6,25 % | Boxer Capital, L.L.C. | 4 407 350 | 2 967 350 | 8.01.2024 |
5,35 % | Samsara BioCapital, LLC | 3 768 035 | 900 000 | 29.03.2024 |
5,06 % | New Enterprise Associates (NEA) | 3 568 781 | 0 | 27.03.2024 |
4,90 % | Adage Capital Management, L.P. | 3 450 000 | -250 000 | 31.12.2023 |
4,82 % | Deerfield Management Company, L.P. | 3 400 000 | 0 | 31.12.2023 |
4,49 % | GSK plc | 3 161 432 | 3 161 432 | 27.03.2024 |
4,03 % | EQT Life Sciences | 2 836 539 | 2 836 539 | 8.02.2024 |
3,87 % | Commodore Capital LP | 2 730 000 | 0 | 31.12.2023 |
3,13 % | BlackRock Institutional Trust Company, N.A. | 2 208 990 | -193 835 | 31.12.2023 |
2,21 % | The Vanguard Group, Inc. | 1 560 518 | 61 778 | 31.12.2023 |
15,33 % | RA Capital Management, LP | 10 805 129 | 3 000 000 | 27.03.2024 |
1,89 % | SR One Capital Management, LP | 1 333 333 | 0 | 31.12.2023 |
1,66 % | Wasatch Global Investors Inc | 1 168 492 | -931 207 | 31.03.2024 |
0,93 % | Renaissance Technologies LLC | 657 772 | 145 200 | 31.12.2023 |
0,93 % | Geode Capital Management, L.L.C. | 653 740 | 21 013 | 31.12.2023 |
0,87 % | State Street Global Advisors (US) | 611 849 | 4545 | 31.12.2023 |
0,78 % | Tang Capital Management, LLC | 550 000 | -553 638 | 31.12.2023 |
0,66 % | T. Rowe Price Investment Management, Inc. | 462 838 | 32 488 | 31.12.2023 |
0,64 % | Alyeska Investment Group, L.P. | 450 731 | -549 269 | 31.12.2023 |
0,59 % | Columbia Threadneedle Investments (UK) | 418 024 | 418 024 | 29.02.2024 |
0,54 % | Bridgeway Capital Management, LLC | 379 467 | -225 700 | 31.12.2023 |
0,49 % | Superstring Capital Management LP | 347 381 | 347 381 | 31.12.2023 |
0,48 % | JPMorgan Asset Management U.K. Limited | 337 607 | 0 | 31.12.2023 |
0,42 % | BlackRock Financial Management, Inc. | 293 606 | -20 759 | 31.12.2023 |
0,39 % | Northern Trust Investments, Inc. | 276 431 | -1964 | 31.12.2023 |
0,36 % | Marshall Wace LLP | 250 667 | 250 667 | 31.12.2023 |
0,35 % | Jefferies LLC | 250 000 | 0 | 31.12.2023 |
0,29 % | Stifel, Nicolaus & Company, Incorporated | 207 264 | -319 362 | 31.12.2023 |
0,27 % | Invesco Capital Management LLC | 193 602 | -71 767 | 31.12.2023 |
0,21 % | Two Sigma Investments, LP | 150 645 | 72 545 | 31.12.2023 |
0,21 % | Jane Street Capital, L.L.C. | 146 231 | 146 231 | 31.12.2023 |
0,21 % | Trager (James) | 145 415 | -4143 | 12.02.2024 |
0,20 % | Innovis Asset Management LLC | 138 962 | 138 962 | 30.09.2023 |
0,20 % | Fidelity Management & Research Company LLC | 138 713 | 134 355 | 31.12.2023 |
0,17 % | BofA Global Research (US) | 122 145 | 10 367 | 31.12.2023 |
0,17 % | Hastings (Paul J) | 121 280 | -150 000 | 4.03.2024 |
0,16 % | Parametric Portfolio Associates LLC | 114 991 | -37 906 | 31.12.2023 |
0,16 % | Shook (David M.D.) | 110 980 | 52 448 | 16.01.2024 |
0,15 % | Medical Strategy GmbH | 108 136 | 0 | 30.09.2023 |
0,15 % | Millennium Management LLC | 105 869 | 91 707 | 31.12.2023 |
0,14 % | ACCI Capital Investments SGIIC, SA | 100 000 | -20 000 | 31.12.2023 |
0,14 % | IndexIQ Advisors LLC | 97 660 | -2634 | 31.12.2023 |
0,14 % | BlackRock Investment Management, LLC | 95 616 | -788 | 31.12.2023 |
0,13 % | Morgan Stanley & Co. LLC | 91 581 | 31 351 | 31.12.2023 |
0,13 % | Nuveen LLC | 90 767 | 9374 | 31.12.2023 |
0,13 % | Acadian Asset Management LLC | 90 669 | 26 120 | 31.12.2023 |
0,12 % | Davis (Aaron I) | 84 900 | 84 900 | 8.01.2024 |
0,12 % | BNY Mellon Asset Management | 82 728 | -1093 | 31.12.2023 |
0,12 % | Barclays Bank PLC | 81 139 | 35 997 | 31.12.2023 |
0,11 % | Brandenberger (Ralph Erik) | 79 972 | -1604 | 1.03.2024 |
