8,59336 % | The Vanguard Group, Inc. | 14.354.342 | -381.474 | 30. 6. 2024. |
8,17780 % | Wellington Management Company, LLP | 13.660.196 | -1.054.530 | 30. 6. 2024. |
6,52702 % | BlackRock Institutional Trust Company, N.A. | 10.902.738 | 779.058 | 30. 6. 2024. |
5,84153 % | Farallon Capital Management, L.L.C. | 9.757.692 | 2.249.820 | 30. 6. 2024. |
4,53130 % | Baker Bros. Advisors LP | 7.569.090 | 19.841 | 30. 6. 2024. |
3,76960 % | Nextech Invest, Ltd. | 6.296.740 | 0 | 30. 6. 2024. |
3,58071 % | BVF Partners L.P. | 5.981.212 | 0 | 30. 6. 2024. |
3,36748 % | Fidelity Management & Research Company LLC | 5.625.035 | 1.458.597 | 30. 6. 2024. |
3,17713 % | Alphabet, Inc. | 5.307.075 | 5.563 | 30. 6. 2024. |
3,14840 % | Paradigm BioCapital Advisors LP | 5.259.089 | 2.344.114 | 30. 6. 2024. |
3,03584 % | State Street Global Advisors (US) | 5.071.068 | -314.952 | 30. 6. 2024. |
3,03077 % | T. Rowe Price Associates, Inc. | 5.062.599 | 391.615 | 30. 6. 2024. |
3,01072 % | Bellevue Asset Management AG | 5.029.100 | -44.500 | 30. 6. 2024. |
2,77791 % | Janus Henderson Investors | 4.640.218 | 728.099 | 30. 6. 2024. |
2,63822 % | Casdin Capital, LLC | 4.406.875 | -1.210.724 | 30. 6. 2024. |
2,56194 % | Boxer Capital, L.L.C. | 4.279.464 | 0 | 30. 6. 2024. |
1,99692 % | Geode Capital Management, L.L.C. | 3.335.656 | 282.965 | 30. 6. 2024. |
1,97006 % | Woodline Partners LP | 3.290.791 | -506.357 | 30. 6. 2024. |
1,84990 % | Deerfield Management Company, L.P. | 3.090.073 | 0 | 30. 6. 2024. |
1,64543 % | Andreessen Horowitz | 2.748.523 | 0 | 30. 6. 2024. |
1,41498 % | Balyasny Asset Management LP | 2.363.584 | 708.689 | 30. 6. 2024. |
1,39520 % | Borisy (Alexis) | 2.330.542 | 4.248 | 20. 6. 2024. |
1,33159 % | JP Morgan Asset Management | 2.224.283 | -182.612 | 30. 6. 2024. |
1,31913 % | Holocene Advisors, LP | 2.203.474 | -218.937 | 30. 6. 2024. |
1,10671 % | Norges Bank Investment Management (NBIM) | 1.848.647 | 1.566.942 | 30. 6. 2024. |
0,99648 % | Lord, Abbett & Co. LLC | 1.664.516 | -13.315 | 31. 8. 2024. |
0,71839 % | Logos Global Management LLC | 1.200.000 | 1.200.000 | 30. 6. 2024. |
0,68419 % | BlackRock Financial Management, Inc. | 1.142.863 | 79.755 | 30. 6. 2024. |
0,66432 % | Charles Schwab Investment Management, Inc. | 1.109.684 | 57.421 | 30. 6. 2024. |
0,64180 % | Northern Trust Investments, Inc. | 1.072.055 | -37.405 | 30. 6. 2024. |
0,61960 % | Goldman Sachs & Company, Inc. | 1.034.972 | 334.291 | 30. 6. 2024. |
0,60810 % | Invus Public Equities Advisors, LLC | 1.015.776 | -302.873 | 30. 6. 2024. |
0,59714 % | Frazier Life Sciences Management, L.P. | 997.455 | 0 | 30. 6. 2024. |
0,56465 % | Rock Springs Capital Management LP | 943.195 | 19.514 | 30. 6. 2024. |
0,54718 % | Hood River Capital Management LLC | 914.003 | 914.003 | 30. 6. 2024. |
0,51256 % | Soleus Capital Management, L.P. | 856.178 | 127.478 | 30. 6. 2024. |
0,50856 % | Morgan Stanley & Co. LLC | 849.505 | 6.716 | 30. 6. 2024. |
0,48854 % | Marshall Wace LLP | 816.055 | -719.885 | 30. 6. 2024. |
0,45199 % | Avidity Partners Management LP | 755.000 | 120.000 | 30. 6. 2024. |
0,43670 % | Finepoint Capital LP | 729.464 | 52.364 | 30. 6. 2024. |
0,39665 % | Candriam Luxembourg S.A. | 662.564 | 0 | 30. 9. 2024. |
0,38962 % | Eventide Asset Management, LLC | 650.826 | 289.826 | 30. 6. 2024. |
0,38034 % | Columbia Threadneedle Investments (UK) | 635.319 | -245.391 | 30. 6. 2024. |
0,37222 % | JPMorgan Asset Management U.K. Limited | 621.752 | -218.680 | 30. 6. 2024. |
0,35657 % | Goldsmith Mark A | 595.609 | 0 | 11. 10. 2024. |
0,33186 % | Candriam Belgium S.A. | 554.334 | -29.616 | 30. 6. 2024. |
0,32483 % | Victory Capital Management Inc. | 542.601 | -57.980 | 30. 6. 2024. |
0,32339 % | Pzena Investment Management, LLC | 540.194 | -160.971 | 30. 6. 2024. |
0,31089 % | American Century Investment Management, Inc. | 519.305 | 519.305 | 30. 6. 2024. |
0,30645 % | Dafna Capital Management, LLC | 511.894 | 0 | 30. 6. 2024. |
