10,00844 % | RTW Investments L.P. | 7.582.396 | 60.537 | 30.09.2021 |
7,14650 % | Eli Lilly and Company | 5.414.185 | 0 | 01.04.2021 |
5,97480 % | BlackRock Institutional Trust Company, N.A. | 4.526.507 | 21.658 | 30.09.2021 |
5,12959 % | State Street Global Advisors (US) | 3.886.181 | 1.297.119 | 30.09.2021 |
4,89336 % | The Vanguard Group, Inc. | 3.707.210 | 86.857 | 30.09.2021 |
4,06578 % | Bain Capital Life Sciences Investors, LLC | 3.080.237 | 0 | 30.09.2021 |
3,54091 % | T. Rowe Price Associates, Inc. | 2.682.596 | 699.671 | 30.09.2021 |
3,24260 % | Aquilo Capital Management, LLC | 2.456.595 | 643.203 | 30.09.2021 |
2,12232 % | Morgan Stanley & Co. LLC | 1.607.870 | 626.309 | 30.09.2021 |
1,78465 % | Woodline Partners LP | 1.352.048 | 351.723 | 30.09.2021 |
1,78268 % | Assenagon Asset Management S.A. | 1.350.558 | 780.152 | 30.09.2021 |
1,76962 % | Two Sigma Investments, LP | 1.340.661 | 715.555 | 30.09.2021 |
1,72984 % | Maverick Capital, Ltd. | 1.310.530 | 2.454 | 30.09.2021 |
1,71512 % | Polar Capital LLP | 1.299.372 | 214.559 | 30.09.2021 |
1,70572 % | Commodore Capital LP | 1.292.251 | 1.292.251 | 30.09.2021 |
1,68052 % | JPMorgan Asset Management U.K. Limited | 1.273.160 | 208.538 | 30.09.2021 |
1,64970 % | EcoR1 Capital, LLC | 1.249.812 | 1.249.812 | 30.09.2021 |
1,57164 % | Geode Capital Management, L.L.C. | 1.190.676 | 2.981 | 30.09.2021 |
1,45364 % | UBS Financial Services, Inc. | 1.101.275 | -234.545 | 30.09.2021 |
1,12951 % | Palo Alto Investors LP | 855.713 | 523.000 | 30.09.2021 |
1,12496 % | BlackRock Financial Management, Inc. | 852.273 | -5.754 | 30.09.2021 |
1,06519 % | Pictet Asset Management Ltd. | 806.987 | 803.987 | 30.09.2021 |
1,05596 % | Great Point Partners, LLC | 799.999 | 799.999 | 30.09.2021 |
0,93674 % | Eagle Asset Management, Inc. | 709.674 | -608.373 | 30.09.2021 |
0,92569 % | Banque Lombard Odier & Cie SA | 701.305 | 65.294 | 30.09.2021 |
0,92397 % | Invus Public Equities Advisors, LLC | 700.000 | -100.000 | 30.09.2021 |
0,87741 % | Northern Trust Investments, Inc. | 664.723 | -6.796 | 30.09.2021 |
0,83870 % | Point72 Asset Management, L.P. | 635.400 | -85.000 | 30.09.2021 |
0,78114 % | Marshall Wace LLP | 591.790 | 591.790 | 30.09.2021 |
0,77542 % | Dafna Capital Management, LLC | 587.456 | 76.700 | 30.09.2021 |
0,72377 % | Goldman Sachs & Company, Inc. | 548.327 | 15.627 | 30.09.2021 |
0,70433 % | Wellington Management Company, LLP | 533.604 | -2.765.749 | 30.09.2021 |
0,68277 % | Charles Schwab Investment Management, Inc. | 517.263 | 17.340 | 30.09.2021 |
0,67795 % | Fidelity Management & Research Company LLC | 513.612 | -105.100 | 30.09.2021 |
0,54440 % | Nuveen LLC | 412.439 | 8.187 | 30.09.2021 |
0,53660 % | Eagle Health Investments LP | 406.525 | 245.400 | 30.09.2021 |
0,52852 % | Invesco Capital Management LLC | 400.406 | 234.317 | 30.09.2021 |
0,51926 % | Candriam Belgium S.A. | 393.390 | -24.855 | 30.09.2021 |
0,47680 % | Millennium Management LLC | 361.222 | 25.736 | 30.09.2021 |
0,43429 % | Voloridge Investment Management, LLC | 329.016 | 266.797 | 30.09.2021 |
0,41788 % | Medical Strategy GmbH | 316.588 | -58.160 | 30.06.2021 |
0,36688 % | Balyasny Asset Management LP | 277.949 | 191.393 | 30.09.2021 |
0,34477 % | Citadel Advisors LLC | 261.200 | -72.328 | 30.09.2021 |
0,33028 % | Goldman Sachs Asset Management, L.P. | 250.217 | 172.463 | 30.09.2021 |
0,30710 % | UBS Asset Management (Americas), Inc. | 232.658 | -5.076 | 30.09.2021 |
0,29988 % | Federated Hermes MDTA LLC | 227.187 | -167.114 | 30.09.2021 |
0,29463 % | Emerald Advisers LLC | 223.213 | -734.271 | 30.09.2021 |
0,29182 % | APG Asset Management N.V. | 221.083 | 221.083 | 30.06.2020 |
0,28586 % | Carson Wealth Management Group | 216.565 | 71.374 | 30.06.2021 |
0,28085 % | BlackRock Investment Management, LLC | 212.773 | -19.851 | 30.09.2021 |
