14,12864 % | Dexcel Pharma Technologies, Ltd. | 102 849 443 | 0 | |
9,77022 % | SB Investment Advisers (UK) Limited | 71 122 349 | −239 039 | |
9,52936 % | Viking Global Investors LP | 69 368 961 | 213 115 | |
9,16543 % | QVT Financial LP | 66 719 779 | 0 | |
7,33999 % | Ramaswamy (Vivek) | 53 431 426 | 4 502 000 | |
6,39483 % | Fidelity Management & Research Company LLC | 46 551 146 | 11 210 583 | |
4,27861 % | BlackRock Institutional Trust Company, N.A. | 31 146 160 | −956 728 | |
3,65930 % | Morgan Stanley Investment Management Inc. (US) | 26 637 886 | −2 046 917 | |
3,31702 % | Sukhatme (Mayukh) | 24 146 230 | 18 836 547 | |
3,15956 % | Rubric Capital Management LP | 23 000 000 | 3 000 000 | |
2,53351 % | State Street Global Advisors (US) | 18 442 688 | 1 289 554 | |
2,36045 % | Gline (Matthew) | 17 182 931 | −10 945 | |
1,67985 % | Patient Square Capital, LP | 12 228 465 | 0 | |
1,41751 % | Two Seas Capital LP | 10 318 764 | 2 388 415 | |
1,11503 % | The Vanguard Group, Inc. | 8 116 856 | 68 375 | |
1,09911 % | Woodline Partners LP | 8 000 939 | −3 171 367 | |
1,04387 % | Venker (Eric) | 7 598 834 | −10 945 | |
0,86337 % | Geode Capital Management, L.L.C. | 6 284 899 | 238 053 | |
0,75698 % | Invesco Capital Management LLC | 5 510 420 | 5 384 520 | |
0,66387 % | Anchorage Capital Group, L.L.C. | 4 832 642 | 0 | |
0,66089 % | Greenlight Capital, Inc. | 4 810 960 | 620 470 | |
0,64757 % | Gold (Daniel Allen) | 4 714 005 | −2 543 456 | |
0,61607 % | PointState Capital LP | 4 484 698 | 438 213 | |
0,58256 % | Norges Bank Investment Management (NBIM) | 4 240 777 | 544 810 | |
0,57010 % | Adar1 Capital Management LLC | 4 150 009 | 1 358 139 | |
0,54053 % | Adage Capital Management, L.P. | 3 934 752 | 0 | |
0,47443 % | Loomis, Sayles & Company, L.P. | 3 453 604 | 260 262 | |
0,43453 % | Goldman Sachs Asset Management, L.P. | 3 163 175 | 1 900 518 | |
0,43216 % | Nuveen LLC | 3 145 906 | 818 063 | |
0,42585 % | BlackBarn Capital Partners LP | 3 100 000 | 1 199 406 | |
0,41310 % | First Trust Advisors L.P. | 3 007 142 | 1 290 584 | |
0,40525 % | Troluce Capital Advisors LLC | 2 950 000 | 2 950 000 | |
0,38447 % | Baker Bros. Advisors LP | 2 798 716 | −4 615 118 | |
0,37673 % | BVF Partners L.P. | 2 742 409 | 0 | |
0,37265 % | StemPoint Capital LP | 2 712 741 | −841 103 | |
0,36439 % | Pertento Partners LLP | 2 652 562 | 824 499 | |
0,34450 % | Jane Street Capital, L.L.C. | 2 507 783 | 1 806 506 | |
0,33164 % | BlackRock Financial Management, Inc. | 2 414 186 | 44 413 | |
0,32846 % | Whitefort Capital Management, LP | 2 391 000 | 0 | |
0,30704 % | Morgan Stanley & Co. LLC | 2 235 070 | −2 842 272 | |
0,30001 % | Tejara Capital Ltd. | 2 183 943 | −416 352 | |
0,29134 % | Charles Schwab Investment Management, Inc. | 2 120 785 | 8 374 | |
0,27668 % | BofA Global Research (US) | 2 014 112 | 322 658 | |
0,27474 % | Impax Asset Management LLC | 2 000 000 | 400 000 | |
0,27474 % | Prosight Capital | 2 000 000 | 140 000 | |
0,26505 % | Northern Trust Investments, Inc. | 1 929 399 | 460 351 | |
0,26431 % | Citadel Advisors LLC | 1 924 037 | −1 215 542 | |
0,25667 % | Sofinnova Investments, Inc | 1 868 412 | 866 708 | |
0,25559 % | ClearBridge Investments, LLC | 1 860 536 | 630 712 | |
0,24402 % | Pictet Asset Management (Japan) Ltd. | 1 776 346 | 794 531 | |