0,30446 % | MIC Capital Management UK LLP | 508.569 | 0 | 30. 6. 2024. |
0,29746 % | Columbia Threadneedle Investments (US) | 496.878 | 49.167 | 30. 6. 2024. |
0,28908 % | BlackRock Advisors (UK) Limited | 482.883 | 617 | 30. 9. 2024. |
0,27245 % | Sofinnova Investments, Inc | 455.099 | 455.099 | 30. 6. 2024. |
0,27052 % | BlackRock Asset Management Ireland Limited | 451.870 | 115.991 | 30. 6. 2024. |
0,25154 % | BlackRock Investment Management, LLC | 420.169 | 59.350 | 30. 6. 2024. |
0,24532 % | Nuveen LLC | 409.781 | 45.858 | 30. 6. 2024. |
0,24476 % | Citadel Advisors LLC | 408.842 | -179.246 | 30. 6. 2024. |
0,23916 % | Goldman Sachs Asset Management, L.P. | 399.489 | -13.221 | 30. 6. 2024. |
0,23434 % | BlackRock Investment Management (UK) Ltd. | 391.439 | 44.624 | 30. 6. 2024. |
0,23383 % | Dimensional Fund Advisors, L.P. | 390.583 | -940.676 | 30. 6. 2024. |
0,22811 % | BofA Global Research (US) | 381.041 | -140.355 | 30. 6. 2024. |
0,22785 % | Jane Street Capital, L.L.C. | 380.594 | 251.127 | 30. 6. 2024. |
0,21696 % | BNY Mellon Asset Management | 362.416 | 46.589 | 30. 6. 2024. |
0,20246 % | Partners HealthCare System, Inc | 338.191 | 0 | 30. 9. 2024. |
0,19727 % | First Turn Management, LLC | 329.519 | 329.519 | 30. 6. 2024. |
0,19456 % | Integral Health Asset Management, LLC | 325.000 | -95.000 | 30. 6. 2024. |
0,19134 % | AllianceBernstein L.P. | 319.618 | -3.746 | 30. 6. 2024. |
0,18402 % | Columbia Wanger Asset Management, LLC | 307.387 | 0 | 30. 6. 2024. |
0,17325 % | MPM BioImpact LLC | 289.396 | 16.179 | 30. 6. 2024. |
0,16927 % | AHL Partners LLP | 282.746 | 253.449 | 30. 6. 2024. |
0,16643 % | Mubadala Investment Company PJSC | 278.000 | 0 | 30. 6. 2024. |
0,16134 % | Ensign Peak Advisors, Inc. | 269.504 | 229.721 | 30. 6. 2024. |
0,16102 % | Mellon Investments Corporation | 268.962 | 65.210 | 30. 6. 2024. |
0,15749 % | Voya Investment Management LLC | 263.079 | -20.554 | 30. 6. 2024. |
0,14978 % | TD Asset Management Inc. | 250.194 | -4.400 | 30. 6. 2024. |
0,14918 % | Qube Research & Technologies Ltd | 249.188 | 81.708 | 30. 6. 2024. |
0,14574 % | Bessemer Trust Company, N.A. (US) | 243.442 | 0 | 30. 6. 2024. |
0,13683 % | Rhumbline Advisers Ltd. Partnership | 228.567 | 19.257 | 30. 6. 2024. |
0,13680 % | Susquehanna Fundamental Investments, LLC | 228.513 | 22.000 | 30. 6. 2024. |
0,13645 % | Point72 Asset Management, L.P. | 227.922 | 227.922 | 30. 6. 2024. |
0,13611 % | HSBC Private Bank (Suisse) S.A. | 227.365 | 19.081 | 31. 8. 2024. |
0,13579 % | Schweizerische Nationalbank | 226.831 | 26.700 | 30. 6. 2024. |
0,13419 % | Walleye Capital LLC | 224.143 | 189.186 | 30. 6. 2024. |
0,13188 % | TwinBeech Capital LP | 220.289 | 220.289 | 30. 6. 2024. |
0,13037 % | UBS Financial Services, Inc. | 217.763 | -87.216 | 30. 6. 2024. |
0,12714 % | Manulife Investment Management (North America) Limited | 212.368 | 13.318 | 30. 6. 2024. |
0,11405 % | Raymond James & Associates, Inc. | 190.505 | 116.135 | 30. 9. 2024. |
0,11113 % | Rafferty Asset Management LLC | 185.637 | -98.715 | 30. 6. 2024. |
0,10177 % | Adage Capital Management, L.P. | 170.000 | -30.000 | 30. 6. 2024. |
0,09773 % | Readystate Asset Management LP | 163.241 | 95.941 | 30. 6. 2024. |
0,09479 % | Kelsey (Stephen Michael) | 158.345 | 0 | 14. 10. 2024. |
0,09467 % | Nicholas Investment Partners, L.P. | 158.132 | 142.044 | 30. 6. 2024. |
0,09223 % | T. Rowe Price International Ltd | 154.060 | 10.734 | 30. 6. 2024. |
0,08506 % | Neuberger Berman, LLC | 142.087 | -1.272 | 30. 6. 2024. |
0,08235 % | JPMorgan Private Bank (United States) | 137.559 | -1.373 | 30. 6. 2024. |
0,08065 % | Conestoga Capital Advisors, LLC | 134.721 | -1.296 | 31. 3. 2024. |
0,07962 % | Acuta Capital Partners, LLC | 133.000 | -10.777 | 30. 6. 2024. |
0,07899 % | J.P. Morgan Securities plc | 131.944 | 95.918 | 30. 6. 2024. |
0,07826 % | Legal & General Investment Management Ltd. | 130.725 | 24.596 | 30. 6. 2024. |