9,39518 % | RA Capital Management, LP | 7.632.646 | 1.314.656 | 30.6.2024 |
6,87439 % | New Enterprise Associates (NEA) | 5.584.753 | 0 | 2.8.2024 |
5,68457 % | Perceptive Advisors LLC | 4.618.145 | 2.184.420 | 17.7.2024 |
5,06715 % | Deep Track Capital LP | 4.116.549 | 116.549 | 12.7.2024 |
4,36947 % | Vivo Capital, LLC | 3.549.758 | -60.419 | 30.6.2024 |
4,07970 % | Frazier Life Sciences Management, L.P. | 3.314.349 | 300.000 | 30.6.2024 |
3,80700 % | Maverick Capital, Ltd. | 3.092.807 | 1.316.998 | 30.6.2024 |
3,52265 % | OrbiMed Advisors, LLC | 2.861.801 | -536.266 | 30.6.2024 |
3,02499 % | Abingworth Management Limited | 2.457.500 | 0 | 30.6.2024 |
2,66322 % | Federated Hermes Global Investment Management Corp. | 2.163.600 | -95.000 | 30.6.2024 |
2,33284 % | Octagon Capital Advisors LP | 1.895.200 | -473.800 | 30.6.2024 |
2,26952 % | Caligan Partners, LP | 1.843.756 | 547.309 | 30.6.2024 |
1,93422 % | Wellington Management Company, LLP | 1.571.360 | -2.338.106 | 30.6.2024 |
1,39615 % | Bellevue Asset Management AG | 1.134.229 | -5.066 | 30.6.2024 |
1,38852 % | Jennison Associates LLC | 1.128.032 | -465.801 | 30.6.2024 |
1,37291 % | Aisling Capital Management LP | 1.115.352 | 0 | 30.6.2024 |
1,34422 % | Janus Henderson Investors | 1.092.042 | -939.952 | 30.6.2024 |
1,30780 % | Hood River Capital Management LLC | 1.062.456 | 74.700 | 30.6.2024 |
1,29350 % | Laurion Capital Management LP | 1.050.842 | 168.802 | 30.6.2024 |
1,21255 % | Rice Hall James & Associates, LLC | 985.076 | 45.500 | 30.9.2024 |
1,16861 % | T. Rowe Price Associates, Inc. | 949.375 | 946.195 | 30.6.2024 |
1,08080 % | American Century Investment Management, Inc. | 878.043 | 317.184 | 30.6.2024 |
1,05293 % | Boothbay Fund Management, LLC | 855.398 | 216.280 | 30.6.2024 |
1,02486 % | Zaccardelli (David S) | 832.593 | -658.968 | 25.10.2024 |
0,97529 % | SEB Investment Management AB | 792.325 | -155 | 30.9.2024 |
0,95150 % | Candriam Belgium S.A. | 772.997 | 772.997 | 30.6.2024 |
0,95150 % | Candriam Luxembourg S.A. | 772.997 | 0 | 30.9.2024 |
0,94947 % | Morgan Stanley & Co. LLC | 771.346 | 445.689 | 30.6.2024 |
0,88760 % | Paradigm BioCapital Advisors LP | 721.087 | 721.087 | 30.6.2024 |
0,88588 % | Fidelity Management & Research Company LLC | 719.691 | -176.319 | 30.6.2024 |
0,86164 % | Affinity Asset Advisors LLC | 700.000 | -117.833 | 30.6.2024 |
0,80450 % | Loomis, Sayles & Company, L.P. | 653.579 | 0 | 31.8.2024 |
0,77933 % | Hahn (Mark W) | 633.124 | -144.560 | 25.10.2024 |
0,73288 % | Parkman Healthcare Partners LLC | 595.389 | 65.869 | 30.6.2024 |
0,70984 % | BofA Global Research (US) | 576.677 | 467.224 | 30.6.2024 |
0,64966 % | Eventide Asset Management, LLC | 527.781 | -1.659.739 | 30.6.2024 |
0,64948 % | Millennium Management LLC | 527.640 | 23.567 | 30.6.2024 |
0,61694 % | Woodline Partners LP | 501.198 | -338.569 | 30.6.2024 |
0,60438 % | Medical Strategy GmbH | 490.998 | -22.455 | 30.6.2024 |
0,54623 % | Putnam Investment Management, L.L.C. | 443.755 | 443.755 | 31.8.2024 |
0,49953 % | ClearBridge Investments, LLC | 405.819 | 150.210 | 30.6.2024 |
0,48144 % | BlackRock Institutional Trust Company, N.A. | 391.125 | 46.284 | 30.6.2024 |
0,47293 % | Legal & General Investment Management Ltd. | 384.208 | 304.635 | 30.6.2024 |
0,42774 % | Samsara BioCapital, LLC | 347.500 | 0 | 30.6.2024 |
0,41548 % | Kennedy Capital Management LLC | 337.535 | 214.320 | 30.6.2024 |
0,37498 % | SilverArc Capital Management, LLC | 304.633 | 167.919 | 30.6.2024 |
0,31112 % | Moody Aldrich Partners, LLC | 252.752 | -43.193 | 30.9.2024 |
0,30773 % | Rosalind Advisors, Inc. | 250.000 | 0 | 30.6.2024 |
0,27326 % | Schonfeld Strategic Advisors LLC | 221.996 | -38.204 | 30.6.2024 |
