7,33082 % | BlackRock Institutional Trust Company, N.A. | 7 690 027 | 1 137 557 | 30.06.2024 |
6,24480 % | Teoxane SA | 6 550 800 | 2 105 000 | 20.10.2023 |
5,96441 % | Franklin Advisers, Inc. | 6 256 664 | 12 872 | 30.06.2024 |
5,69977 % | The Vanguard Group, Inc. | 5 979 062 | 596 053 | 30.06.2024 |
5,01152 % | Palo Alto Investors LP | 5 257 086 | 9 082 | 30.06.2024 |
3,40051 % | Polar Capital LLP | 3 567 139 | -317 680 | 30.06.2024 |
2,66921 % | Stonepine Capital Management, LLC | 2 800 000 | 823 658 | 30.06.2024 |
2,53274 % | Rubric Capital Management LP | 2 656 847 | 0 | 30.06.2024 |
2,19062 % | Geode Capital Management, L.L.C. | 2 297 965 | 327 127 | 30.06.2024 |
2,17697 % | State Street Global Advisors (US) | 2 283 640 | -75 137 | 30.06.2024 |
2,14236 % | JP Morgan Asset Management | 2 247 339 | -109 526 | 30.06.2024 |
2,13299 % | Federated MDTA LLC | 2 237 505 | 755 803 | 30.06.2024 |
1,58236 % | Water Island Capital, LLC | 1 659 892 | 10 000 | 30.09.2024 |
1,56573 % | Beryl Capital Management, LLC | 1 642 448 | 1 642 448 | 05.09.2024 |
1,05515 % | Foley (Mark J) | 1 106 848 | 1 000 | 30.06.2024 |
0,99195 % | Nuveen LLC | 1 040 555 | 696 030 | 30.06.2024 |
0,97585 % | Baron Capital Management, Inc. | 1 023 663 | 0 | 30.06.2024 |
0,72724 % | Northern Trust Investments, Inc. | 762 874 | 4 188 | 30.06.2024 |
0,72156 % | Millennium Management LLC | 756 912 | 604 547 | 30.06.2024 |
0,71457 % | Charles Schwab Investment Management, Inc. | 749 587 | 49 537 | 30.06.2024 |
0,70476 % | Morgan Stanley & Co. LLC | 739 297 | -225 757 | 30.06.2024 |
0,69608 % | Rice Hall James & Associates, LLC | 730 190 | 18 118 | 30.09.2024 |
0,66893 % | Rhenman & Partners Asset Management AB | 701 707 | 0 | 30.06.2024 |
0,61411 % | Two Sigma Investments, LP | 644 203 | 386 806 | 30.06.2024 |
0,58226 % | Walleye Capital LLC | 610 792 | -11 334 | 30.06.2024 |
0,57975 % | Goldman Sachs & Company, Inc. | 608 160 | 197 141 | 30.06.2024 |
0,57197 % | Perceptive Advisors LLC | 600 000 | 0 | 30.06.2024 |
0,54528 % | Renaissance Technologies LLC | 572 000 | 198 300 | 30.06.2024 |
0,51038 % | Hightower Advisors, LLC | 535 387 | 90 000 | 30.06.2024 |
0,47664 % | Integral Health Asset Management, LLC | 500 000 | 500 000 | 30.06.2024 |
0,47664 % | EULAV Asset Management | 500 000 | 0 | 30.06.2024 |
0,43573 % | EW Healthcare Partners | 457 085 | 0 | 30.06.2024 |
0,43207 % | Alpine Associates Management Inc. | 453 243 | -5 957 | 30.09.2024 |
0,42096 % | ExodusPoint Capital Management, LP | 441 584 | 441 584 | 30.06.2024 |
0,39767 % | Graham Capital Management, L.P. | 417 161 | 417 161 | 30.06.2024 |
0,38132 % | CM Management, LLC | 400 000 | 150 000 | 30.06.2024 |
0,38132 % | Tang Capital Management, LLC | 400 000 | 200 000 | 30.06.2024 |
0,32673 % | J.P. Morgan Securities LLC | 342 744 | -87 173 | 30.06.2024 |
0,31012 % | UBS O'Connor LLC | 325 314 | 70 647 | 30.06.2024 |
0,30441 % | Lane Generational, LLC | 319 322 | 319 322 | 30.06.2024 |
0,28384 % | Goldman Sachs Asset Management, L.P. | 297 744 | 165 314 | 30.06.2024 |
0,27694 % | William Blair & Company, L.L.C. (Research) | 290 515 | -38 752 | 30.06.2024 |
0,27524 % | International Biotechnology Trust PLC | 288 726 | 0 | 30.09.2023 |
0,27451 % | BlackRock Investment Management, LLC | 287 961 | 78 202 | 30.06.2024 |
0,27078 % | BlackRock Financial Management, Inc. | 284 053 | 46 179 | 30.06.2024 |
0,23869 % | JPMorgan Asset Management U.K. Limited | 250 388 | -18 027 | 30.06.2024 |
0,23832 % | DCF Advisers, LLC | 250 000 | -13 372 | 30.06.2024 |
0,23832 % | Moore Capital Management, LP | 250 000 | 0 | 30.06.2024 |
0,23740 % | Citadel Advisors LLC | 249 029 | 198 366 | 30.06.2024 |
0,23356 % | AlphaCentric Advisors LLC. | 245 000 | 0 | 30.09.2024 |
