8,98 % | Avoro Capital Advisors LLC | 2.565.555 | 0 | 31. 12. 2023 |
8,52 % | The Vanguard Group, Inc. | 2.432.038 | 35.632 | 31. 12. 2023 |
8,34 % | Fidelity Management & Research Company LLC | 2.381.205 | −82.166 | 31. 12. 2023 |
6,14 % | Krishnan (Krish S) | 1.752.262 | −25.000 | 25. 3. 2024 |
6,07 % | Redmile Group, LLC | 1.733.189 | −270.178 | 31. 12. 2023 |
5,75 % | Krishnan (Suma M) | 1.640.882 | −25.000 | 25. 3. 2024 |
5,74 % | BlackRock Institutional Trust Company, N.A. | 1.639.280 | 120.409 | 31. 12. 2023 |
4,33 % | State Street Global Advisors (US) | 1.237.497 | 205.670 | 31. 12. 2023 |
3,46 % | Frazier Healthcare Partners | 988.460 | 0 | 31. 12. 2023 |
2,54 % | Jennison Associates LLC | 724.344 | 383.495 | 31. 12. 2023 |
2,17 % | Lord, Abbett & Co. LLC | 618.458 | −52.853 | 31. 12. 2023 |
1,93 % | Dimensional Fund Advisors, L.P. | 550.806 | 30.169 | 31. 12. 2023 |
1,79 % | Geode Capital Management, L.L.C. | 511.246 | 28.011 | 31. 12. 2023 |
1,69 % | Woodline Partners LP | 481.979 | 160.035 | 31. 12. 2023 |
1,66 % | Credit Suisse Funds AG | 474.484 | 241.361 | 31. 12. 2023 |
1,61 % | Hood River Capital Management LLC | 458.513 | −1.976 | 31. 12. 2023 |
1,45 % | T. Rowe Price Associates, Inc. | 413.813 | 169.616 | 31. 12. 2023 |
0,96 % | Morgan Stanley & Co. LLC | 275.124 | 36.452 | 31. 12. 2023 |
0,93 % | Medical Strategy GmbH | 265.798 | 2.000 | 31. 12. 2023 |
0,90 % | Balyasny Asset Management LP | 256.604 | 223.962 | 31. 12. 2023 |
0,88 % | TimesSquare Capital Management, LLC | 250.470 | 127.435 | 31. 12. 2023 |
0,85 % | SEB Investment Management AB | 244.061 | 0 | 31. 12. 2023 |
0,85 % | Nuveen LLC | 243.733 | 10.080 | 31. 12. 2023 |
0,85 % | First Turn Management, LLC | 242.185 | 242.185 | 31. 12. 2023 |
0,69 % | Driehaus Capital Management, LLC | 196.386 | −2.297 | 31. 12. 2023 |
0,69 % | Braidwell LP | 196.200 | 118.703 | 31. 12. 2023 |
0,68 % | Pictet Asset Management Ltd. | 192.875 | −180.937 | 31. 12. 2023 |
0,67 % | Northern Trust Investments, Inc. | 191.560 | 5.440 | 31. 12. 2023 |
0,65 % | C WorldWide Asset Management Fondsmaeglerselskab A/S | 185.809 | 0 | 31. 12. 2023 |
0,65 % | Charles Schwab Investment Management, Inc. | 185.038 | 5.258 | 31. 12. 2023 |
0,63 % | JPMorgan Asset Management U.K. Limited | 179.444 | −8.734 | 31. 12. 2023 |
0,61 % | Victory Capital Management Inc. | 172.879 | −36.608 | 31. 12. 2023 |
0,60 % | Fidelity Investments Canada ULC | 170.459 | −4.066 | 31. 12. 2023 |
0,60 % | Baker Bros. Advisors LP | 169.934 | 0 | 31. 12. 2023 |
0,56 % | Fred Alger Management, LLC | 160.335 | −7.150 | 31. 12. 2023 |
0,55 % | Allspring Global Investments, LLC | 158.425 | 99.101 | 31. 3. 2024 |
0,48 % | Goldman Sachs & Company, Inc. | 137.265 | 32.011 | 31. 12. 2023 |
0,48 % | Eventide Asset Management, LLC | 136.485 | 136.485 | 31. 12. 2023 |
0,43 % | Handelsbanken Kapitalförvaltning AB | 123.200 | 10.400 | 31. 12. 2023 |
0,39 % | S Squared Technology, LLC | 110.215 | 2.000 | 31. 12. 2023 |
0,38 % | Janney (Daniel Spencer) | 107.362 | −125.000 | 25. 3. 2024 |
0,36 % | Rock Springs Capital Management LP | 103.969 | 13.409 | 31. 12. 2023 |
0,36 % | OrbiMed Advisors, LLC | 103.700 | 103.700 | 31. 12. 2023 |
0,34 % | Capital Research Global Investors | 97.147 | 97.147 | 31. 3. 2024 |
0,34 % | Verition Fund Management LLC | 95.958 | −31.112 | 31. 12. 2023 |
0,32 % | Goldman Sachs Asset Management, L.P. | 90.788 | 11.698 | 31. 12. 2023 |
0,30 % | Integral Health Asset Management, LLC | 85.000 | 15.000 | 31. 12. 2023 |
0,29 % | Rafferty Asset Management LLC | 84.021 | 12.215 | 31. 12. 2023 |
0,29 % | Rossi (Dino A) | 83.691 | 0 | 25. 3. 2024 |
0,28 % | BofA Global Research (US) | 81.233 | 18.008 | 31. 12. 2023 |
