19,70856 % | BVF Partners L.P. | 8 748 629 | 0 | 30. 6. 2024 |
17,77333 % | Bellevue Asset Management AG | 7 889 583 | 0 | 30. 6. 2024 |
9,48533 % | Soleus Capital Management, L.P. | 4 210 537 | 620 979 | 30. 6. 2024 |
9,40831 % | Morgan Stanley & Co. LLC | 4 176 348 | -700 | 30. 6. 2024 |
6,68043 % | PFM Health Sciences, LP | 2 965 442 | -14 978 | 30. 6. 2024 |
5,17833 % | RTW Investments L.P. | 2 298 662 | 0 | 30. 6. 2024 |
3,32094 % | Adage Capital Management, L.P. | 1 474 165 | -106 210 | 30. 6. 2024 |
2,26673 % | Janus Henderson Investors | 1 006 202 | -169 040 | 30. 6. 2024 |
1,81585 % | Rhenman & Partners Asset Management AB | 806 054 | -105 766 | 30. 6. 2024 |
1,76707 % | Berger (Franklin Milan) | 784 404 | 22 770 | 16. 1. 2024 |
1,52513 % | Rock Springs Capital Management LP | 677 005 | 0 | 30. 6. 2024 |
0,71128 % | Schonfeld Strategic Advisors LLC | 315 736 | -52 764 | 30. 6. 2024 |
0,58866 % | Medical Strategy GmbH | 261 304 | 15 000 | 30. 6. 2024 |
0,56786 % | Parkman Healthcare Partners LLC | 252 072 | 377 | 30. 6. 2024 |
0,18080 % | CIBC World Markets Inc. | 80 257 | -600 | 30. 6. 2024 |
0,14815 % | Parkinson (David Ross M.D.) | 65 765 | 0 | 16. 1. 2024 |
0,14301 % | D. E. Shaw & Co., L.P. | 63 481 | -1 600 | 30. 6. 2024 |
0,13553 % | Glickman (Richard M) | 60 160 | 3 750 | 24. 4. 2024 |
0,10531 % | American Century Investment Management, Inc. | 46 748 | 572 | 30. 6. 2024 |
0,10402 % | Avantis Investors | 46 176 | 26 132 | 31. 3. 2024 |
0,09821 % | BNP Paribas Securities Corp. North America | 43 595 | 1 100 | 30. 6. 2024 |
0,07885 % | RBC Capital Markets Wealth Management | 35 000 | 5 000 | 30. 6. 2024 |
0,07764 % | Kennedy Capital Management LLC | 34 465 | 34 465 | 30. 6. 2024 |
0,07511 % | Wood (David Sidney) | 33 343 | 0 | 16. 1. 2024 |
0,06759 % | Requadt (Scott) | 30 002 | 0 | 16. 1. 2024 |
0,06050 % | Geode Capital Management, L.L.C. | 26 858 | 0 | 30. 6. 2024 |
0,05660 % | Citadel Advisors LLC | 25 125 | -11 393 | 30. 6. 2024 |
0,03626 % | Tucker Asset Management LLC | 16 097 | 16 097 | 31. 3. 2024 |
0,03205 % | Martin (John Alexander) | 14 229 | 0 | 16. 1. 2024 |
0,02323 % | Two Sigma Investments, LP | 10 313 | 10 313 | 30. 6. 2024 |
0,01752 % | Virsik (Peter) | 7 776 | -694 | 7. 10. 2024 |
0,01352 % | Osaic Holdings, Inc. | 6 000 | 0 | 30. 6. 2024 |
0,01264 % | BlackRock Financial Management, Inc. | 5 609 | 0 | 30. 6. 2024 |
0,01154 % | Cesano (Alessandra) | 5 124 | 0 | 16. 1. 2024 |
0,00649 % | Thorell (Marella) | 2 881 | 0 | 16. 1. 2024 |
0,00563 % | CIBC Private Wealth Management | 2 500 | 0 | 30. 6. 2024 |
0,00462 % | Desjardins Securities Inc. | 2 050 | 2 000 | 30. 6. 2024 |
0,00353 % | UBS Financial Services, Inc. | 1 565 | -2 061 | 30. 6. 2024 |
