7,47976 % | Avoro Capital Advisors LLC | 5 666 666 | 0 | |
7,28115 % | Fidelity Management & Research Company LLC | 5 516 202 | 505 | |
6,92984 % | Capital Research Global Investors | 5 250 043 | 93 377 | |
5,83352 % | Driehaus Capital Management, LLC | 4 419 472 | 97 732 | |
5,05309 % | Wellington Management Company, LLP | 3 828 221 | −93 837 | |
3,63551 % | Commodore Capital LP | 2 754 266 | 586 473 | |
3,53952 % | Capital World Investors | 2 681 537 | 0 | |
3,37985 % | Braidwell LP | 2 560 573 | 1 252 562 | |
3,34749 % | Polar Capital LLP | 2 536 058 | −76 050 | |
3,26803 % | Capital International Investors | 2 475 859 | 0 | |
2,69704 % | Paradigm BioCapital Advisors LP | 2 043 280 | −441 594 | |
2,42813 % | Adage Capital Management, L.P. | 1 839 555 | 167 638 | |
1,95772 % | AllianceBernstein L.P. | 1 483 166 | 14 720 | |
1,95287 % | Pictet Asset Management Ltd. | 1 479 491 | −35 935 | |
1,90061 % | T. Rowe Price Investment Management, Inc. | 1 439 903 | 13 564 | |
1,82771 % | Marshall Wace LLP | 1 384 674 | −65 668 | |
1,72421 % | First Light Asset Management, LLC | 1 306 260 | −13 912 | |
1,68014 % | Rock Springs Capital Management LP | 1 272 877 | 17 300 | |
1,65255 % | Fidelity Institutional Asset Management | 1 251 971 | 165 838 | |
1,37970 % | Janus Henderson Investors | 1 045 257 | 103 688 | |
1,31234 % | Affinity Asset Advisors LLC | 994 227 | 156 840 | |
1,31161 % | Baker Bros. Advisors LP | 993 679 | 0 | |
1,27979 % | BlackRock Financial Management, Inc. | 969 569 | 46 032 | |
1,13828 % | OrbiMed Advisors, LLC | 862 362 | 312 362 | |
1,02959 % | Invesco Advisers, Inc. | 780 016 | −25 650 | |
1,01469 % | Citadel Advisors LLC | 768 726 | −518 349 | |
0,99590 % | TimesSquare Capital Management, LLC | 754 493 | 17 320 | |
0,99525 % | Avidity Partners Management LP | 754 000 | 44 000 | |
0,99194 % | BlackRock Institutional Trust Company, N.A. | 751 490 | 14 390 | |
0,96958 % | Federated Hermes Global Investment Management Corp. | 734 555 | −345 | |
0,87151 % | Loomis, Sayles & Company, L.P. | 660 258 | −26 252 | |
0,84945 % | Westfield Capital Management Company, L.P. | 643 546 | 296 195 | |
0,84436 % | Samlyn Capital, LLC | 639 685 | 243 489 | |
0,79197 % | Boxer Capital, L.L.C. | 600 000 | 0 | |
0,76987 % | Perceptive Advisors LLC | 583 256 | −308 952 | |
0,75793 % | Fiera Capital Inc. | 574 211 | 3 893 | |
0,75273 % | Jennison Associates LLC | 570 272 | 6 320 | |
0,69298 % | Vestal Point Capital, LP | 525 000 | 125 000 | |
0,68880 % | Candriam Belgium S.A. | 521 836 | −39 048 | |
0,63625 % | Point72 Asset Management, L.P. | 482 022 | 206 163 | |
0,61228 % | Candriam Luxembourg S.A. | 463 861 | 0 | |
0,57611 % | Dimensional Fund Advisors, L.P. | 436 460 | 26 253 | |
0,53330 % | Two Sigma Investments, LP | 404 029 | −99 797 | |
0,50694 % | BNP Paribas Asset Management USA, Inc. | 384 058 | 2 605 | |
0,50364 % | Invus Public Equities Advisors, LLC | 381 554 | 128 167 | |
0,49498 % | Logos Global Management LLC | 375 000 | 375 000 | |
0,48288 % | Norges Bank Investment Management (NBIM) | 365 830 | 231 372 | |
0,47598 % | Altium Capital Management LP | 360 600 | 12 600 | |
0,47146 % | ExodusPoint Capital Management, LP | 357 178 | 203 140 | |
