15,94397 % | BVF Partners L.P. | 9.135.893 | 0 | 30/6/2024 |
9,60489 % | Paradigm BioCapital Advisors LP | 5.503.600 | -2.400.000 | 1/8/2024 |
6,98080 % | Deep Track Capital LP | 4.000.000 | 774.581 | 30/6/2024 |
6,06310 % | BlackRock Institutional Trust Company, N.A. | 3.474.156 | 671.288 | 30/6/2024 |
5,60546 % | Point72 Asset Management, L.P. | 3.211.927 | 3.211.927 | 30/6/2024 |
5,60013 % | Logos Global Management LLC | 3.208.875 | -1.175.000 | 30/6/2024 |
4,77420 % | The Vanguard Group, Inc. | 2.735.614 | 334.976 | 30/6/2024 |
4,63328 % | MPM BioImpact LLC | 2.654.867 | 701.177 | 30/6/2024 |
3,39961 % | State Street Global Advisors (US) | 1.947.977 | -1.230.450 | 30/6/2024 |
3,26999 % | Vivo Capital, LLC | 1.873.704 | 0 | 30/6/2024 |
2,94053 % | Dimensional Fund Advisors, L.P. | 1.684.924 | -251.233 | 30/6/2024 |
2,80896 % | Candriam Luxembourg S.A. | 1.609.535 | 0 | 30/9/2024 |
1,85009 % | Geode Capital Management, L.L.C. | 1.060.099 | 220.754 | 30/6/2024 |
1,84760 % | Candriam Belgium S.A. | 1.058.673 | 705.655 | 30/6/2024 |
1,74520 % | Polar Capital LLP | 1.000.000 | 250.000 | 30/6/2024 |
1,57986 % | Wellington Management Company, LLP | 905.257 | 69.644 | 30/6/2024 |
1,52410 % | Harmon (Cyrus) | 873.311 | -10.000 | 30/7/2024 |
1,48788 % | Woodline Partners LP | 852.554 | 102.275 | 30/6/2024 |
1,39072 % | Great Point Partners, LLC | 796.880 | 796.880 | 30/6/2024 |
1,35217 % | Victory Capital Management Inc. | 774.792 | 164.143 | 30/6/2024 |
1,13438 % | Boxer Capital, L.L.C. | 650.000 | 650.000 | 30/6/2024 |
1,02792 % | Marshall Wace LLP | 588.996 | 41.193 | 30/6/2024 |
0,98377 % | Myles (David C) | 563.701 | 1.880 | 22/11/2023 |
0,95986 % | Ghost Tree Capital, LLC | 550.000 | 350.000 | 30/6/2024 |
0,95439 % | SilverArc Capital Management, LLC | 546.863 | 31.546 | 30/6/2024 |
0,84640 % | Kovacs Shane William Charles | 484.987 | 10.782 | 23/4/2024 |
0,74021 % | Columbia Threadneedle Investments (US) | 424.141 | 130.976 | 30/6/2024 |
0,67359 % | Rappaport (Andrew) | 385.965 | -95.049 | 23/4/2024 |
0,63085 % | Goldman Sachs & Company, Inc. | 361.479 | 24.078 | 30/6/2024 |
0,58580 % | BlackRock Financial Management, Inc. | 335.665 | 64.979 | 30/6/2024 |
0,56719 % | Adage Capital Management, L.P. | 325.000 | -135.000 | 30/6/2024 |
0,54384 % | Two Sigma Investments, LP | 311.620 | 67.306 | 30/6/2024 |
0,52586 % | Northern Trust Investments, Inc. | 301.317 | -923 | 30/6/2024 |
0,52307 % | Morgan Stanley & Co. LLC | 299.720 | -181.320 | 30/6/2024 |
0,47993 % | Affinity Asset Advisors LLC | 275.000 | 275.000 | 30/6/2024 |
0,43387 % | DWS Investments UK Limited | 248.609 | 4.844 | 30/6/2024 |
0,43260 % | HighVista Strategies LLC | 247.880 | 0 | 30/6/2024 |
0,37784 % | Soleus Capital Management, L.P. | 216.500 | -441.500 | 30/6/2024 |
0,36402 % | AllianceBernstein L.P. | 208.583 | 183.493 | 30/6/2024 |
0,27878 % | Schroder Investment Management Ltd. (SIM) | 159.739 | 159.739 | 30/6/2024 |
0,27683 % | UBS Financial Services, Inc. | 158.625 | -14.536 | 30/6/2024 |
0,25292 % | Bohen (Sean) | 144.925 | 12.621 | 23/4/2024 |
0,24433 % | Newtyn Management, LLC | 140.000 | -10.000 | 30/6/2024 |
0,23280 % | BofA Global Research (US) | 133.395 | -193.424 | 30/6/2024 |
0,23081 % | Citadel Advisors LLC | 132.253 | -648.407 | 30/6/2024 |
0,21500 % | Charles Schwab Investment Management, Inc. | 123.196 | 36.239 | 30/6/2024 |
0,20677 % | Sectoral Asset Management Inc. | 118.480 | -21.500 | 30/6/2024 |
0,20542 % | BlackRock Investment Management, LLC | 117.705 | 41.684 | 30/6/2024 |
0,20523 % | Hennion & Walsh Asset Management, Inc. | 117.595 | 30.283 | 30/9/2024 |
0,20406 % | Schonfeld Strategic Advisors LLC | 116.926 | -86.899 | 30/6/2024 |
