15,30104 % | Antecip Capital, L.L.C. | 7.344.500 | 0 | 15.04.2024 |
9,65486 % | RTW Investments L.P. | 4.634.331 | 141.652 | 30.06.2024 |
7,78180 % | The Vanguard Group, Inc. | 3.735.263 | 1.724 | 30.06.2024 |
5,94936 % | BlackRock Institutional Trust Company, N.A. | 2.855.693 | 98.721 | 30.06.2024 |
4,91683 % | Fairmount Funds Management LLC | 2.360.077 | 0 | 30.06.2024 |
3,85997 % | Deep Track Capital LP | 1.852.784 | 548.063 | 30.06.2024 |
2,23592 % | Macquarie Investment Management | 1.073.242 | 372.832 | 30.06.2024 |
2,08333 % | RA Capital Management, LP | 1.000.000 | 0 | 30.06.2024 |
1,98958 % | BVF Partners L.P. | 955.000 | 955.000 | 30.06.2024 |
1,95565 % | Eventide Asset Management, LLC | 938.714 | 592.002 | 30.06.2024 |
1,95521 % | State Street Global Advisors (US) | 938.503 | -213 | 30.06.2024 |
1,84353 % | Geode Capital Management, L.L.C. | 884.895 | 39.488 | 30.06.2024 |
1,63869 % | BofA Global Research (US) | 786.573 | 669.746 | 30.06.2024 |
1,56924 % | Citadel Advisors LLC | 753.237 | -390.407 | 30.06.2024 |
1,54352 % | Alethea Capital Management, LLC | 740.888 | 97 | 30.06.2024 |
1,54129 % | Millennium Management LLC | 739.819 | -1.699 | 30.06.2024 |
1,53046 % | Wellington Management Company, LLP | 734.620 | 57.974 | 30.06.2024 |
1,52083 % | Adage Capital Management, L.P. | 730.000 | 215.000 | 30.06.2024 |
1,14389 % | Hood River Capital Management LLC | 549.066 | 28.316 | 30.06.2024 |
1,07611 % | Bellevue Asset Management AG | 516.533 | -168.943 | 30.06.2024 |
1,06127 % | Invesco Advisers, Inc. | 509.411 | 322.829 | 30.06.2024 |
1,03063 % | Fidelity Management & Research Company LLC | 494.703 | 31.361 | 30.06.2024 |
0,99801 % | Point72 Asset Management, L.P. | 479.044 | 100.180 | 30.06.2024 |
0,97381 % | PFM Health Sciences, LP | 467.427 | 0 | 30.06.2024 |
0,95648 % | Perceptive Advisors LLC | 459.111 | -646.230 | 30.06.2024 |
0,87178 % | Coleman (Mark H) | 418.456 | -10.497 | 29.05.2024 |
0,84882 % | Fidelity Institutional Asset Management | 407.433 | 42.225 | 30.06.2024 |
0,84212 % | Norges Bank Investment Management (NBIM) | 404.217 | 209.094 | 30.06.2024 |
0,83333 % | Boxer Capital, L.L.C. | 400.000 | 0 | 30.06.2024 |
0,83333 % | Cormorant Asset Management, LP | 400.000 | 400.000 | 30.06.2024 |
0,78333 % | Avidity Partners Management LP | 376.000 | -55.000 | 30.06.2024 |
0,73575 % | Goldman Sachs & Company, Inc. | 353.158 | 182.848 | 30.06.2024 |
0,70260 % | First Turn Management, LLC | 337.246 | -4.927 | 30.06.2024 |
0,66252 % | Woodline Partners LP | 318.011 | -42.117 | 30.06.2024 |
0,64625 % | Sofinnova Investments, Inc | 310.198 | 310.198 | 30.06.2024 |
0,64545 % | Charles Schwab Investment Management, Inc. | 309.818 | 8.744 | 30.06.2024 |
0,63857 % | Tri Locum Partners LP | 306.513 | 203.802 | 30.06.2024 |
0,62500 % | Vestal Point Capital, LP | 300.000 | 300.000 | 30.06.2024 |
0,61228 % | Northern Trust Investments, Inc. | 293.894 | -11.187 | 30.06.2024 |
0,60578 % | Checkpoint Capital L.P. | 290.772 | 158.335 | 30.06.2024 |
0,56060 % | Loomis, Sayles & Company, L.P. | 269.089 | -10.702 | 30.06.2024 |
0,42245 % | Morgan Stanley Smith Barney LLC | 202.778 | 20.734 | 30.06.2024 |
0,35159 % | AllianceBernstein L.P. | 168.762 | 88.608 | 30.06.2024 |
0,35090 % | Jane Street Capital, L.L.C. | 168.434 | -30.645 | 30.06.2024 |
0,34931 % | Jeffs (Roger A) | 167.668 | 0 | 15.04.2024 |
0,33118 % | BlackRock Financial Management, Inc. | 158.966 | 1.675 | 30.06.2024 |
0,31626 % | JP Morgan Asset Management | 151.806 | -6.409 | 30.06.2024 |
0,31250 % | Ghost Tree Capital, LLC | 150.000 | -60.000 | 30.06.2024 |
0,27735 % | U.S. Bancorp Asset Management, Inc. | 133.126 | 421 | 30.09.2024 |
0,27565 % | MPM BioImpact LLC | 132.312 | 18.185 | 30.06.2024 |
