5,13343 % | New Enterprise Associates (NEA) | 5.736.363 | −850.000 | 30. 9. 2021 |
5,10089 % | Avoro Capital Advisors LLC | 5.700.000 | 0 | 30. 9. 2021 |
4,67795 % | Eventide Asset Management, LLC | 5.227.376 | −4.282.624 | 30. 9. 2021 |
4,24143 % | BlackRock Institutional Trust Company, N.A. | 4.739.590 | 223.922 | 30. 9. 2021 |
2,92755 % | Magnetar Capital Partners LP | 3.271.390 | 3.271.390 | 30. 9. 2021 |
2,80997 % | Pentwater Capital Management LP | 3.140.000 | 3.140.000 | 30. 9. 2021 |
2,79485 % | Frazier Healthcare Partners | 3.123.107 | 0 | 30. 9. 2021 |
2,28814 % | Gabelli Funds, LLC | 2.556.885 | 2.229.785 | 30. 9. 2021 |
2,11806 % | Omni Partners US LLC | 2.366.824 | 2.366.824 | 30. 9. 2021 |
1,72129 % | ARP Americas LP | 1.923.455 | 1.923.455 | 30. 9. 2021 |
1,42928 % | Westchester Capital Management, LLC | 1.597.153 | 1.597.153 | 30. 9. 2021 |
1,27179 % | State Street Global Advisors (US) | 1.421.166 | 102.280 | 30. 9. 2021 |
1,25800 % | AQR Capital Management, LLC | 1.405.754 | 1.383.207 | 30. 9. 2021 |
1,19021 % | Spring Creek Capital, LLC | 1.330.000 | 1.330.000 | 30. 9. 2021 |
1,08246 % | AllianceBernstein L.P. | 1.209.595 | 1.109.295 | 30. 9. 2021 |
1,07703 % | Goldman Sachs & Company, Inc. | 1.203.525 | 749.719 | 30. 9. 2021 |
1,02938 % | Candriam Belgium S.A. | 1.150.280 | 360.182 | 30. 9. 2021 |
1,02018 % | Alpine Associates Management Inc. | 1.140.000 | 1.140.000 | 30. 9. 2021 |
1,01570 % | Segantii Capital Management Limited | 1.135.000 | 1.135.000 | 30. 9. 2021 |
0,99004 % | J.P. Morgan Securities LLC | 1.106.326 | 1.106.326 | 30. 9. 2021 |
0,80540 % | Carlson Capital, L.P. | 900.000 | 900.000 | 30. 9. 2021 |
0,79313 % | Fairmount Funds Management LLC | 886.281 | −10.000 | 30. 9. 2021 |
0,76084 % | Geode Capital Management, L.L.C. | 850.207 | 10.318 | 30. 9. 2021 |
0,71457 % | Citadel Advisors LLC | 798.500 | −3.368.259 | 30. 9. 2021 |
0,71318 % | Franklin Advisers, Inc. | 796.939 | −2.913.196 | 30. 9. 2021 |
0,68656 % | Morgan Stanley & Co. LLC | 767.192 | 715.868 | 30. 9. 2021 |
0,67692 % | Driehaus Capital Management, LLC | 756.426 | 500.000 | 30. 9. 2021 |
0,60869 % | Northern Trust Investments, Inc. | 680.183 | −34.383 | 30. 9. 2021 |
0,56244 % | Rock Springs Capital Management LP | 628.500 | 0 | 30. 9. 2021 |
0,52533 % | BlackRock Advisors (UK) Limited | 587.030 | −12.031 | 31. 10. 2021 |
0,51438 % | Brinker Capital Inc. | 574.793 | 371.800 | 31. 8. 2021 |
0,50949 % | QVT Financial LP | 569.333 | 569.333 | 30. 9. 2021 |
0,50449 % | BlackRock Asset Management Ireland Limited | 563.743 | 43.566 | 30. 9. 2021 |
0,49644 % | The Vanguard Group, Inc. | 554.749 | 155.450 | 30. 9. 2021 |
0,49549 % | Millennium Management LLC | 553.684 | 345.612 | 30. 9. 2021 |
0,49381 % | Norges Bank Investment Management (NBIM) | 551.812 | 551.812 | 31. 12. 2020 |
0,44661 % | Weiss Multi-Strategy Advisers LLC | 499.069 | 499.069 | 30. 9. 2021 |
0,42911 % | Nuveen LLC | 479.509 | 6.650 | 30. 9. 2021 |
0,42356 % | GLG Partners LP | 473.310 | 473.310 | 30. 9. 2021 |
0,41702 % | ACT Capital Management, L.L.C. | 466.000 | 1.000 | 30. 9. 2021 |
0,41460 % | Medical Strategy GmbH | 463.291 | 0 | 30. 6. 2021 |
0,39188 % | BlackRock Financial Management, Inc. | 437.910 | 194.160 | 30. 9. 2021 |
0,39113 % | Morgan Stanley Canada Limited | 437.068 | 328.768 | 30. 9. 2021 |
0,38800 % | Columbus Circle Investors | 433.574 | 431.017 | 31. 12. 2020 |
0,37898 % | Crabel Capital Management, L.L.C. | 423.490 | 423.490 | 30. 9. 2021 |
0,37880 % | Water Island Capital, LLC | 423.290 | 126.546 | 30. 9. 2021 |
0,33973 % | Susquehanna International Group, LLP | 379.627 | 277.635 | 30. 9. 2021 |
0,32867 % | JPMorgan Asset Management U.K. Limited | 367.278 | 367.278 | 30. 9. 2021 |
0,31310 % | Barclays Capital Inc. | 349.870 | 349.870 | 30. 9. 2021 |
