10,59759 % | RTW Investments L.P. | 4.543.895 | 709.101 | 30/6/2025 |
7,44113 % | TD Securities, Inc. | 3.190.510 | 1.441.368 | 30/6/2025 |
5,43901 % | Paradigm BioCapital Advisors LP | 2.332.066 | 2.332.066 | 5/8/2025 |
5,13018 % | Jefferies LLC | 2.199.652 | 1.384.652 | 30/6/2025 |
5,09601 % | Soleus Capital Management, L.P. | 2.185.000 | 2.185.000 | 30/6/2025 |
4,91688 % | BlackRock Institutional Trust Company, N.A. | 2.108.194 | -34.563 | 30/6/2025 |
4,71697 % | SilverArc Capital Management, LLC | 2.022.482 | 641.324 | 30/6/2025 |
3,46381 % | Pontifax Venture Capital | 1.485.168 | -1 | 14/3/2024 |
3,44004 % | Morgan Stanley & Co. LLC | 1.474.976 | 1.273.787 | 30/6/2025 |
3,19361 % | Arkin Communication, Ltd. | 1.369.315 | 0 | 22/2/2024 |
3,07860 % | UBS Asset Management Switzerland AG | 1.320.000 | 0 | 31/1/2025 |
2,93807 % | Acorn Capital Advisors, LLC | 1.259.749 | -256.554 | 30/6/2025 |
2,68801 % | Menora Mivtachim Insurance Ltd. | 1.152.531 | -1.150.500 | 30/6/2025 |
2,67997 % | SG Americas Securities, L.L.C. | 1.149.081 | 986.567 | 30/6/2025 |
2,33227 % | Tang Capital Management, LLC | 1.000.000 | 1.000.000 | 30/6/2025 |
2,25997 % | Morgan Stanley Investment Management Inc. (US) | 969.001 | 345.801 | 30/6/2025 |
1,95588 % | Monograph Capital Partners I LP | 838.615 | 838.615 | 5/6/2025 |
1,93578 % | Adage Capital Management, L.P. | 830.000 | -447.000 | 30/6/2025 |
1,88363 % | State Street Global Advisors (US) | 807.638 | 12.626 | 30/6/2025 |
1,79797 % | Migdal Insurance and Financial Holdings Ltd | 770.909 | -15.563 | 30/6/2025 |
1,53130 % | Kynam Capital Management LP | 656.573 | 631.573 | 30/6/2025 |
1,49251 % | Medical Strategy GmbH | 639.941 | 52.263 | 30/11/2024 |
1,38544 % | Millennium Management LLC | 594.031 | 170.446 | 30/6/2025 |
1,34105 % | Boxer Capital Management, LLC | 575.000 | 575.000 | 30/6/2025 |
1,26688 % | Citadel Advisors LLC | 543.196 | 353.519 | 30/6/2025 |
1,26494 % | Rosalind Advisors, Inc. | 542.366 | -407.634 | 30/6/2025 |
1,15589 % | Wildcat Capital Management, LLC | 495.606 | 0 | 30/6/2025 |
1,13074 % | Susquehanna International Group, LLP | 484.823 | 392.798 | 30/6/2025 |
1,11576 % | OrbiMed Advisors, LLC | 478.400 | 478.400 | 30/6/2025 |
1,09786 % | Geode Capital Management, L.L.C. | 470.726 | -2.604 | 30/6/2025 |
0,95318 % | Belldegrun (Arie S) | 408.693 | 0 | 30/6/2025 |
0,89767 % | Citi Investment Research (US) | 384.891 | 355.614 | 30/6/2025 |
0,85902 % | J.P. Morgan Securities LLC | 368.318 | 18.878 | 30/6/2025 |
0,81516 % | Dafna Capital Management, LLC | 349.515 | -143.000 | 30/6/2025 |
0,80734 % | Walleye Capital LLC | 346.162 | 346.162 | 30/6/2025 |
0,79730 % | T. Rowe Price Associates, Inc. | 341.856 | -10.136 | 30/6/2025 |
0,76193 % | Barrett (Elizabeth A) | 326.691 | 0 | 30/6/2025 |
0,74072 % | Atom Investors LP | 317.596 | -82.964 | 30/6/2025 |
0,71536 % | Woodline Partners LP | 306.724 | 353 | 30/6/2025 |
0,69088 % | UBS Financial Services, Inc. | 296.227 | 187.063 | 30/6/2025 |
0,67140 % | Rice Hall James & Associates, LLC | 287.874 | 32.083 | 30/6/2025 |
0,61832 % | BofA Global Research (US) | 265.117 | 68.315 | 30/6/2025 |
0,61055 % | PanAgora Asset Management Inc. | 261.785 | 168.908 | 30/6/2025 |
0,59466 % | The Vanguard Group, Inc. | 254.971 | 4.542 | 30/6/2025 |
0,59301 % | Goldman Sachs & Company, Inc. | 254.264 | 5.999 | 30/6/2025 |
0,58159 % | Northern Trust Investments, Inc. | 249.365 | -18.615 | 30/6/2025 |
0,54009 % | AQR Capital Management, LLC | 231.574 | 117.508 | 30/6/2025 |
0,51039 % | Cubist Systematic Strategies, LLC | 218.837 | 218.837 | 30/6/2025 |
0,50960 % | Schonfeld Strategic Advisors LLC | 218.500 | 148.711 | 30/6/2025 |
