18,39197 % | VenBio Partners LLC | 9.699.925 | 0 | 31. 12. 2024. |
6,99585 % | Redmile Group, LLC | 3.689.611 | -146.965 | 31. 12. 2024. |
6,49778 % | HBM Partners AG | 3.426.929 | 3.426.929 | 18. 12. 2024. |
6,25120 % | Tang Capital Management, LLC | 3.296.883 | -907.852 | 31. 12. 2024. |
5,59268 % | Lightstone Ventures, L.P. | 2.949.580 | -1.259.395 | 12. 2. 2024. |
4,25091 % | Morgan Stanley & Co. LLC | 2.241.932 | 1.996.515 | 31. 12. 2024. |
4,12101 % | BlackRock Institutional Trust Company, N.A. | 2.173.423 | -180.204 | 31. 12. 2024. |
4,03699 % | Millennium Management LLC | 2.129.110 | 126.736 | 31. 12. 2024. |
3,57793 % | The Vanguard Group, Inc. | 1.887.002 | 2.429 | 31. 12. 2024. |
3,17381 % | Fidelity Management & Research Company LLC | 1.673.866 | -4.188.215 | 31. 12. 2024. |
2,89729 % | Two Sigma Investments, LP | 1.528.031 | 367.472 | 31. 12. 2024. |
2,63829 % | MPM BioImpact LLC | 1.391.434 | -1.018.428 | 31. 12. 2024. |
2,31882 % | Almitas Capital LLC | 1.222.945 | 1.222.945 | 31. 12. 2024. |
2,10362 % | Acadian Asset Management LLC | 1.109.448 | 683.024 | 31. 12. 2024. |
1,96308 % | BofA Global Research (US) | 1.035.326 | 860.703 | 31. 12. 2024. |
1,40331 % | Geode Capital Management, L.L.C. | 740.106 | 39.259 | 31. 12. 2024. |
1,29716 % | State Street Global Advisors (US) | 684.123 | 12.747 | 31. 12. 2024. |
1,15542 % | BMO Capital Markets (US) | 609.368 | 609.368 | 31. 12. 2024. |
0,96522 % | Privium Fund Management BV | 509.059 | 0 | 31. 12. 2024. |
0,80885 % | Pons (Jaume) | 426.589 | -10.796 | 30. 12. 2024. |
0,77371 % | UBS Financial Services, Inc. | 408.056 | 378.816 | 31. 12. 2024. |
0,68354 % | Goldman Sachs & Company, Inc. | 360.498 | 208.278 | 31. 12. 2024. |
0,65040 % | Northern Trust Investments, Inc. | 343.020 | 63.853 | 31. 12. 2024. |
0,57152 % | Los Angeles Capital Management LLC | 301.419 | 43.640 | 31. 12. 2024. |
0,50030 % | XTX Markets LLC | 263.856 | -53.466 | 31. 12. 2024. |
0,48517 % | D. E. Shaw & Co., L.P. | 255.878 | -34.518 | 31. 12. 2024. |
0,47820 % | Parametric Portfolio Associates LLC | 252.201 | 182.066 | 31. 12. 2024. |
0,46044 % | Randolph (Sophia) | 242.836 | -1.365 | 14. 8. 2024. |
0,41186 % | BMO Family Office, LLC | 217.214 | 217.214 | 31. 12. 2024. |
0,41090 % | Charles Schwab Investment Management, Inc. | 216.707 | -8.595 | 31. 12. 2024. |
0,40782 % | J.P. Morgan Securities LLC | 215.085 | 194.983 | 31. 12. 2024. |
0,39536 % | Goldman Sachs Asset Management, L.P. | 208.511 | 126.656 | 31. 12. 2024. |
0,37482 % | Diadema Partners LP | 197.680 | 197.680 | 31. 12. 2024. |
0,33692 % | Fidelity Institutional Asset Management | 177.690 | 174.665 | 31. 12. 2024. |
0,31735 % | Goodman (Corey S) | 167.370 | 0 | 31. 3. 2024. |
0,28749 % | Susquehanna International Group, LLP | 151.620 | 121.272 | 31. 12. 2024. |
0,26255 % | Qube Research & Technologies Ltd | 138.470 | -319.247 | 31. 12. 2024. |
0,21886 % | BlackRock Financial Management, Inc. | 115.429 | -2.241 | 31. 12. 2024. |
0,20749 % | Lettmann (Jason) | 109.429 | -2.191 | 14. 8. 2024. |
0,19967 % | Bank of Nova Scotia | 105.306 | 105.306 | 31. 12. 2024. |
0,19718 % | Nuveen LLC | 103.995 | 0 | 31. 12. 2024. |
0,19013 % | DWS Investments UK Limited | 100.276 | 84.830 | 31. 12. 2024. |
0,17747 % | BlackRock Investment Management, LLC | 93.597 | 0 | 31. 12. 2024. |
0,14221 % | Bridgeway Capital Management, LLC | 75.000 | 75.000 | 31. 12. 2024. |
0,13601 % | AllianceBernstein L.P. | 71.730 | 0 | 31. 12. 2024. |
0,13145 % | BNY Mellon Asset Management | 69.327 | 9.623 | 31. 12. 2024. |
0,12554 % | abrdn Inc. | 66.211 | 0 | 31. 12. 2024. |
0,12348 % | Barclays Bank PLC | 65.122 | 5.620 | 31. 12. 2024. |
0,11527 % | SEI Investments Management Corporation | 60.795 | 7.525 | 31. 12. 2024. |
0,11527 % | Nuveen Asset Management, LLC | 60.795 | 58.896 | 31. 12. 2024. |
