10,62690 % | Fidelity Management & Research Company LLC | 16 023 239 | 1 455 424 | |
9,68647 % | MVM Partners LLP | 14 605 263 | 0 | |
9,10406 % | Great Point Partners, LLC | 13 727 097 | 4 940 779 | |
8,89955 % | Nantahala Capital Management, LLC | 13 418 740 | 10 944 444 | |
5,49642 % | Rosalind Advisors, Inc. | 8 287 503 | 740 355 | |
4,83486 % | Kruttschnitt (Theodore H III) | 7 290 000 | 474 211 | |
4,49586 % | Acorn Bioventures L.P. | 6 778 851 | 407 388 | |
3,71351 % | Kingdon Capital Management, L.L.C. | 5 599 237 | 1 700 000 | |
3,31609 % | D. E. Shaw & Co., L.P. | 5 000 000 | 5 000 000 | |
2,98448 % | BlackRock Financial Management, Inc. | 4 500 000 | 4 322 013 | |
2,68280 % | Bleichroeder LP | 4 045 132 | 0 | |
2,55627 % | The Vanguard Group, Inc. | 3 854 345 | −388 265 | |
1,93680 % | MFS Investment Management | 2 920 309 | 81 233 | |
1,65329 % | Velan Capital Investment Management LP | 2 492 830 | −508 361 | |
1,55857 % | Stonepine Capital Management, LLC | 2 350 010 | 2 350 010 | |
1,48974 % | Easterly Investment Partners LLC | 2 246 224 | 208 185 | |
0,75648 % | Rice Hall James & Associates, LLC | 1 140 626 | 152 435 | |
0,73664 % | GMT Capital Corp. | 1 110 702 | 1 110 702 | |
0,71338 % | Millennium Management LLC | 1 075 640 | 744 954 | |
0,64426 % | Geode Capital Management, L.L.C. | 971 415 | −599 245 | |
0,63523 % | Miller (Peter K) | 957 797 | 170 382 | |
0,51934 % | Prescott Group Capital Management, LLC | 783 065 | −56 502 | |
0,50385 % | BlackRock Institutional Trust Company, N.A. | 759 698 | −3 174 305 | |
0,39157 % | Northern Trust Investments, Inc. | 590 403 | 17 740 | |
0,24902 % | Jane Street Capital, L.L.C. | 375 471 | 375 471 | |
0,23876 % | Prelude Capital Management, LLC | 360 000 | 0 | |
0,23678 % | Mahmoud (Ramy A) | 357 023 | −4 881 | |
0,19817 % | State Street Global Advisors (US) | 298 803 | −1 064 129 | |
0,18376 % | Goldman Sachs & Company, Inc. | 277 069 | 204 150 | |
0,15469 % | Susquehanna International Group, LLP | 233 235 | 233 235 | |
0,15460 % | Renaissance Technologies LLC | 233 100 | −48 800 | |
0,14465 % | Bridgeway Capital Management, LLC | 218 100 | −120 000 | |
0,13671 % | UBS Asset Management (Americas), Inc. | 206 134 | 0 | |
0,11381 % | Squarepoint Capital LLP | 171 610 | 108 903 | |
0,10883 % | Newton Investment Management North America, LLC | 164 100 | 0 | |
0,10672 % | Verition Fund Management LLC | 160 908 | 160 908 | |
0,09948 % | Kohler (Terry) | 150 000 | 150 000 | |
0,09852 % | Qube Research & Technologies Ltd | 148 551 | 148 551 | |
0,09054 % | Krick (Anthony J) | 136 519 | −6 845 | |
0,08701 % | Centiva Capital, LP | 131 200 | 131 200 | |
0,07856 % | Marino (Michael F III) | 118 460 | −3 226 | |
0,06632 % | Brown Brothers Harriman & Company | 100 000 | 0 | |
0,05624 % | Y-Intercept (Hong Kong) Ltd | 84 806 | 84 806 | |
0,05604 % | XTX Markets LLC | 84 504 | 84 504 | |
0,05514 % | Paloma Partners Management Company | 83 141 | 83 141 | |
0,05424 % | Alpine Global Management, LLC | 81 782 | 81 782 | |
0,05198 % | Palumbo Wealth Management LLC | 78 378 | −57 153 | |
0,04978 % | Morgan Stanley Smith Barney LLC | 75 061 | 7 525 | |
0,04724 % | Barclays Bank PLC | 71 230 | −29 557 | |
