11,22588 % | BlackRock Institutional Trust Company, N.A. | 13 247 666 | 2 057 377 | 30.06.2024 |
9,67466 % | The Vanguard Group, Inc. | 11 417 065 | 1 438 904 | 30.06.2024 |
8,33158 % | Fidelity Management & Research Company LLC | 9 832 098 | 137 240 | 30.06.2024 |
6,89660 % | T. Rowe Price Investment Management, Inc. | 8 138 677 | 3 017 088 | 30.06.2024 |
6,36347 % | Wellington Management Company, LLP | 7 509 530 | 3 528 070 | 30.06.2024 |
5,54914 % | State Street Global Advisors (US) | 6 548 536 | 2 028 178 | 30.06.2024 |
3,87726 % | Darwin Global Management Ltd | 4 575 558 | 4 575 558 | 30.06.2024 |
3,61361 % | BofA Global Research (US) | 4 264 418 | -399 755 | 30.06.2024 |
2,32069 % | Geode Capital Management, L.L.C. | 2 738 646 | 491 481 | 30.06.2024 |
2,30587 % | RTW Investments L.P. | 2 721 158 | 196 078 | 30.06.2024 |
2,08005 % | Polar Capital LLP | 2 454 665 | 849 089 | 30.06.2024 |
1,93857 % | T. Rowe Price Associates, Inc. | 2 287 709 | -585 162 | 30.06.2024 |
1,77951 % | Boxer Capital, L.L.C. | 2 100 000 | 0 | 30.06.2024 |
1,75833 % | Vestal Point Capital, LP | 2 075 000 | -75 000 | 30.06.2024 |
1,75069 % | Armistice Capital LLC | 2 065 991 | 540 303 | 30.06.2024 |
1,59237 % | AllianceBernstein L.P. | 1 879 161 | 109 096 | 30.06.2024 |
1,49832 % | Pictet Asset Management Ltd. | 1 768 162 | 14 516 | 30.06.2024 |
1,48902 % | PFM Health Sciences, LP | 1 757 192 | 0 | 30.06.2024 |
1,43295 % | Fidelity Institutional Asset Management | 1 691 030 | 484 745 | 30.06.2024 |
1,42205 % | Marshall Wace LLP | 1 678 159 | -878 644 | 30.06.2024 |
1,42004 % | Melqart Asset Management (UK) Limited | 1 675 785 | 692 390 | 30.06.2024 |
0,94822 % | Pentwater Capital Management LP | 1 119 000 | 39 000 | 30.06.2024 |
0,94060 % | Sarissa Capital Management, L.P. | 1 110 000 | 810 000 | 30.06.2024 |
0,87934 % | Northern Trust Investments, Inc. | 1 037 704 | 76 490 | 30.06.2024 |
0,84739 % | Integral Health Asset Management, LLC | 1 000 000 | 550 000 | 30.06.2024 |
0,83077 % | RP Management, LLC | 980 392 | 980 392 | 30.06.2024 |
0,82733 % | Janus Henderson Investors | 976 329 | 178 957 | 30.06.2024 |
0,78441 % | Charles Schwab Investment Management, Inc. | 925 682 | 150 126 | 30.06.2024 |
0,74797 % | Morgan Stanley & Co. LLC | 882 675 | 187 204 | 30.06.2024 |
0,74020 % | Westfield Capital Management Company, L.P. | 873 513 | 142 127 | 30.06.2024 |
0,72788 % | Citadel Advisors LLC | 858 973 | 298 071 | 30.06.2024 |
0,72355 % | Adar1 Capital Management LLC | 853 862 | 534 352 | 30.06.2024 |
0,71574 % | JP Morgan Asset Management | 844 650 | 480 894 | 30.06.2024 |
0,68885 % | OrbiMed Advisors, LLC | 812 906 | 130 206 | 30.06.2024 |
0,67762 % | Norges Bank Investment Management (NBIM) | 799 664 | 77 435 | 30.06.2024 |
0,64617 % | Brown Advisory | 762 549 | 3 015 | 30.06.2024 |
0,63049 % | Fidelity Investments Canada ULC | 744 038 | 10 601 | 30.06.2024 |
0,62506 % | Hood River Capital Management LLC | 737 637 | 40 990 | 30.06.2024 |
0,57719 % | Medical Strategy GmbH | 681 145 | -42 471 | 30.06.2024 |
0,57416 % | Goldman Sachs & Company, Inc. | 677 566 | 212 369 | 30.06.2024 |
0,50959 % | Balyasny Asset Management LP | 601 367 | -73 695 | 30.06.2024 |
0,47039 % | Voloridge Investment Management, LLC | 555 110 | -205 209 | 30.06.2024 |
0,46507 % | BlackRock Financial Management, Inc. | 548 824 | 81 175 | 30.06.2024 |
0,45294 % | Fisher Investments | 534 520 | -4 277 | 30.06.2024 |
0,41897 % | Invus Public Equities Advisors, LLC | 494 421 | -12 163 | 30.06.2024 |
0,41597 % | Mellon Investments Corporation | 490 888 | 102 806 | 30.06.2024 |
0,41501 % | Invesco Advisers, Inc. | 489 749 | -765 335 | 30.06.2024 |
0,41141 % | BNY Mellon Asset Management | 485 505 | 69 017 | 30.06.2024 |
0,40183 % | Great Point Partners, LLC | 474 202 | 272 000 | 30.06.2024 |
