٧٫٤٧٩٧٦ % | Avoro Capital Advisors LLC | ٥٬٦٦٦٬٦٦٦ | 0 | ٣٠/٦/٢٠٢٤ |
٧٫٢٨١١٥ % | Fidelity Management & Research Company LLC | ٥٬٥١٦٬٢٠٢ | ٥٠٥ | ٣٠/٦/٢٠٢٤ |
٦٫٩٢٩٨٤ % | Capital Research Global Investors | ٥٬٢٥٠٬٠٤٣ | ٩٣٬٣٧٧ | ٣٠/٩/٢٠٢٤ |
٥٫٨٣٣٥٢ % | Driehaus Capital Management, LLC | ٤٬٤١٩٬٤٧٢ | ٩٧٬٧٣٢ | ٣٠/٦/٢٠٢٤ |
٥٫٠٥٣٠٩ % | Wellington Management Company, LLP | ٣٬٨٢٨٬٢٢١ | -٩٣٬٨٣٧ | ٣٠/٦/٢٠٢٤ |
٣٫٦٣٥٥١ % | Commodore Capital LP | ٢٬٧٥٤٬٢٦٦ | ٥٨٦٬٤٧٣ | ٣٠/٦/٢٠٢٤ |
٣٫٥٣٩٥٢ % | Capital World Investors | ٢٬٦٨١٬٥٣٧ | 0 | ٣٠/٦/٢٠٢٤ |
٣٫٣٧٩٨٥ % | Braidwell LP | ٢٬٥٦٠٬٥٧٣ | ١٬٢٥٢٬٥٦٢ | ٣٠/٦/٢٠٢٤ |
٣٫٣٤٧٤٩ % | Polar Capital LLP | ٢٬٥٣٦٬٠٥٨ | -٧٦٬٠٥٠ | ٣٠/٦/٢٠٢٤ |
٣٫٢٦٨٠٣ % | Capital International Investors | ٢٬٤٧٥٬٨٥٩ | 0 | ٣٠/٦/٢٠٢٤ |
٢٫٦٩٧٠٤ % | Paradigm BioCapital Advisors LP | ٢٬٠٤٣٬٢٨٠ | -٤٤١٬٥٩٤ | ٣٠/٦/٢٠٢٤ |
٢٫٤٢٨١٣ % | Adage Capital Management, L.P. | ١٬٨٣٩٬٥٥٥ | ١٦٧٬٦٣٨ | ٣٠/٦/٢٠٢٤ |
١٫٩٥٧٧٢ % | AllianceBernstein L.P. | ١٬٤٨٣٬١٦٦ | ١٤٬٧٢٠ | ٣٠/٦/٢٠٢٤ |
١٫٩٥٢٨٧ % | Pictet Asset Management Ltd. | ١٬٤٧٩٬٤٩١ | -٣٥٬٩٣٥ | ٣٠/٦/٢٠٢٤ |
١٫٩٠٠٦١ % | T. Rowe Price Investment Management, Inc. | ١٬٤٣٩٬٩٠٣ | ١٣٬٥٦٤ | ٣٠/٦/٢٠٢٤ |
١٫٨٢٧٧١ % | Marshall Wace LLP | ١٬٣٨٤٬٦٧٤ | -٦٥٬٦٦٨ | ٣٠/٦/٢٠٢٤ |
١٫٧٢٤٢١ % | First Light Asset Management, LLC | ١٬٣٠٦٬٢٦٠ | -١٣٬٩١٢ | ٣٠/٦/٢٠٢٤ |
١٫٦٨٠١٤ % | Rock Springs Capital Management LP | ١٬٢٧٢٬٨٧٧ | ١٧٬٣٠٠ | ٣٠/٦/٢٠٢٤ |
١٫٦٥٢٥٥ % | Fidelity Institutional Asset Management | ١٬٢٥١٬٩٧١ | ١٦٥٬٨٣٨ | ٣٠/٦/٢٠٢٤ |
١٫٣٧٩٧٠ % | Janus Henderson Investors | ١٬٠٤٥٬٢٥٧ | ١٠٣٬٦٨٨ | ٣٠/٦/٢٠٢٤ |
