8,52124 % | The Vanguard Group, Inc. | 11 249 738 | 228 533 | |
4,43318 % | BlackRock Institutional Trust Company, N.A. | 5 852 690 | 319 757 | |
4,00706 % | JP Morgan Asset Management | 5 290 125 | −396 415 | |
3,98626 % | Fred Alger Management, LLC | 5 262 664 | −1 284 263 | |
3,37870 % | Farallon Capital Management, L.L.C. | 4 460 557 | 532 874 | |
2,70625 % | State Street Global Advisors (US) | 3 572 796 | 849 803 | |
2,30866 % | Citadel Advisors LLC | 3 047 899 | 706 288 | |
1,96434 % | RTW Investments L.P. | 2 593 323 | 0 | |
1,82242 % | Invesco Advisers, Inc. | 2 405 957 | −637 233 | |
1,81433 % | MFS Investment Management | 2 395 283 | 147 950 | |
1,72073 % | Rabinowitz (Matthew) | 2 271 708 | 190 000 | |
1,52792 % | Columbia Threadneedle Investments (US) | 2 017 159 | 12 093 | |
1,52584 % | Kynam Capital Management LP | 2 014 408 | 14 408 | |
1,49589 % | Duquesne Family Office LLC | 1 974 880 | 45 500 | |
1,49502 % | Lord, Abbett & Co. LLC | 1 973 722 | 177 412 | |
1,47452 % | Geode Capital Management, L.L.C. | 1 946 655 | 105 098 | |
1,44401 % | AllianceBernstein L.P. | 1 906 384 | −713 075 | |
1,26811 % | Millennium Management LLC | 1 674 165 | −965 089 | |
1,17428 % | Sofinnova Investments, Inc | 1 550 280 | 0 | |
1,09676 % | Samlyn Capital, LLC | 1 447 946 | −536 633 | |
1,05886 % | American Century Investment Management, Inc. | 1 397 912 | −429 691 | |
1,04830 % | Gilder Gagnon Howe & Co. LLC | 1 383 970 | 353 496 | |
0,99765 % | Norges Bank Investment Management (NBIM) | 1 317 102 | −23 412 | |
0,99684 % | Botha (Roelof Frederick) | 1 316 027 | 203 | |
0,93134 % | Allspring Global Investments, LLC | 1 229 558 | 246 246 | |
0,92468 % | Driehaus Capital Management, LLC | 1 220 768 | 155 802 | |
0,88888 % | Eversept Partners, LP | 1 173 494 | −604 557 | |
0,86757 % | D. E. Shaw & Co., L.P. | 1 145 362 | 303 905 | |
0,82686 % | Frontier Capital Management Company, LLC | 1 091 616 | −52 717 | |
0,81074 % | Maverick Capital, Ltd. | 1 070 339 | 271 657 | |
0,80380 % | Charles Schwab Investment Management, Inc. | 1 061 171 | 26 626 | |
0,74515 % | Principal Global Investors (Equity) | 983 747 | −392 666 | |
0,72594 % | Marshall Wace LLP | 958 383 | 334 630 | |
0,69443 % | Wellington Management Company, LLP | 916 782 | −227 126 | |
0,68439 % | Goldman Sachs Asset Management, L.P. | 903 531 | 334 673 | |
0,67761 % | Castle Hook Partners LP | 894 585 | 736 073 | |
0,65198 % | Voya Investment Management LLC | 860 740 | −48 064 | |
0,58152 % | Franklin Advisers, Inc. | 767 724 | 322 719 | |
0,58093 % | First Trust Advisors L.P. | 766 944 | −363 628 | |
0,58059 % | Avidity Partners Management LP | 766 500 | −36 800 | |
0,57283 % | Jennison Associates LLC | 756 252 | 284 105 | |
0,56554 % | Fidelity Management & Research Company LLC | 746 625 | −55 119 | |
0,54854 % | Eagle Asset Management, Inc. | 724 178 | 724 178 | |
0,52075 % | OrbiMed Advisors, LLC | 687 500 | −211 931 | |
0,50178 % | Columbia Threadneedle Investments (UK) | 662 451 | 20 775 | |
0,49350 % | AQR Capital Management, LLC | 651 523 | 469 327 | |
0,45803 % | Mellon Investments Corporation | 604 695 | 32 027 | |
0,44937 % | Columbia Wanger Asset Management, LLC | 593 254 | −151 096 | |
0,42736 % | Summit Partners Public Asset Management, LLC | 564 205 | −58 293 | |
0,42565 % | Point72 Asset Management, L.P. | 561 939 | 298 193 | |
