11,54700 % | Fidelity Management & Research Company LLC | 14 392 175 | −238 466 | 30.6.2024 |
7,84422 % | The Vanguard Group, Inc. | 9 777 040 | 58 630 | 30.6.2024 |
7,11562 % | Janus Henderson Investors | 8 868 907 | 1 195 039 | 30.6.2024 |
6,58196 % | RA Capital Management, LP | 8 203 754 | 0 | 30.6.2024 |
6,32651 % | BlackRock Institutional Trust Company, N.A. | 7 885 361 | 314 385 | 30.6.2024 |
3,68507 % | Wellington Management Company, LLP | 4 593 066 | −326 304 | 30.6.2024 |
3,31639 % | Capital Research Global Investors | 4 133 544 | −6977 | 30.6.2024 |
3,22737 % | T. Rowe Price Investment Management, Inc. | 4 022 589 | 469 622 | 30.6.2024 |
2,70150 % | State Street Global Advisors (US) | 3 367 147 | 30 055 | 30.6.2024 |
2,47001 % | T. Rowe Price Associates, Inc. | 3 078 615 | −8212 | 30.6.2024 |
1,95906 % | Geode Capital Management, L.L.C. | 2 441 772 | 154 397 | 30.6.2024 |
1,74519 % | Franklin Advisers, Inc. | 2 175 205 | 278 124 | 30.6.2024 |
1,66957 % | Darwin Global Management Ltd | 2 080 946 | −669 858 | 30.6.2024 |
1,55227 % | Driehaus Capital Management, LLC | 1 934 747 | 66 940 | 30.6.2024 |
1,54794 % | Westfield Capital Management Company, L.P. | 1 929 348 | 343 253 | 30.6.2024 |
1,49439 % | Perceptive Advisors LLC | 1 862 608 | −70 151 | 30.6.2024 |
1,42423 % | Fidelity Institutional Asset Management | 1 775 165 | 144 647 | 30.6.2024 |
1,39187 % | AllianceBernstein L.P. | 1 734 821 | −45 882 | 30.6.2024 |
1,10970 % | Jennison Associates LLC | 1 383 131 | 126 248 | 30.6.2024 |
1,05138 % | Fred Alger Management, LLC | 1 310 436 | −86 275 | 30.6.2024 |
1,04702 % | Commodore Capital LP | 1 305 000 | 445 000 | 30.6.2024 |
0,98253 % | BlackRock Financial Management, Inc. | 1 224 621 | 45 069 | 30.6.2024 |
0,88254 % | Cormorant Asset Management, LP | 1 100 000 | 415 000 | 30.6.2024 |
0,83393 % | Frazier Life Sciences Management, L.P. | 1 039 405 | −100 000 | 30.6.2024 |
0,81758 % | Invesco Advisers, Inc. | 1 019 035 | −1858 | 30.6.2024 |
0,80499 % | JP Morgan Asset Management | 1 003 336 | 37 836 | 30.6.2024 |
0,78985 % | Norges Bank Investment Management (NBIM) | 984 464 | 68 952 | 30.6.2024 |
0,72384 % | Fidelity Investments Canada ULC | 902 197 | 7267 | 30.6.2024 |
0,70301 % | Charles Schwab Investment Management, Inc. | 876 237 | 42 619 | 30.6.2024 |
0,67245 % | Northern Trust Investments, Inc. | 838 142 | −28 926 | 30.6.2024 |
0,64851 % | Braidwell LP | 808 303 | −404 400 | 30.6.2024 |
0,63856 % | OrbiMed Advisors, LLC | 795 900 | −270 231 | 30.6.2024 |
0,63626 % | Pivotal Bioventure Partners Investment Advisor LLC | 793 036 | 0 | 30.6.2024 |
0,60433 % | Kynam Capital Management LP | 753 240 | 8240 | 30.6.2024 |
0,60173 % | Novo Holdings A/S | 750 000 | −200 000 | 30.9.2024 |
0,59303 % | Eventide Asset Management, LLC | 739 153 | 81 947 | 30.6.2024 |
0,56716 % | Woodline Partners LP | 706 903 | 313 199 | 30.6.2024 |
0,55192 % | Maverick Capital, Ltd. | 687 908 | 332 777 | 30.6.2024 |
0,50321 % | Paradigm BioCapital Advisors LP | 627 202 | −612 793 | 30.6.2024 |
0,46133 % | Avoro Capital Advisors LLC | 575 000 | 0 | 30.6.2024 |
0,42755 % | Pictet Asset Management Ltd. | 532 904 | −328 665 | 30.6.2024 |
0,42329 % | American Century Investment Management, Inc. | 527 594 | 65 870 | 30.6.2024 |
0,37121 % | Ensign Peak Advisors, Inc. | 462 682 | −13 018 | 30.6.2024 |
0,35487 % | Amundi Asset Management US, Inc. | 442 308 | 139 951 | 30.6.2024 |
0,34321 % | Pickering (Grant E) | 427 779 | −15 000 | 8.10.2024 |
0,34150 % | Federated Hermes Global Investment Management Corp. | 425 640 | −110 | 30.6.2024 |
0,33594 % | Balyasny Asset Management LP | 418 715 | 418 715 | 30.6.2024 |
0,30929 % | BofA Global Research (US) | 385 494 | 175 420 | 30.6.2024 |
0,30538 % | Goldman Sachs & Company, Inc. | 380 629 | −31 175 | 30.6.2024 |
