15,30104 % | Antecip Capital, L.L.C. | 7 344 500 | 0 | 15.04.2024 |
9,65486 % | RTW Investments L.P. | 4 634 331 | 141 652 | 30.06.2024 |
7,78180 % | The Vanguard Group, Inc. | 3 735 263 | 1724 | 30.06.2024 |
5,94936 % | BlackRock Institutional Trust Company, N.A. | 2 855 693 | 98 721 | 30.06.2024 |
4,91683 % | Fairmount Funds Management LLC | 2 360 077 | 0 | 30.06.2024 |
3,85997 % | Deep Track Capital LP | 1 852 784 | 548 063 | 30.06.2024 |
2,23592 % | Macquarie Investment Management | 1 073 242 | 372 832 | 30.06.2024 |
2,08333 % | RA Capital Management, LP | 1 000 000 | 0 | 30.06.2024 |
1,98958 % | BVF Partners L.P. | 955 000 | 955 000 | 30.06.2024 |
1,95565 % | Eventide Asset Management, LLC | 938 714 | 592 002 | 30.06.2024 |
1,95521 % | State Street Global Advisors (US) | 938 503 | -213 | 30.06.2024 |
1,84353 % | Geode Capital Management, L.L.C. | 884 895 | 39 488 | 30.06.2024 |
1,63869 % | BofA Global Research (US) | 786 573 | 669 746 | 30.06.2024 |
1,56924 % | Citadel Advisors LLC | 753 237 | -390 407 | 30.06.2024 |
1,54352 % | Alethea Capital Management, LLC | 740 888 | 97 | 30.06.2024 |
1,54129 % | Millennium Management LLC | 739 819 | -1699 | 30.06.2024 |
1,53046 % | Wellington Management Company, LLP | 734 620 | 57 974 | 30.06.2024 |
1,52083 % | Adage Capital Management, L.P. | 730 000 | 215 000 | 30.06.2024 |
1,14389 % | Hood River Capital Management LLC | 549 066 | 28 316 | 30.06.2024 |
1,07611 % | Bellevue Asset Management AG | 516 533 | -168 943 | 30.06.2024 |
1,06127 % | Invesco Advisers, Inc. | 509 411 | 322 829 | 30.06.2024 |
1,03063 % | Fidelity Management & Research Company LLC | 494 703 | 31 361 | 30.06.2024 |
0,99801 % | Point72 Asset Management, L.P. | 479 044 | 100 180 | 30.06.2024 |
0,97381 % | PFM Health Sciences, LP | 467 427 | 0 | 30.06.2024 |
0,95648 % | Perceptive Advisors LLC | 459 111 | -646 230 | 30.06.2024 |
0,87178 % | Coleman (Mark H) | 418 456 | -10 497 | 29.05.2024 |
0,84882 % | Fidelity Institutional Asset Management | 407 433 | 42 225 | 30.06.2024 |
0,84212 % | Norges Bank Investment Management (NBIM) | 404 217 | 209 094 | 30.06.2024 |
0,83333 % | Boxer Capital, L.L.C. | 400 000 | 0 | 30.06.2024 |
0,83333 % | Cormorant Asset Management, LP | 400 000 | 400 000 | 30.06.2024 |
0,78333 % | Avidity Partners Management LP | 376 000 | -55 000 | 30.06.2024 |
0,73575 % | Goldman Sachs & Company, Inc. | 353 158 | 182 848 | 30.06.2024 |
0,70260 % | First Turn Management, LLC | 337 246 | -4927 | 30.06.2024 |
0,66252 % | Woodline Partners LP | 318 011 | -42 117 | 30.06.2024 |
0,64625 % | Sofinnova Investments, Inc | 310 198 | 310 198 | 30.06.2024 |
0,64545 % | Charles Schwab Investment Management, Inc. | 309 818 | 8744 | 30.06.2024 |
0,63857 % | Tri Locum Partners LP | 306 513 | 203 802 | 30.06.2024 |
0,62500 % | Vestal Point Capital, LP | 300 000 | 300 000 | 30.06.2024 |
0,61228 % | Northern Trust Investments, Inc. | 293 894 | -11 187 | 30.06.2024 |
0,60578 % | Checkpoint Capital L.P. | 290 772 | 158 335 | 30.06.2024 |
0,56060 % | Loomis, Sayles & Company, L.P. | 269 089 | -10 702 | 30.06.2024 |
0,42245 % | Morgan Stanley Smith Barney LLC | 202 778 | 20 734 | 30.06.2024 |
0,35159 % | AllianceBernstein L.P. | 168 762 | 88 608 | 30.06.2024 |
0,35090 % | Jane Street Capital, L.L.C. | 168 434 | -30 645 | 30.06.2024 |
0,34931 % | Jeffs (Roger A) | 167 668 | 0 | 15.04.2024 |
0,33118 % | BlackRock Financial Management, Inc. | 158 966 | 1675 | 30.06.2024 |
0,31626 % | JP Morgan Asset Management | 151 806 | -6409 | 30.06.2024 |
0,31250 % | Ghost Tree Capital, LLC | 150 000 | -60 000 | 30.06.2024 |
0,27735 % | U.S. Bancorp Asset Management, Inc. | 133 126 | 421 | 30.09.2024 |
0,27565 % | MPM BioImpact LLC | 132 312 | 18 185 | 30.06.2024 |
