9,38208 % | ARK Investment Management LLC | 11 357 011 | 2 043 248 | |
9,37082 % | Fidelity Management & Research Company LLC | 11 343 373 | −161 729 | |
9,06479 % | The Vanguard Group, Inc. | 10 972 930 | 804 722 | |
5,07482 % | Nikko Asset Management Co., Ltd. | 6 143 067 | 2 521 289 | |
4,16573 % | BlackRock Institutional Trust Company, N.A. | 5 042 621 | 221 683 | |
3,25595 % | Morgan Stanley Investment Management Inc. (US) | 3 941 332 | 360 754 | |
2,38303 % | Generation Investment Management LLP | 2 884 661 | 1 470 537 | |
2,28733 % | T. Rowe Price Associates, Inc. | 2 768 813 | −783 819 | |
2,26531 % | Baillie Gifford & Co. | 2 742 153 | −34 962 | |
2,05180 % | Brown Capital Management, LLC | 2 483 705 | −191 142 | |
1,92887 % | Sands Capital Management, LLC | 2 334 901 | −1 048 240 | |
1,78685 % | T. Rowe Price Investment Management, Inc. | 2 162 979 | −41 451 | |
1,74040 % | VR Management, L.L.C. | 2 106 757 | 0 | |
1,46463 % | Geode Capital Management, L.L.C. | 1 772 933 | 129 780 | |
1,43200 % | UBS Asset Management (UK) Ltd. | 1 733 441 | 1 697 382 | |
1,37723 % | Fidelity Institutional Asset Management | 1 667 136 | 242 989 | |
1,34995 % | State Street Global Advisors (US) | 1 634 109 | 48 407 | |
1,18963 % | Voloridge Investment Management, LLC | 1 440 042 | 538 297 | |
1,12412 % | Millennium Management LLC | 1 360 751 | 228 323 | |
0,81871 % | Norges Bank Investment Management (NBIM) | 991 051 | 343 055 | |
0,80752 % | Saxonov (Serge Wilson) | 977 504 | −6 749 | |
0,79693 % | Charles Schwab Investment Management, Inc. | 964 682 | 20 325 | |
0,71987 % | Morgan Stanley & Co. LLC | 871 408 | 99 168 | |
0,65535 % | Capital World Investors | 793 300 | 0 | |
0,65535 % | Capital Research Global Investors | 793 300 | 0 | |
0,62637 % | BlackRock Financial Management, Inc. | 758 217 | 96 227 | |
0,59397 % | Soleus Capital Management, L.P. | 719 000 | 719 000 | |
0,58532 % | Foresite Capital Management, LLC | 708 528 | 0 | |
0,51219 % | Qube Research & Technologies Ltd | 620 002 | 236 298 | |
0,49318 % | Deerfield Management Company, L.P. | 597 000 | 597 000 | |
0,47944 % | BofA Global Research (US) | 580 360 | 59 278 | |
0,42964 % | Barclays Bank PLC | 520 082 | 464 625 | |
0,42617 % | Squarepoint Capital LLP | 515 883 | 5 720 | |
0,42573 % | New York State Common Retirement Fund | 515 348 | −49 790 | |
0,41657 % | SRS Investment Management, LLC | 504 257 | 504 257 | |
0,41541 % | RTW Investments L.P. | 502 856 | −1 052 000 | |
0,40829 % | Meritech Capital Partners | 494 236 | 0 | |
0,39799 % | Sands Capital Ventures LLC | 481 770 | 0 | |
0,38586 % | Boston Management and Research | 467 079 | 0 | |
0,38085 % | Granite Investment Partners, LLC | 461 013 | −48 020 | |
0,37013 % | Northern Trust Investments, Inc. | 448 040 | 76 009 | |
0,34351 % | Roberts (Bryan E) | 415 815 | 1 865 | |
0,33044 % | Southpoint Capital Advisors LP | 400 000 | −300 000 | |
0,29581 % | Two Sigma Investments, LP | 358 077 | 292 225 | |
0,29265 % | Stuelpnagel (John R) | 354 250 | 8 649 | |
0,27624 % | Citadel Advisors LLC | 334 393 | 247 234 | |
0,27592 % | Granahan Investment Management, LLC | 334 007 | 155 114 | |
0,27173 % | Trexquant Investment LP | 328 924 | −33 495 | |
0,26608 % | Parametric Portfolio Associates LLC | 322 084 | 121 814 | |
0,26037 % | AQR Capital Management, LLC | 315 180 | 219 945 | |