0,29462 % | Brown Advisory | 367 217 | 316 734 | 30.6.2024 |
0,27900 % | Goldman Sachs Asset Management, L.P. | 347 747 | 61 059 | 30.6.2024 |
0,27878 % | Allspring Global Investments, LLC | 347 474 | 3922 | 30.9.2024 |
0,25459 % | Nuveen LLC | 317 323 | 10 052 | 30.6.2024 |
0,25066 % | TD Asset Management Inc. | 312 426 | 31 138 | 30.6.2024 |
0,24672 % | Victory Capital Management Inc. | 307 516 | 26 641 | 30.6.2024 |
0,24256 % | BlackRock Investment Management, LLC | 302 327 | 23 446 | 30.6.2024 |
0,24069 % | EcoR1 Capital, LLC | 300 000 | 0 | 30.6.2024 |
0,24069 % | Tang Capital Management, LLC | 300 000 | 0 | 30.6.2024 |
0,23267 % | Farallon Capital Management, L.L.C. | 290 000 | −87 400 | 30.6.2024 |
0,22917 % | Putnam Investment Management, L.L.C. | 285 640 | 41 171 | 30.6.2024 |
0,22786 % | Avidity Partners Management LP | 284 000 | 0 | 30.6.2024 |
0,22722 % | BlackRock Investment Management (UK) Ltd. | 283 204 | 26 464 | 30.6.2024 |
0,22653 % | Eagle Asset Management, Inc. | 282 351 | −56 449 | 30.6.2024 |
0,22416 % | Voya Investment Management LLC | 279 398 | 96 267 | 30.6.2024 |
0,21952 % | Cercano Management LLC | 273 608 | 1457 | 30.6.2024 |
0,21905 % | Comerica, Inc. | 273 025 | 84 941 | 30.6.2024 |
0,21495 % | BNY Mellon Asset Management | 267 915 | 20 855 | 30.6.2024 |
0,20895 % | Columbia Threadneedle Investments (US) | 260 431 | 162 012 | 30.6.2024 |
0,20883 % | First Turn Management, LLC | 260 281 | 0 | 30.6.2024 |
0,19756 % | Lord, Abbett & Co. LLC | 246 242 | −138 121 | 30.6.2024 |
0,18470 % | D. E. Shaw & Co., L.P. | 230 207 | −137 042 | 30.6.2024 |
0,17755 % | Morgan Stanley & Co. LLC | 221 296 | −72 415 | 30.6.2024 |
0,17304 % | Saturn V Capital Management LP | 215 680 | 30 505 | 30.6.2024 |
0,16346 % | Millennium Management LLC | 203 731 | −3251 | 30.6.2024 |
0,14934 % | ClearBridge Investments, LLC | 186 141 | 186 141 | 30.6.2024 |
0,14863 % | Soleus Capital Management, L.P. | 185 250 | −22 500 | 30.6.2024 |
0,14762 % | BlackRock Advisors (UK) Limited | 183 988 | 3293 | 30.9.2024 |
0,14567 % | Parametric Portfolio Associates LLC | 181 563 | −7614 | 30.6.2024 |
0,14546 % | Schweizerische Nationalbank | 181 300 | 3300 | 30.6.2024 |
0,14135 % | Mellon Investments Corporation | 176 182 | 30 003 | 30.6.2024 |
0,13302 % | Citi Investment Research (US) | 165 795 | 20 928 | 30.6.2024 |
0,13226 % | SEI Investments Management Corporation | 164 843 | 67 939 | 30.6.2024 |
0,13032 % | Segall Bryant & Hamill, LLC | 162 432 | 4411 | 30.6.2024 |
0,12780 % | Rhumbline Advisers Ltd. Partnership | 159 295 | 11 001 | 30.6.2024 |
0,12758 % | Macquarie Investment Management | 159 012 | 39 039 | 30.6.2024 |
0,12695 % | BlackRock Asset Management Ireland Limited | 158 235 | 1236 | 30.6.2024 |
0,12258 % | California Public Employees' Retirement System | 152 778 | −4208 | 30.6.2024 |
0,12050 % | Parkman Healthcare Partners LLC | 150 191 | 235 | 30.6.2024 |
0,12035 % | Ghost Tree Capital, LLC | 150 000 | 55 000 | 30.6.2024 |
0,11211 % | First Light Asset Management, LLC | 139 729 | 79 445 | 30.6.2024 |
0,10570 % | Manulife Investment Management (North America) Limited | 131 749 | 12 667 | 30.6.2024 |
0,10266 % | Barclays Bank PLC | 127 952 | −1300 | 30.6.2024 |
0,09224 % | Pier Capital, LLC | 114 969 | −12 415 | 30.6.2024 |
0,09094 % | Tri Locum Partners LP | 113 344 | 113 344 | 30.6.2024 |
0,08858 % | Acuta Capital Partners, LLC | 110 400 | 5570 | 30.6.2024 |
0,08672 % | Neuberger Berman, LLC | 108 092 | 5781 | 30.6.2024 |
0,08554 % | Jane Street Capital, L.L.C. | 106 611 | 90 929 | 30.6.2024 |
0,08502 % | JPMorgan Asset Management U.K. Limited | 105 974 | 1052 | 30.6.2024 |
0,08423 % | Legal & General Investment Management Ltd. | 104 984 | 10 201 | 30.6.2024 |
0,08336 % | MFS Investment Management | 103 906 | 2967 | 31.8.2024 |