0,10 % | Charles Schwab Investment Management, Inc. | 69 109 | 0 | 31.12.2023 |
0,09 % | AllianceBernstein L.P. | 66 820 | -4000 | 31.12.2023 |
0,09 % | PGIM Quantitative Solutions LLC | 63 280 | -19 800 | 31.12.2023 |
0,08 % | Goldman Sachs & Company, Inc. | 58 371 | 12 836 | 31.12.2023 |
0,08 % | Dimensional Fund Advisors, L.P. | 56 587 | 32 172 | 31.12.2023 |
0,08 % | Levin (Alyssa) | 56 000 | 56 000 | 4.01.2024 |
0,08 % | Leo Wealth, LLC | 54 848 | 0 | 31.12.2023 |
0,07 % | Hager (Alicia J) | 52 842 | 51 446 | 16.01.2024 |
0,07 % | Rhumbline Advisers Ltd. Partnership | 49 330 | 0 | 31.12.2023 |
0,06 % | Connor, Clark & Lunn Investment Management Ltd. | 45 426 | 30 995 | 31.12.2023 |
0,06 % | Avantis Investors | 45 155 | 18 824 | 31.03.2024 |
0,06 % | Northern Trust Global Investments | 44 318 | 81 | 31.12.2023 |
0,06 % | Dimensional Fund Advisors, Ltd. | 43 054 | 2763 | 31.01.2024 |
0,06 % | T. Rowe Price Japan, Inc. | 39 498 | 39 498 | 31.08.2023 |
0,05 % | Squarepoint Capital LLP | 36 642 | 36 642 | 31.12.2023 |
0,05 % | UBS Financial Services, Inc. | 34 284 | 19 978 | 31.12.2023 |
0,05 % | Amundi Asset Management, SAS | 32 469 | 0 | 31.12.2023 |
0,04 % | Mahmood (Nadir Ahmeduddin) | 30 676 | -526 | 20.06.2023 |
0,04 % | American Century Investment Management, Inc. | 29 348 | 7531 | 31.12.2023 |
0,04 % | Tekla Capital Management LLC_NLE | 28 988 | 0 | 30.06.2023 |
0,04 % | abrdn Inc. | 28 988 | 28 988 | 31.12.2023 |
0,04 % | Denali Advisors, LLC | 26 500 | 26 500 | 31.03.2024 |
0,04 % | DWS Investments UK Limited | 25 401 | 25 401 | 31.12.2023 |
0,03 % | Susquehanna Portfolio Strategies, LLC | 23 411 | 23 411 | 31.12.2023 |
0,03 % | Mellon Investments Corporation | 23 244 | 0 | 31.12.2023 |
0,03 % | State Street Global Advisors Ireland Limited | 23 015 | -84 | 30.04.2023 |
0,03 % | T. Rowe Price International Ltd | 22 502 | 0 | 31.01.2024 |
0,03 % | Holistic Planning, L.L.C. | 21 200 | 21 200 | 31.12.2023 |
0,03 % | Goldman Sachs Asset Management, L.P. | 20 797 | -5166 | 31.12.2023 |
0,03 % | Forefront Analytics, LLC | 20 767 | -18 890 | 31.12.2023 |
0,03 % | Abaris Investment Management AG | 20 000 | 20 000 | 30.06.2023 |
0,03 % | JPMorgan Private Bank (United States) | 19 599 | 19 599 | 31.12.2023 |
0,03 % | HSBC Global Asset Management (UK) Limited | 18 837 | 24 | 31.12.2023 |
0,03 % | Susquehanna International Group, LLP | 18 285 | -236 838 | 31.12.2023 |
0,03 % | Simplex Trading, LLC | 17 877 | 6602 | 31.12.2023 |
0,02 % | Bailard, Inc. | 16 113 | -18 300 | 31.12.2023 |
0,02 % | Principal Global Investors (Equity) | 15 793 | 1288 | 31.12.2023 |
0,02 % | SunAmerica Asset Management, LLC | 15 030 | -61 | 31.12.2023 |
0,02 % | Vanguard Personalized Indexing Management, LLC | 14 226 | 2613 | 31.12.2023 |
0,02 % | Mariner Wealth Advisors | 13 474 | -17 474 | 31.12.2023 |
0,02 % | Sierra Summit Advisors LLC | 11 801 | 11 801 | 31.12.2023 |
0,02 % | Vaughan Nelson Investment Management, L.P. | 11 789 | 0 | 31.12.2023 |
0,02 % | SG Americas Securities, L.L.C. | 10 857 | 10 857 | 31.12.2023 |
0,02 % | Wellington Management Company, LLP | 10 806 | -65 | 29.02.2024 |
0,02 % | Sawtooth Asset Management, Inc. | 10 608 | 10 608 | 31.12.2023 |
0,02 % | Bleakley Financial Group LLC | 10 608 | 10 608 | 31.12.2023 |
0,01 % | Columbia Threadneedle Investments (US) | 10 276 | -127 | 31.12.2023 |
0,01 % | Wells Fargo Bank, N.A. | 9314 | 1840 | 31.12.2023 |
0,01 % | Invesco Advisers, Inc. | 8150 | 8150 | 31.12.2023 |
0,01 % | Morgan Stanley Smith Barney LLC | 7786 | 1701 | 31.12.2023 |