18,39197 % | VenBio Partners LLC | 9 699 925 | 0 | |
14,72988 % | Fidelity Management & Research Company LLC | 7 768 541 | 262 468 | |
8,00161 % | Vivo Capital, LLC | 4 220 048 | 0 | |
7,66174 % | Tang Capital Management, LLC | 4 040 800 | 4 040 800 | |
7,65349 % | Redmile Group, LLC | 4 036 451 | −290 058 | |
6,82594 % | Vestal Point Capital, LP | 3 600 000 | 990 000 | |
5,59268 % | Lightstone Ventures, L.P. | 2 949 580 | −1 259 395 | |
4,47604 % | BlackRock Institutional Trust Company, N.A. | 2 360 662 | 425 886 | |
4,13512 % | MPM BioImpact LLC | 2 180 864 | 912 393 | |
3,79669 % | Millennium Management LLC | 2 002 374 | −959 297 | |
3,59208 % | OrbiMed Advisors, LLC | 1 894 462 | −823 508 | |
3,26325 % | The Vanguard Group, Inc. | 1 721 039 | 160 784 | |
2,98750 % | Paradigm BioCapital Advisors LP | 1 575 605 | 1 575 605 | |
1,33778 % | State Street Global Advisors (US) | 705 547 | 151 680 | |
1,32804 % | Geode Capital Management, L.L.C. | 700 406 | 95 692 | |
1,20531 % | Marshall Wace LLP | 635 679 | 514 133 | |
0,92106 % | Morgan Stanley & Co. LLC | 485 765 | 344 280 | |
0,83087 % | Renaissance Technologies LLC | 438 200 | 204 100 | |
0,82932 % | Pons (Jaume) | 437 385 | −1 937 | |
0,75268 % | Privium Fund Management BV | 396 966 | 396 966 | |
0,68226 % | Two Sigma Investments, LP | 359 826 | 284 371 | |
0,58310 % | Kennedy Capital Management LLC | 307 529 | 300 573 | |
0,57660 % | Point72 Asset Management, L.P. | 304 100 | 304 100 | |
0,46044 % | Randolph (Sophia) | 242 836 | −1 365 | |
0,44752 % | Charles Schwab Investment Management, Inc. | 236 020 | 26 261 | |
0,43994 % | Jacobs Levy Equity Management, Inc. | 232 022 | 232 022 | |
0,41814 % | Northern Trust Investments, Inc. | 220 525 | 1 600 | |
0,37816 % | Cubist Systematic Strategies, LLC | 199 441 | 199 441 | |
0,34524 % | Parametric Portfolio Associates LLC | 182 082 | −14 302 | |
0,33617 % | BlackRock Financial Management, Inc. | 177 298 | 36 315 | |
0,31735 % | Goodman (Corey S) | 167 370 | 0 | |
0,27629 % | Wellington Management Company, LLP | 145 717 | 18 680 | |
0,26545 % | Jump Financial, LLC | 140 000 | 115 194 | |
0,26008 % | Goldman Sachs & Company, Inc. | 137 164 | 24 916 | |
0,20812 % | Walleye Capital LLC | 109 762 | 71 521 | |
0,20749 % | Lettmann (Jason) | 109 429 | −2 191 | |
0,19718 % | Nuveen LLC | 103 995 | 0 | |
0,17233 % | BlackRock Investment Management, LLC | 90 887 | 14 205 | |
0,14808 % | Jane Street Capital, L.L.C. | 78 100 | 18 905 | |
0,14806 % | Goldman Sachs Asset Management, L.P. | 78 088 | 33 334 | |
0,14536 % | BNY Mellon Asset Management | 76 664 | 20 058 | |
0,14243 % | State of Wisconsin Investment Board | 75 120 | 20 754 | |
0,13930 % | Susquehanna Portfolio Strategies, LLC | 73 468 | −17 489 | |
0,13601 % | AllianceBernstein L.P. | 71 730 | 32 940 | |
0,12990 % | Citadel Advisors LLC | 68 511 | −1 166 704 | |
0,12554 % | abrdn Inc. | 66 211 | 0 | |
0,10470 % | Rhumbline Advisers Ltd. Partnership | 55 220 | 5 360 | |
0,09367 % | Schweizerische Nationalbank | 49 400 | 5 200 | |
0,09229 % | Garcia (Peter S) | 48 673 | −761 | |
0,08808 % | Fidelity Institutional Asset Management | 46 455 | 29 716 | |