0,23969 % | Lakewood Capital Management, LP | 1 744 800 | 0 | |
0,23962 % | Tyro Capital Management LLC | 1 744 327 | 248 733 | |
0,23557 % | Atalaya Capital Management LP | 1 714 843 | 1 677 367 | |
0,22422 % | Penn Davis McFarland, Inc. | 1 632 194 | 275 | |
0,20606 % | Polar Capital LLP | 1 500 000 | 0 | |
0,19978 % | RTW Investments L.P. | 1 454 273 | 0 | |
0,19564 % | Mellon Investments Corporation | 1 424 154 | 3 901 | |
0,17962 % | J. Goldman & Co., L.P. | 1 307 543 | 1 307 543 | |
0,17386 % | Melqart Asset Management (UK) Limited | 1 265 609 | 1 265 609 | |
0,17300 % | Manchester (Keith S) | 1 259 353 | −486 594 | |
0,16786 % | Pictet Asset Management Ltd. | 1 221 929 | −2 486 157 | |
0,16556 % | LMR Partners LLP | 1 205 168 | 754 162 | |
0,16092 % | BNY Mellon Asset Management | 1 171 428 | 31 614 | |
0,15872 % | Principal Global Investors (Equity) | 1 155 372 | −119 365 | |
0,14187 % | TIFF Advisory Services, Inc. | 1 032 752 | −115 000 | |
0,14098 % | Franklin Advisers, Inc. | 1 026 284 | −151 | |
0,14088 % | Goldman Sachs & Company, Inc. | 1 025 527 | 829 670 | |
0,13737 % | Ghost Tree Capital, LLC | 1 000 000 | −300 000 | |
0,13737 % | Alyeska Investment Group, L.P. | 1 000 000 | 1 000 000 | |
0,12639 % | UBS Asset Management (Switzerland) | 920 038 | 162 551 | |
0,12178 % | Rhumbline Advisers Ltd. Partnership | 886 493 | −70 856 | |
0,12057 % | Rafferty Asset Management LLC | 877 709 | −34 484 | |
0,09819 % | Marshall Wace LLP | 714 760 | 660 660 | |
0,09810 % | Schweizerische Nationalbank | 714 146 | 158 600 | |
0,09307 % | Morgan Stanley Investment Management Ltd. (UK) | 677 487 | 0 | |
0,09245 % | Farallon Capital Management, L.L.C. | 673 000 | −225 600 | |
0,08890 % | Point72 Asset Management, L.P. | 647 126 | 185 226 | |
0,08857 % | BlackRock Asset Management Ireland Limited | 644 775 | 29 386 | |
0,08526 % | Managed Account Advisors LLC | 620 645 | 62 801 | |
0,07827 % | Platinum Asset Management | 569 745 | −99 302 | |
0,07818 % | Legal & General Investment Management Ltd. | 569 144 | 134 804 | |
0,07490 % | BlackRock Investment Management, LLC | 545 266 | −113 976 | |
0,06791 % | UBS Financial Services, Inc. | 494 349 | −43 248 | |
0,06737 % | Pearl River Capital, LLC | 490 436 | 490 436 | |
0,06656 % | Privium Fund Management BV | 484 500 | −83 295 | |
0,06183 % | SunAmerica Asset Management, LLC | 450 065 | 444 212 | |
0,06158 % | BlackRock Investment Management (UK) Ltd. | 448 288 | 149 972 | |
0,06157 % | AllianceBernstein L.P. | 448 233 | −20 047 | |
0,06006 % | Parametric Portfolio Associates LLC | 437 218 | 218 134 | |
0,05882 % | Corebridge Financial Inc | 428 194 | 428 194 | |
0,05843 % | Northern Trust Global Investments | 425 348 | 264 905 | |
0,05840 % | Pier Capital, LLC | 425 087 | 96 905 | |
0,05739 % | The Retirement Systems of Alabama | 417 736 | −5 750 | |
0,05632 % | 683 Capital Management LLC | 410 000 | 139 866 | |
0,05628 % | Voloridge Investment Management, LLC | 409 656 | −190 142 | |
0,05503 % | State Street Global Advisors Ireland Limited | 400 562 | 103 491 | |
0,05495 % | Integral Health Asset Management, LLC | 400 000 | −200 000 | |
0,05495 % | Atika Capital Management LLC | 400 000 | −134 980 | |
0,05463 % | Invesco Advisers, Inc. | 397 645 | 19 976 | |
0,05373 % | JP Morgan Asset Management | 391 138 | 41 501 | |