8,59771 % | Wellington Management Company, LLP | 7.339.004 | -97.612 | 30/06/2024 |
7,65327 % | BlackRock Institutional Trust Company, N.A. | 6.532.828 | 283.661 | 30/06/2024 |
6,70344 % | Kynam Capital Management LP | 5.722.057 | 62.057 | 30/06/2024 |
5,60230 % | The Vanguard Group, Inc. | 4.782.124 | -129.895 | 30/06/2024 |
4,55534 % | Avoro Capital Advisors LLC | 3.888.437 | -333.785 | 30/06/2024 |
4,41756 % | State Street Global Advisors (US) | 3.770.826 | 148.491 | 30/09/2024 |
4,23340 % | Eversept Partners, LP | 3.613.631 | 480.518 | 30/06/2024 |
3,90698 % | Avidity Partners Management LP | 3.335.000 | 922.500 | 30/06/2024 |
3,26014 % | Point72 Asset Management, L.P. | 2.782.853 | 716.168 | 30/06/2024 |
2,52304 % | Sofinnova Investments, Inc | 2.153.669 | 545.129 | 30/06/2024 |
2,25551 % | OrbiMed Advisors, LLC | 1.925.300 | 176.300 | 30/06/2024 |
2,23831 % | Geode Capital Management, L.L.C. | 1.910.623 | 132.075 | 30/06/2024 |
2,14436 % | Marshall Wace LLP | 1.830.427 | -201.632 | 30/06/2024 |
1,81841 % | Two Sigma Investments, LP | 1.552.199 | 377.795 | 30/06/2024 |
1,81345 % | Franklin Advisers, Inc. | 1.547.963 | 72.729 | 30/06/2024 |
1,81060 % | Woodline Partners LP | 1.545.528 | 1.241 | 30/06/2024 |
1,65438 % | StemPoint Capital LP | 1.412.176 | 311.188 | 30/06/2024 |
1,38968 % | Candriam Luxembourg S.A. | 1.186.228 | 0 | 30/09/2024 |
1,32315 % | Goldman Sachs & Company, Inc. | 1.129.438 | 30.137 | 30/06/2024 |
1,24825 % | Millennium Management LLC | 1.065.508 | 383.634 | 30/06/2024 |
1,20080 % | Aisling Capital Management LP | 1.025.000 | 0 | 30/06/2024 |
1,13649 % | Candriam Belgium S.A. | 970.106 | -74.926 | 30/06/2024 |
1,04849 % | Kingdon Capital Management, L.L.C. | 894.993 | 0 | 30/06/2024 |
1,02507 % | Foresite Capital Management, LLC | 875.000 | 0 | 30/06/2024 |
1,00750 % | Adage Capital Management, L.P. | 860.000 | -40.000 | 30/06/2024 |
0,96825 % | Soleus Capital Management, L.P. | 826.500 | 457.500 | 30/06/2024 |
0,96649 % | Commodore Capital LP | 825.000 | 506.149 | 30/06/2024 |
0,96578 % | BlackRock Financial Management, Inc. | 824.394 | 38.560 | 30/06/2024 |
0,96304 % | Sphera Funds Management Ltd. | 822.047 | 9.083 | 30/06/2024 |
0,95177 % | BofA Global Research (US) | 812.433 | -805.740 | 30/06/2024 |
0,92290 % | BNP Paribas Asset Management USA, Inc. | 787.785 | 69.345 | 30/09/2024 |
0,76977 % | Dafna Capital Management, LLC | 657.074 | -2.500 | 30/06/2024 |
0,76880 % | Federated Hermes Global Investment Management Corp. | 656.250 | 117.536 | 30/06/2024 |
0,76674 % | Charles Schwab Investment Management, Inc. | 654.489 | 19.282 | 30/06/2024 |
0,75022 % | First Turn Management, LLC | 640.389 | 640.389 | 30/06/2024 |
0,74384 % | Northern Trust Investments, Inc. | 634.946 | -41.048 | 30/06/2024 |
0,73304 % | ExodusPoint Capital Management, LP | 625.723 | 339.393 | 30/06/2024 |
0,70372 % | Parkman Healthcare Partners LLC | 600.698 | -184.113 | 30/06/2024 |
0,69633 % | Granahan Investment Management, LLC | 594.386 | 197.508 | 30/06/2024 |
0,64806 % | Nuveen LLC | 553.187 | 162.265 | 30/06/2024 |
0,64614 % | Prosight Capital | 551.544 | 551.544 | 30/06/2024 |
0,64306 % | JP Morgan Asset Management | 548.917 | -44.379 | 30/06/2024 |
0,60788 % | Ensign Peak Advisors, Inc. | 518.885 | 4.033 | 30/06/2024 |
0,56667 % | Columbia Threadneedle Investments (US) | 483.712 | 2.811 | 30/06/2024 |
0,54596 % | Assenagon Asset Management S.A. | 466.028 | 37.079 | 30/09/2024 |
0,53097 % | Nantahala Capital Management, LLC | 453.232 | -12.027 | 30/06/2024 |
0,51915 % | Morgan Stanley & Co. LLC | 443.145 | -1.088.823 | 30/06/2024 |
0,50624 % | Algert Global LLC | 432.128 | 6.455 | 30/06/2024 |
0,49163 % | Saturn V Capital Management LP | 419.654 | 21.657 | 30/06/2024 |
0,47469 % | Palo Alto Investors LP | 405.193 | 0 | 30/06/2024 |
