16,36437 % | Sofinnova Investments, Inc | 3.606.707 | 0 | 31. 12. 2021 |
13,59283 % | VenBio Partners LLC | 2.995.859 | −677.515 | 26. 4. 2022 |
9,80939 % | Novo Holdings A/S | 2.161.990 | −8.110 | 25. 2. 2022 |
8,14279 % | Longitude Capital Management Co., LLC | 1.794.671 | 1.794.671 | 11. 8. 2020 |
6,81359 % | Medicxi Ventures (UK) LLP | 1.501.716 | 0 | 31. 12. 2021 |
6,05740 % | Omega Fund Management, LLC | 1.335.050 | 0 | 31. 12. 2021 |
6,04925 % | Decheng Capital China Life Sciences USD Fund I, L.P. | 1.333.254 | −100 | 31. 12. 2021 |
5,92843 % | Clough Capital Partners, LP | 1.306.626 | −260.700 | 31. 12. 2021 |
4,63296 % | Krieg (Arthur M) | 1.021.105 | 10.802 | 18. 6. 2021 |
4,38850 % | Fidelity Management & Research Company LLC | 967.226 | 1.000 | 31. 12. 2021 |
2,63095 % | The Vanguard Group, Inc. | 579.861 | 243.274 | 31. 12. 2021 |
2,45810 % | Sectoral Asset Management Inc. | 541.766 | 0 | 31. 12. 2021 |
0,48321 % | Bridgeway Capital Management, LLC | 106.500 | 0 | 31. 12. 2021 |
0,42348 % | Ensign Peak Advisors, Inc. | 93.334 | −26.581 | 31. 12. 2021 |
0,30868 % | RBF Capital, LLC | 68.034 | −800 | 31. 12. 2021 |
0,18267 % | Geode Capital Management, L.L.C. | 40.260 | 0 | 31. 12. 2021 |
0,13862 % | BlackRock Institutional Trust Company, N.A. | 30.551 | 575 | 31. 12. 2021 |
0,13612 % | Federated Hermes Equity Management Company of Pennsylvania | 30.000 | 10.000 | 31. 12. 2021 |
0,11166 % | Cambridge Trust Company | 24.609 | 0 | 31. 12. 2021 |
0,08819 % | BlackRock Financial Management, Inc. | 19.437 | 0 | 31. 12. 2021 |
0,05030 % | State Street Global Advisors (US) | 11.087 | 0 | 31. 12. 2021 |
0,04824 % | Millennium Management LLC | 10.633 | 10.633 | 31. 12. 2021 |
0,03630 % | Chaudhary (Kleem) | 8.000 | 0 | 23. 4. 2021 |
0,01849 % | Morgan Stanley & Co. LLC | 4.075 | 1 | 31. 12. 2021 |
0,00907 % | U.S. Bancorp Asset Management, Inc. | 2.000 | 0 | 31. 12. 2021 |
0,00819 % | BlackRock Investment Management, LLC | 1.806 | 0 | 31. 12. 2021 |
0,00819 % | Lord, Abbett & Co. LLC | 1.806 | 0 | 28. 2. 2022 |
0,00538 % | Manulife Investment Management (North America) Limited | 1.186 | 0 | 28. 2. 2022 |
0,00505 % | BofA Global Research (US) | 1.112 | −2.258 | 31. 12. 2021 |
0,00501 % | UBS Financial Services, Inc. | 1.105 | 922 | 31. 12. 2021 |
0,00261 % | BlackRock Japan Co., Ltd. | 575 | 0 | 31. 12. 2021 |
0,00091 % | Midwest Financial | 200 | 0 | 31. 3. 2022 |
0,00076 % | RBC Capital Partners | 168 | 0 | 31. 12. 2021 |
0,00042 % | Federated Hermes MDTA LLC | 92 | 92 | 31. 12. 2021 |
0,00015 % | Wells Fargo Bank, N.A. | 33 | 0 | 31. 12. 2021 |
0 % | Ergoteles Capital | 0 | −25.870 | 31. 12. 2021 |
0 % | HRT Financial LP | 0 | −18.298 | 31. 12. 2021 |
0 % | Advisory Services Network, LLC | 0 | −7.800 | 30. 9. 2021 |
0 % | Zimmer Partners, LP | 0 | −25.000 | 31. 12. 2020 |
0 % | BMO Nesbitt Burns Inc. | 0 | −280 | 30. 6. 2021 |