0,26011 % | Baron Capital Management, Inc. | 314 862 | 0 | |
0,25470 % | Bellevue Asset Management AG | 308 311 | 0 | |
0,23892 % | ExodusPoint Capital Management, LP | 289 211 | 123 479 | |
0,23508 % | TD Asset Management Inc. | 284 564 | −95 000 | |
0,21794 % | Nuveen LLC | 263 811 | 15 527 | |
0,21634 % | PDT Partners, LLC | 261 880 | 216 662 | |
0,19507 % | Tudor Investment Corporation | 236 130 | 154 518 | |
0,19459 % | Goldman Sachs Asset Management, L.P. | 235 547 | −50 599 | |
0,19000 % | Blue Water Life Science Advisors, LP. | 230 000 | 35 500 | |
0,18335 % | BlackRock Asset Management Ireland Limited | 221 943 | −31 959 | |
0,17769 % | Dimensional Fund Advisors, L.P. | 215 092 | −261 145 | |
0,17365 % | Renaissance Technologies LLC | 210 200 | 157 800 | |
0,16660 % | Susquehanna Fundamental Investments, LLC | 201 671 | 126 052 | |
0,16658 % | BlackRock Investment Management (UK) Ltd. | 201 642 | 92 050 | |
0,16172 % | Magnetar Capital Partners LP | 195 762 | 105 500 | |
0,15851 % | Northern Trust Global Investments | 191 882 | −19 061 | |
0,15679 % | Jane Street Capital, L.L.C. | 189 792 | 174 938 | |
0,15558 % | Vestmark Advisory Solutions, Inc | 188 327 | 32 284 | |
0,15456 % | Schweizerische Nationalbank | 187 100 | 12 400 | |
0,15432 % | PRIMECAP Management Company | 186 800 | 107 400 | |
0,14965 % | Osaic Holdings, Inc. | 181 148 | 157 386 | |
0,14891 % | Mammen (Mathai) | 180 259 | 8 649 | |
0,14078 % | Mellon Investments Corporation | 170 417 | −378 379 | |
0,14044 % | Harvard Management Company, Inc. | 170 000 | 0 | |
0,12940 % | Whitaker (Eric S) | 156 639 | 31 975 | |
0,12762 % | Armistice Capital LLC | 154 482 | −3 804 | |
0,12445 % | UBS Financial Services, Inc. | 150 647 | 96 380 | |
0,12404 % | Managed Account Advisors LLC | 150 155 | 35 917 | |
0,12034 % | California Public Employees' Retirement System | 145 667 | 24 450 | |
0,11974 % | Russell Investments Trust Company | 144 948 | 184 | |
0,11837 % | Morgan Stanley Smith Barney LLC | 143 292 | 23 941 | |
0,11716 % | Manulife Investment Management (North America) Limited | 141 823 | −15 092 | |
0,11707 % | Mirae Asset Global Investments (USA) LLC | 141 713 | −177 574 | |
0,11428 % | BNY Mellon Asset Management | 138 332 | −25 061 | |
0,10878 % | American Century Investment Management, Inc. | 131 683 | −36 547 | |
0,09851 % | Putnam Investment Management, L.L.C. | 119 251 | 43 004 | |
0,09745 % | Algert Global LLC | 117 964 | 33 364 | |
0,09611 % | Slow Capital, Inc. | 116 340 | 10 814 | |
0,08837 % | Rhumbline Advisers Ltd. Partnership | 106 972 | 65 | |
0,08686 % | T. Rowe Price International Ltd | 105 139 | 544 | |
0,08588 % | IEQ Capital LLC | 103 958 | −27 283 | |
0,08555 % | Numeric Investors LLC | 103 556 | 58 991 | |
0,08369 % | Jacobs Levy Equity Management, Inc. | 101 301 | 4 129 | |
0,08306 % | Legal & General Investment Management Ltd. | 100 544 | 15 587 | |
0,07869 % | CIBC Asset Management Inc. | 95 259 | 23 112 | |
0,07720 % | California State Teachers Retirement System | 93 456 | 4 532 | |
0,07545 % | HSBC Global Asset Management (UK) Limited | 91 335 | 91 335 | |
0,07524 % | Susquehanna International Group, LLP | 91 081 | 53 219 | |
0,07413 % | Florida State Board of Administration | 89 738 | 0 | |
0,07299 % | Aperio Group, LLC | 88 359 | 7 350 | |