0,23356 % | LifeSci Fund Management LLC | 245 000 | 0 | 30.06.2024 |
0,22908 % | BNY Mellon Asset Management | 240 300 | 49 873 | 30.06.2024 |
0,21449 % | Ghost Tree Capital, LLC | 225 000 | -225 000 | 30.06.2024 |
0,19976 % | BlackRock Asset Management Ireland Limited | 209 545 | 48 030 | 30.06.2024 |
0,19169 % | AQR Capital Management, LLC | 201 080 | 170 960 | 30.06.2024 |
0,18784 % | PDT Partners, LLC | 197 049 | 197 049 | 30.06.2024 |
0,18556 % | Schweizerische Nationalbank | 194 650 | 0 | 30.06.2024 |
0,18462 % | Schilke (Tobin C) | 193 666 | 1 000 | 30.06.2024 |
0,18455 % | Schonfeld Strategic Advisors LLC | 193 591 | 193 591 | 30.06.2024 |
0,18357 % | BlackRock Advisors (UK) Limited | 192 565 | 2 094 | 30.09.2024 |
0,17493 % | FNY Investment Advisers LLC | 183 500 | 183 500 | 30.09.2024 |
0,17155 % | BofA Global Research (US) | 179 951 | -324 725 | 30.06.2024 |
0,16871 % | Susquehanna International Group, LLP | 176 973 | 57 064 | 30.06.2024 |
0,16010 % | Columbia Threadneedle Investments (US) | 167 948 | -1 963 | 30.06.2024 |
0,15972 % | Sjuts (Dustin S) | 167 550 | 40 217 | 18.03.2024 |
0,15904 % | Fidelity Management & Research Company LLC | 166 828 | 159 200 | 30.06.2024 |
0,15626 % | Jane Street Capital, L.L.C. | 163 913 | 24 012 | 30.06.2024 |
0,15348 % | Norges Bank Investment Management (NBIM) | 161 000 | 0 | 30.06.2024 |
0,15331 % | Conestoga Capital Advisors, LLC | 160 821 | -1 547 | 31.03.2024 |
0,13762 % | Nebula Research & Development LLC | 144 365 | -30 502 | 30.06.2024 |
0,13466 % | Centiva Capital, LP | 141 259 | 126 259 | 30.06.2024 |
0,13444 % | Morgan Stanley Smith Barney LLC | 141 027 | 20 184 | 30.06.2024 |
0,13138 % | Moxie (Dwight) | 137 815 | 30 955 | 18.03.2024 |
0,13117 % | IndexIQ Advisors LLC | 137 594 | 137 594 | 30.09.2024 |
0,12998 % | Rhumbline Advisers Ltd. Partnership | 136 347 | 14 191 | 30.06.2024 |
0,11976 % | UBS Fund Management (Switzerland) AG | 125 627 | -54 521 | 30.06.2024 |
0,11508 % | AllianceBernstein L.P. | 120 720 | 30 220 | 30.06.2024 |
0,11093 % | Los Angeles Capital Management LLC | 116 368 | 23 450 | 30.06.2024 |
0,10991 % | BNP Paribas Securities Corp. North America | 115 291 | -96 404 | 30.06.2024 |
0,10950 % | Jordan (Erica) | 114 864 | -2 392 | 16.04.2024 |
0,10377 % | Hollander (David) | 108 853 | 0 | 08.03.2024 |
0,10294 % | D. E. Shaw & Co., L.P. | 107 980 | -190 130 | 30.06.2024 |
0,09951 % | JPMorgan Private Bank (United States) | 104 390 | 6 464 | 30.06.2024 |
0,09344 % | Mellon Investments Corporation | 98 021 | 31 137 | 30.06.2024 |
0,09278 % | California State Teachers Retirement System | 97 324 | -169 | 30.06.2024 |
0,09079 % | UBS Asset Management (Switzerland) | 95 234 | 15 033 | 30.06.2024 |
0,09005 % | Parametric Portfolio Associates LLC | 94 467 | -21 834 | 30.06.2024 |
0,09004 % | T. Rowe Price International Ltd | 94 453 | 25 092 | 30.06.2024 |
0,08801 % | Parallel Advisors, LLC | 92 323 | 92 323 | 30.06.2024 |
0,08608 % | PenderFund Capital Management, Ltd. | 90 300 | 90 300 | 31.08.2024 |
0,08427 % | Summit Wealth Strategies | 88 395 | 54 961 | 30.06.2024 |
0,08208 % | Deka Verm¿gensmanagement GmbH | 86 100 | 0 | 30.09.2024 |
0,08208 % | Deka Investment GmbH | 86 100 | 0 | 31.12.2023 |
0,07883 % | Tejara Capital Ltd. | 82 688 | -87 312 | 30.06.2024 |
0,07777 % | Jacobs Levy Equity Management, Inc. | 81 579 | 81 579 | 30.06.2024 |
0,07441 % | Inspire Investing | 78 055 | -61 024 | 30.09.2024 |
0,07440 % | Commonwealth Financial Network | 78 041 | -31 876 | 30.09.2024 |
0,07337 % | SG Americas Securities, L.L.C. | 76 963 | 76 963 | 30.09.2024 |
0,06787 % | Legal & General Investment Management Ltd. | 71 199 | -11 973 | 30.06.2024 |
0,06666 % | XTX Markets LLC | 69 926 | 15 267 | 30.06.2024 |