0,28 % | Eversept Partners, LP | 80.798 | −27.973 | 31. 12. 2023 |
0,26 % | Schroder Investment Management Ltd. (SIM) | 74.945 | 74.945 | 31. 12. 2023 |
0,25 % | Nuveen Asset Management, LLC | 71.732 | 43.151 | 31. 12. 2023 |
0,25 % | Marshall Wace LLP | 70.901 | 61.373 | 31. 12. 2023 |
0,24 % | D. E. Shaw & Co., L.P. | 67.141 | 11.384 | 31. 12. 2023 |
0,23 % | Decheng Capital LLC | 65.772 | 65.772 | 31. 12. 2023 |
0,22 % | Barclays Bank PLC | 64.062 | 24.542 | 31. 12. 2023 |
0,22 % | Wellington Management Company, LLP | 63.799 | −96 | 29. 2. 2024 |
0,22 % | BlackRock Financial Management, Inc. | 61.986 | −3.167 | 31. 12. 2023 |
0,21 % | BNY Mellon Asset Management | 60.419 | 871 | 31. 12. 2023 |
0,20 % | ACT Capital Management, L.L.C. | 58.300 | −700 | 30. 9. 2022 |
0,19 % | Candriam Luxembourg S.A. | 55.000 | 0 | 29. 2. 2024 |
0,19 % | Candriam Belgium S.A. | 55.000 | −15.000 | 31. 12. 2023 |
0,19 % | BlackRock Investment Management, LLC | 54.308 | 390 | 31. 12. 2023 |
0,19 % | Monarch Partners Asset Management LLC | 53.905 | 7.411 | 31. 12. 2022 |
0,18 % | AHL Partners LLP | 50.836 | 50.836 | 31. 12. 2023 |
0,18 % | Jane Street Capital, L.L.C. | 50.618 | −24.508 | 31. 12. 2023 |
0,18 % | Ghost Tree Capital, LLC | 50.000 | −30.000 | 31. 12. 2023 |
0,17 % | Nicholas Investment Partners, L.P. | 49.073 | −306.538 | 31. 12. 2023 |
0,16 % | International Biotechnology Trust PLC | 46.092 | 147 | 30. 9. 2023 |
0,16 % | Voya Investment Management LLC | 45.853 | 17.413 | 31. 12. 2023 |
0,16 % | Invesco Advisers, Inc. | 44.544 | 33.720 | 31. 12. 2023 |
0,15 % | ExodusPoint Capital Management, LP | 42.502 | 14.752 | 31. 12. 2023 |
0,15 % | Arctic Fund Management AS | 42.154 | 8.180 | 29. 2. 2024 |
0,14 % | TD Asset Management Inc. | 40.962 | 18.542 | 31. 12. 2023 |
0,14 % | Soleus Capital Management, L.P. | 40.000 | −77.892 | 31. 12. 2023 |
0,14 % | Putnam Investment Management, L.L.C. | 39.322 | 4.529 | 31. 12. 2023 |
0,14 % | BNP Paribas Securities Corp. North America | 39.072 | 10.057 | 31. 12. 2023 |
0,13 % | PGIM Securities Investment Trust Enterprise | 37.800 | −200 | 31. 12. 2023 |
0,13 % | Citi Investment Research (US) | 36.566 | 779 | 31. 12. 2023 |
0,13 % | Mutual of America Capital Management LLC | 36.388 | −1.151 | 31. 12. 2023 |
0,13 % | Schweizerische Nationalbank | 35.900 | −3.500 | 31. 12. 2023 |
0,12 % | Mellon Investments Corporation | 35.287 | 2.873 | 31. 12. 2023 |
0,12 % | Hennion & Walsh Asset Management, Inc. | 33.154 | 1.756 | 31. 3. 2024 |
0,11 % | BlackRock Advisors (UK) Limited | 32.616 | 1.224 | 31. 3. 2024 |
0,11 % | CastleArk Management, LLC | 32.350 | 20.930 | 31. 12. 2023 |
0,11 % | Rhumbline Advisers Ltd. Partnership | 31.785 | −618 | 31. 12. 2023 |
0,11 % | Parametric Portfolio Associates LLC | 31.232 | −8.113 | 31. 12. 2023 |
0,11 % | UBS Financial Services, Inc. | 30.760 | 30.760 | 31. 12. 2023 |
0,10 % | Kennedy Capital Management LLC | 29.673 | 29.673 | 31. 12. 2023 |
0,10 % | Manulife Investment Management (North America) Limited | 29.250 | 8.813 | 31. 12. 2023 |
0,10 % | BlackRock Asset Management Ireland Limited | 27.592 | −3.944 | 31. 12. 2023 |
0,09 % | AllianceBernstein L.P. | 25.900 | 0 | 31. 12. 2023 |
0,09 % | Schonfeld Strategic Advisors LLC | 25.566 | −58.069 | 31. 12. 2023 |
0,09 % | Affinity Asset Advisors LLC | 25.000 | −32.500 | 31. 12. 2023 |
0,09 % | Franklin Advisers, Inc. | 24.866 | 370 | 31. 12. 2023 |
0,09 % | New Jersey Division of Investment | 24.804 | 4.475 | 31. 12. 2023 |
0,08 % | Carson Wealth Management Group | 23.850 | −6.719 | 31. 3. 2024 |
0,08 % | Scout Investments, Inc. | 23.611 | 23.611 | 29. 2. 2024 |
0,08 % | GW&K Investment Management, LLC | 23.600 | 23.600 | 31. 1. 2024 |