6,88096 % | ARK Investment Management LLC | 12.983.002 | 288.777 | 30. 9. 2023 |
6,68024 % | Casdin Capital, LLC | 12.604.275 | −3.430 | 30. 6. 2023 |
5,49467 % | Novartis AG | 10.367.340 | 0 | 10. 4. 2023 |
5,02022 % | BlackRock Institutional Trust Company, N.A. | 9.472.149 | 243.527 | 30. 6. 2023 |
4,63294 % | Nikko Asset Management Co., Ltd. | 8.741.437 | 4.411.248 | 30. 6. 2023 |
4,13788 % | The Vanguard Group, Inc. | 7.807.350 | 102.342 | 30. 6. 2023 |
3,95866 % | Madryn Asset Management, LP | 7.469.202 | 0 | 30. 6. 2023 |
2,76433 % | Tikvah Management LLC | 5.215.740 | 1.001.000 | 30. 6. 2023 |
2,75547 % | Millennium Management LLC | 5.199.020 | −621.917 | 30. 6. 2023 |
2,60043 % | Point72 Asset Management, L.P. | 4.906.490 | 45.427 | 30. 6. 2023 |
1,92241 % | Gold (Larry) | 3.627.197 | −5.505.869 | 31. 12. 2022 |
1,80373 % | Foresite Capital Management, LLC | 3.403.276 | −113.196 | 30. 6. 2023 |
1,65982 % | Geode Capital Management, L.L.C. | 3.131.743 | 107.899 | 30. 6. 2023 |
1,56473 % | State Street Global Advisors (US) | 2.952.331 | 40.876 | 30. 6. 2023 |
1,35664 % | Marshall Wace LLP | 2.559.708 | 0 | 30. 6. 2023 |
1,35053 % | Barclays Bank PLC | 2.548.174 | −20.928 | 30. 6. 2023 |
1,16562 % | Magnetar Capital Partners LP | 2.199.292 | −100.725 | 30. 6. 2023 |
0,99154 % | Redmile Group, LLC | 1.870.839 | 0 | 30. 6. 2023 |
0,89917 % | Nan Fung Group Holdings Ltd | 1.696.558 | 0 | 30. 6. 2023 |
0,79500 % | Perceptive Advisors LLC | 1.500.000 | 0 | 30. 6. 2023 |
0,70691 % | Morgan Stanley Investment Management Inc. (US) | 1.333.804 | 151.807 | 30. 6. 2023 |
0,63684 % | Northern Trust Investments, Inc. | 1.201.587 | 1.406 | 30. 6. 2023 |
0,61514 % | Charles Schwab Investment Management, Inc. | 1.160.653 | 33.947 | 30. 6. 2023 |
0,52176 % | Nikko Asset Management Americas, Inc. | 984.457 | 273.530 | 31. 12. 2022 |
0,46015 % | Zweig-DiMenna Associates, Inc. | 868.218 | −400.000 | 30. 6. 2023 |
0,42683 % | Gagnon Securities LLC | 805.337 | −26.764 | 30. 6. 2023 |
0,42388 % | Monashee Investment Management, LLC | 799.784 | −190.077 | 30. 6. 2023 |
0,41096 % | BlackRock Financial Management, Inc. | 775.403 | −9.176 | 30. 6. 2023 |
0,39994 % | Goldman Sachs & Company, Inc. | 754.599 | 137.291 | 30. 6. 2023 |
0,32728 % | Dimensional Fund Advisors, L.P. | 617.509 | 537.524 | 30. 6. 2023 |
0,32100 % | Gagnon Advisors, LLC | 605.671 | 92.703 | 30. 6. 2023 |
0,24796 % | Driehaus Capital Management, LLC | 467.856 | 0 | 30. 6. 2023 |
0,24192 % | Voya Investments, LLC | 456.455 | 0 | 30. 4. 2023 |
0,23850 % | General American Investors Company, Inc. | 450.000 | 0 | 30. 6. 2023 |
0,23210 % | Parametric Portfolio Associates LLC | 437.917 | 8.577 | 30. 6. 2023 |
0,23197 % | Saba Capital Management, L.P. | 437.676 | −18.779 | 30. 6. 2023 |
0,23193 % | BlackRock Investment Management, LLC | 437.611 | 24.438 | 30. 6. 2023 |
0,22525 % | Quake (Stephen Ph.D.) | 425.000 | 0 | 10. 4. 2023 |
0,22069 % | BofA Global Research (US) | 416.401 | −78.695 | 30. 6. 2023 |
0,21975 % | Nuveen LLC | 414.633 | 0 | 30. 6. 2023 |
0,21200 % | RBF Capital, LLC | 400.000 | −116.018 | 30. 6. 2023 |
0,21018 % | Lillis (Charles M) | 396.576 | 3.430 | 10. 4. 2023 |
0,20901 % | BNY Mellon Asset Management | 394.351 | −9.461 | 30. 6. 2023 |
0,18428 % | Schweizerische Nationalbank | 347.700 | 44.200 | 30. 6. 2023 |
0,17225 % | Intellectus Partners, LLC | 325.000 | 0 | 30. 6. 2023 |
0,14896 % | Johnson & Johnson Innovation-JJDC, Inc. | 281.052 | 0 | 30. 6. 2023 |
0,14491 % | Boothbay Fund Management, LLC | 273.422 | −11.741 | 30. 6. 2023 |
0,13193 % | Northern Trust Global Investments | 248.927 | 132.684 | 30. 6. 2023 |
0,13103 % | Cowen & Co., LLC | 247.226 | 0 | 30. 6. 2023 |
0,12257 % | Rhumbline Advisers Ltd. Partnership | 231.258 | −7.027 | 30. 6. 2023 |