0,27186 % | BlackRock Advisors (UK) Limited | 130 494 | 119 | 30.09.2024 |
0,26583 % | Rhenman & Partners Asset Management AB | 127 600 | -16 000 | 30.06.2024 |
0,26417 % | Iridian Asset Management LLC | 126 803 | -102 | 30.09.2024 |
0,26198 % | BlackRock Asset Management Ireland Limited | 125 752 | -13 146 | 30.06.2024 |
0,23614 % | WCM Investment Management | 113 345 | 1755 | 30.06.2024 |
0,22243 % | ClearBridge Investments, LLC | 106 767 | 17 397 | 30.06.2024 |
0,21930 % | Putnam Investment Management, L.L.C. | 105 266 | 941 | 30.06.2024 |
0,21087 % | HSBC Private Bank (Suisse) S.A. | 101 219 | 101 219 | 31.08.2024 |
0,20991 % | Nuveen LLC | 100 757 | -143 532 | 30.06.2024 |
0,20551 % | Eagle Asset Management, Inc. | 98 645 | -127 870 | 30.06.2024 |
0,20006 % | Frontier Capital Management Company, LLC | 96 027 | -9317 | 30.06.2024 |
0,19982 % | BNY Mellon Asset Management | 95 913 | 5278 | 30.06.2024 |
0,19433 % | BlackRock Investment Management, LLC | 93 278 | 6938 | 30.06.2024 |
0,18524 % | Voya Investment Management LLC | 88 915 | 69 628 | 30.06.2024 |
0,18302 % | Artia Global Partners LP | 87 848 | 0 | 30.06.2024 |
0,17613 % | Medical Strategy GmbH | 84 541 | -6849 | 30.06.2024 |
0,17102 % | Cannell & Spears LLC | 82 092 | -638 | 30.06.2024 |
0,17016 % | Wells Fargo Bank, N.A. | 81 677 | 70 990 | 30.06.2024 |
0,16667 % | Affinity Asset Advisors LLC | 80 000 | -59 758 | 30.06.2024 |
0,16388 % | Morgan Stanley & Co. LLC | 78 662 | -444 365 | 30.06.2024 |
0,16060 % | Pictet Asset Management (Japan) Ltd. | 77 087 | 77 087 | 30.04.2024 |
0,15838 % | Walleye Capital LLC | 76 023 | -21 097 | 30.06.2024 |
0,15576 % | Neuberger Berman, LLC | 74 767 | -16 889 | 30.06.2024 |
0,15486 % | Privium Fund Management BV | 74 332 | -7700 | 30.06.2024 |
0,15286 % | Managed Account Advisors LLC | 73 375 | 26 992 | 30.06.2024 |
0,14985 % | Peregrine Capital Management, LLC | 71 929 | -15 444 | 30.09.2024 |
0,14651 % | Lindbrook Capital, LLC | 70 326 | -13 442 | 30.06.2024 |
0,14585 % | SpiderRock Advisors LLC | 70 008 | -11 | 30.06.2024 |
0,14491 % | Scout Investments, Inc. | 69 558 | 35 527 | 30.06.2024 |
0,13226 % | Mellon Investments Corporation | 63 486 | 10 767 | 30.06.2024 |
0,12969 % | DWS Investment Management Americas, Inc. | 62 253 | -884 | 30.06.2024 |
0,12957 % | HighVista Strategies LLC | 62 192 | 13 665 | 30.06.2024 |
0,12634 % | Moody Aldrich Partners, LLC | 60 644 | -1107 | 30.09.2024 |
0,12604 % | Schweizerische Nationalbank | 60 500 | 0 | 30.06.2024 |
0,12323 % | William Blair & Company, L.L.C. (Research) | 59 151 | -4396 | 30.06.2024 |
0,12273 % | Schonfeld Strategic Advisors LLC | 58 909 | -1273 | 30.06.2024 |
0,12146 % | International Biotechnology Trust PLC | 58 300 | 0 | 30.09.2023 |
0,12146 % | Schroder Investment Management Ltd. (SIM) | 58 300 | 0 | 30.06.2024 |
0,12114 % | Hennion & Walsh Asset Management, Inc. | 58 148 | -6537 | 30.09.2024 |
0,11444 % | Rhumbline Advisers Ltd. Partnership | 54 931 | 2674 | 30.06.2024 |
0,10417 % | Altium Capital Management LP | 50 000 | -88 000 | 30.06.2024 |
0,10353 % | Baldwin Brothers, LLC. | 49 695 | 0 | 30.09.2024 |
0,10208 % | Atika Capital Management LLC | 49 000 | -19 000 | 30.06.2024 |
0,10035 % | Goldman Sachs Asset Management, L.P. | 48 169 | -73 133 | 30.06.2024 |
0,09612 % | INVESCO Asset Management Limited | 46 137 | -10 831 | 30.06.2024 |
0,08980 % | Pizzie (Nick) | 43 104 | 827 | 15.04.2024 |
0,08902 % | Columbia Threadneedle Investments (US) | 42 730 | 33 400 | 30.06.2024 |
0,08481 % | WMS Partners LLC | 40 711 | 0 | 30.06.2024 |
0,08463 % | SEI Investments Management Corporation | 40 624 | 4970 | 30.06.2024 |
0,08333 % | Wells Fargo Securities, LLC | 40 000 | 40 000 | 30.06.2024 |