8,59336 % | The Vanguard Group, Inc. | 14 354 342 | -381 474 | 30. 6. 2024 |
8,17780 % | Wellington Management Company, LLP | 13 660 196 | -1 054 530 | 30. 6. 2024 |
6,52702 % | BlackRock Institutional Trust Company, N.A. | 10 902 738 | 779 058 | 30. 6. 2024 |
5,84153 % | Farallon Capital Management, L.L.C. | 9 757 692 | 2 249 820 | 30. 6. 2024 |
4,53130 % | Baker Bros. Advisors LP | 7 569 090 | 19 841 | 30. 6. 2024 |
3,76960 % | Nextech Invest, Ltd. | 6 296 740 | 0 | 30. 6. 2024 |
3,58071 % | BVF Partners L.P. | 5 981 212 | 0 | 30. 6. 2024 |
3,36748 % | Fidelity Management & Research Company LLC | 5 625 035 | 1 458 597 | 30. 6. 2024 |
3,17713 % | Alphabet, Inc. | 5 307 075 | 5 563 | 30. 6. 2024 |
3,14840 % | Paradigm BioCapital Advisors LP | 5 259 089 | 2 344 114 | 30. 6. 2024 |
3,03584 % | State Street Global Advisors (US) | 5 071 068 | -314 952 | 30. 6. 2024 |
3,03077 % | T. Rowe Price Associates, Inc. | 5 062 599 | 391 615 | 30. 6. 2024 |
3,01072 % | Bellevue Asset Management AG | 5 029 100 | -44 500 | 30. 6. 2024 |
2,77791 % | Janus Henderson Investors | 4 640 218 | 728 099 | 30. 6. 2024 |
2,63822 % | Casdin Capital, LLC | 4 406 875 | -1 210 724 | 30. 6. 2024 |
2,56194 % | Boxer Capital, L.L.C. | 4 279 464 | 0 | 30. 6. 2024 |
1,99692 % | Geode Capital Management, L.L.C. | 3 335 656 | 282 965 | 30. 6. 2024 |
1,97006 % | Woodline Partners LP | 3 290 791 | -506 357 | 30. 6. 2024 |
1,84990 % | Deerfield Management Company, L.P. | 3 090 073 | 0 | 30. 6. 2024 |
1,64543 % | Andreessen Horowitz | 2 748 523 | 0 | 30. 6. 2024 |
1,41498 % | Balyasny Asset Management LP | 2 363 584 | 708 689 | 30. 6. 2024 |
1,39520 % | Borisy (Alexis) | 2 330 542 | 4 248 | 20. 6. 2024 |
1,33159 % | JP Morgan Asset Management | 2 224 283 | -182 612 | 30. 6. 2024 |
1,31913 % | Holocene Advisors, LP | 2 203 474 | -218 937 | 30. 6. 2024 |
1,10671 % | Norges Bank Investment Management (NBIM) | 1 848 647 | 1 566 942 | 30. 6. 2024 |
0,99648 % | Lord, Abbett & Co. LLC | 1 664 516 | -13 315 | 31. 8. 2024 |
0,71839 % | Logos Global Management LLC | 1 200 000 | 1 200 000 | 30. 6. 2024 |
0,68419 % | BlackRock Financial Management, Inc. | 1 142 863 | 79 755 | 30. 6. 2024 |
0,66432 % | Charles Schwab Investment Management, Inc. | 1 109 684 | 57 421 | 30. 6. 2024 |
0,64180 % | Northern Trust Investments, Inc. | 1 072 055 | -37 405 | 30. 6. 2024 |
0,61960 % | Goldman Sachs & Company, Inc. | 1 034 972 | 334 291 | 30. 6. 2024 |
0,60810 % | Invus Public Equities Advisors, LLC | 1 015 776 | -302 873 | 30. 6. 2024 |
0,59714 % | Frazier Life Sciences Management, L.P. | 997 455 | 0 | 30. 6. 2024 |
0,56465 % | Rock Springs Capital Management LP | 943 195 | 19 514 | 30. 6. 2024 |
0,54718 % | Hood River Capital Management LLC | 914 003 | 914 003 | 30. 6. 2024 |
0,51256 % | Soleus Capital Management, L.P. | 856 178 | 127 478 | 30. 6. 2024 |
0,50856 % | Morgan Stanley & Co. LLC | 849 505 | 6 716 | 30. 6. 2024 |
0,48854 % | Marshall Wace LLP | 816 055 | -719 885 | 30. 6. 2024 |
0,45199 % | Avidity Partners Management LP | 755 000 | 120 000 | 30. 6. 2024 |
0,43670 % | Finepoint Capital LP | 729 464 | 52 364 | 30. 6. 2024 |
0,39665 % | Candriam Luxembourg S.A. | 662 564 | 0 | 30. 9. 2024 |
0,38962 % | Eventide Asset Management, LLC | 650 826 | 289 826 | 30. 6. 2024 |
0,38034 % | Columbia Threadneedle Investments (UK) | 635 319 | -245 391 | 30. 6. 2024 |
0,37222 % | JPMorgan Asset Management U.K. Limited | 621 752 | -218 680 | 30. 6. 2024 |
0,35657 % | Goldsmith Mark A | 595 609 | 0 | 11. 10. 2024 |
0,33186 % | Candriam Belgium S.A. | 554 334 | -29 616 | 30. 6. 2024 |
0,32483 % | Victory Capital Management Inc. | 542 601 | -57 980 | 30. 6. 2024 |
0,32339 % | Pzena Investment Management, LLC | 540 194 | -160 971 | 30. 6. 2024 |
0,31089 % | American Century Investment Management, Inc. | 519 305 | 519 305 | 30. 6. 2024 |
0,30645 % | Dafna Capital Management, LLC | 511 894 | 0 | 30. 6. 2024 |