0,08371 % | Balyasny Asset Management LP | 44 149 | 44 149 | |
0,07954 % | Nan Fung Life Sciences | 41 950 | 0 | |
0,07815 % | Algert Global LLC | 41 215 | 41 215 | |
0,07776 % | BofA Global Research (US) | 41 010 | −6 145 | |
0,07774 % | Deka Verm¿gensmanagement GmbH | 41 000 | 0 | |
0,07774 % | Deka Investment GmbH | 41 000 | 16 700 | |
0,07182 % | LSV Asset Management | 37 880 | 10 850 | |
0,06834 % | Pinto (Shelly) | 36 045 | −564 | |
0,06746 % | BlackRock Asset Management Ireland Limited | 35 580 | 4 043 | |
0,06550 % | Dimensional Fund Advisors, L.P. | 34 543 | −15 798 | |
0,06483 % | SEI Investments Management Corporation | 34 190 | 14 190 | |
0,06176 % | Verition Fund Management LLC | 32 571 | 32 571 | |
0,06013 % | Wealth Enhancement Advisory Services, LLC | 31 710 | 291 | |
0,05957 % | The Financial Advisory Group, Inc | 31 417 | 0 | |
0,05841 % | BlackRock Advisors (UK) Limited | 30 804 | 679 | |
0,05496 % | Avantis Investors | 28 985 | 8 467 | |
0,05485 % | Legal & General Investment Management Ltd. | 28 926 | 11 740 | |
0,05339 % | Mellon Investments Corporation | 28 157 | 5 141 | |
0,05194 % | SG Americas Securities, L.L.C. | 27 394 | 6 888 | |
0,05122 % | Connor, Clark & Lunn Investment Management Ltd. | 27 014 | −2 070 | |
0,04788 % | California State Teachers Retirement System | 25 254 | 2 457 | |
0,04740 % | LMR Partners LLP | 25 000 | 25 000 | |
0,04657 % | Susquehanna International Group, LLP | 24 561 | 859 | |
0,04540 % | Graham Capital Management, L.P. | 23 942 | 23 942 | |
0,04491 % | American Century Investment Management, Inc. | 23 685 | −5 978 | |
0,04412 % | Northern Trust Global Investments | 23 270 | −2 261 | |
0,04204 % | Sherbrooke Park Advisors LLC | 22 172 | 22 172 | |
0,03944 % | Dimensional Fund Advisors, Ltd. | 20 801 | 0 | |
0,03940 % | Quest Partners, LLC | 20 781 | −4 251 | |
0,03839 % | Assenagon Asset Management S.A. | 20 245 | 91 | |
0,03812 % | J.P. Morgan Securities LLC | 20 102 | 102 | |
0,03591 % | D. E. Shaw & Co., L.P. | 18 940 | 18 940 | |
0,03553 % | Aperio Group, LLC | 18 736 | −14 391 | |
0,03428 % | AQR Capital Management, LLC | 18 079 | 6 080 | |
0,03370 % | Corebridge Financial Inc | 17 771 | 17 771 | |
0,03283 % | Barclays Bank PLC | 17 317 | −11 318 | |
0,03249 % | UBS Fund Management (Switzerland) AG | 17 137 | 1 372 | |
0,03110 % | Occudo Quantitative Strategies LP | 16 402 | 16 402 | |
0,03060 % | MetLife Investment Management, LLC | 16 140 | 1 579 | |
0,03034 % | Abaris Investment Management AG | 16 000 | 8 000 | |
0,03003 % | Commonwealth Financial Network | 15 840 | 15 840 | |
0,02930 % | UBS Financial Services, Inc. | 15 453 | −13 621 | |
0,02763 % | Mirae Asset Global Investments (USA) LLC | 14 571 | 3 634 | |
0,02669 % | JPMorgan Private Bank (United States) | 14 077 | 3 509 | |
0,02590 % | Manulife Investment Management (North America) Limited | 13 662 | −46 457 | |
0,02465 % | SunAmerica Asset Management, LLC | 13 000 | −398 | |
0,02389 % | Engineers Gate Manager, L.P. | 12 600 | 12 600 | |
0,02374 % | New York State Common Retirement Fund | 12 522 | 0 | |
0,02157 % | Vaughan Nelson Investment Management, L.P. | 11 377 | 0 | |
0,02126 % | Voya Investment Management LLC | 11 215 | 11 215 | |