0,04586 % | HRT Financial LP | 69 146 | 69 146 | |
0,03166 % | Northern Trust Global Investments | 47 730 | 0 | |
0,03164 % | Morgan Stanley & Co. LLC | 47 709 | −52 428 | |
0,02958 % | PGIM Quantitative Solutions LLC | 44 600 | 8 160 | |
0,02590 % | Citadel Advisors LLC | 39 048 | −64 425 | |
0,02482 % | Mirae Asset Global Investments (USA) LLC | 37 421 | 37 420 | |
0,02399 % | Charles Schwab Investment Management, Inc. | 36 174 | −166 635 | |
0,02392 % | Invesco Capital Management LLC | 36 074 | 34 810 | |
0,02383 % | SunAmerica Asset Management, LLC | 35 933 | −310 | |
0,02140 % | Citi Investment Research (US) | 32 273 | 22 105 | |
0,02053 % | Goldman Sachs Asset Management, L.P. | 30 951 | −21 168 | |
0,02005 % | Hightower Advisors, LLC | 30 235 | 0 | |
0,01988 % | HSBC Global Asset Management (UK) Limited | 29 979 | −306 | |
0,01887 % | FreeGulliver LLC | 28 450 | 18 000 | |
0,01758 % | Schonfeld Strategic Advisors LLC | 26 500 | 26 500 | |
0,01658 % | HighMark Wealth Management LLC | 25 000 | 0 | |
0,01563 % | Tower Research Capital LLC | 23 574 | 18 109 | |
0,01373 % | Engineers Gate Manager, L.P. | 20 695 | 20 695 | |
0,01233 % | BNY Mellon Asset Management | 18 584 | −133 796 | |
0,01004 % | BofA Global Research (US) | 15 138 | 4 392 | |
0,00964 % | Victory Capital Management Inc. | 14 533 | 3 994 | |
0,00956 % | BlackRock Investment Management, LLC | 14 416 | −156 866 | |
0,00826 % | Jump Financial, LLC | 12 449 | 12 449 | |
0,00819 % | Legato Capital Management LLC | 12 356 | 2 | |
0,00809 % | Mariner Wealth Advisors | 12 203 | −474 | |
0,00798 % | Tradition Wealth Management, LLC | 12 037 | 12 037 | |
0,00693 % | Virtu Americas LLC | 10 456 | 10 456 | |
0,00663 % | Arete Wealth Advisors, LLC | 10 000 | 10 000 | |
0,00663 % | Truist Bank | 10 000 | 10 000 | |
0,00600 % | Rhumbline Advisers Ltd. Partnership | 9 054 | −85 031 | |
0,00533 % | Mackenzie Investments | 8 036 | −8 | |
0,00530 % | Parametric Portfolio Associates LLC | 7 984 | −5 636 | |
0,00343 % | Russell Investments Trust Company | 5 171 | 190 | |
0,00337 % | J.P. Morgan Securities LLC | 5 078 | −88 737 | |
0,00315 % | T. Rowe Price Associates, Inc. | 4 747 | 0 | |
0,00267 % | Metropolitan Life Insurance Co. (US) | 4 030 | 4 030 | |
0,00243 % | Macquarie Investment Management Global Ltd. | 3 671 | 3 671 | |
0,00199 % | Adar1 Capital Management LLC | 3 000 | 3 000 | |
0,00194 % | Morgan Stanley & Co. International Plc | 2 921 | 2 579 | |
0,00126 % | BNP Paribas Securities Corp. North America | 1 907 | −176 606 | |
0,00115 % | J.P. Morgan Securities plc | 1 734 | 0 | |
0,00106 % | UBS Financial Services, Inc. | 1 598 | −71 643 | |
0,00099 % | National Bank of Canada | 1 500 | 0 | |
0,00075 % | JP Morgan Asset Management | 1 133 | −2 073 | |
0,00065 % | ProFund Advisors LLC | 981 | −613 | |
0,00041 % | Morgan Stanley Investment Management Inc. (US) | 615 | 76 | |
0,00031 % | Wells Fargo Advisors | 465 | 215 | |
0,00011 % | SRS Capital Advisors, Inc | 168 | 168 | |
0,00007 % | RBC Dominion Securities, Inc. | 100 | −3 000 | |
0,00002 % | RBC Capital Markets Wealth Management | 33 | 0 | |
0,00001 % | Farther Finance Advisors, LLC | 8 | 0 | |