0,27186 % | BlackRock Advisors (UK) Limited | 130.494 | 119 | 30.09.2024 |
0,26583 % | Rhenman & Partners Asset Management AB | 127.600 | -16.000 | 30.06.2024 |
0,26417 % | Iridian Asset Management LLC | 126.803 | -102 | 30.09.2024 |
0,26198 % | BlackRock Asset Management Ireland Limited | 125.752 | -13.146 | 30.06.2024 |
0,23614 % | WCM Investment Management | 113.345 | 1.755 | 30.06.2024 |
0,22243 % | ClearBridge Investments, LLC | 106.767 | 17.397 | 30.06.2024 |
0,21930 % | Putnam Investment Management, L.L.C. | 105.266 | 941 | 30.06.2024 |
0,21087 % | HSBC Private Bank (Suisse) S.A. | 101.219 | 101.219 | 31.08.2024 |
0,20991 % | Nuveen LLC | 100.757 | -143.532 | 30.06.2024 |
0,20551 % | Eagle Asset Management, Inc. | 98.645 | -127.870 | 30.06.2024 |
0,20006 % | Frontier Capital Management Company, LLC | 96.027 | -9.317 | 30.06.2024 |
0,19982 % | BNY Mellon Asset Management | 95.913 | 5.278 | 30.06.2024 |
0,19433 % | BlackRock Investment Management, LLC | 93.278 | 6.938 | 30.06.2024 |
0,18524 % | Voya Investment Management LLC | 88.915 | 69.628 | 30.06.2024 |
0,18302 % | Artia Global Partners LP | 87.848 | 0 | 30.06.2024 |
0,17613 % | Medical Strategy GmbH | 84.541 | -6.849 | 30.06.2024 |
0,17102 % | Cannell & Spears LLC | 82.092 | -638 | 30.06.2024 |
0,17016 % | Wells Fargo Bank, N.A. | 81.677 | 70.990 | 30.06.2024 |
0,16667 % | Affinity Asset Advisors LLC | 80.000 | -59.758 | 30.06.2024 |
0,16388 % | Morgan Stanley & Co. LLC | 78.662 | -444.365 | 30.06.2024 |
0,16060 % | Pictet Asset Management (Japan) Ltd. | 77.087 | 77.087 | 30.04.2024 |
0,15838 % | Walleye Capital LLC | 76.023 | -21.097 | 30.06.2024 |
0,15576 % | Neuberger Berman, LLC | 74.767 | -16.889 | 30.06.2024 |
0,15486 % | Privium Fund Management BV | 74.332 | -7.700 | 30.06.2024 |
0,15286 % | Managed Account Advisors LLC | 73.375 | 26.992 | 30.06.2024 |
0,14985 % | Peregrine Capital Management, LLC | 71.929 | -15.444 | 30.09.2024 |
0,14651 % | Lindbrook Capital, LLC | 70.326 | -13.442 | 30.06.2024 |
0,14585 % | SpiderRock Advisors LLC | 70.008 | -11 | 30.06.2024 |
0,14491 % | Scout Investments, Inc. | 69.558 | 35.527 | 30.06.2024 |
0,13226 % | Mellon Investments Corporation | 63.486 | 10.767 | 30.06.2024 |
0,12969 % | DWS Investment Management Americas, Inc. | 62.253 | -884 | 30.06.2024 |
0,12957 % | HighVista Strategies LLC | 62.192 | 13.665 | 30.06.2024 |
0,12634 % | Moody Aldrich Partners, LLC | 60.644 | -1.107 | 30.09.2024 |
0,12604 % | Schweizerische Nationalbank | 60.500 | 0 | 30.06.2024 |
0,12323 % | William Blair & Company, L.L.C. (Research) | 59.151 | -4.396 | 30.06.2024 |
0,12273 % | Schonfeld Strategic Advisors LLC | 58.909 | -1.273 | 30.06.2024 |
0,12146 % | International Biotechnology Trust PLC | 58.300 | 0 | 30.09.2023 |
0,12146 % | Schroder Investment Management Ltd. (SIM) | 58.300 | 0 | 30.06.2024 |
0,12114 % | Hennion & Walsh Asset Management, Inc. | 58.148 | -6.537 | 30.09.2024 |
0,11444 % | Rhumbline Advisers Ltd. Partnership | 54.931 | 2.674 | 30.06.2024 |
0,10417 % | Altium Capital Management LP | 50.000 | -88.000 | 30.06.2024 |
0,10353 % | Baldwin Brothers, LLC. | 49.695 | 0 | 30.09.2024 |
0,10208 % | Atika Capital Management LLC | 49.000 | -19.000 | 30.06.2024 |
0,10035 % | Goldman Sachs Asset Management, L.P. | 48.169 | -73.133 | 30.06.2024 |
0,09612 % | INVESCO Asset Management Limited | 46.137 | -10.831 | 30.06.2024 |
0,08980 % | Pizzie (Nick) | 43.104 | 827 | 15.04.2024 |
0,08902 % | Columbia Threadneedle Investments (US) | 42.730 | 33.400 | 30.06.2024 |
0,08481 % | WMS Partners LLC | 40.711 | 0 | 30.06.2024 |
0,08463 % | SEI Investments Management Corporation | 40.624 | 4.970 | 30.06.2024 |
0,08333 % | Wells Fargo Securities, LLC | 40.000 | 40.000 | 30.06.2024 |