8,93403 % | The Vanguard Group, Inc. | 15.982.979 | 1.502.753 | 30/06/2024 |
6,68659 % | T. Rowe Price Associates, Inc. | 11.962.303 | 1.424.445 | 30/06/2024 |
6,48953 % | BlackRock Institutional Trust Company, N.A. | 11.609.770 | 1.466.241 | 30/06/2024 |
5,43199 % | Darwin Global Management Ltd | 9.717.822 | 6.176.727 | 23/08/2024 |
3,61913 % | Fidelity Management & Research Company LLC | 6.474.624 | -1.590.617 | 30/06/2024 |
3,28110 % | Capital International Investors | 5.869.888 | 4.249.074 | 30/06/2024 |
3,21795 % | Capital Research Global Investors | 5.756.910 | 547.242 | 30/09/2024 |
2,60617 % | State Street Global Advisors (US) | 4.662.439 | -1.242.688 | 30/06/2024 |
2,03506 % | Geode Capital Management, L.L.C. | 3.640.720 | 476.969 | 30/06/2024 |
2,03472 % | RTW Investments L.P. | 3.640.108 | 1.775.000 | 30/06/2024 |
1,99890 % | Baker Bros. Advisors LP | 3.576.038 | 3.233.038 | 30/06/2024 |
1,93948 % | William Blair Investment Management, LLC | 3.469.728 | -744.991 | 30/06/2024 |
1,53529 % | Macquarie Investment Management | 2.746.628 | -1.152.876 | 30/06/2024 |
1,49005 % | JP Morgan Asset Management | 2.665.692 | 2.475.041 | 30/06/2024 |
1,40961 % | Suvretta Capital Management, LLC | 2.521.800 | 498.800 | 30/06/2024 |
1,39311 % | AllianceBernstein L.P. | 2.492.275 | 345.796 | 30/06/2024 |
1,39152 % | Artisan Partners Limited Partnership | 2.489.431 | 2.489.431 | 30/06/2024 |
1,36163 % | T. Rowe Price Investment Management, Inc. | 2.435.962 | -1.015.618 | 30/06/2024 |
1,31812 % | Franklin Advisers, Inc. | 2.358.111 | -765.103 | 30/06/2024 |
1,19562 % | Palo Alto Investors LP | 2.138.963 | -2.284.406 | 30/06/2024 |
1,16924 % | Janus Henderson Investors | 2.091.778 | -137.685 | 30/06/2024 |
1,11794 % | Deep Track Capital LP | 2.000.000 | -2.783.679 | 30/06/2024 |
1,02223 % | Columbia Threadneedle Investments (US) | 1.828.766 | -28.194 | 30/06/2024 |
0,98235 % | Norges Bank Investment Management (NBIM) | 1.757.425 | 304.400 | 30/06/2024 |
0,96164 % | BlackRock Financial Management, Inc. | 1.720.367 | 771.883 | 30/06/2024 |
0,92664 % | Principal Global Investors (Equity) | 1.657.760 | 218.480 | 30/06/2024 |
0,91948 % | ClearBridge Investments, LLC | 1.644.948 | 714.539 | 30/06/2024 |
0,86641 % | Integral Health Asset Management, LLC | 1.550.000 | 250.000 | 30/06/2024 |
0,84858 % | Fidelity International | 1.518.114 | 797.869 | 30/06/2024 |
0,83350 % | Pictet Asset Management Ltd. | 1.491.135 | -38.873 | 30/06/2024 |
0,74064 % | Adage Capital Management, L.P. | 1.325.000 | 1.075.000 | 30/06/2024 |
0,73527 % | Hood River Capital Management LLC | 1.315.392 | 352.891 | 30/06/2024 |
0,73035 % | Charles Schwab Investment Management, Inc. | 1.306.596 | 179.829 | 30/06/2024 |
0,70325 % | Nuveen LLC | 1.258.118 | 739.952 | 30/06/2024 |
0,69835 % | Marshall Wace LLP | 1.249.351 | -80.697 | 30/06/2024 |
0,69730 % | Northern Trust Investments, Inc. | 1.247.471 | 52.979 | 30/06/2024 |
0,68570 % | Loomis, Sayles & Company, L.P. | 1.226.726 | -265.068 | 30/06/2024 |
0,66993 % | Millennium Management LLC | 1.198.510 | 921.892 | 30/06/2024 |
0,65817 % | Emerald Advisers LLC | 1.177.471 | 43.355 | 30/09/2024 |
0,64594 % | Eversept Partners, LP | 1.155.588 | 1.155.588 | 30/06/2024 |
0,57908 % | Viking Global Investors LP | 1.035.970 | 1.035.970 | 30/06/2024 |
0,57110 % | Bellevue Asset Management AG | 1.021.700 | -1.120.143 | 30/06/2024 |
0,54988 % | Mellon Investments Corporation | 983.727 | -260.105 | 30/06/2024 |
0,52456 % | Wellington Management Company, LLP | 938.434 | 702.209 | 30/06/2024 |
0,51537 % | Voloridge Investment Management, LLC | 922.002 | 866.276 | 30/06/2024 |
0,47977 % | Point72 Asset Management, L.P. | 858.300 | 858.300 | 30/06/2024 |
0,47924 % | Assenagon Asset Management S.A. | 857.360 | 466.306 | 30/09/2024 |
0,46954 % | Jane Street Capital, L.L.C. | 840.000 | 569.027 | 30/06/2024 |
0,46423 % | Fidelity Institutional Asset Management | 830.506 | -423.147 | 30/06/2024 |