0,27910 % | AXA Investment Managers UK Ltd. | 211.448 | -31.320 | 30.09.2021 |
0,27678 % | Parkman Healthcare Partners LLC | 209.686 | -95.000 | 30.09.2021 |
0,27303 % | Russell Investments Trust Company | 206.845 | 28.079 | 30.09.2021 |
0,26984 % | Mirae Asset Global Investments (USA) LLC | 204.430 | 39.179 | 30.09.2021 |
0,26885 % | Schonfeld Strategic Advisors LLC | 203.680 | 158.795 | 30.09.2021 |
0,23826 % | Silvercrest Asset Management Group LLC | 180.502 | 33.686 | 30.09.2021 |
0,22114 % | Connor, Clark & Lunn Investment Management Ltd. | 167.538 | 79.527 | 30.09.2021 |
0,21626 % | BNY Mellon Asset Management | 163.841 | 1.444 | 30.09.2021 |
0,20229 % | JP Morgan Asset Management | 153.256 | -36.590 | 30.09.2021 |
0,20182 % | Schweizerische Nationalbank | 152.900 | 4.000 | 30.09.2021 |
0,19943 % | Voya Investment Management LLC | 151.085 | -3.274 | 30.09.2021 |
0,19860 % | AllianceBernstein L.P. | 150.459 | -35.398 | 30.09.2021 |
0,18953 % | Rafferty Asset Management LLC | 143.589 | 73.769 | 30.09.2021 |
0,17766 % | First Trust Advisors L.P. | 134.599 | 44.222 | 30.09.2021 |
0,17305 % | Renaissance Technologies LLC | 131.100 | -100 | 30.09.2021 |
0,16935 % | Bank J. Safra Sarasin AG (Asset Management) | 128.296 | 28.148 | 30.09.2021 |
0,16821 % | Citi Investment Research (US) | 127.437 | -14.431 | 30.09.2021 |
0,15958 % | Alphacrest Capital Management LLC | 120.900 | 120.900 | 30.09.2021 |
0,15819 % | Duality Group | 119.842 | 119.842 | 30.09.2021 |
0,15667 % | Mellon Investments Corporation | 118.692 | 20.761 | 30.09.2021 |
0,15328 % | Morgan Stanley Investment Management Inc. (US) | 116.123 | 1.157 | 30.09.2021 |
0,14845 % | JPMorgan Private Bank (United States) | 112.466 | -4.894 | 30.09.2021 |
0,14652 % | Susquehanna International Group, LLP | 111.005 | -41.688 | 30.09.2021 |
0,14520 % | Hudson Bay Capital Management LP | 110.000 | 25.024 | 30.09.2021 |
0,13651 % | D. E. Shaw & Co., L.P. | 103.422 | 103.422 | 30.09.2021 |
0,12576 % | Alps Advisors, Inc. | 95.276 | 86.586 | 30.09.2021 |
0,12566 % | PanAgora Asset Management Inc. | 95.203 | 57.365 | 30.09.2021 |
0,12449 % | California State Teachers Retirement System | 94.311 | -642 | 30.09.2021 |
0,12262 % | Evolutionary Tree Capital Management, LLC | 92.898 | -48.426 | 30.09.2021 |
0,12130 % | Lyxor Asset Management | 91.895 | -450 | 31.10.2021 |
0,12108 % | AQR Capital Management, LLC | 91.733 | 52.741 | 30.09.2021 |
0,11855 % | Arctic Fund Management AS | 89.814 | -67.000 | 30.09.2021 |
0,11720 % | BlackRock Advisors (UK) Limited | 88.793 | 2.580 | 31.10.2021 |
0,11708 % | State of Wisconsin Investment Board | 88.700 | 0 | 30.09.2021 |
0,10733 % | BofA Global Research (US) | 81.313 | -66.797 | 30.09.2021 |
0,10486 % | Foord Asset Management (Pty) Limited | 79.445 | 79.445 | 30.06.2021 |
0,10359 % | BlackRock Asset Management Ireland Limited | 78.478 | -7.240 | 30.09.2021 |
0,10322 % | Deka Investment GmbH | 78.200 | 78.200 | 31.12.2020 |
0,10288 % | Rhumbline Advisers Ltd. Partnership | 77.944 | -1.119 | 30.09.2021 |
0,10123 % | Northern Trust Global Investments | 76.689 | -768 | 30.09.2021 |
0,10037 % | Parametric Portfolio Associates LLC | 76.037 | -9.834 | 30.09.2021 |
0,09792 % | TD Asset Management Inc. | 74.186 | 0 | 30.09.2021 |
0,09556 % | Foord Asset Management (Singapore) Pte. Ltd. | 72.399 | 72.399 | 30.06.2021 |
0,09522 % | UBS Asset Management (Switzerland) | 72.137 | -5.674 | 30.09.2021 |
0,09244 % | Advisors Asset Management, Inc. | 70.029 | 22.425 | 30.09.2021 |
0,09073 % | BlackRock Investment Management (UK) Ltd. | 68.736 | 5.581 | 30.09.2021 |
0,08787 % | Credit Suisse Asset Management | 66.572 | 129 | 30.09.2021 |
0,08678 % | Manchester Capital Management LLC | 65.742 | 0 | 30.09.2021 |
0,07971 % | Legal & General Investment Management Ltd. | 60.386 | 44.332 | 30.09.2021 |
0,07787 % | Cubist Systematic Strategies, LLC | 58.993 | 44.923 | 30.09.2021 |