6,29399 % | BlackRock Institutional Trust Company, N.A. | 6 614 350 | 419 633 | 2023-12-31 |
5,47056 % | Millennium Management LLC | 5 749 015 | 736 732 | 2024-03-19 |
5,37149 % | Cadian Capital Management LP | 5 644 898 | 5 644 898 | 2023-12-31 |
5,01466 % | The Vanguard Group, Inc. | 5 269 902 | 243 261 | 2023-12-31 |
4,79908 % | Vitruvian Partners LLP | 5 043 356 | 0 | 2023-12-31 |
4,38738 % | Sofinnova Partners | 4 610 693 | −365 803 | 2022-12-31 |
2,78383 % | Morgan Stanley Investment Management Inc. (US) | 2 925 528 | 2 012 145 | 2023-12-31 |
2,62370 % | Portolan Capital Management, L.L.C. | 2 757 249 | 613 583 | 2023-12-31 |
2,49238 % | Fidelity Management & Research Company LLC | 2 619 243 | 2 616 840 | 2023-12-31 |
2,41423 % | MFS Investment Management | 2 537 114 | 584 372 | 2023-12-31 |
1,99495 % | Geode Capital Management, L.L.C. | 2 096 497 | 123 060 | 2023-12-31 |
1,84984 % | State Street Global Advisors (US) | 1 943 997 | 103 823 | 2023-12-31 |
1,79370 % | Blue Water Life Science Advisors, LP. | 1 885 000 | 0 | 2023-12-31 |
1,79023 % | Mudita Advisors LLP | 1 881 349 | 490 491 | 2023-12-31 |
1,66524 % | Canaccord Genuity Wealth Management | 1 750 000 | 0 | 2023-12-31 |
1,52250 % | Swedbank Robur Fonder AB | 1 600 000 | 0 | 2024-02-29 |
1,44509 % | River Global Investors LLP | 1 518 646 | 45 392 | 2023-12-31 |
1,35926 % | Granahan Investment Management, LLC | 1 428 449 | −547 398 | 2023-12-31 |
1,30724 % | ArrowMark Colorado Holdings, LLC | 1 373 777 | −1 035 261 | 2023-12-31 |
1,25676 % | Berenberg Bank (Asset Management) | 1 320 732 | −54 500 | 2023-04-30 |
1,22842 % | Columbia Threadneedle Investments (US) | 1 290 949 | 138 080 | 2023-12-31 |
0,97060 % | Chelverton Asset Management Ltd. | 1 020 000 | −30 000 | 2023-12-31 |
0,69810 % | Northern Trust Investments, Inc. | 733 632 | 19 568 | 2023-12-31 |
0,66130 % | Dimensional Fund Advisors, L.P. | 694 961 | 218 356 | 2023-12-31 |
0,63648 % | Silvercrest Asset Management Group LLC | 668 880 | −591 743 | 2023-12-31 |
0,62510 % | Grandeur Peak Global Advisors, LLC | 656 916 | −777 903 | 2023-12-31 |
0,56220 % | Crux Asset Management Limited | 590 820 | −28 000 | 2024-02-29 |
0,52336 % | Willis Investment Counsel Inc. | 550 000 | 550 000 | 2023-12-31 |
0,45184 % | Octopus Investments Limited | 474 835 | −70 000 | 2024-02-29 |
0,43007 % | North Run Capital, LP | 451 960 | −105 000 | 2022-12-31 |
0,42820 % | AWM Investment Company, Inc. | 450 000 | 450 000 | 2023-12-31 |
0,42428 % | Morgan Stanley & Co. LLC | 445 871 | 223 174 | 2023-12-31 |
0,38738 % | Fred Alger Management, LLC | 407 096 | 46 222 | 2023-12-31 |
0,36750 % | Roubaix Capital, LLC | 386 201 | 386 201 | 2023-12-31 |
0,35635 % | Mandell (Arthur M) | 374 484 | 0 | 2023-03-31 |
0,34935 % | Lazard Asset Management, L.L.C. | 367 132 | −90 236 | 2023-12-31 |
0,31706 % | Doerfler (Douglas A.) | 333 197 | 0 | 2023-12-05 |
0,31148 % | Royce Investment Partners | 327 338 | −95 222 | 2023-12-31 |
0,29307 % | Apollo Capital Management, L.P. | 307 987 | 0 | 2023-12-31 |
0,28641 % | Rathbones Investment Management Limited | 300 988 | −2 730 | 2023-12-31 |
0,27134 % | Allspring Global Investments, LLC | 285 146 | −5 406 | 2024-03-31 |
0,25363 % | BNY Mellon Asset Management | 266 538 | 42 459 | 2023-12-31 |
0,25247 % | BlackRock Financial Management, Inc. | 265 320 | 2 233 | 2023-12-31 |
0,24223 % | William Blair & Company, L.L.C. (Research) | 254 563 | 2 712 | 2023-12-31 |
0,23884 % | Jacobs Levy Equity Management, Inc. | 251 001 | 251 001 | 2023-12-31 |
0,23789 % | Bleichroeder LP | 250 000 | 0 | 2023-12-31 |
0,23654 % | BlackRock Investment Management, LLC | 248 581 | −6 763 | 2023-12-31 |
0,23575 % | Erck (Stanley C) | 247 751 | 0 | 2023-03-31 |
0,23376 % | Nuveen LLC | 245 655 | 0 | 2023-12-31 |
0,23194 % | Charles Schwab Investment Management, Inc. | 243 743 | 5 271 | 2023-12-31 |
