9,26521 % | Wellington Management Company, LLP | 7.376.961 | -519.671 | 31.12.2024 |
8,61570 % | RTW Investments L.P. | 6.859.823 | 940.388 | 31.12.2024 |
7,57880 % | Janus Henderson Investors | 6.034.239 | -1.043.239 | 31.12.2024 |
6,57371 % | General Atlantic LLC | 5.233.989 | 0 | 31.12.2024 |
6,45011 % | BlackRock Institutional Trust Company, N.A. | 5.135.581 | 130.575 | 31.12.2024 |
5,32778 % | T. Rowe Price Associates, Inc. | 4.241.976 | 531.869 | 31.12.2024 |
4,63862 % | The Vanguard Group, Inc. | 3.693.268 | 27.830 | 31.12.2024 |
2,93387 % | State Street Global Advisors (US) | 2.335.944 | -167.002 | 31.12.2024 |
2,31007 % | AllianceBernstein L.P. | 1.839.281 | -177.807 | 31.12.2024 |
1,95884 % | Geode Capital Management, L.L.C. | 1.559.631 | -11.381 | 31.12.2024 |
1,87139 % | Deep Track Capital LP | 1.490.000 | 800.216 | 31.12.2024 |
1,85458 % | Alkeon Capital Management LLC | 1.476.618 | -1.314.819 | 31.12.2024 |
1,70170 % | Citadel Advisors LLC | 1.354.893 | 1.204.992 | 31.12.2024 |
1,55138 % | Redmile Group, LLC | 1.235.209 | -152.270 | 31.12.2024 |
1,48906 % | Perceptive Advisors LLC | 1.185.592 | -529.214 | 31.12.2024 |
1,37790 % | Baker Bros. Advisors LP | 1.097.082 | 0 | 31.12.2024 |
1,18877 % | Rock Springs Capital Management LP | 946.499 | 13.100 | 31.12.2024 |
1,12997 % | Point72 Asset Management, L.P. | 899.680 | -403.643 | 31.12.2024 |
1,09557 % | Emerald Advisers LLC | 872.294 | -67.334 | 31.12.2024 |
1,00477 % | Logos Global Management LLC | 800.000 | 0 | 31.12.2024 |
0,92887 % | SilverArc Capital Management, LLC | 739.563 | 99.723 | 31.12.2024 |
0,90380 % | Long Focus Capital Management LLC | 719.604 | 0 | 31.12.2024 |
0,84156 % | T. Rowe Price Investment Management, Inc. | 670.048 | -630.048 | 31.12.2024 |
0,83666 % | Yiheng Capital Management, L.P. | 666.145 | -92.624 | 31.12.2024 |
0,81529 % | Balyasny Asset Management LP | 649.134 | 649.134 | 31.12.2024 |
0,75106 % | SG Americas Securities, L.L.C. | 597.993 | 583.486 | 31.12.2024 |
0,72592 % | Northern Trust Investments, Inc. | 577.980 | 51.553 | 31.12.2024 |
0,70664 % | Pfizer Inc | 562.626 | -1.962.626 | 31.12.2024 |
0,70149 % | Cheng (Andrew) | 558.529 | -30.000 | 10.2.2025 |
0,67909 % | Charles Schwab Investment Management, Inc. | 540.692 | 8.096 | 31.12.2024 |
0,57852 % | MPM BioImpact LLC | 460.617 | 68.073 | 31.12.2024 |
0,56407 % | Dimensional Fund Advisors, L.P. | 449.110 | 442.014 | 31.12.2024 |
0,51574 % | University of Wisconsin Foundation | 410.630 | -13.219 | 31.12.2024 |
0,50251 % | BlackRock Financial Management, Inc. | 400.097 | 39.429 | 31.12.2024 |
0,47723 % | Woodline Partners LP | 379.967 | 87.499 | 31.12.2024 |
0,47017 % | Goldman Sachs & Company, Inc. | 374.351 | -167.096 | 31.12.2024 |
0,46702 % | UBS Financial Services, Inc. | 371.844 | 281.617 | 31.12.2024 |
0,45859 % | Morgan Stanley & Co. LLC | 365.130 | -18.429 | 31.12.2024 |
0,45843 % | Foresite Capital Management VI LLC(Sibling) | 365.000 | 365.000 | 31.12.2024 |
0,45843 % | Foresite Capital Management, LLC | 365.000 | 365.000 | 31.12.2024 |
0,43171 % | Propel Bio Management, LLC | 343.729 | 0 | 31.12.2024 |
0,43117 % | JP Morgan Asset Management | 343.299 | -76.230 | 31.12.2024 |
0,35751 % | Oppenheimer Asset Management Inc. | 284.650 | -248.917 | 31.12.2024 |
0,35715 % | Harrison (Seth Loring) | 284.364 | 0 | 2.4.2024 |
0,34665 % | Rheos Capital Works Inc. | 276.000 | 0 | 31.12.2024 |
0,34548 % | Marshall Wace LLP | 275.074 | 275.074 | 31.12.2024 |
0,33968 % | Young (Jonathan) | 270.453 | -10.000 | 3.2.2025 |
0,33884 % | abrdn Inc. | 269.782 | 146.424 | 31.12.2024 |
0,33243 % | Simplify Asset Management Inc | 264.677 | -19.089 | 31.12.2024 |
0,33076 % | Fred Alger Management, LLC | 263.353 | -6.248 | 31.12.2024 |
