9,96069 % | Baillie Gifford & Co. | 14.260.724 | -420.303 | 31.12.2023 |
8,90645 % | Biogen Inc | 12.751.365 | -558.878 | 31.12.2023 |
7,55056 % | The Vanguard Group, Inc. | 10.810.137 | 232.597 | 31.12.2023 |
6,61220 % | BlackRock Institutional Trust Company, N.A. | 9.466.684 | 693.719 | 31.12.2023 |
5,08117 % | Wellington Management Company, LLP | 7.274.717 | -14.243 | 31.12.2023 |
4,81665 % | Temasek Holdings Pte. Ltd. | 6.895.992 | 0 | 31.12.2023 |
3,95385 % | Crestline Investors, Inc. | 5.660.732 | -300.000 | 31.12.2023 |
3,83177 % | State Street Global Advisors (US) | 5.485.948 | 1.210.620 | 31.12.2023 |
2,03222 % | Capital Research Global Investors | 2.909.528 | 29.205 | 31.12.2023 |
1,85744 % | Geode Capital Management, L.L.C. | 2.659.296 | 127.461 | 31.12.2023 |
1,82105 % | Baker Bros. Advisors LP | 2.607.196 | 315.193 | 31.12.2023 |
1,73872 % | T. Rowe Price Associates, Inc. | 2.489.326 | -316.720 | 31.12.2023 |
1,62043 % | Flagship Ventures | 2.319.968 | -300.000 | 31.12.2023 |
1,62034 % | Watts (Ryan J) | 2.319.844 | -9.589 | 13.2.2024 |
1,47060 % | Tessier-Lavigne (Marc) | 2.105.455 | 4.216 | 1.6.2023 |
1,16463 % | Marshall Wace LLP | 1.667.397 | 1.667.397 | 31.12.2023 |
1,09444 % | Credit Suisse Funds AG | 1.566.904 | 7.868 | 31.12.2023 |
0,94426 % | Federated Hermes Global Investment Management Corp. | 1.351.900 | 0 | 31.12.2023 |
0,90801 % | Casdin Capital, LLC | 1.300.000 | 0 | 31.12.2023 |
0,85171 % | Gilder Gagnon Howe & Co. LLC | 1.219.392 | -26.807 | 31.12.2023 |
0,84901 % | Mellon Investments Corporation | 1.215.533 | -17.304 | 31.12.2023 |
0,80509 % | Norges Bank Investment Management (NBIM) | 1.152.646 | 128.440 | 31.12.2023 |
0,80372 % | Yiheng Capital Management, L.P. | 1.150.684 | 0 | 31.12.2023 |
0,78203 % | Dimensional Fund Advisors, L.P. | 1.119.628 | 146.394 | 31.12.2023 |
0,74995 % | Principal Global Investors (Equity) | 1.073.704 | 393.626 | 31.12.2023 |
0,72130 % | BlackRock Financial Management, Inc. | 1.032.692 | -17.071 | 31.12.2023 |
0,70336 % | Charles Schwab Investment Management, Inc. | 1.006.997 | 25.938 | 31.12.2023 |
0,69919 % | Northern Trust Investments, Inc. | 1.001.025 | 23.415 | 31.12.2023 |
0,60422 % | Krognes (Steve E) | 865.055 | -92.500 | 1.4.2024 |
0,56080 % | Invus Public Equities Advisors, LLC | 802.899 | 0 | 31.12.2023 |
0,45010 % | Point72 Asset Management, L.P. | 644.406 | 644.406 | 31.12.2023 |
0,44818 % | Fidelity Management & Research Company LLC | 641.653 | -416.844 | 31.12.2023 |
0,44447 % | UBS Asset Management (Switzerland) | 636.345 | 59.807 | 31.12.2023 |
0,43654 % | Cercano Management LLC | 625.000 | 0 | 31.12.2023 |
0,43389 % | Schuth (Alexander O) | 621.203 | 27.156 | 14.2.2024 |
0,40807 % | Morgan Stanley & Co. LLC | 584.237 | -14.389 | 31.12.2023 |
0,36564 % | BlackRock Advisors (UK) Limited | 523.482 | -2.250 | 31.3.2024 |
0,34852 % | T. Rowe Price Investment Management, Inc. | 498.969 | -148.044 | 31.12.2023 |
0,34568 % | BlackRock Asset Management Ireland Limited | 494.916 | -18.688 | 31.12.2023 |
0,33072 % | American Century Investment Management, Inc. | 473.494 | -842 | 31.12.2023 |
0,32253 % | Braidwell LP | 461.769 | 461.769 | 31.12.2023 |
0,31618 % | Polar Capital LLP | 452.669 | -554.417 | 31.12.2023 |
0,30678 % | Pictet Asset Management Ltd. | 439.218 | -150.281 | 31.12.2023 |
0,30028 % | BofA Global Research (US) | 429.915 | 172.486 | 31.12.2023 |
0,28391 % | BNY Mellon Asset Management | 406.476 | 6.807 | 31.12.2023 |
0,28125 % | Wasatch Global Investors Inc | 402.670 | 90.369 | 31.3.2024 |
0,27395 % | The Clarius Group, LLC | 392.218 | 13.956 | 31.3.2024 |
0,26817 % | Artisan Partners Limited Partnership | 383.942 | -22.680 | 31.12.2023 |
0,26743 % | Candriam Luxembourg S.A. | 382.878 | 25.000 | 29.2.2024 |
0,26629 % | ARCH Venture Partners | 381.249 | -312.500 | 31.12.2023 |