0,45567 % | FIL Investment Management (Hong Kong) Limited | 815.200 | -132.873 | 31/08/2024 |
0,45185 % | Rock Springs Capital Management LP | 808.356 | 808.356 | 30/06/2024 |
0,44704 % | Citadel Advisors LLC | 799.746 | -127.817 | 30/06/2024 |
0,43287 % | Frontier Capital Management Company, LLC | 774.404 | 27.073 | 30/06/2024 |
0,42579 % | GW&K Investment Management, LLC | 761.732 | -508.166 | 30/06/2024 |
0,42217 % | American Century Investment Management, Inc. | 755.271 | 52.647 | 30/06/2024 |
0,41923 % | Vestal Point Capital, LP | 750.000 | 0 | 30/06/2024 |
0,41603 % | Jennison Associates LLC | 744.280 | 625.768 | 30/06/2024 |
0,41414 % | Long Focus Capital Management LLC | 740.900 | 309.251 | 30/06/2024 |
0,40940 % | Voya Investment Management LLC | 732.422 | 270.537 | 30/06/2024 |
0,40507 % | Novo Holdings A/S | 724.666 | -75.334 | 30/09/2024 |
0,39271 % | Capital World Investors | 702.567 | 95.961 | 30/09/2024 |
0,37741 % | Eventide Asset Management, LLC | 675.185 | 40.000 | 30/06/2024 |
0,37731 % | Cormorant Asset Management, LP | 675.000 | 100.000 | 30/06/2024 |
0,37320 % | Medical Strategy GmbH | 667.661 | 31.782 | 30/06/2024 |
0,36345 % | Octagon Capital Advisors LP | 650.216 | -489.784 | 30/06/2024 |
0,34936 % | Kingdon Capital Management, L.L.C. | 625.000 | 170.000 | 30/06/2024 |
0,34409 % | Goldman Sachs & Company, Inc. | 615.576 | 101.025 | 30/06/2024 |
0,34399 % | MPM BioImpact LLC | 615.391 | 84.597 | 30/06/2024 |
0,34365 % | BNP Paribas Asset Management USA, Inc. | 614.783 | -287.420 | 30/06/2024 |
0,33634 % | Invesco Advisers, Inc. | 601.708 | 441.429 | 30/06/2024 |
0,33372 % | Fiera Capital Inc. | 597.020 | 597.020 | 30/06/2024 |
0,32564 % | Lord, Abbett & Co. LLC | 582.577 | 233.579 | 30/06/2024 |
0,31750 % | Farallon Capital Management, L.L.C. | 568.000 | 568.000 | 30/06/2024 |
0,31378 % | Goldman Sachs Asset Management, L.P. | 561.356 | 333.196 | 30/06/2024 |
0,31075 % | Candriam Belgium S.A. | 555.934 | 165.734 | 30/06/2024 |
0,30816 % | First Light Asset Management, LLC | 551.303 | 268.537 | 30/06/2024 |
0,29384 % | TD Asset Management Inc. | 525.682 | 98.504 | 30/06/2024 |
0,28946 % | BNP Paribas Asset Management UK Limited | 517.847 | 91.431 | 31/01/2023 |
0,28714 % | Eagle Health Investments LP | 513.700 | 513.700 | 30/06/2024 |
0,27869 % | Fred Alger Management, LLC | 498.572 | 492.951 | 30/06/2024 |
0,27106 % | Morgan Stanley & Co. LLC | 484.933 | -222.711 | 30/06/2024 |
0,26635 % | Candriam Luxembourg S.A. | 476.494 | -49.999 | 30/09/2024 |
0,26483 % | Lewis (William H) | 473.775 | 20.509 | 14/05/2024 |
0,26311 % | Soros Fund Management, L.L.C. | 470.700 | 470.700 | 30/06/2024 |
0,26184 % | BNY Mellon Asset Management | 468.426 | 46.457 | 30/06/2024 |
0,26132 % | Hudson Bay Capital Management LP | 467.500 | -159.310 | 30/06/2024 |
0,25950 % | BofA Global Research (US) | 464.237 | -46.673 | 30/06/2024 |
0,24295 % | BlackRock Investment Management, LLC | 434.632 | 85.630 | 30/06/2024 |
0,24036 % | Avidity Partners Management LP | 430.000 | 430.000 | 30/06/2024 |
0,23969 % | Alyeska Investment Group, L.P. | 428.804 | 228.804 | 30/06/2024 |
0,23096 % | Iron Triangle Partners LP | 413.196 | 413.196 | 30/06/2024 |
0,22747 % | Two Sigma Investments, LP | 406.942 | -769.631 | 30/06/2024 |
0,21807 % | Allspring Global Investments, LLC | 390.134 | 62.061 | 30/09/2024 |
0,20657 % | Columbia Wanger Asset Management, LLC | 369.550 | 0 | 30/06/2024 |
0,20081 % | Samlyn Capital, LLC | 359.254 | -228.380 | 30/06/2024 |
0,20069 % | Ensign Peak Advisors, Inc. | 359.029 | 17.455 | 30/06/2024 |
0,19988 % | Putnam Investment Management, L.L.C. | 357.583 | -64.750 | 30/06/2024 |
0,19907 % | PanAgora Asset Management Inc. | 356.135 | -158.694 | 30/06/2024 |
0,19544 % | Managed Account Advisors LLC | 349.643 | 18.493 | 30/06/2024 |
0,19319 % | Sharoky (Melvin A) | 345.620 | -10.000 | 29/08/2024 |