9,81715 % | Beryl Capital Management, LLC | 5 179 529 | 5 179 529 | |
7,99104 % | Eshelman Ventures LLC | 4 216 074 | −300 000 | |
5,59255 % | MedImmune Ventures, Inc. | 2 950 630 | 0 | |
5,35980 % | BlackRock Institutional Trust Company, N.A. | 2 827 830 | 2 167 809 | |
4,72159 % | The Vanguard Group, Inc. | 2 491 109 | 409 536 | |
2,80967 % | Water Island Capital, LLC | 1 482 382 | −5 000 | |
2,58217 % | Woodline Partners LP | 1 362 354 | 1 362 354 | |
2,36008 % | Renaissance Technologies LLC | 1 245 180 | 341 480 | |
2,04633 % | Geode Capital Management, L.L.C. | 1 079 645 | 573 840 | |
1,75930 % | Acadian Asset Management LLC | 928 205 | 494 496 | |
1,56929 % | State Street Global Advisors (US) | 827 956 | 666 850 | |
1,51727 % | Qube Research & Technologies Ltd | 800 511 | 476 045 | |
1,45388 % | D. E. Shaw & Co., L.P. | 767 066 | −18 193 | |
1,09241 % | Connor, Clark & Lunn Investment Management Ltd. | 576 354 | 162 775 | |
1,04246 % | Eshelman (Fredric N) | 550 000 | 300 000 | |
0,98659 % | Two Sigma Investments, LP | 520 525 | 2 694 | |
0,87868 % | Jacobs Levy Equity Management, Inc. | 463 593 | 85 735 | |
0,75444 % | Bridgeway Capital Management, LLC | 398 043 | 206 900 | |
0,72595 % | Morgan Stanley & Co. LLC | 383 009 | 218 005 | |
0,38940 % | Bailey (John E JR) | 205 449 | 97 338 | |
0,37900 % | Eversept Partners, LP | 199 963 | 199 963 | |
0,37786 % | Readystate Asset Management LP | 199 358 | 199 358 | |
0,37028 % | Muir (Glenn P) | 195 358 | 10 000 | |
0,36524 % | State Teachers Retirement System of Ohio | 192 700 | 192 700 | |
0,35160 % | Caption Management, LLC | 185 505 | 87 937 | |
0,34117 % | Needham Investment Management L.L.C. | 180 000 | 0 | |
0,33558 % | PanAgora Asset Management Inc. | 177 051 | 177 051 | |
0,26459 % | Northern Trust Investments, Inc. | 139 600 | 25 717 | |
0,26141 % | Charles Schwab Investment Management, Inc. | 137 921 | 116 405 | |
0,25102 % | BlackRock Investment Management, LLC | 132 437 | 124 360 | |
0,24804 % | Umstead (John W. V) | 130 868 | 34 473 | |
0,24571 % | Fidelity Management & Research Company LLC | 129 638 | 69 698 | |
0,22582 % | BlackRock Financial Management, Inc. | 119 145 | 117 835 | |
0,21986 % | Velleca (Mark A.) | 116 000 | 0 | |
0,21940 % | Goldman Sachs & Company, Inc. | 115 754 | −332 207 | |
0,20548 % | BNY Mellon Asset Management | 108 410 | 108 410 | |
0,20207 % | Perry (Andrew) | 106 614 | 33 663 | |
0,18495 % | ExodusPoint Capital Management, LP | 97 580 | 77 833 | |
0,17981 % | Goldman Sachs Asset Management, L.P. | 94 869 | 94 869 | |
0,16740 % | Numeric Investors LLC | 88 322 | 88 322 | |
0,16611 % | UBS Financial Services, Inc. | 87 637 | 87 329 | |
0,15163 % | Birchview Capital, LP | 80 000 | 0 | |
0,14852 % | BofA Global Research (US) | 78 361 | −300 650 | |
0,14182 % | Dimensional Fund Advisors, L.P. | 74 826 | −2 705 | |
0,14093 % | Virtu Americas LLC | 74 354 | 74 354 | |
0,12685 % | Nuveen LLC | 66 928 | 66 928 | |
0,12304 % | Jane Street Capital, L.L.C. | 64 916 | −268 656 | |
0,12289 % | Malik (Rajesh K.) | 64 837 | −2 475 | |
0,10466 % | Graham Capital Management, L.P. | 55 218 | 35 942 | |