١٫٣١٢٣٤ % | Affinity Asset Advisors LLC | ٩٩٤٬٢٢٧ | ١٥٦٬٨٤٠ | ٣٠/٦/٢٠٢٤ |
١٫٣١١٦١ % | Baker Bros. Advisors LP | ٩٩٣٬٦٧٩ | 0 | ٣٠/٦/٢٠٢٤ |
١٫٢٧٩٧٩ % | BlackRock Financial Management, Inc. | ٩٦٩٬٥٦٩ | ٤٦٬٠٣٢ | ٣٠/٦/٢٠٢٤ |
١٫١٣٨٢٨ % | OrbiMed Advisors, LLC | ٨٦٢٬٣٦٢ | ٣١٢٬٣٦٢ | ٣٠/٦/٢٠٢٤ |
١٫٠٢٩٥٩ % | Invesco Advisers, Inc. | ٧٨٠٬٠١٦ | -٢٥٬٦٥٠ | ٣٠/٦/٢٠٢٤ |
١٫٠١٤٦٩ % | Citadel Advisors LLC | ٧٦٨٬٧٢٦ | -٥١٨٬٣٤٩ | ٣٠/٦/٢٠٢٤ |
٠٫٩٩٥٩٠ % | TimesSquare Capital Management, LLC | ٧٥٤٬٤٩٣ | ١٧٬٣٢٠ | ٣٠/٦/٢٠٢٤ |
٠٫٩٩٥٢٥ % | Avidity Partners Management LP | ٧٥٤٬٠٠٠ | ٤٤٬٠٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫٩٩١٩٤ % | BlackRock Institutional Trust Company, N.A. | ٧٥١٬٤٩٠ | ١٤٬٣٩٠ | ٣٠/٦/٢٠٢٤ |
٠٫٩٦٩٥٨ % | Federated Hermes Global Investment Management Corp. | ٧٣٤٬٥٥٥ | -٣٤٥ | ٣٠/٦/٢٠٢٤ |
٠٫٨٧١٥١ % | Loomis, Sayles & Company, L.P. | ٦٦٠٬٢٥٨ | -٢٦٬٢٥٢ | ٣٠/٦/٢٠٢٤ |
٠٫٨٤٩٤٥ % | Westfield Capital Management Company, L.P. | ٦٤٣٬٥٤٦ | ٢٩٦٬١٩٥ | ٣٠/٦/٢٠٢٤ |
٠٫٨٤٤٣٦ % | Samlyn Capital, LLC | ٦٣٩٬٦٨٥ | ٢٤٣٬٤٨٩ | ٣٠/٦/٢٠٢٤ |
٠٫٧٩١٩٧ % | Boxer Capital, L.L.C. | ٦٠٠٬٠٠٠ | 0 | ٣٠/٦/٢٠٢٤ |
٠٫٧٦٩٨٧ % | Perceptive Advisors LLC | ٥٨٣٬٢٥٦ | -٣٠٨٬٩٥٢ | ٣٠/٦/٢٠٢٤ |
٠٫٧٥٧٩٣ % | Fiera Capital Inc. | ٥٧٤٬٢١١ | ٣٬٨٩٣ | ٣٠/٦/٢٠٢٤ |
٠٫٧٥٢٧٣ % | Jennison Associates LLC | ٥٧٠٬٢٧٢ | ٦٬٣٢٠ | ٣٠/٦/٢٠٢٤ |
٠٫٦٩٢٩٨ % | Vestal Point Capital, LP | ٥٢٥٬٠٠٠ | ١٢٥٬٠٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫٦٨٨٨٠ % | Candriam Belgium S.A. | ٥٢١٬٨٣٦ | -٣٩٬٠٤٨ | ٣٠/٦/٢٠٢٤ |
٠٫٦٣٦٢٥ % | Point72 Asset Management, L.P. | ٤٨٢٬٠٢٢ | ٢٠٦٬١٦٣ | ٣٠/٦/٢٠٢٤ |
