27,72168 % | Brightstar Associates LLC | 23.973.709 | 914.001 | 07.02.2024 |
6,69290 % | Deerfield Management Company, L.P. | 5.788.024 | -1.109.582 | 31.12.2023 |
6,01295 % | Armistice Capital LLC | 5.200.000 | 588.000 | 31.12.2023 |
5,55220 % | Redmile Group, LLC | 4.801.540 | 326.156 | 31.12.2023 |
5,53346 % | BlackRock Institutional Trust Company, N.A. | 4.785.332 | 483.317 | 31.12.2023 |
5,08135 % | The Vanguard Group, Inc. | 4.394.354 | 38.654 | 31.12.2023 |
2,85709 % | State Street Global Advisors (US) | 2.470.813 | 159.695 | 31.12.2023 |
2,13922 % | Polar Capital LLP | 1.850.000 | 100.000 | 31.12.2023 |
2,10152 % | Goldman Sachs & Company, Inc. | 1.817.391 | 389.957 | 31.12.2023 |
1,90336 % | Morgan Stanley & Co. LLC | 1.646.030 | 443.104 | 31.12.2023 |
1,80580 % | Dimensional Fund Advisors, L.P. | 1.561.654 | 92.410 | 31.12.2023 |
1,63071 % | Nuveen LLC | 1.410.239 | 97.103 | 31.12.2023 |
1,41224 % | Geode Capital Management, L.L.C. | 1.221.308 | 84.701 | 31.12.2023 |
1,38474 % | Emerald Advisers LLC | 1.197.526 | 1.126.978 | 31.12.2023 |
1,35232 % | Braidwell LP | 1.169.490 | -2.166.731 | 31.12.2023 |
1,18154 % | Frazier Healthcare Partners | 1.021.800 | 651.800 | 31.12.2023 |
1,06096 % | Jefferies LLC | 917.515 | 178.772 | 31.12.2023 |
0,97171 % | Two Sigma Investments, LP | 840.332 | 626.526 | 31.12.2023 |
0,93654 % | Assenagon Asset Management S.A. | 809.923 | 0 | 31.12.2023 |
0,80416 % | BlackRock Financial Management, Inc. | 695.434 | 44.019 | 31.12.2023 |
0,75423 % | Millennium Management LLC | 652.254 | 298.064 | 31.12.2023 |
0,66718 % | New Leaf Venture Partners LLC | 576.975 | -632.596 | 31.12.2023 |
0,64873 % | Parkman Healthcare Partners LLC | 561.025 | -36.378 | 31.12.2023 |
0,59586 % | Charles Schwab Investment Management, Inc. | 515.301 | 13.716 | 31.12.2023 |
0,56670 % | Goldman Sachs Asset Management, L.P. | 490.084 | -98.989 | 31.12.2023 |
0,54032 % | Northern Trust Investments, Inc. | 467.266 | 15.720 | 31.12.2023 |
0,52148 % | Morgan Stanley Investment Management Inc. (US) | 450.972 | 343.749 | 31.12.2023 |
0,52087 % | Medical Strategy GmbH | 450.450 | 15.000 | 31.12.2023 |
0,51463 % | Jacobs Levy Equity Management, Inc. | 445.056 | -283.670 | 31.12.2023 |
0,50567 % | Renaissance Technologies LLC | 437.300 | 125.900 | 31.12.2023 |
0,45819 % | Woodline Partners LP | 396.239 | 396.239 | 31.12.2023 |
0,44943 % | D. E. Shaw & Co., L.P. | 388.663 | 71.702 | 31.12.2023 |
0,40703 % | Norges Bank Investment Management (NBIM) | 352.000 | 352.000 | 31.12.2023 |
0,38807 % | Flynn (Daniel Lee) | 335.600 | -1.655 | 16.06.2023 |
0,38348 % | Walleye Capital LLC | 331.632 | 331.632 | 31.12.2023 |
0,36422 % | UBS Asset Management (Americas), Inc. | 314.975 | -2.132 | 31.12.2023 |
0,32321 % | Schonfeld Strategic Advisors LLC | 279.511 | 46.611 | 31.12.2023 |
0,32191 % | Cubist Systematic Strategies, LLC | 278.385 | 58.761 | 31.12.2023 |
0,31414 % | Algert Global LLC | 271.671 | 178.261 | 31.12.2023 |
0,30214 % | Citadel Advisors LLC | 261.288 | 26.264 | 31.12.2023 |
0,29041 % | Connor, Clark & Lunn Investment Management Ltd. | 251.145 | 178.973 | 31.12.2023 |
0,28492 % | DWS Investment GmbH | 246.400 | 14.529 | 31.12.2023 |
0,27666 % | DWS Investments UK Limited | 239.253 | 216.880 | 31.12.2023 |
0,27272 % | PanAgora Asset Management Inc. | 235.845 | 144.097 | 31.12.2023 |
0,26018 % | Ghost Tree Capital, LLC | 225.000 | -100.000 | 31.12.2023 |
0,25224 % | Parametric Portfolio Associates LLC | 218.136 | -63.588 | 31.12.2023 |
0,24746 % | PSP Investments | 214.000 | 0 | 31.12.2023 |
0,24454 % | BlackRock Asset Management Ireland Limited | 211.478 | -9.155 | 31.12.2023 |
0,22459 % | Voloridge Investment Management, LLC | 194.229 | 194.229 | 31.12.2023 |