0,20408 % | Fidelity Institutional Asset Management | 214 472 | 214 472 | 2023-12-31 |
0,18210 % | ARIAD Asset Management GmbH | 191 370 | 0 | 2024-01-31 |
0,17994 % | Renaissance Technologies LLC | 189 100 | −22 000 | 2023-12-31 |
0,16867 % | JPMorgan Private Bank (United States) | 177 259 | 123 676 | 2023-12-31 |
0,16639 % | Two Sigma Investments, LP | 174 860 | 174 860 | 2023-12-31 |
0,16510 % | Schweizerische Nationalbank | 173 500 | −16 900 | 2023-12-31 |
0,14037 % | BlackRock Advisors (UK) Limited | 147 520 | 4 849 | 2024-03-31 |
0,13821 % | BofA Global Research (US) | 145 249 | 64 352 | 2023-12-31 |
0,13697 % | Conestoga Capital Advisors, LLC | 143 945 | 0 | 2024-02-29 |
0,13481 % | UBS Asset Management (Americas), Inc. | 141 676 | 0 | 2023-03-31 |
0,13322 % | Toscafund Asset Management LLP | 140 000 | 0 | 2023-06-30 |
0,13080 % | Barclays Bank PLC | 137 460 | 106 266 | 2023-12-31 |
0,12954 % | Alberta Investment Management Corporation | 136 135 | −63 688 | 2023-12-31 |
0,12851 % | Citadel Advisors LLC | 135 055 | 86 981 | 2023-12-31 |
0,12642 % | Rhumbline Advisers Ltd. Partnership | 132 851 | 1 443 | 2023-12-31 |
0,12347 % | Goldman Sachs Asset Management, L.P. | 129 755 | 33 694 | 2023-12-31 |
0,12299 % | BlackRock Asset Management Ireland Limited | 129 250 | 8 896 | 2023-12-31 |
0,11474 % | Johnston (John Joseph) | 120 583 | 0 | 2024-03-26 |
0,10971 % | Mellon Investments Corporation | 115 295 | 0 | 2023-12-31 |
0,10948 % | Avantis Investors | 115 055 | 46 070 | 2024-03-31 |
0,10933 % | State Teachers Retirement System of Ohio | 114 900 | −6 300 | 2023-12-31 |
0,10598 % | Squarepoint Capital LLP | 111 375 | 111 375 | 2023-12-31 |
0,10430 % | Parametric Portfolio Associates LLC | 109 611 | −79 248 | 2023-12-31 |
0,09516 % | Lauxera Capital Partners | 100 000 | 0 | 2024-01-31 |
0,09516 % | Douglas (Richard H) | 100 000 | 80 000 | 2023-03-31 |
0,09094 % | UBS Financial Services, Inc. | 95 574 | 30 643 | 2023-12-31 |
0,08820 % | California State Teachers Retirement System | 92 693 | −4 004 | 2023-12-31 |
0,08764 % | UBS Asset Management (UK) Ltd. | 92 100 | 0 | 2023-12-31 |
0,08632 % | Columbia Threadneedle Management Limited | 90 718 | 1 147 | 2023-12-31 |
0,08308 % | Wilmington Trust Investment Advisors, Inc. | 87 304 | −76 058 | 2023-12-31 |
0,08006 % | American Century Investment Management, Inc. | 84 136 | −1 621 992 | 2023-12-31 |
0,07986 % | ValMark Advisers, Inc. | 83 927 | 83 927 | 2023-12-31 |
0,07731 % | Swirsky (Douglas J) | 81 250 | 81 250 | 2024-03-15 |
0,07701 % | Credit Suisse Funds AG | 80 934 | 11 573 | 2023-12-31 |
0,07691 % | Legal & General Investment Management Ltd. | 80 822 | 6 718 | 2023-12-31 |
0,06990 % | SEI Investments Management Corporation | 73 460 | −1 488 | 2023-12-31 |
0,06760 % | Assenagon Asset Management S.A. | 71 038 | 5 145 | 2024-02-29 |
0,06683 % | Citi Investment Research (US) | 70 228 | 11 170 | 2023-12-31 |
0,06594 % | Ohio Public Employees Retirement System | 69 300 | 69 300 | 2023-12-31 |
0,06534 % | Jane Street Capital, L.L.C. | 68 662 | 51 983 | 2023-12-31 |
0,06440 % | Goldman Sachs & Company, Inc. | 67 673 | −4 731 | 2023-12-31 |
0,06003 % | AllianceBernstein L.P. | 63 090 | −4 530 | 2023-12-31 |
0,05899 % | Ensign Peak Advisors, Inc. | 61 990 | 3 600 | 2023-12-31 |
0,05708 % | Aperio Group, LLC | 59 983 | 40 786 | 2023-12-31 |
0,05580 % | Northern Trust Global Investments | 58 645 | −764 | 2023-12-31 |
0,05473 % | Susquehanna International Group, LLP | 57 521 | 38 251 | 2023-12-31 |
0,05443 % | State Street Global Advisors Ireland Limited | 57 204 | −208 | 2023-04-30 |
0,05404 % | Chevy Chase Trust Company | 56 795 | 543 | 2023-12-31 |
0,05395 % | Gagnon Securities LLC | 56 701 | 1 264 | 2023-12-31 |
0,05364 % | Salem Investment Counselors, Inc. | 56 375 | 28 741 | 2024-03-31 |