0,30516 % | Hamblin Watsa Investment Counsel Ltd. | 341.000 | 341.000 | 30. 9. 2021 |
0,30251 % | Cowen Investment Management LLC | 338.042 | 338.042 | 30. 9. 2021 |
0,29709 % | Group One Trading, L.P. | 331.989 | 284.618 | 30. 9. 2021 |
0,29146 % | BlackRock Investment Management, LLC | 325.687 | −7.451 | 30. 9. 2021 |
0,28964 % | TIG Advisors, L.L.C. | 323.658 | 323.658 | 30. 9. 2021 |
0,27742 % | Mangrove Partners | 310.000 | 310.000 | 30. 9. 2021 |
0,27588 % | Candriam S.A. (France) | 308.285 | 308.285 | 30. 9. 2021 |
0,27073 % | LMR Partners LLP | 302.522 | 302.522 | 30. 9. 2021 |
0,26847 % | Picton Mahoney Asset Management | 300.000 | 300.000 | 30. 9. 2021 |
0,25676 % | BofA Global Research (US) | 286.918 | 63.117 | 30. 9. 2021 |
0,23746 % | Western Standard, LLC | 265.355 | 265.355 | 30. 9. 2021 |
0,20135 % | Balyasny Asset Management LP | 225.000 | 225.000 | 30. 9. 2021 |
0,19071 % | Charles Schwab Investment Management, Inc. | 213.112 | 5.759 | 30. 9. 2021 |
0,17898 % | Affinity Asset Advisors LLC | 200.000 | 200.000 | 30. 9. 2021 |
0,17781 % | Knott Partners Management, LLC | 198.699 | 0 | 30. 9. 2021 |
0,17468 % | Bardin Hill Investment Partners LP | 195.192 | 195.192 | 30. 9. 2021 |
0,17130 % | Marshall Wace LLP | 191.423 | −695.760 | 30. 9. 2021 |
0,17122 % | LPL Financial LLC | 191.328 | −53.145 | 30. 9. 2021 |
0,16306 % | BNY Mellon Asset Management | 182.210 | 10.476 | 30. 9. 2021 |
0,16059 % | Morgan Stanley Smith Barney LLC | 179.450 | 20.356 | 30. 9. 2021 |
0,15550 % | Jane Street Capital, L.L.C. | 173.761 | 162.463 | 30. 9. 2021 |
0,15409 % | Schweizerische Nationalbank | 172.190 | 4.400 | 30. 9. 2021 |
0,15007 % | Moore Capital Management, LP | 167.700 | 167.700 | 30. 9. 2021 |
0,14318 % | S. Muoio & Co. LLC | 160.000 | 160.000 | 30. 9. 2021 |
0,13818 % | Odey Asset Management LLP | 154.409 | 154.409 | 30. 9. 2021 |
0,13447 % | Vident Investment Advisory, LLC | 150.259 | −10.732 | 30. 9. 2021 |
0,13108 % | Credit Suisse Securities (USA) LLC | 146.474 | 144.556 | 30. 9. 2021 |
0,12520 % | Woodline Partners LP | 139.907 | −1.726.166 | 30. 9. 2021 |
0,12366 % | Vivaldi Asset Management, LLC | 138.187 | 138.187 | 30. 9. 2021 |
0,11850 % | Rhumbline Advisers Ltd. Partnership | 132.421 | 4.038 | 30. 9. 2021 |
0,11329 % | Equitec Proprietary Markets, LLC | 126.597 | 126.597 | 30. 9. 2021 |
0,11320 % | State of Wisconsin Investment Board | 126.500 | 1.758 | 30. 9. 2021 |
0,11186 % | Angelo, Gordon & Co., L.P. | 125.000 | 125.000 | 30. 9. 2021 |
0,10917 % | Mellon Investments Corporation | 121.993 | 25.825 | 30. 9. 2021 |
0,10395 % | CSS, LLC | 116.154 | 53.901 | 30. 9. 2021 |
0,10332 % | Capstone Investment Advisors, LLC | 115.451 | 115.451 | 30. 9. 2021 |
0,10202 % | HRT Financial LP | 113.999 | 113.999 | 30. 9. 2021 |
0,09791 % | Parametric Portfolio Associates LLC | 109.415 | 85.261 | 30. 9. 2021 |
0,09754 % | Havens Advisors, L.L.C. | 109.000 | 109.000 | 30. 9. 2021 |
0,09566 % | Stifel Nicolaus Investment Advisors | 106.900 | 25.250 | 30. 9. 2021 |
0,08990 % | Tudor Investment Corporation | 100.454 | 100.454 | 30. 9. 2021 |
0,08949 % | Polar Asset Management Partners Inc. | 100.000 | 100.000 | 30. 9. 2021 |
0,08786 % | Chartwell Investment Partners, LLC | 98.177 | 0 | 30. 9. 2021 |
0,08650 % | SG Americas Securities, L.L.C. | 96.664 | 96.664 | 30. 9. 2021 |
0,08540 % | TD Asset Management Inc. | 95.435 | −214.820 | 30. 9. 2021 |
0,08218 % | Northern Trust Global Investments | 91.836 | 2.773 | 30. 9. 2021 |
0,07607 % | Abaris Investment Management AG | 85.000 | 85.000 | 31. 12. 2020 |
0,07159 % | ERSTE-SPARINVEST Kapitalanlagegesellschaft mbH | 80.000 | 0 | 31. 8. 2021 |
0,07119 % | Knights of Columbus | 79.553 | 575 | 30. 9. 2021 |
0,06965 % | Credit Suisse Asset Management | 77.829 | 21.994 | 30. 9. 2021 |
0,06837 % | British Columbia Investment Management Corp. | 76.398 | −368.157 | 30. 9. 2021 |