0,44862 % | First Turn Management, LLC | 339 876 | −340 513 | |
0,43878 % | Goldman Sachs & Company, Inc. | 332 421 | 62 757 | |
0,43313 % | The Vanguard Group, Inc. | 328 143 | 5 517 | |
0,42414 % | Medical Strategy GmbH | 321 332 | −4 600 | |
0,38784 % | Franklin Advisers, Inc. | 293 825 | 0 | |
0,38525 % | Alyeska Investment Group, L.P. | 291 868 | 53 025 | |
0,37624 % | Putnam Investment Management, L.L.C. | 285 040 | 36 576 | |
0,36132 % | Dafna Capital Management, LLC | 273 739 | 0 | |
0,33060 % | Boone Capital Management LLC | 250 460 | −40 943 | |
0,32776 % | abrdn Inc. | 248 311 | 35 809 | |
0,32578 % | State Street Global Advisors (US) | 246 812 | 4 172 | |
0,30799 % | Balyasny Asset Management LP | 233 335 | 32 061 | |
0,29853 % | Granahan Investment Management, LLC | 226 166 | −17 914 | |
0,29710 % | Morgan Stanley & Co. LLC | 225 082 | −141 640 | |
0,28021 % | Assenagon Asset Management S.A. | 212 287 | 138 685 | |
0,27625 % | Parkman Healthcare Partners LLC | 209 290 | −14 652 | |
0,25084 % | Lord, Abbett & Co. LLC | 190 033 | −705 163 | |
0,24820 % | AXA Investment Managers UK Ltd. | 188 038 | 166 | |
0,24182 % | Algert Global LLC | 183 205 | −810 | |
0,23196 % | DNB Asset Management AS | 175 733 | 49 483 | |
0,23176 % | Millennium Management LLC | 175 584 | 91 923 | |
0,22597 % | Laurion Capital Management LP | 171 195 | −67 931 | |
0,22405 % | BlackRock Investment Management (UK) Ltd. | 169 738 | 54 944 | |
0,22356 % | Ally Bridge Group NY LLC | 169 369 | −140 000 | |
0,21524 % | Ensign Peak Advisors, Inc. | 163 064 | 0 | |
0,21347 % | D. E. Shaw & Co., L.P. | 161 722 | −36 804 | |
0,21268 % | BlackRock Advisors (UK) Limited | 161 124 | 1 456 | |
0,20880 % | Russell Investments Trust Company | 158 185 | −15 021 | |
0,19931 % | Nomura Asset Management Co., Ltd. | 151 000 | −34 400 | |
0,19872 % | PFM Health Sciences, LP | 150 554 | 0 | |
0,19377 % | Bridger Management, LLC | 146 800 | 0 | |
0,18052 % | BlackRock Asset Management Ireland Limited | 136 761 | −155 554 | |
0,17492 % | New York State Common Retirement Fund | 132 521 | −18 319 | |
0,16645 % | Schweizerische Nationalbank | 126 100 | 2 300 | |
0,16367 % | Atika Capital Management LLC | 124 000 | 2 000 | |
0,14900 % | Polen Capital Management, LLC | 112 881 | 25 782 | |
0,14526 % | Tenax Capital Ltd. | 110 047 | 0 | |
0,14148 % | Ikarian Capital LLC | 107 187 | 0 | |
0,14081 % | Nan Fung Life Sciences | 106 680 | 0 | |
0,13458 % | Tri Locum Partners LP | 101 959 | −105 506 | |
0,13213 % | Baron Capital Management, Inc. | 100 100 | 0 | |
0,12759 % | Principal Global Investors (Equity) | 96 662 | −6 920 | |
0,12262 % | Renaissance Technologies LLC | 92 900 | 36 500 | |
0,12078 % | Schroder Investment Management Ltd. (SIM) | 91 500 | 0 | |
0,12078 % | International Biotechnology Trust PLC | 91 500 | 66 000 | |
0,11853 % | State of Wisconsin Investment Board | 89 800 | −1 985 | |
0,11709 % | TwinBeech Capital LP | 88 711 | −9 331 | |
0,11651 % | MFS Investment Management | 88 267 | −704 | |
0,11163 % | New Jersey Division of Investment | 84 573 | −8 177 | |
0,10956 % | Victory Capital Management Inc. | 82 999 | −14 354 | |
0,09890 % | Neuberger Berman, LLC | 74 926 | 12 896 | |