0,39909 % | Renaissance Technologies LLC | 470 967 | 105 000 | 30.06.2024 |
0,39270 % | Ensign Peak Advisors, Inc. | 463 431 | 39 172 | 30.06.2024 |
0,38640 % | Goldman Sachs Asset Management, L.P. | 455 985 | 248 866 | 30.06.2024 |
0,38451 % | BlackRock Investment Management, LLC | 453 759 | 85 268 | 30.06.2024 |
0,33734 % | Dafna Capital Management, LLC | 398 100 | 0 | 30.06.2024 |
0,33402 % | Readystate Asset Management LP | 394 175 | -71 323 | 30.06.2024 |
0,33351 % | Principal Global Investors (Equity) | 393 579 | -37 977 | 30.06.2024 |
0,32618 % | Sphera Funds Management Ltd. | 384 924 | 103 253 | 30.06.2024 |
0,32138 % | Rhumbline Advisers Ltd. Partnership | 379 257 | 72 618 | 30.06.2024 |
0,31764 % | Point72 Asset Management, L.P. | 374 848 | 10 139 | 30.06.2024 |
0,30557 % | TD Asset Management Inc. | 360 598 | 76 078 | 30.06.2024 |
0,29787 % | BNP Paribas Asset Management USA, Inc. | 351 521 | 25 850 | 30.06.2024 |
0,29494 % | abrdn Inc. | 348 056 | -21 181 | 30.09.2024 |
0,29205 % | Nuveen LLC | 344 644 | -125 943 | 30.06.2024 |
0,28086 % | American Century Investment Management, Inc. | 331 444 | -84 410 | 30.06.2024 |
0,25388 % | UBS Financial Services, Inc. | 299 604 | 860 | 30.06.2024 |
0,24855 % | First Turn Management, LLC | 293 318 | -137 031 | 30.06.2024 |
0,23394 % | MFS Investment Management | 276 067 | 251 389 | 30.06.2024 |
0,23052 % | Saturn V Capital Management LP | 272 036 | 8 335 | 30.06.2024 |
0,22600 % | Kingdon Capital Management, L.L.C. | 266 700 | 150 700 | 30.06.2024 |
0,22462 % | Rafferty Asset Management LLC | 265 069 | 125 592 | 30.06.2024 |
0,22456 % | Jane Street Capital, L.L.C. | 265 002 | -42 565 | 30.06.2024 |
0,21731 % | Finepoint Capital LP | 256 449 | 18 403 | 30.06.2024 |
0,21536 % | Eventide Asset Management, LLC | 254 148 | 0 | 30.06.2024 |
0,21512 % | Pinnacle Associates Ltd. | 253 864 | -3 303 | 30.06.2024 |
0,21480 % | Schroder Investment Management Ltd. (SIM) | 253 487 | 0 | 30.06.2024 |
0,21423 % | Thornburg Investment Management, Inc. | 252 811 | 169 050 | 30.06.2024 |
0,20075 % | Cutter Capital Management, LP | 236 900 | 236 900 | 30.06.2024 |
0,20048 % | BlackRock Advisors (UK) Limited | 236 587 | 4 072 | 30.09.2024 |
0,19490 % | Prosight Capital | 230 000 | -15 000 | 30.06.2024 |
0,19387 % | Blum (Robert I) | 228 785 | 0 | 09.10.2024 |
0,19291 % | Columbia Threadneedle Investments (US) | 227 654 | 69 324 | 30.06.2024 |
0,19240 % | Northern Trust Global Investments | 227 046 | 96 245 | 30.06.2024 |
0,17795 % | Segantii Capital Management Limited | 210 000 | 210 000 | 31.03.2024 |
0,17601 % | BlackRock Asset Management Ireland Limited | 207 712 | 7 365 | 30.06.2024 |
0,17600 % | Clearline Capital LP | 207 695 | 159 660 | 30.06.2024 |
0,17307 % | Corebridge Financial Inc | 204 245 | 204 245 | 30.06.2024 |
0,16998 % | Putnam Investment Management, L.L.C. | 200 598 | -164 512 | 30.06.2024 |
0,16964 % | Franklin Advisers, Inc. | 200 195 | 6 977 | 30.06.2024 |
0,16821 % | Opaleye Management Inc. | 198 500 | 198 500 | 30.06.2024 |
0,16794 % | Woodline Partners LP | 198 181 | 198 181 | 30.06.2024 |
0,16737 % | Rhenman & Partners Asset Management AB | 197 515 | 0 | 30.06.2024 |
0,16609 % | Ghisallo Capital Management LLC | 196 000 | 196 000 | 30.06.2024 |
0,16566 % | Schweizerische Nationalbank | 195 500 | 21 300 | 30.06.2024 |
0,16100 % | Checkpoint Capital L.P. | 190 000 | 0 | 30.06.2024 |
0,15900 % | Superstring Capital Management LP | 187 633 | -91 282 | 30.06.2024 |
0,15231 % | California Public Employees' Retirement System | 179 737 | 48 596 | 30.06.2024 |
0,15185 % | Candriam Luxembourg S.A. | 179 200 | 0 | 30.09.2024 |
0,15185 % | Candriam Belgium S.A. | 179 200 | -313 829 | 30.06.2024 |
0,15107 % | JPMorgan Private Bank (United States) | 178 272 | 38 472 | 30.06.2024 |
0,14920 % | SunAmerica Asset Management, LLC | 176 072 | 125 172 | 31.03.2024 |