0,11295 % | JP Morgan Asset Management | 213.109 | 18.252 | 30. 6. 2023 |
0,10240 % | Morgan Stanley & Co. LLC | 193.203 | −4.078 | 30. 6. 2023 |
0,10140 % | AllianceBernstein L.P. | 191.320 | 32.820 | 30. 6. 2023 |
0,10110 % | California State Teachers Retirement System | 190.758 | 9.942 | 30. 6. 2023 |
0,09727 % | Connor, Clark & Lunn Investment Management Ltd. | 183.520 | −128.143 | 30. 6. 2023 |
0,09156 % | BlackRock Investment Management (UK) Ltd. | 172.756 | 0 | 30. 6. 2023 |
0,09100 % | UBS Asset Management (Switzerland) | 171.701 | 0 | 31. 3. 2023 |
0,09013 % | Invesco Capital Management LLC | 170.048 | −1.819 | 30. 6. 2023 |
0,07065 % | Oak Family Advisors, LLC | 133.296 | −21.033 | 30. 9. 2023 |
0,06890 % | Kent Lake Capital LLC | 129.995 | 129.995 | 30. 6. 2023 |
0,06690 % | Mellon Investments Corporation | 126.235 | −16.638 | 30. 6. 2023 |
0,06514 % | Legal & General Investment Management Ltd. | 122.907 | 67.185 | 30. 6. 2023 |
0,06230 % | UBS Financial Services, Inc. | 117.546 | 45.899 | 30. 6. 2023 |
0,06002 % | D. E. Shaw & Co., L.P. | 113.248 | −93.859 | 30. 6. 2023 |
0,05981 % | Credit Suisse Funds AG | 112.857 | 8.333 | 30. 6. 2023 |
0,05830 % | Tamarack Advisers, LP | 110.000 | −365.000 | 30. 6. 2023 |
0,05326 % | Commonwealth Financial Network | 100.500 | 500 | 30. 6. 2023 |
0,05300 % | Edgewood Management LLC | 100.000 | 0 | 30. 6. 2023 |
0,05164 % | Post (Richard A) | 97.430 | 40.000 | 10. 4. 2023 |
0,05074 % | Susquehanna International Group, LLP | 95.727 | −34.672 | 30. 6. 2023 |
0,04874 % | Inspire Advisors, LLC | 91.969 | 91.969 | 30. 6. 2023 |
0,04823 % | Abaris Investment Management AG | 91.000 | −60.000 | 30. 4. 2023 |
0,04800 % | Towercrest Capital Management, LLC | 90.575 | 90.575 | 30. 6. 2023 |
0,04606 % | BlackRock Advisors (UK) Limited | 86.907 | −259 | 30. 9. 2023 |
0,04573 % | Avantis Investors | 86.292 | 32.909 | 30. 9. 2023 |
0,04416 % | MetLife Investment Management, LLC | 83.329 | 0 | 30. 6. 2023 |
0,04202 % | T. Rowe Price International Ltd | 79.285 | 1.362 | 30. 6. 2023 |
0,04157 % | Cox (Troy M) | 78.430 | −25.070 | 10. 4. 2023 |
0,04135 % | DWS Investments UK Limited | 78.019 | −19.290 | 30. 6. 2023 |
0,04065 % | Jump Financial, LLC | 76.690 | 76.690 | 30. 6. 2023 |
0,04026 % | American Century Investment Management, Inc. | 75.956 | 42.025 | 30. 6. 2023 |
0,03885 % | Goldman Sachs Asset Management, L.P. | 73.296 | −15.036 | 30. 6. 2023 |
0,03856 % | SunAmerica Asset Management, LLC | 72.749 | −1.584 | 30. 6. 2023 |
0,03668 % | SG Americas Securities, L.L.C. | 69.212 | 55.626 | 30. 9. 2023 |
0,03640 % | Citadel Advisors LLC | 68.673 | −57.560 | 30. 6. 2023 |
0,03567 % | BlackRock Asset Management Ireland Limited | 67.311 | 4.604 | 30. 6. 2023 |
0,03445 % | Lauxera Capital Partners | 65.000 | 0 | 31. 8. 2023 |
0,03444 % | Hightower Advisors, LLC | 64.984 | 1.482 | 30. 6. 2023 |
0,03443 % | Manulife Investment Management (North America) Limited | 64.962 | 4.117 | 30. 6. 2023 |
0,03419 % | Janus Henderson Investors | 64.509 | −1.673.305 | 30. 6. 2023 |
0,03392 % | Caspar Asset Management S.A. | 64.000 | 9.000 | 31. 12. 2022 |
0,03392 % | Vaughan Nelson Investment Management, L.P. | 63.998 | 22.936 | 30. 6. 2023 |
0,03345 % | Public Employees' Retirement Association of CO | 63.118 | 0 | 30. 6. 2023 |
0,03322 % | Emerge Canada Inc | 62.683 | 0 | 31. 8. 2023 |
0,03178 % | Voya Investment Management LLC | 59.960 | 4.481 | 30. 6. 2023 |
0,03163 % | Dimensional Fund Advisors, Ltd. | 59.681 | 0 | 31. 8. 2023 |
0,03152 % | Royce Investment Partners | 59.470 | 6.370 | 30. 6. 2023 |
0,03053 % | Wells Fargo Bank, N.A. | 57.606 | 29.922 | 30. 6. 2023 |
0,02915 % | Corient Private Wealth LLC | 55.000 | 55.000 | 30. 6. 2023 |
0,02688 % | Rice Hall James & Associates, LLC | 50.714 | −1.516 | 31. 1. 2022 |