0 % | Principal Funds, Inc. | 0 | −1.478 | 30. 6. 2021 |
0 % | DWS Investments UK Limited | 0 | −5.639 | 30. 6. 2021 |
0 % | Assenagon Asset Management S.A. | 0 | −199 | 30. 6. 2021 |
0 % | Pacific Asset Management | 0 | −1.100 | 30. 6. 2021 |
0 % | ProShare Advisors LLC | 0 | −2.494 | 30. 6. 2021 |
0 % | Laurie J. Hall Trustee | 0 | −100.530 | 31. 3. 2021 |
0 % | Tower Research Capital LLC | 0 | −1.426 | 31. 12. 2021 |
0 % | Northern Trust Global Investments | 0 | −8.015 | 30. 6. 2021 |
0 % | DNCA Investments | 0 | −71.261 | 31. 12. 2021 |
0 % | CPP Investment Board | 0 | −10.000 | 30. 6. 2021 |
0 % | Morgan Stanley & Co. International Plc | 0 | −46 | 31. 12. 2021 |
0 % | ProFund Advisors LLC | 0 | −194 | 31. 7. 2021 |
0 % | Renaissance Technologies LLC | 0 | −10.667 | 31. 12. 2021 |
0 % | Moore Capital Management, LP | 0 | −10.000 | 31. 12. 2020 |
0 % | PGIM Quantitative Solutions LLC | 0 | −1.554 | 30. 4. 2021 |
0 % | Charles Schwab Investment Management, Inc. | 0 | −19.146 | 30. 6. 2021 |
0 % | Legal & General Investment Management Ltd. | 0 | −876 | 30. 6. 2021 |
0 % | DWS Investment GmbH | 0 | −134.760 | 30. 9. 2021 |
0 % | Vaughan Nelson Investment Management, L.P. | 0 | −290 | 30. 6. 2021 |
0 % | Citi Investment Research (US) | 0 | −1 | 30. 9. 2021 |
0 % | AXA Rosenberg Investment Management LLC | 0 | −2.371 | 30. 6. 2021 |
0 % | PNC Wealth Management | 0 | −5.000 | 31. 12. 2021 |
0 % | T. Rowe Price Associates, Inc. | 0 | −145 | 30. 6. 2021 |
0 % | State Teachers Retirement System of Ohio | 0 | −19.300 | 30. 6. 2021 |
0 % | Morgan Stanley Investment Management Inc. (US) | 0 | −77 | 30. 9. 2021 |
0 % | SunAmerica Asset Management, LLC | 0 | −5.217 | 30. 6. 2021 |
0 % | Goldman Sachs & Company, Inc. | 0 | −12.600 | 31. 12. 2020 |
0 % | Nuveen LLC | 0 | −16.328 | 30. 6. 2021 |
0 % | JPMorgan Private Bank (United States) | 0 | −3.531 | 30. 6. 2021 |
0 % | Ameritas Investment Partners, Inc. | 0 | −430 | 30. 6. 2021 |
0 % | BNY Mellon Asset Management | 0 | −15.196 | 30. 6. 2021 |
0 % | Northern Trust Investments, Inc. | 0 | −73.344 | 30. 6. 2021 |
0 % | Jacobs Levy Equity Management, Inc. | 0 | −36.511 | 31. 12. 2021 |
0 % | Federated Hermes Global Investment Management Corp. | 0 | −10.781 | 30. 6. 2021 |
0 % | BMO Capital Markets (US) | 0 | −328 | 30. 6. 2021 |
0 % | Westfield Capital Management Company, L.P. | 0 | −77 | 30. 6. 2021 |
0 % | J.P. Morgan Securities LLC | 0 | −185 | 31. 12. 2021 |
0 % | Alberta Investment Management Corporation | 0 | −25.000 | 30. 9. 2021 |
0 % | New York State Common Retirement Fund | 0 | −77 | 30. 9. 2021 |
0 % | California State Teachers Retirement System | 0 | −13.503 | 30. 6. 2021 |
0 % | Mellon Investments Corporation | 0 | −1.992 | 30. 6. 2021 |
0 % | Franklin Mutual Advisers, LLC | 0 | −398 | 30. 6. 2021 |
0 % | Voya Investment Management LLC | 0 | −4.304 | 30. 6. 2021 |
0 % | CaaS Capital Management LP | 0 | −44.966 | 31. 12. 2020 |