٠٫٦١٢٢٨ % | Candriam Luxembourg S.A. | ٤٦٣٬٨٦١ | 0 | ٣٠/٩/٢٠٢٤ |
٠٫٥٧٦١١ % | Dimensional Fund Advisors, L.P. | ٤٣٦٬٤٦٠ | ٢٦٬٢٥٣ | ٣٠/٦/٢٠٢٤ |
٠٫٥٣٣٣٠ % | Two Sigma Investments, LP | ٤٠٤٬٠٢٩ | -٩٩٬٧٩٧ | ٣٠/٦/٢٠٢٤ |
٠٫٥٠٦٩٤ % | BNP Paribas Asset Management USA, Inc. | ٣٨٤٬٠٥٨ | ٢٬٦٠٥ | ٣٠/٦/٢٠٢٤ |
٠٫٥٠٣٦٤ % | Invus Public Equities Advisors, LLC | ٣٨١٬٥٥٤ | ١٢٨٬١٦٧ | ٣٠/٦/٢٠٢٤ |
٠٫٤٩٤٩٨ % | Logos Global Management LLC | ٣٧٥٬٠٠٠ | ٣٧٥٬٠٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫٤٨٢٨٨ % | Norges Bank Investment Management (NBIM) | ٣٦٥٬٨٣٠ | ٢٣١٬٣٧٢ | ٣١/٣/٢٠٢٣ |
٠٫٤٧٥٩٨ % | Altium Capital Management LP | ٣٦٠٬٦٠٠ | ١٢٬٦٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫٤٧١٤٦ % | ExodusPoint Capital Management, LP | ٣٥٧٬١٧٨ | ٢٠٣٬١٤٠ | ٣٠/٦/٢٠٢٤ |
٠٫٤٤٨٦٢ % | First Turn Management, LLC | ٣٣٩٬٨٧٦ | -٣٤٠٬٥١٣ | ٣٠/٦/٢٠٢٤ |
٠٫٤٣٨٧٨ % | Goldman Sachs & Company, Inc. | ٣٣٢٬٤٢١ | ٦٢٬٧٥٧ | ٣٠/٦/٢٠٢٤ |
٠٫٤٣٣١٣ % | The Vanguard Group, Inc. | ٣٢٨٬١٤٣ | ٥٬٥١٧ | ٣٠/٦/٢٠٢٤ |
٠٫٤٢٤١٤ % | Medical Strategy GmbH | ٣٢١٬٣٣٢ | -٤٬٦٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫٣٨٧٨٤ % | Franklin Advisers, Inc. | ٢٩٣٬٨٢٥ | 0 | ٣٠/٦/٢٠٢٤ |
٠٫٣٨٥٢٥ % | Alyeska Investment Group, L.P. | ٢٩١٬٨٦٨ | ٥٣٬٠٢٥ | ٣٠/٦/٢٠٢٤ |
٠٫٣٧٦٢٤ % | Putnam Investment Management, L.L.C. | ٢٨٥٬٠٤٠ | ٣٦٬٥٧٦ | ٣٠/٦/٢٠٢٤ |
٠٫٣٦١٣٢ % | Dafna Capital Management, LLC | ٢٧٣٬٧٣٩ | 0 | ٣٠/٦/٢٠٢٤ |
٠٫٣٣٠٦٠ % | Boone Capital Management LLC | ٢٥٠٬٤٦٠ | -٤٠٬٩٤٣ | ٣٠/٦/٢٠٢٤ |
٠٫٣٢٧٧٦ % | abrdn Inc. | ٢٤٨٬٣١١ | ٣٥٬٨٠٩ | ٣٠/٩/٢٠٢٤ |
٠٫٣٢٥٧٨ % | State Street Global Advisors (US) | ٢٤٦٬٨١٢ | ٤٬١٧٢ | ٣٠/٦/٢٠٢٤ |