0,00338 % | Morgan Stanley Smith Barney LLC | 1 500 | 0 | 30. 6. 2024 |
0,00203 % | TD Waterhouse Canada, Inc. | 900 | 0 | 31. 3. 2024 |
0,00175 % | RBC Dominion Securities, Inc. | 775 | 0 | 30. 6. 2024 |
0,00135 % | Laurel Wealth Advisors, LLC | 600 | 0 | 30. 6. 2024 |
0,00121 % | RBC Capital Partners | 537 | 537 | 30. 6. 2024 |
0,00011 % | TD Securities, Inc. | 48 | 0 | 30. 6. 2024 |
0,00005 % | J.P. Morgan Securities plc | 21 | 0 | 30. 6. 2024 |
0,00002 % | BofA Global Research (US) | 8 | 0 | 30. 6. 2024 |
0 % | ACCI Capital Investments SGIIC, SA | 0 | -47 500 | 31. 3. 2023 |
0 % | One Wealth Advisors, LLC | 0 | -8 333 | 31. 3. 2023 |
0 % | Crewe Advisors LLC | 0 | -265 | 30. 6. 2023 |
0 % | Simplex Trading, LLC | 0 | -4 329 | 30. 6. 2024 |
0 % | Cubist Systematic Strategies, LLC | 0 | -34 086 | 31. 3. 2023 |
0 % | Blackstone Alternative Investment Advisors LLC | 0 | -800 | 31. 12. 2023 |
0 % | Hunting Hill Global Capital, LLC | 0 | -10 000 | 31. 12. 2023 |
0 % | Barclays Bank PLC | 0 | -971 | 31. 3. 2024 |
0 % | Group One Trading, L.P. | 0 | -11 175 | 31. 3. 2024 |
0 % | Kapitalo Investimentos Ltda | 0 | -33 400 | 31. 3. 2023 |
0 % | Quantbot Technologies, LP | 0 | -1 751 | 31. 3. 2023 |
0 % | Susquehanna International Group, LLP | 0 | -95 758 | 31. 12. 2023 |
0 % | Connective Capital Management, LLC | 0 | -84 578 | 31. 12. 2023 |
0 % | Tower Research Capital LLC | 0 | -27 | 30. 9. 2023 |
0 % | Northern Trust Global Investments | 0 | -4 661 | 30. 9. 2023 |
0 % | Millennium Management LLC | 0 | -14 052 | 30. 6. 2024 |
0 % | Renaissance Technologies LLC | 0 | -24 234 | 31. 3. 2024 |
0 % | OrbiMed Advisors, LLC | 0 | -842 366 | 31. 12. 2023 |
0 % | Acadian Asset Management LLC | 0 | -15 903 | 31. 12. 2023 |
0 % | Driehaus Capital Management, LLC | 0 | -28 300 | 30. 9. 2023 |
0 % | Wellington Management Company, LLP | 0 | -562 | 30. 6. 2023 |
0 % | State Street Global Advisors (US) | 0 | -24 414 | 30. 9. 2023 |
0 % | Morgan Stanley Investment Management Inc. (US) | 0 | -7 | 30. 6. 2023 |
0 % | Thrivent Asset Management, LLC | 0 | -33 389 | 31. 3. 2023 |
0 % | Bessemer Trust Company, N.A. (US) | 0 | -6 852 | 30. 6. 2023 |
0 % | Northern Trust Investments, Inc. | 0 | -7 828 | 30. 9. 2023 |
0 % | J.P. Morgan Securities LLC | 0 | -29 406 | 31. 12. 2023 |
0 % | Entrypoint Capital LLC | 0 | -4 420 | 30. 6. 2024 |
0 % | Frazier Life Sciences Management, L.P. | 0 | -605 141 | 31. 3. 2023 |
0 % | Privium Fund Management (UK) Ltd | 0 | -20 032 | 31. 3. 2024 |
0 % | Ally Bridge Group NY LLC | 0 | -236 583 | 30. 6. 2023 |
0 % | Jump Financial, LLC | 0 | -27 500 | 31. 3. 2023 |
0 % | Avidity Partners Management LP | 0 | -1 855 400 | 31. 3. 2023 |
0 % | Walleye Capital LLC | 0 | -20 784 | 31. 3. 2023 |