 10,000 | 10,000 | 6/30/2024 |
0.00941 % | New York State Common Retirement Fund | 9,100 | -26,500 | 9/30/2024 |
0.00900 % | Parametric Portfolio Associates LLC | 8,703 | 8,703 | 6/30/2024 |
0.00733 % | Legal & General Investment Management Ltd. | 7,085 | 7,085 | 6/30/2024 |
0.00709 % | Ameritas Investment Partners, Inc. | 6,859 | 6,859 | 6/30/2024 |
0.00690 % | Principal Global Investors (Equity) | 6,667 | -771 | 9/30/2024 |
0.00681 % | RBC Wealth Management, International | 6,585 | 6,585 | 6/30/2024 |
0.00643 % | State of Wyoming | 6,221 | 6,221 | 6/30/2024 |
0.00549 % | Corr (Peter B) | 5,309 | 5,309 | 4/23/2024 |
0.00525 % | California State Teachers Retirement System | 5,073 | 5,073 | 6/30/2024 |
0.00511 % | Assenagon Asset Management S.A. | 4,945 | 1,237 | 8/31/2024 |
0.00427 % | Horizon Kinetics LLC | 4,129 | 0 | 8/31/2024 |
0.00307 % | Franklin Mutual Advisers, LLC | 2,966 | 0 | 8/31/2024 |
0.00295 % | RBC Capital Markets Wealth Management | 2,854 | -176 | 6/30/2024 |
0.00250 % | Amalgamated Bank Institutional Asset Management & Custody | 2,422 | 2,422 | 6/30/2024 |