٠٫٣٠٧٩٩ % | Balyasny Asset Management LP | ٢٣٣٬٣٣٥ | ٣٢٬٠٦١ | ٣٠/٦/٢٠٢٤ |
٠٫٢٩٨٥٣ % | Granahan Investment Management, LLC | ٢٢٦٬١٦٦ | -١٧٬٩١٤ | ٣٠/٦/٢٠٢٤ |
٠٫٢٩٧١٠ % | Morgan Stanley & Co. LLC | ٢٢٥٬٠٨٢ | -١٤١٬٦٤٠ | ٣٠/٦/٢٠٢٤ |
٠٫٢٨٠٢١ % | Assenagon Asset Management S.A. | ٢١٢٬٢٨٧ | ١٣٨٬٦٨٥ | ٣٠/٩/٢٠٢٤ |
٠٫٢٧٦٢٥ % | Parkman Healthcare Partners LLC | ٢٠٩٬٢٩٠ | -١٤٬٦٥٢ | ٣٠/٦/٢٠٢٤ |
٠٫٢٥٠٨٤ % | Lord, Abbett & Co. LLC | ١٩٠٬٠٣٣ | -٧٠٥٬١٦٣ | ٣٠/٦/٢٠٢٤ |
٠٫٢٤٨٢٠ % | AXA Investment Managers UK Ltd. | ١٨٨٬٠٣٨ | ١٦٦ | ٣٠/٦/٢٠٢٤ |
٠٫٢٤١٨٢ % | Algert Global LLC | ١٨٣٬٢٠٥ | -٨١٠ | ٣٠/٦/٢٠٢٤ |
٠٫٢٣١٩٦ % | DNB Asset Management AS | ١٧٥٬٧٣٣ | ٤٩٬٤٨٣ | ٣٠/٦/٢٠٢٤ |
٠٫٢٣١٧٦ % | Millennium Management LLC | ١٧٥٬٥٨٤ | ٩١٬٩٢٣ | ٣٠/٦/٢٠٢٤ |
٠٫٢٢٥٩٧ % | Laurion Capital Management LP | ١٧١٬١٩٥ | -٦٧٬٩٣١ | ٣٠/٦/٢٠٢٤ |
٠٫٢٢٤٠٥ % | BlackRock Investment Management (UK) Ltd. | ١٦٩٬٧٣٨ | ٥٤٬٩٤٤ | ٣٠/٦/٢٠٢٤ |
٠٫٢٢٣٥٦ % | Ally Bridge Group NY LLC | ١٦٩٬٣٦٩ | -١٤٠٬٠٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫٢١٥٢٤ % | Ensign Peak Advisors, Inc. | ١٦٣٬٠٦٤ | 0 | ٣٠/٦/٢٠٢٤ |
٠٫٢١٣٤٧ % | D. E. Shaw & Co., L.P. | ١٦١٬٧٢٢ | -٣٦٬٨٠٤ | ٣٠/٦/٢٠٢٤ |
٠٫٢١٢٦٨ % | BlackRock Advisors (UK) Limited | ١٦١٬١٢٤ | ١٬٤٥٦ | ٣٠/٩/٢٠٢٤ |
٠٫٢٠٨٨٠ % | Russell Investments Trust Company | ١٥٨٬١٨٥ | -١٥٬٠٢١ | ٣٠/٦/٢٠٢٤ |
٠٫١٩٩٣١ % | Nomura Asset Management Co., Ltd. | ١٥١٬٠٠٠ | -٣٤٬٤٠٠ | ٣٠/١١/٢٠٢٣ |
٠٫١٩٨٧٢ % | PFM Health Sciences, LP | ١٥٠٬٥٥٤ | 0 | ٣٠/٦/٢٠٢٤ |
٠٫١٩٣٧٧ % | Bridger Management, LLC | ١٤٦٬٨٠٠ | 0 | ٣٠/٦/٢٠٢٤ |