0,42411 % | Two Sigma Investments, LP | 559 915 | 518 714 | |
0,40227 % | Parametric Portfolio Associates LLC | 531 077 | −75 649 | |
0,40145 % | Perceptive Advisors LLC | 530 000 | −227 225 | |
0,39232 % | Nikko Asset Management Co., Ltd. | 517 941 | 146 670 | |
0,38771 % | Pictet Asset Management Ltd. | 511 861 | −74 907 | |
0,38599 % | Morgan Stanley & Co. LLC | 509 584 | 163 422 | |
0,38107 % | Blue Water Life Science Advisors, LP. | 503 094 | 0 | |
0,37276 % | Nuveen LLC | 492 117 | −659 464 | |
0,36795 % | Zevenbergen Capital Investments LLC | 485 772 | −1 859 | |
0,36138 % | Amundi Asset Management US, Inc. | 477 100 | −21 876 | |
0,35912 % | Eagle Health Investments LP | 474 114 | −158 600 | |
0,35621 % | Northern Trust Investments, Inc. | 470 265 | 23 615 | |
0,34767 % | T. Rowe Price Associates, Inc. | 458 991 | −146 061 | |
0,33101 % | Qube Research & Technologies Ltd | 436 993 | 345 550 | |
0,32434 % | UBS Asset Management (UK) Ltd. | 428 192 | 377 834 | |
0,32108 % | Chevy Chase Trust Company | 423 889 | 265 706 | |
0,31461 % | ARK Investment Management LLC | 415 342 | 92 958 | |
0,30910 % | Sheena (Jonathan) | 408 080 | −2 367 | |
0,30027 % | Capital Research Global Investors | 396 421 | 0 | |
0,30027 % | Capital World Investors | 396 421 | 0 | |
0,29563 % | JPMorgan Asset Management U.K. Limited | 390 297 | −453 834 | |
0,29031 % | Federated Hermes Global Investment Management Corp. | 383 265 | 37 165 | |
0,28924 % | Schroder Investment Management North America Inc. | 381 850 | −132 805 | |
0,27956 % | PointState Capital LP | 369 070 | 369 070 | |
0,27955 % | First Light Asset Management, LLC | 369 068 | −287 640 | |
0,27224 % | Holocene Advisors, LP | 359 405 | −350 827 | |
0,26879 % | SEI Investments Management Corporation | 354 856 | −14 086 | |
0,24996 % | C WorldWide Asset Management Fondsmaeglerselskab A/S | 330 000 | −105 000 | |
0,24532 % | Loomis, Sayles & Company, L.P. | 323 865 | −201 913 | |
0,23142 % | BlackRock Financial Management, Inc. | 305 521 | −7 809 | |
0,22930 % | Victory Capital Management Inc. | 302 728 | 212 322 | |
0,22715 % | Weatherbie Capital, LLC | 299 882 | −41 681 | |
0,22660 % | Voloridge Investment Management, LLC | 299 157 | 89 724 | |
0,21974 % | SEB Investment Management AB | 290 104 | −6 627 | |
0,21906 % | Candriam Luxembourg S.A. | 289 197 | −8 101 | |
0,20711 % | Ensign Peak Advisors, Inc. | 273 425 | 0 | |
0,20438 % | BofA Global Research (US) | 269 826 | 173 545 | |
0,20282 % | UBS Financial Services, Inc. | 267 761 | 111 610 | |
0,20074 % | Artemis Investment Management LLP | 265 021 | −5 317 | |
0,20058 % | Dimensional Fund Advisors, L.P. | 264 801 | 69 523 | |
0,19690 % | TwinBeech Capital LP | 259 953 | 148 998 | |
0,19354 % | AXA Investment Managers UK Ltd. | 255 516 | −55 222 | |
0,18554 % | Morgan Stanley Smith Barney LLC | 244 954 | 13 327 | |
0,18378 % | Zweig-DiMenna Associates, Inc. | 242 625 | 165 100 | |
0,17466 % | Tri Locum Partners LP | 230 585 | 40 471 | |
0,17111 % | Schweizerische Nationalbank | 225 900 | 500 | |
0,16936 % | BlackRock Asset Management Ireland Limited | 223 585 | −53 904 | |
0,16637 % | T. Rowe Price Investment Management, Inc. | 219 639 | 363 | |
0,16546 % | AHL Partners LLP | 218 442 | −39 627 | |
0,16399 % | Renaissance Technologies LLC | 216 500 | 16 317 | |