0,24997 % | Candriam Belgium S.A. | 357.878 | 0 | 31.12.2023 |
0,24705 % | AXA Investment Managers UK Ltd. | 353.695 | 866 | 31.12.2023 |
0,24341 % | Ensign Peak Advisors, Inc. | 348.497 | 0 | 31.12.2023 |
0,24321 % | SEB Investment Management AB | 348.203 | 0 | 31.12.2023 |
0,23072 % | Flatley (Jay T) | 330.327 | 2.074 | 31.3.2023 |
0,22688 % | abrdn Inc. | 324.829 | 324.829 | 31.12.2023 |
0,22688 % | Tekla Capital Management LLC_NLE | 324.829 | 0 | 30.6.2023 |
0,22632 % | Barclays Bank PLC | 324.019 | 157.512 | 31.12.2023 |
0,22489 % | Rafferty Asset Management LLC | 321.973 | 92.660 | 31.12.2023 |
0,22070 % | Nuveen LLC | 315.981 | -47.684 | 31.12.2023 |
0,22038 % | Eagle Asset Management, Inc. | 315.520 | 26.387 | 31.12.2023 |
0,21221 % | BlackRock Investment Management, LLC | 303.825 | 2.788 | 31.12.2023 |
0,20324 % | UBS Financial Services, Inc. | 290.985 | 181.289 | 31.12.2023 |
0,19180 % | Voya Investment Management LLC | 274.607 | 19.127 | 31.12.2023 |
0,18868 % | Goldman Sachs & Company, Inc. | 270.135 | 108.858 | 31.12.2023 |
0,18201 % | Balyasny Asset Management LP | 260.587 | 260.587 | 31.12.2023 |
0,17677 % | Ho (Carole) | 253.082 | -4.189 | 14.2.2024 |
0,17196 % | Mitsubishi UFJ Trust and Banking Corporation | 246.190 | -44.770 | 31.12.2023 |
0,15171 % | Baillie Gifford Overseas Ltd. | 217.209 | 0 | 29.2.2024 |
0,15136 % | Schweizerische Nationalbank | 216.700 | -24.100 | 31.12.2023 |
0,14950 % | Morgan Stanley Smith Barney LLC | 214.042 | -42.259 | 31.12.2023 |
0,14691 % | Newton Investment Management North America, LLC | 210.334 | -72.930 | 31.12.2023 |
0,14573 % | Kentucky Teachers' Retirement System | 208.644 | -9.550 | 31.12.2023 |
0,13969 % | ACATIS Investment Kapitalverwaltungsgesellschaft GmbH | 200.000 | 0 | 31.1.2024 |
0,13801 % | Woodline Partners LP | 197.584 | -653.905 | 31.12.2023 |
0,13386 % | BNP Paribas Securities Corp. North America | 191.643 | 28.817 | 31.12.2023 |
0,12302 % | California Public Employees' Retirement System | 176.131 | 0 | 31.12.2023 |
0,12223 % | Hudson Bay Capital Management LP | 175.000 | 175.000 | 31.12.2023 |
0,12169 % | Pier Capital, LLC | 174.219 | 49.139 | 31.12.2023 |
0,11962 % | Qube Research & Technologies Ltd | 171.262 | 157.709 | 31.12.2023 |
0,11648 % | Rhumbline Advisers Ltd. Partnership | 166.763 | -2.361 | 31.12.2023 |
0,11572 % | Edmond de Rothschild Asset Management (France) S.A. | 165.680 | 65.800 | 31.12.2023 |
0,11548 % | Jefferies LLC | 165.327 | 152.527 | 31.12.2023 |
0,11311 % | Renaissance Technologies LLC | 161.946 | -305.905 | 31.12.2023 |
0,11003 % | BlackRock Investment Management (UK) Ltd. | 157.534 | -9.519 | 31.12.2023 |
0,10756 % | Schroder Investment Management Ltd. (SIM) | 154.000 | 154.000 | 31.12.2023 |
0,10756 % | International Biotechnology Trust PLC | 154.000 | -34.000 | 30.9.2023 |
0,10405 % | Jane Street Capital, L.L.C. | 148.965 | 110.226 | 31.12.2023 |
0,10321 % | Parametric Portfolio Associates LLC | 147.769 | 52.705 | 31.12.2023 |
0,10090 % | Neuberger Berman, LLC | 144.461 | 144.461 | 31.12.2023 |
0,09868 % | Citi Investment Research (US) | 141.276 | 2.967 | 31.12.2023 |
0,09776 % | AllianceBernstein L.P. | 139.960 | 3.200 | 31.12.2023 |
0,09541 % | New Jersey Division of Investment | 136.600 | 29.511 | 31.12.2023 |
0,09429 % | SELECTRA Management Company S.A. | 135.000 | 0 | 30.6.2023 |
0,09080 % | Soleus Capital Management, L.P. | 130.000 | 130.000 | 31.12.2023 |
0,08659 % | New York State Common Retirement Fund | 123.974 | -5.879 | 31.12.2023 |
0,08197 % | California State Teachers Retirement System | 117.351 | -5.553 | 31.12.2023 |
0,07827 % | Sato (Vicki Lee) | 112.057 | -1.666 | 15.4.2024 |
0,07786 % | Russell Investments Trust Company | 111.473 | -2.585 | 31.12.2023 |
0,07454 % | Legal & General Investment Management Ltd. | 106.713 | 888 | 31.12.2023 |