٠٫١٨٠٥٢ % | BlackRock Asset Management Ireland Limited | ١٣٦٬٧٦١ | -١٥٥٬٥٥٤ | ٣٠/٦/٢٠٢٤ |
٠٫١٧٤٩٢ % | New York State Common Retirement Fund | ١٣٢٬٥٢١ | -١٨٬٣١٩ | ٣٠/٩/٢٠٢٤ |
٠٫١٦٦٤٥ % | Schweizerische Nationalbank | ١٢٦٬١٠٠ | ٢٬٣٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫١٦٣٦٧ % | Atika Capital Management LLC | ١٢٤٬٠٠٠ | ٢٬٠٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫١٤٩٠٠ % | Polen Capital Management, LLC | ١١٢٬٨٨١ | ٢٥٬٧٨٢ | ٣١/٨/٢٠٢٤ |
٠٫١٤٥٢٦ % | Tenax Capital Ltd. | ١١٠٬٠٤٧ | 0 | ٣١/٥/٢٠٢٣ |
٠٫١٤١٤٨ % | Ikarian Capital LLC | ١٠٧٬١٨٧ | 0 | ٣٠/٦/٢٠٢٤ |
٠٫١٤٠٨١ % | Nan Fung Life Sciences | ١٠٦٬٦٨٠ | 0 | ٣٠/٦/٢٠٢٤ |
٠٫١٣٤٥٨ % | Tri Locum Partners LP | ١٠١٬٩٥٩ | -١٠٥٬٥٠٦ | ٣٠/٦/٢٠٢٤ |
٠٫١٣٢١٣ % | Baron Capital Management, Inc. | ١٠٠٬١٠٠ | 0 | ٣٠/٦/٢٠٢٤ |
٠٫١٢٧٥٩ % | Principal Global Investors (Equity) | ٩٦٬٦٦٢ | -٦٬٩٢٠ | ٣١/٨/٢٠٢٤ |
٠٫١٢٢٦٢ % | Renaissance Technologies LLC | ٩٢٬٩٠٠ | ٣٦٬٥٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫١٢٠٧٨ % | Schroder Investment Management Ltd. (SIM) | ٩١٬٥٠٠ | 0 | ٣٠/٦/٢٠٢٤ |
٠٫١٢٠٧٨ % | International Biotechnology Trust PLC | ٩١٬٥٠٠ | ٦٦٬٠٠٠ | ٣٠/٩/٢٠٢٣ |
٠٫١١٨٥٣ % | State of Wisconsin Investment Board | ٨٩٬٨٠٠ | -١٬٩٨٥ | ٣٠/٦/٢٠٢٤ |
٠٫١١٧٠٩ % | TwinBeech Capital LP | ٨٨٬٧١١ | -٩٬٣٣١ | ٣٠/٦/٢٠٢٤ |
٠٫١١٦٥١ % | MFS Investment Management | ٨٨٬٢٦٧ | -٧٠٤ | ٣١/٨/٢٠٢٤ |
٠٫١١١٦٣ % | New Jersey Division of Investment | ٨٤٬٥٧٣ | -٨٬١٧٧ | ٣٠/٦/٢٠٢٤ |
٠٫١٠٩٥٦ % | Victory Capital Management Inc. | ٨٢٬٩٩٩ | -١٤٬٣٥٤ | ٣٠/٦/٢٠٢٤ |
٠٫٠٩٨٩٠ % | Neuberger Berman, LLC | ٧٤٬٩٢٦ | ١٢٬٨٩٦ | ٣٠/٦/٢٠٢٤ |