0,44176 % | Two Sigma Investments, LP | 189.412 | 172.124 | 30/6/2025 |
0,43154 % | Simplex Trading, LLC | 185.030 | 184.698 | 30/6/2025 |
0,41212 % | Parkman Healthcare Partners LLC | 176.702 | -216.451 | 30/6/2025 |
0,39364 % | Point72 Asset Management, L.P. | 168.779 | -67.227 | 30/6/2025 |
0,38738 % | ARK Investment Management LLC | 166.094 | -19.696 | 30/6/2025 |
0,36862 % | Wellington Management Company, LLP | 158.052 | 9.974 | 30/6/2025 |
0,36797 % | Harel Insurance Investments and Financial Services Ltd | 157.772 | -216.210 | 30/6/2025 |
0,34984 % | Diadema Partners LP | 150.000 | 73.780 | 30/6/2025 |
0,34350 % | Jane Street Capital, L.L.C. | 147.280 | 96.103 | 30/6/2025 |
0,33441 % | Schoenberg (Mark) | 143.382 | -10.000 | 11/8/2025 |
0,29645 % | BlackRock Financial Management, Inc. | 127.107 | 39.773 | 30/6/2025 |
0,28919 % | BlackRock Investment Management, LLC | 123.994 | 22.299 | 30/6/2025 |
0,25100 % | Privium Fund Management BV | 107.622 | 0 | 30/6/2025 |
0,24308 % | HRT Financial LP | 104.226 | 104.226 | 30/6/2025 |
0,24133 % | Wells Fargo Advisors | 103.476 | -93.444 | 30/6/2025 |
0,21995 % | Squarepoint Capital LLP | 94.309 | 61.545 | 30/6/2025 |
0,21666 % | Charles Schwab Investment Management, Inc. | 92.898 | -649 | 30/6/2025 |
0,21480 % | RBC Dominion Securities, Inc. | 92.100 | 92.100 | 30/6/2025 |
0,20503 % | Superstring Capital Management LP | 87.912 | -335.720 | 30/6/2025 |
0,18981 % | Nuveen LLC | 81.383 | -9.811 | 30/6/2025 |
0,17980 % | Valu-Trac Investment Management Ltd. | 77.093 | -1.234 | 31/3/2024 |
0,17621 % | Annandale Capital, LLC | 75.552 | 0 | 30/6/2025 |
0,16774 % | BNP Paribas Securities Corp. North America | 71.921 | 69.503 | 30/6/2025 |
0,16459 % | Oak Ridge Investments, LLC | 70.570 | -3.134 | 30/6/2025 |
0,15741 % | Barclays Bank PLC | 67.493 | 22.953 | 30/6/2025 |
0,14067 % | Voya Investment Management LLC | 60.314 | 50.222 | 30/6/2025 |
0,13643 % | BNY Mellon Asset Management | 58.497 | 372 | 30/6/2025 |
0,12454 % | TD Asset Management Inc. | 53.400 | 0 | 30/6/2025 |
0,11963 % | Rhumbline Advisers Ltd. Partnership | 51.293 | -2.173 | 30/6/2025 |
0,10516 % | Kim (Dong) | 45.087 | 0 | 30/6/2025 |
0,09677 % | Smith (Jason Drew) | 41.492 | 8.978 | 28/7/2025 |
0,08945 % | Hennion & Walsh Asset Management, Inc. | 38.355 | 38.355 | 30/6/2025 |
0,08909 % | Renaissance Technologies LLC | 38.200 | -52.400 | 30/6/2025 |
0,08740 % | Manulife Investment Management (North America) Limited | 37.476 | -706 | 30/6/2025 |
0,08629 % | Coastal Bridge Advisors, LLC | 37.000 | 0 | 30/6/2025 |
0,08469 % | Goldman Sachs Asset Management, L.P. | 36.313 | 244 | 30/6/2025 |
0,08428 % | Meitav Dash Investments Ltd. | 36.138 | 0 | 30/6/2025 |
0,08172 % | AllianceBernstein L.P. | 35.040 | -35.377 | 30/6/2025 |
0,08117 % | Kovitz Investment Group Partners, LLC | 34.802 | 3.511 | 30/6/2025 |
0,08103 % | Mellon Investments Corporation | 34.743 | -622 | 30/6/2025 |
0,08093 % | Robert Bender & Associates | 34.701 | 34.701 | 30/6/2025 |
0,08070 % | Persistent Asset Partners Limited | 34.600 | 17.029 | 30/6/2025 |
0,07931 % | Virtu Americas LLC | 34.004 | 34.004 | 30/6/2025 |
0,07569 % | Los Angeles Capital Management LLC | 32.453 | 32.453 | 30/6/2025 |
0,07202 % | Columbia Threadneedle Investments (US) | 30.880 | -2.878 | 30/6/2025 |
0,07195 % | Truist Bank | 30.850 | 30.850 | 30/6/2025 |
0,06398 % | D. E. Shaw & Co., L.P. | 27.432 | 27.432 | 30/6/2025 |
0,06337 % | BlackRock Advisors (UK) Limited | 27.169 | 4.158 | 31/7/2025 |
0,06150 % | Cetera Investment Advisers LLC | 26.370 | 26.370 | 30/6/2025 |
0,06103 % | Scientech Research LLC | 26.166 | 26.166 | 30/6/2025 |
0,06056 % | Main Street Financial Solutions, LLC | 25.968 | 1.968 | 30/6/2025 |