0,45379 % | PFM Health Sciences, LP | 387.357 | -271.337 | 30/06/2024 |
0,43346 % | SilverArc Capital Management, LLC | 370.000 | 370.000 | 30/06/2024 |
0,41003 % | Ghost Tree Capital, LLC | 350.000 | 200.000 | 30/06/2024 |
0,35555 % | Goldman Sachs Asset Management, L.P. | 303.499 | 108.246 | 30/06/2024 |
0,34829 % | Qube Research & Technologies Ltd | 297.303 | 203.414 | 30/06/2024 |
0,33251 % | T. Rowe Price Investment Management, Inc. | 283.827 | -2.175.408 | 30/06/2024 |
0,31359 % | Parametric Portfolio Associates LLC | 267.682 | 26.396 | 30/06/2024 |
0,30562 % | Schonfeld Strategic Advisors LLC | 260.876 | -524.768 | 30/06/2024 |
0,28458 % | Macquarie Investment Management | 242.919 | -73 | 30/06/2024 |
0,27136 % | BlackRock Investment Management, LLC | 231.634 | 16.095 | 30/06/2024 |
0,26784 % | HOOPP Investment Management | 228.625 | -551.375 | 30/06/2024 |
0,26769 % | Rhenman & Partners Asset Management AB | 228.500 | 50.000 | 30/06/2024 |
0,25105 % | Renaissance Technologies LLC | 214.300 | 135.200 | 30/06/2024 |
0,24170 % | BNY Mellon Asset Management | 206.319 | 24.260 | 30/06/2024 |
0,23323 % | Peregrine Capital Management, LLC | 199.086 | 427 | 30/09/2024 |
0,22256 % | Citadel Advisors LLC | 189.981 | 156.172 | 30/06/2024 |
0,21515 % | Voya Investment Management LLC | 183.649 | -13.375 | 30/06/2024 |
0,20843 % | Rafferty Asset Management LLC | 177.920 | -195.318 | 30/06/2024 |
0,19648 % | TwinBeech Capital LP | 167.714 | 95.831 | 30/06/2024 |
0,19202 % | Metzger (Michael A) | 163.909 | 3.750 | 08/03/2024 |
0,18158 % | Zimmer Partners, LP | 155.000 | 0 | 30/06/2024 |
0,17961 % | Jane Street Capital, L.L.C. | 153.311 | 39.783 | 30/06/2024 |
0,17643 % | Schweizerische Nationalbank | 150.600 | 0 | 30/06/2024 |
0,17573 % | Casdin Capital, LLC | 150.000 | 0 | 30/06/2024 |
0,17179 % | D. E. Shaw & Co., L.P. | 146.643 | 138.119 | 30/06/2024 |
0,16936 % | Verition Fund Management LLC | 144.566 | -202.296 | 30/06/2024 |
0,16785 % | Crestline Investors, Inc. | 143.280 | 39.570 | 30/06/2024 |
0,16044 % | BlackRock Advisors (UK) Limited | 136.952 | 1.627 | 30/09/2024 |
0,14662 % | UBS Financial Services, Inc. | 125.152 | -144.659 | 30/06/2024 |
0,13974 % | Rhumbline Advisers Ltd. Partnership | 119.285 | 10.291 | 30/06/2024 |
0,13860 % | BlackRock Asset Management Ireland Limited | 118.312 | 1.362 | 30/06/2024 |
0,13417 % | Yelin Lapidot Mutual Funds Management Ltd | 114.530 | 114.530 | 30/09/2023 |
0,12940 % | UBS O'Connor LLC | 110.454 | 2.023 | 30/06/2024 |
0,12696 % | Yelin Lapidot Provident Funds Management Ltd | 108.377 | -6.153 | 30/09/2024 |
0,12163 % | Knott Partners Management, LLC | 103.826 | 38.351 | 30/06/2024 |
0,11953 % | Susquehanna International Group, LLP | 102.027 | -634.121 | 30/06/2024 |
0,11894 % | PGIM Quantitative Solutions LLC | 101.530 | 85.770 | 30/06/2024 |
0,11146 % | Axiom Investors | 95.140 | 1.075 | 30/06/2024 |
0,11049 % | New Jersey Division of Investment | 94.313 | -20.071 | 30/06/2024 |
0,11001 % | Trexquant Investment LP | 93.906 | 19.314 | 30/06/2024 |
0,10934 % | Podlesak (Dennis G) | 93.333 | -2.000 | 08/03/2024 |
0,10857 % | Aperio Group, LLC | 92.675 | 13.305 | 30/06/2024 |
0,09987 % | AllianceBernstein L.P. | 85.250 | 7.790 | 30/06/2024 |
0,09981 % | Wellington Management Singapore Pte. Ltd. | 85.200 | 85.200 | 31/03/2024 |
0,09981 % | Wellington Management Japan Pte Ltd | 85.200 | -54.891 | 30/06/2023 |
0,09879 % | Legal & General Investment Management Ltd. | 84.330 | 14.552 | 30/06/2024 |
0,09754 % | Propel Bio Management, LLC | 83.259 | 0 | 30/06/2024 |
0,09706 % | PanAgora Asset Management Inc. | 82.849 | -154.157 | 30/06/2024 |
0,09069 % | Mellon Investments Corporation | 77.412 | 19.883 | 30/06/2024 |
0,08900 % | Seven Eight Capital, LP | 75.971 | 66.332 | 30/06/2024 |