0,20361 % | BlackRock Advisors (UK) Limited | 176.081 | 2.818 | 31.03.2024 |
0,19002 % | BlackRock Investment Management, LLC | 164.328 | 9.593 | 31.12.2023 |
0,18954 % | Barclays Bank PLC | 163.913 | 49.872 | 31.12.2023 |
0,18290 % | Dhanak (Dashyant) | 158.175 | 17.275 | 15.02.2024 |
0,17576 % | HOOPP Investment Management | 152.000 | 39.000 | 31.12.2023 |
0,17041 % | BNY Mellon Asset Management | 147.373 | -2.891 | 31.12.2023 |
0,16140 % | Rafferty Asset Management LLC | 139.582 | -158 | 31.12.2023 |
0,15725 % | Trexquant Investment LP | 135.994 | 135.994 | 31.12.2023 |
0,15279 % | GSA Capital Partners LLP | 132.130 | -30.569 | 31.12.2023 |
0,14607 % | UBS Financial Services, Inc. | 126.323 | 68.064 | 31.12.2023 |
0,13848 % | Qube Research & Technologies Ltd | 119.760 | 44.004 | 31.12.2023 |
0,13636 % | UBS O'Connor LLC | 117.920 | -35.817 | 31.12.2023 |
0,13521 % | ExodusPoint Capital Management, LP | 116.932 | -218.953 | 31.12.2023 |
0,13009 % | LifeSci Fund Management LLC | 112.500 | -19.500 | 31.12.2023 |
0,12350 % | Point72 Asset Management, L.P. | 106.800 | -515.633 | 31.12.2023 |
0,11986 % | HRT Financial LP | 103.651 | 46.153 | 31.12.2023 |
0,11525 % | Pictet Asset Management (Japan) Ltd. | 99.666 | 99.666 | 31.10.2023 |
0,11135 % | Sunesis Advisors, LLC | 96.299 | 0 | 31.12.2023 |
0,10589 % | Jane Street Capital, L.L.C. | 91.573 | -6.244 | 31.12.2023 |
0,10123 % | Jupiter Asset Management Ltd. | 87.543 | 25.383 | 31.12.2023 |
0,09973 % | BofA Global Research (US) | 86.250 | -82.407 | 31.12.2023 |
0,09449 % | Susquehanna International Group, LLP | 81.717 | 9.192 | 31.12.2023 |
0,09366 % | Virginia Retirement System | 81.000 | 6.000 | 30.09.2023 |
0,09341 % | Rhumbline Advisers Ltd. Partnership | 80.785 | -10 | 31.12.2023 |
0,09039 % | Columbia Threadneedle Investments (US) | 78.165 | -48.644 | 31.12.2023 |
0,08987 % | Thrivent Asset Management, LLC | 77.720 | -8.931 | 31.12.2023 |
0,08979 % | BNP Paribas Securities Corp. North America | 77.653 | 42.051 | 31.12.2023 |
0,08414 % | Hoerter (Steven L) | 72.763 | 31.836 | 13.12.2023 |
0,08271 % | Aperio Group, LLC | 71.526 | -7.645 | 31.12.2023 |
0,08270 % | Voya Investment Management LLC | 71.517 | 50.166 | 31.12.2023 |
0,08252 % | PDT Partners, LLC | 71.365 | 35.863 | 31.12.2023 |
0,08155 % | Martingale Asset Management, L.P. | 70.526 | 5 | 31.12.2023 |
0,08083 % | Schweizerische Nationalbank | 69.900 | -16.500 | 31.12.2023 |
0,07873 % | UBS Asset Management (Switzerland) | 68.083 | -722 | 31.12.2023 |
0,07718 % | Dimensional Fund Advisors, Ltd. | 66.745 | 0 | 31.01.2024 |
0,07419 % | Nebula Research & Development LLC | 64.159 | 30.990 | 31.12.2023 |
0,07236 % | Citi Investment Research (US) | 62.580 | 2.000 | 31.12.2023 |
0,07212 % | Fisher Investments | 62.372 | 62.372 | 31.12.2023 |
0,06830 % | AQR Capital Management, LLC | 59.070 | 3.422 | 31.12.2023 |
0,06677 % | Goldman Sachs Asset Management International | 57.745 | -7.943 | 31.12.2023 |
0,06670 % | Sherman (Matthew L) | 57.686 | 14.660 | 16.02.2024 |
0,06233 % | Pitman (Jama) | 53.900 | 17.458 | 16.02.2024 |
0,06086 % | Legato Capital Management LLC | 52.636 | 52.636 | 31.03.2024 |
0,06035 % | Northern Trust Global Investments | 52.187 | -2.402 | 31.12.2023 |
0,05952 % | Avantis Investors | 51.474 | 13.440 | 31.03.2024 |
0,05867 % | Campbell & Company, Inc. | 50.735 | 50.735 | 31.12.2023 |
0,05782 % | Deka Vermögensmanagement GmbH | 50.000 | 50.000 | 31.12.2023 |
0,05768 % | Allianz Global Investors GmbH | 49.880 | 0 | 31.01.2024 |
0,05747 % | AllianceBernstein L.P. | 49.700 | -343 | 31.12.2023 |
0,05747 % | Alps Advisors, Inc. | 49.699 | -8.516 | 31.12.2023 |
0,05614 % | Wellington Management Company, LLP | 48.546 | 48.546 | 31.12.2023 |