0,26219 % | Alerce Investment Management, L.P. | 213.000 | 213.000 | 30.6.2024 |
0,24988 % | Knott Partners Management, LLC | 203.000 | 88.000 | 30.6.2024 |
0,24756 % | Ikarian Capital LLC | 201.116 | -174.194 | 30.6.2024 |
0,24618 % | Knoll Capital Management, LLC | 200.000 | 0 | 30.6.2024 |
0,21738 % | PGIM Securities Investment Trust Enterprise | 176.600 | 0 | 30.6.2024 |
0,21541 % | Adage Capital Management, L.P. | 175.000 | 0 | 30.6.2024 |
0,20733 % | Jump Financial, LLC | 168.438 | 153.709 | 30.6.2024 |
0,20144 % | 1492 Capital Management, LLC | 163.647 | -616 | 30.6.2024 |
0,19182 % | Hennion & Walsh Asset Management, Inc. | 155.835 | 20.206 | 30.9.2024 |
0,17417 % | Neuberger Berman, LLC | 141.494 | -72.737 | 30.6.2024 |
0,16099 % | Artia Global Partners LP | 130.790 | 0 | 30.6.2024 |
0,15580 % | Goldman Sachs & Company, Inc. | 126.573 | 33.793 | 30.6.2024 |
0,14968 % | TD Asset Management Inc. | 121.600 | 121.600 | 30.6.2024 |
0,14451 % | Susquehanna International Group, LLP | 117.397 | 117.397 | 30.6.2024 |
0,12996 % | Ebsworth (David R) | 105.580 | -140.000 | 1.3.2024 |
0,12631 % | Citadel Advisors LLC | 102.615 | -39.597 | 30.6.2024 |
0,12309 % | UBS Switzerland AG | 100.000 | 100.000 | 30.6.2024 |
0,11995 % | Rickard (Kathleen A) | 97.445 | 5.864 | 7.8.2024 |
0,11560 % | Wellington Management Singapore Pte. Ltd. | 93.917 | 93.917 | 31.3.2024 |
0,11560 % | Wellington Management Japan Pte Ltd | 93.917 | -77.772 | 30.6.2023 |
0,10371 % | Morgan Stanley Smith Barney LLC | 84.252 | 82.757 | 30.6.2024 |
0,09949 % | Wells Fargo Advisors | 80.822 | 20.631 | 30.6.2024 |
0,09170 % | Allianz Global Investors GmbH | 74.495 | 15.540 | 31.8.2024 |
0,08220 % | SEI Investments Management Corporation | 66.781 | -7.513 | 30.6.2024 |
0,08167 % | AMI Asset Management Corp. | 66.346 | -3.654 | 30.9.2024 |
0,08117 % | Geode Capital Management, L.L.C. | 65.944 | 572 | 30.6.2024 |
0,07784 % | Alps Advisors, Inc. | 63.238 | 6.236 | 30.6.2024 |
0,07698 % | Invesco Advisers, Inc. | 62.541 | -1.308 | 31.7.2024 |
0,07314 % | Manulife Investment Management (North America) Limited | 59.418 | 59.418 | 30.6.2024 |
0,06893 % | LifeSci Fund Management LLC | 56.000 | 0 | 30.6.2024 |
0,06401 % | Azimut Capital Management Sgr SpA | 51.998 | -881 | 30.9.2024 |
0,06376 % | BIT Capital GmbH | 51.802 | 51.802 | 31.12.2023 |
0,06184 % | Jane Street Capital, L.L.C. | 50.239 | 12.127 | 30.6.2024 |
0,06155 % | AlphaCentric Advisors LLC. | 50.000 | -6.000 | 30.9.2024 |
0,06155 % | Resolute Capital Asset Partners LLC | 50.000 | 50.000 | 30.6.2024 |
0,06155 % | Taikang Asset Management (Hong Kong) Co., Ltd. | 50.000 | 50.000 | 30.6.2024 |
0,06127 % | First Trust Advisors L.P. | 49.775 | 120 | 30.9.2024 |
0,05327 % | California State Teachers Retirement System | 43.280 | 43.280 | 30.6.2023 |
0,05152 % | Ullman (Anders M.D., Ph.D.) | 41.857 | 0 | 1.3.2024 |
0,05055 % | BlackRock Advisors (UK) Limited | 41.065 | 2.152 | 30.9.2024 |
0,04763 % | BlackRock Asset Management Ireland Limited | 38.694 | 2.997 | 30.6.2024 |
0,04530 % | PFG Investments, LLC | 36.800 | -7.800 | 30.9.2024 |
0,04308 % | CM Management, LLC | 35.000 | 0 | 30.6.2024 |
0,04286 % | Glenmede Investment Management LP | 34.816 | 370 | 30.6.2024 |
0,04132 % | State Street Global Advisors (US) | 33.572 | 0 | 30.6.2024 |
0,03994 % | HighVista Strategies LLC | 32.449 | 0 | 30.6.2024 |
0,03976 % | Managed Account Advisors LLC | 32.303 | 14.645 | 30.6.2024 |
0,03821 % | Renaissance Technologies LLC | 31.044 | 31.044 | 30.6.2024 |
0,03519 % | Envestnet Asset Management, Inc. | 28.591 | 896 | 30.6.2024 |
0,03021 % | Assenagon Asset Management S.A. | 24.541 | 698 | 30.9.2024 |
0,02880 % | Matisse Capital | 23.400 | -11.000 | 30.9.2024 |