37,59532 % | Tang Capital Management, LLC | 9 607 934 | −240 000 | |
9,10700 % | RTW Investments L.P. | 2 327 403 | −500 | |
4,94988 % | Healthinvest Partners AB | 1 265 000 | 558 000 | |
3,23006 % | The Vanguard Group, Inc. | 825 481 | −3 962 | |
2,69831 % | Medical Strategy GmbH | 689 585 | −58 567 | |
2,34804 % | D. E. Shaw & Co., L.P. | 600 070 | 11 268 | |
1,86917 % | Acadian Asset Management LLC | 477 688 | 42 301 | |
1,60509 % | BlackRock Institutional Trust Company, N.A. | 410 200 | −1 919 | |
1,37736 % | Tang (Kevin C) | 352 000 | 112 000 | |
1,01610 % | Norges Bank Investment Management (NBIM) | 259 676 | 259 676 | |
0,79361 % | Geode Capital Management, L.L.C. | 202 816 | −81 054 | |
0,54346 % | Millennium Management LLC | 138 889 | −612 | |
0,39129 % | Ramsay (David) | 100 000 | 52 000 | |
0,38715 % | State Street Global Advisors (US) | 98 941 | 3 962 | |
0,36312 % | GlobeFlex Capital, L.P. | 92 799 | 0 | |
0,35389 % | Fidelity Management & Research Company LLC | 90 441 | 90 441 | |
0,31442 % | Hollencrest Capital Management | 80 355 | −2 000 | |
0,30555 % | Northern Trust Investments, Inc. | 78 088 | 4 047 | |
0,24434 % | Two Sigma Investments, LP | 62 444 | −86 068 | |
0,22812 % | Newton Investment Management North America, LLC | 58 300 | 0 | |
0,22535 % | Mellon Investments Corporation | 57 590 | 5 781 | |
0,19906 % | Citadel Advisors LLC | 50 873 | −11 104 | |
0,16329 % | First Midwest Trust Company | 41 731 | 0 | |
0,16154 % | Old National Wealth Management | 41 284 | 41 284 | |
0,13160 % | O'Shaughnessy Asset Management, LLC | 33 632 | 33 632 | |
0,11377 % | Los Angeles Capital Management And Equity Research, Inc. | 29 075 | 22 175 | |
0,10213 % | Schonfeld Strategic Advisors LLC | 26 100 | 10 400 | |
0,10213 % | Renaissance Technologies LLC | 26 100 | −9 400 | |
0,09939 % | Axiom Asset Management | 25 400 | 0 | |
0,09699 % | Morgan Stanley Smith Barney LLC | 24 788 | 81 | |
0,07543 % | Morgan Stanley & Co. LLC | 19 277 | −23 692 | |
0,06541 % | Ritholtz Wealth Management LLC | 16 716 | 1 685 | |
0,05368 % | Goldman Sachs Asset Management, L.P. | 13 718 | −301 | |
0,05299 % | Occudo Quantitative Strategies LP | 13 541 | −3 635 | |
0,04696 % | Johnson (Craig A) | 12 000 | 12 000 | |
0,04683 % | Edwards (Larry G) | 11 969 | 296 | |
0,04518 % | Susquehanna International Group, LLP | 11 546 | −36 | |
0,04380 % | BNY Mellon Asset Management | 11 194 | 0 | |
0,04031 % | BlackRock Financial Management, Inc. | 10 301 | 0 | |
0,03986 % | Hearne (Michael S.) | 10 186 | 472 | |
0,03913 % | Running Point Capital Advisors, LLC | 10 000 | 10 000 | |
0,02739 % | PNC Wealth Management | 7 000 | 0 | |
0,02579 % | BofA Global Research (US) | 6 592 | −7 564 | |
0,02387 % | Apo Asset Management GmbH | 6 100 | −18 012 | |
0,02094 % | Barclays Bank PLC | 5 352 | −12 | |