0,30446 % | MIC Capital Management UK LLP | 508 569 | 0 | 30. 6. 2024 |
0,29746 % | Columbia Threadneedle Investments (US) | 496 878 | 49 167 | 30. 6. 2024 |
0,28908 % | BlackRock Advisors (UK) Limited | 482 883 | 617 | 30. 9. 2024 |
0,27245 % | Sofinnova Investments, Inc | 455 099 | 455 099 | 30. 6. 2024 |
0,27052 % | BlackRock Asset Management Ireland Limited | 451 870 | 115 991 | 30. 6. 2024 |
0,25154 % | BlackRock Investment Management, LLC | 420 169 | 59 350 | 30. 6. 2024 |
0,24532 % | Nuveen LLC | 409 781 | 45 858 | 30. 6. 2024 |
0,24476 % | Citadel Advisors LLC | 408 842 | -179 246 | 30. 6. 2024 |
0,23916 % | Goldman Sachs Asset Management, L.P. | 399 489 | -13 221 | 30. 6. 2024 |
0,23434 % | BlackRock Investment Management (UK) Ltd. | 391 439 | 44 624 | 30. 6. 2024 |
0,23383 % | Dimensional Fund Advisors, L.P. | 390 583 | -940 676 | 30. 6. 2024 |
0,22811 % | BofA Global Research (US) | 381 041 | -140 355 | 30. 6. 2024 |
0,22785 % | Jane Street Capital, L.L.C. | 380 594 | 251 127 | 30. 6. 2024 |
0,21696 % | BNY Mellon Asset Management | 362 416 | 46 589 | 30. 6. 2024 |
0,20246 % | Partners HealthCare System, Inc | 338 191 | 0 | 30. 9. 2024 |
0,19727 % | First Turn Management, LLC | 329 519 | 329 519 | 30. 6. 2024 |
0,19456 % | Integral Health Asset Management, LLC | 325 000 | -95 000 | 30. 6. 2024 |
0,19134 % | AllianceBernstein L.P. | 319 618 | -3 746 | 30. 6. 2024 |
0,18402 % | Columbia Wanger Asset Management, LLC | 307 387 | 0 | 30. 6. 2024 |
0,17325 % | MPM BioImpact LLC | 289 396 | 16 179 | 30. 6. 2024 |
0,16927 % | AHL Partners LLP | 282 746 | 253 449 | 30. 6. 2024 |
0,16643 % | Mubadala Investment Company PJSC | 278 000 | 0 | 30. 6. 2024 |
0,16134 % | Ensign Peak Advisors, Inc. | 269 504 | 229 721 | 30. 6. 2024 |
0,16102 % | Mellon Investments Corporation | 268 962 | 65 210 | 30. 6. 2024 |
0,15749 % | Voya Investment Management LLC | 263 079 | -20 554 | 30. 6. 2024 |
0,14978 % | TD Asset Management Inc. | 250 194 | -4 400 | 30. 6. 2024 |
0,14918 % | Qube Research & Technologies Ltd | 249 188 | 81 708 | 30. 6. 2024 |
0,14574 % | Bessemer Trust Company, N.A. (US) | 243 442 | 0 | 30. 6. 2024 |
0,13683 % | Rhumbline Advisers Ltd. Partnership | 228 567 | 19 257 | 30. 6. 2024 |
0,13680 % | Susquehanna Fundamental Investments, LLC | 228 513 | 22 000 | 30. 6. 2024 |
0,13645 % | Point72 Asset Management, L.P. | 227 922 | 227 922 | 30. 6. 2024 |
0,13611 % | HSBC Private Bank (Suisse) S.A. | 227 365 | 19 081 | 31. 8. 2024 |
0,13579 % | Schweizerische Nationalbank | 226 831 | 26 700 | 30. 6. 2024 |
0,13419 % | Walleye Capital LLC | 224 143 | 189 186 | 30. 6. 2024 |
0,13188 % | TwinBeech Capital LP | 220 289 | 220 289 | 30. 6. 2024 |
0,13037 % | UBS Financial Services, Inc. | 217 763 | -87 216 | 30. 6. 2024 |
0,12714 % | Manulife Investment Management (North America) Limited | 212 368 | 13 318 | 30. 6. 2024 |
0,11405 % | Raymond James & Associates, Inc. | 190 505 | 116 135 | 30. 9. 2024 |
0,11113 % | Rafferty Asset Management LLC | 185 637 | -98 715 | 30. 6. 2024 |
0,10177 % | Adage Capital Management, L.P. | 170 000 | -30 000 | 30. 6. 2024 |
0,09773 % | Readystate Asset Management LP | 163 241 | 95 941 | 30. 6. 2024 |
0,09479 % | Kelsey (Stephen Michael) | 158 345 | 0 | 14. 10. 2024 |
0,09467 % | Nicholas Investment Partners, L.P. | 158 132 | 142 044 | 30. 6. 2024 |
0,09223 % | T. Rowe Price International Ltd | 154 060 | 10 734 | 30. 6. 2024 |
0,08506 % | Neuberger Berman, LLC | 142 087 | -1 272 | 30. 6. 2024 |
0,08235 % | JPMorgan Private Bank (United States) | 137 559 | -1 373 | 30. 6. 2024 |
0,08065 % | Conestoga Capital Advisors, LLC | 134 721 | -1 296 | 31. 3. 2024 |
0,07962 % | Acuta Capital Partners, LLC | 133 000 | -10 777 | 30. 6. 2024 |
0,07899 % | J.P. Morgan Securities plc | 131 944 | 95 918 | 30. 6. 2024 |
0,07826 % | Legal & General Investment Management Ltd. | 130 725 | 24 596 | 30. 6. 2024 |