0,20199 % | Nuveen LLC | 115.742 | 17.545 | 30/6/2024 |
0,20007 % | Trexquant Investment LP | 114.642 | 114.642 | 30/6/2024 |
0,17802 % | Rafferty Asset Management LLC | 102.006 | -192.713 | 30/6/2024 |
0,16005 % | BNY Mellon Asset Management | 91.707 | 28.666 | 30/6/2024 |
0,15676 % | Zojwalla (Naseem M.D.) | 89.824 | 9.460 | 24/5/2024 |
0,15253 % | Jacobs Levy Equity Management, Inc. | 87.397 | 12.478 | 30/6/2024 |
0,15070 % | Dimensional Fund Advisors, Ltd. | 86.352 | -12.095 | 30/9/2024 |
0,14638 % | Butitta (Cynthia M) | 83.876 | 0 | 23/4/2024 |
0,13852 % | JP Morgan Asset Management | 79.370 | -87 | 31/8/2024 |
0,13029 % | Dana Investment Advisors, Inc. | 74.657 | 74.657 | 30/6/2024 |
0,12518 % | MFS Investment Management | 71.730 | -12.750 | 31/8/2024 |
0,11542 % | Susquehanna International Group, LLP | 66.138 | 18.102 | 30/6/2024 |
0,11518 % | Schweizerische Nationalbank | 66.000 | -4.300 | 30/6/2024 |
0,11021 % | ClariVest Asset Management LLC | 63.149 | 1.881 | 30/6/2024 |
0,10710 % | State of Wisconsin Investment Board | 61.369 | 37.235 | 30/6/2024 |
0,10342 % | Rhumbline Advisers Ltd. Partnership | 59.261 | 17.953 | 30/6/2024 |
0,10173 % | Florida State Board of Administration | 58.290 | -5.100 | 30/6/2024 |
0,09960 % | Squarepoint Capital LLP | 57.070 | -16.519 | 30/6/2024 |
0,09773 % | Janus Henderson Investors | 56.000 | -1.165.662 | 30/6/2024 |
0,09284 % | Renaissance Technologies LLC | 53.200 | 53.200 | 30/6/2024 |
0,09190 % | Jane Street Capital, L.L.C. | 52.661 | 17.007 | 30/6/2024 |
0,08590 % | Envestnet Asset Management, Inc. | 49.220 | 49.220 | 30/6/2024 |
0,08071 % | EP Wealth Advisors, LLC | 46.248 | 0 | 30/6/2024 |
0,07863 % | UBS Asset Management (Switzerland) | 45.055 | 16.265 | 30/6/2024 |
0,07775 % | Barclays Bank PLC | 44.548 | 3.185 | 30/6/2024 |
0,07722 % | BlackRock Advisors (UK) Limited | 44.248 | 700 | 30/9/2024 |
0,07711 % | BlackRock Asset Management Ireland Limited | 44.186 | 1.955 | 30/6/2024 |
0,07618 % | Alps Advisors, Inc. | 43.652 | 4.791 | 30/6/2024 |
0,06916 % | Goldman Sachs Asset Management, L.P. | 39.626 | -60.004 | 30/6/2024 |
0,06780 % | Allianz Global Investors GmbH | 38.850 | 20.830 | 31/8/2024 |
0,06725 % | UBS Fund Management (Switzerland) AG | 38.535 | -8.911 | 30/6/2024 |
0,06669 % | Northern Trust Global Investments | 38.216 | -3.933 | 30/6/2024 |
0,06024 % | Atom Investors LP | 34.515 | -59.806 | 30/6/2024 |
0,05923 % | Mellon Investments Corporation | 33.936 | 15.676 | 30/6/2024 |
0,05810 % | California State Teachers Retirement System | 33.293 | -1.402 | 30/6/2024 |
0,05614 % | Legal & General Investment Management Ltd. | 32.170 | 4.876 | 30/6/2024 |
0,05538 % | Parametric Portfolio Associates LLC | 31.735 | 16.463 | 30/6/2024 |
0,05510 % | Avantis Investors | 31.572 | -3.638 | 31/3/2024 |
0,05492 % | Voya Investment Management LLC | 31.472 | -98.115 | 30/6/2024 |
0,05481 % | Deerfield Management Company, L.P. | 31.405 | 31.405 | 30/6/2024 |
0,05452 % | T. Rowe Price International Ltd | 31.242 | 4.991 | 30/6/2024 |
0,05339 % | Jump Financial, LLC | 30.592 | 30.592 | 30/6/2024 |
0,04916 % | Connor, Clark & Lunn Investment Management Ltd. | 28.167 | -23.755 | 30/6/2024 |
0,04714 % | Pitcairn | 27.013 | 27.013 | 30/6/2024 |
0,04633 % | Susquehanna Portfolio Strategies, LLC | 26.549 | -8.059 | 30/6/2024 |
0,04564 % | Pictet Asset Management Ltd. | 26.154 | 0 | 31/8/2024 |
0,04145 % | Citi Investment Research (US) | 23.752 | -226.230 | 30/6/2024 |
0,04135 % | MetLife Investment Management, LLC | 23.695 | 8.790 | 30/6/2024 |
0,03897 % | Brevan Howard Capital Management LP | 22.328 | 22.328 | 30/6/2024 |
0,03891 % | Assenagon Asset Management S.A. | 22.295 | 342 | 30/9/2024 |