0,01687 % | Meeder Asset Management, Inc | 4 312 | 4 312 | |
0,01397 % | Tower Research Capital LLC | 3 569 | −5 183 | |
0,01349 % | BlackRock Investment Management, LLC | 3 447 | −309 | |
0,01349 % | Lord, Abbett & Co. LLC | 3 447 | 0 | |
0,01096 % | Ellis Investment Partners, LLC | 2 800 | 0 | |
0,01004 % | BlackRock Japan Co., Ltd. | 2 565 | −28 | |
0,00959 % | Wells Fargo Advisors | 2 451 | −2 500 | |
0,00868 % | UBS Financial Services, Inc. | 2 218 | −2 209 | |
0,00769 % | Northern Trust Global Investments | 1 965 | 0 | |
0,00409 % | Seasons of Advice Wealth Management | 1 045 | 0 | |
0,00232 % | Group One Trading, L.P. | 594 | −7 533 | |
0,00196 % | Johnson (Laura Laura) | 500 | 0 | |
0,00196 % | Tyler-Stone Wealth Management LLC | 500 | 0 | |
0,00133 % | J.P. Morgan Securities LLC | 341 | −1 163 | |
0,00129 % | Simplex Trading, LLC | 330 | −1 758 | |
0,00088 % | RBC Private Counsel (USA) Inc. | 225 | 0 | |
0,00078 % | Blackstone Alternative Investment Advisors LLC | 200 | 0 | |
0,00063 % | Wells Fargo Bank, N.A. | 161 | 1 | |
0,00018 % | J.P. Morgan Securities plc | 47 | 0 | |
0,00000 % | BNP Paribas Securities Corp. North America | 1 | −30 733 | |
0 % | ExodusPoint Capital Management, LP | 0 | −10 073 | |
0 % | Ergoteles Capital | 0 | −57 083 | |
0 % | Summit Global Investments, LLC | 0 | −48 500 | |
0 % | Ellevest, Inc. | 0 | −41 | |
0 % | L2 Asset Management, LLC | 0 | −15 | |
0 % | Squarepoint Capital LLP | 0 | −13 227 | |
0 % | Advisor Group, Inc | 0 | −1 150 | |
0 % | Powell Investment Advisors, LLC | 0 | −12 000 | |
0 % | Engineers Gate Manager, L.P. | 0 | −16 400 | |
0 % | Trexquant Investment LP | 0 | −25 006 | |
0 % | HRT Financial LP | 0 | −45 461 | |
0 % | Cubist Systematic Strategies, LLC | 0 | −16 218 | |
0 % | PDT Partners, LLC | 0 | −10 585 | |
0 % | Tibra Equities Europe, Ltd. | 0 | −72 600 | |
0 % | LMR Partners LLP | 0 | −11 515 | |
0 % | Principal Funds, Inc. | 0 | −2 623 | |
0 % | Quantbot Technologies, LP | 0 | −495 | |
0 % | HighVista Strategies LLC | 0 | −25 493 | |
0 % | DWS Investments UK Limited | 0 | −11 709 | |
0 % | Assenagon Asset Management S.A. | 0 | −401 | |
0 % | Boxer Capital, L.L.C. | 0 | −890 700 | |
0 % | Virtu Americas LLC | 0 | −21 258 | |
0 % | Signaturefd, LLC | 0 | −10 000 | |
0 % | Alyeska Investment Group, L.P. | 0 | −536 847 | |
0 % | ProShare Advisors LLC | 0 | −5 011 | |
0 % | Premier Asset Management, LLC | 0 | −51 305 | |
0 % | CAPTRUST Financial Advisors | 0 | −2 600 | |
0 % | Grimes & Company, Inc. | 0 | −25 270 | |
0 % | GSA Capital Partners LLP | 0 | −26 143 | |
0 % | Broadfin Capital, L.L.C. | 0 | −2 688 068 | |
0 % | Jane Street Capital, L.L.C. | 0 | −35 924 | |
0 % | Aperio Group, LLC | 0 | −15 | |
0 % | Barclays Capital Inc. | 0 | −1 982 | |
0 % | Morgan Stanley & Co. International Plc | 0 | −493 | |
0 % | RBC Capital Partners | 0 | −4 185 | |