0,32943 % | Schonfeld Strategic Advisors LLC | 262.295 | -16.028 | 31.12.2024 |
0,32655 % | B Group, Inc. | 260.000 | 260.000 | 31.12.2024 |
0,28887 % | Cutter Capital Management, LP | 230.000 | 230.000 | 31.12.2024 |
0,28262 % | Jane Street Capital, L.L.C. | 225.019 | 7.455 | 31.12.2024 |
0,24288 % | Great Lakes Advisors, LLC | 193.384 | 193.384 | 31.12.2024 |
0,23928 % | BlackRock Investment Management, LLC | 190.512 | 3.301 | 31.12.2024 |
0,21979 % | Hudson Bay Capital Management LP | 175.000 | 20.000 | 31.12.2024 |
0,21308 % | TD Asset Management Inc. | 169.654 | 46.200 | 31.12.2024 |
0,21163 % | Nuveen LLC | 168.498 | -3.385 | 31.12.2024 |
0,21153 % | Two Sigma Investments, LP | 168.420 | 65.700 | 31.12.2024 |
0,20723 % | 5AM Ventures | 165.000 | 165.000 | 31.12.2024 |
0,20324 % | DWS Investment GmbH | 161.823 | 20.950 | 31.12.2024 |
0,19473 % | Ensign Peak Advisors, Inc. | 155.044 | 0 | 31.12.2024 |
0,18990 % | Springhill Fund Asset Management (HK) Company Limited | 151.200 | 151.200 | 31.12.2024 |
0,17210 % | PDT Partners, LLC | 137.030 | -2.266 | 31.12.2024 |
0,17128 % | Norges Bank Investment Management (NBIM) | 136.377 | -134.199 | 30.6.2023 |
0,16918 % | Walleye Capital LLC | 134.705 | 134.705 | 31.12.2024 |
0,16485 % | Barclays Bank PLC | 131.255 | 5.169 | 31.12.2024 |
0,15648 % | Manulife Investment Management (North America) Limited | 124.592 | 28.043 | 31.12.2024 |
0,15642 % | Rolph (Timothy Peter) | 124.543 | 0 | 5.2.2025 |
0,15583 % | BNY Mellon Asset Management | 124.075 | -7.356 | 31.12.2024 |
0,15329 % | J.P. Morgan Securities LLC | 122.046 | 121.586 | 31.12.2024 |
0,14122 % | American Century Investment Management, Inc. | 112.442 | 39.932 | 31.12.2024 |
0,14031 % | DWS Investments UK Limited | 111.716 | -81.807 | 31.12.2024 |
0,13274 % | Rhumbline Advisers Ltd. Partnership | 105.686 | 1.310 | 31.12.2024 |
0,12007 % | Schweizerische Nationalbank | 95.600 | 1.100 | 31.12.2024 |
0,11042 % | Citi Investment Research (US) | 87.917 | 36.036 | 31.12.2024 |
0,10529 % | BlackRock Advisors (UK) Limited | 83.829 | 45 | 31.1.2025 |
0,10446 % | Goldman Sachs Asset Management, L.P. | 83.173 | -37.701 | 31.12.2024 |
0,10299 % | Avidity Partners Management LP | 82.000 | 82.000 | 31.12.2024 |
0,10047 % | T. Rowe Price International Ltd | 79.996 | -18.256 | 31.12.2024 |
0,09510 % | Mellon Investments Corporation | 75.719 | 620 | 31.12.2024 |
0,09224 % | Aperio Group, LLC | 73.443 | -2.118 | 31.12.2024 |
0,09119 % | Rafferty Asset Management LLC | 72.604 | -17.797 | 31.12.2024 |
0,09084 % | BlackRock Asset Management Ireland Limited | 72.329 | 1.147 | 31.12.2024 |
0,08617 % | Exome Asset Management LLC | 68.608 | -8.492 | 31.12.2024 |
0,08536 % | Cinctive Capital Management LP | 67.964 | 2.657 | 31.12.2024 |
0,08289 % | OrbiMed Advisors, LLC | 66.000 | 66.000 | 31.12.2024 |
0,08206 % | Invesco Capital Management LLC | 65.338 | 8.746 | 31.12.2024 |
0,07502 % | Algert Global LLC | 59.734 | -8.318 | 31.12.2024 |
0,07205 % | JPMorgan Private Bank (United States) | 57.370 | -3.199 | 31.12.2024 |
0,07089 % | Alps Advisors, Inc. | 56.440 | 3.405 | 31.12.2024 |
0,06934 % | ExodusPoint Capital Management, LP | 55.207 | 7.575 | 31.12.2024 |
0,06290 % | Legal & General Investment Management Ltd. | 50.080 | -5.482 | 31.12.2024 |
0,06274 % | Yale (Catriona) | 49.954 | 0 | 27.1.2025 |
0,06187 % | Parametric Portfolio Associates LLC | 49.263 | 12.001 | 31.12.2024 |
0,05991 % | Atom Investors LP | 47.700 | 47.700 | 31.12.2024 |
0,05903 % | Erste Asset Management GmbH | 47.000 | 0 | 31.12.2024 |
0,05882 % | California State Teachers Retirement System | 46.835 | -373 | 31.12.2024 |
0,05759 % | Morgan Stanley Smith Barney LLC | 45.851 | 18.923 | 31.12.2024 |