0,09597 % | Rhumbline Advisers Ltd. Partnership | 50 632 | 49 665 | |
0,08857 % | Alpine Global Management, LLC | 46 728 | 46 728 | |
0,07788 % | Hanson (James S) | 41 087 | 15 532 | |
0,07582 % | LUNIS Verm¿gensmanagement AG | 40 000 | −13 000 | |
0,07525 % | Beacon Pointe Advisors LLC | 39 700 | −4 000 | |
0,07468 % | AHL Partners LLP | 39 401 | −235 957 | |
0,07219 % | Avagliano (Mark) | 38 085 | 32 362 | |
0,06690 % | Envestnet Asset Management, Inc. | 35 299 | −122 | |
0,06678 % | BDO Wealth Advisors, LLC | 35 234 | 0 | |
0,06678 % | Choreo, LLC | 35 234 | 0 | |
0,06615 % | Columbia Threadneedle Investments (US) | 34 900 | −600 | |
0,06567 % | Avantis Investors | 34 648 | 18 267 | |
0,06393 % | T. Rowe Price International Ltd | 33 732 | 15 977 | |
0,05445 % | GSA Capital Partners LLP | 28 729 | 17 955 | |
0,05389 % | Florida State Board of Administration | 28 433 | 28 433 | |
0,05312 % | Guggenheim Investments | 28 024 | 27 301 | |
0,05032 % | Corebridge Financial Inc | 26 547 | 26 547 | |
0,05032 % | SunAmerica Asset Management, LLC | 26 547 | 0 | |
0,04907 % | Flowers (Cynthia Louise) | 25 889 | 10 000 | |
0,04704 % | Mellon Investments Corporation | 24 820 | 24 820 | |
0,04623 % | Nicholson (Garry A) | 24 389 | 10 000 | |
0,04365 % | Barclays Bank PLC | 23 032 | 16 730 | |
0,04340 % | Invesco Advisers, Inc. | 22 898 | 22 898 | |
0,04243 % | PDT Partners, LLC | 22 387 | 0 | |
0,04234 % | AllianceBernstein L.P. | 22 340 | 22 340 | |
0,03986 % | JPMorgan Private Bank (United States) | 21 029 | 21 029 | |
0,03984 % | XTX Markets LLC | 21 020 | 10 718 | |
0,03978 % | Los Angeles Capital Management LLC | 20 986 | 20 986 | |
0,03874 % | PGIM Quantitative Solutions LLC | 20 440 | 4 840 | |
0,03832 % | Marathon Trading Investment Management LLC | 20 220 | 20 220 | |
0,03791 % | Secor (Alicia) | 20 000 | 10 000 | |
0,03791 % | Gabelli Funds, LLC | 20 000 | 20 000 | |
0,03365 % | T. Rowe Price Associates, Inc. | 17 755 | 0 | |
0,03237 % | Voya Investment Management LLC | 17 076 | 17 076 | |
0,02994 % | Wells Fargo Bank, N.A. | 15 798 | 15 453 | |
0,02904 % | Adhesion Wealth Advisor Solutions | 15 321 | 15 321 | |
0,02805 % | PenderFund Capital Management, Ltd. | 14 800 | 14 800 | |
0,02428 % | Invesco Capital Management LLC | 12 811 | 12 811 | |
0,02339 % | Mackenzie Investments | 12 338 | 12 338 | |
0,02335 % | Wells Fargo Advisors | 12 320 | −18 400 | |
0,02075 % | Cetera Investment Advisers LLC | 10 948 | −630 | |
0,02035 % | Citi Investment Research (US) | 10 736 | −118 330 | |
0,01914 % | Lee (Jacks) | 10 100 | 10 000 | |
0,01895 % | Sharpless (Norman E. M.D.) | 10 000 | 10 000 | |
0,01836 % | Osaic Holdings, Inc. | 9 686 | −739 | |
0,01788 % | Northern Trust Global Investments | 9 435 | −2 195 | |
0,01762 % | Parametric Portfolio Associates LLC | 9 297 | 9 297 | |
0,01739 % | Morgan Stanley Smith Barney LLC | 9 175 | 400 | |
0,01669 % | Manulife Investment Management (North America) Limited | 8 808 | 0 | |
0,01328 % | BlackRock Fund Advisors | 7 005 | 7 005 | |
0,01273 % | Tower Research Capital LLC | 6 714 | 2 610 | |