0,11377 % | Klencke (Barbara M.D.) | 60.000 | 60.000 | 21. 1. 2025. |
0,11098 % | LSV Asset Management | 58.530 | -1.620 | 31. 1. 2025. |
0,09229 % | Garcia (Peter S) | 48.673 | -761 | 14. 8. 2024. |
0,08164 % | Vanguard Personalized Indexing Management, LLC | 43.056 | 14.399 | 31. 12. 2024. |
0,08061 % | Rhumbline Advisers Ltd. Partnership | 42.516 | 405 | 31. 12. 2024. |
0,07961 % | AQR Capital Management, LLC | 41.985 | 13.479 | 31. 12. 2024. |
0,07954 % | Nan Fung Life Sciences | 41.950 | 0 | 31. 12. 2024. |
0,07774 % | Deka Investment GmbH | 41.000 | 16.700 | 31. 12. 2023. |
0,07774 % | Deka Vermögensmanagement GmbH | 41.000 | 0 | 31. 12. 2024. |
0,07034 % | Citadel Advisors LLC | 37.095 | 37.095 | 31. 12. 2024. |
0,06257 % | Hemrajani (Rekha) | 33.000 | 30.000 | 2. 12. 2024. |
0,06143 % | Pinto (Shelly) | 32.398 | -2.221 | 6. 1. 2025. |
0,06071 % | Cubist Systematic Strategies, LLC | 32.021 | -351.491 | 31. 12. 2024. |
0,06013 % | Wealth Enhancement Advisory Services, LLC | 31.710 | 0 | 31. 12. 2024. |
0,05961 % | Citi Investment Research (US) | 31.436 | 5.884 | 31. 12. 2024. |
0,05957 % | The Financial Advisory Group, Inc | 31.417 | 0 | 31. 3. 2024. |
0,05496 % | Avantis Investors | 28.985 | 8.467 | 31. 3. 2024. |
0,04974 % | Dimensional Fund Advisors, L.P. | 26.233 | -11.413 | 31. 12. 2024. |
0,04599 % | SG Americas Securities, L.L.C. | 24.256 | -3.138 | 31. 12. 2024. |
0,03944 % | Dimensional Fund Advisors, Ltd. | 20.801 | 0 | 30. 11. 2024. |
0,03920 % | Mellon Investments Corporation | 20.676 | 0 | 31. 12. 2024. |
0,03878 % | Jane Street Capital, L.L.C. | 20.454 | -7.464 | 31. 12. 2024. |
0,03586 % | Mirae Asset Global Investments (USA) LLC | 18.913 | -1.069 | 31. 12. 2024. |
0,03318 % | JSF Financial, LLC | 17.500 | 17.500 | 31. 12. 2024. |
0,03248 % | Corebridge Financial Inc. | 17.129 | -1.093 | 31. 12. 2024. |
0,03206 % | Commonwealth Financial Network | 16.909 | 1.069 | 31. 12. 2024. |
0,03063 % | HSBC Global Asset Management (UK) Limited | 16.154 | 2.235 | 31. 12. 2024. |
0,03053 % | Wells Fargo Bank, N.A. | 16.099 | 5.603 | 31. 12. 2024. |
0,03034 % | Abaris Investment Management AG | 16.000 | 8.000 | 31. 12. 2023. |
0,02934 % | HC Advisors, LLC | 15.475 | -300 | 31. 12. 2024. |
0,02881 % | Moneta Group Investment Advisors, LLC | 15.196 | 15.196 | 31. 12. 2024. |
0,02873 % | JPMorgan Private Bank (United States) | 15.150 | 353 | 31. 12. 2024. |
0,02865 % | Group One Trading, L.P. | 15.112 | -203 | 31. 12. 2024. |
0,02762 % | Simplex Trading, LLC | 14.567 | -2.579 | 31. 12. 2024. |
0,02507 % | Lido Advisors, LLC | 13.220 | 13.220 | 31. 12. 2024. |
0,02502 % | INTECH Investment Management LLC | 13.198 | 13.198 | 31. 12. 2024. |
0,02374 % | New York State Common Retirement Fund | 12.522 | 0 | 31. 12. 2024. |
0,02165 % | BNP Paribas Securities Corp. North America | 11.417 | 11.417 | 31. 12. 2024. |
0,02014 % | T. Rowe Price International Ltd | 10.622 | 0 | 31. 12. 2024. |
0,01973 % | Abel Hall, LLC | 10.406 | 10.406 | 31. 12. 2024. |
0,01533 % | ProShare Advisors LLC | 8.086 | -1.067 | 31. 1. 2025. |
0,01532 % | BlueStar Investment Managers SA | 8.080 | 0 | 30. 11. 2024. |
0,01328 % | Florida State Board of Administration | 7.005 | 0 | 30. 6. 2024. |
0,01166 % | Police and Firemen's Retirement System of New Jersey | 6.148 | 6.148 | 31. 12. 2024. |
0,01120 % | Northern Trust Global Investments | 5.905 | -34.670 | 31. 12. 2024. |
0,01102 % | J.P. Morgan Securities plc | 5.811 | -199 | 31. 12. 2024. |
0,01085 % | Principal Global Investors (Equity) | 5.721 | 0 | 31. 12. 2024. |
0,01062 % | Mercer Global Investments Management Ltd | 5.603 | 0 | 30. 4. 2024. |
0,00948 % | Tower Research Capital LLC | 5.001 | -2.346 | 31. 12. 2024. |
0,00937 % | BlackRock Advisors, LLC | 4.942 | 0 | 31. 8. 2024. |