١٢٫٧٥٩٤١ % | Pontifax Venture Capital | ٤٬٧٨٧٬٣٣١ | -٧٬١٧٦ | ٣١/٣/٢٠٢٣ |
٩٫٥٩٨٧٦ % | Fidelity Management & Research Company LLC | ٣٬٦٠١٬٤٥٤ | ٢٩٬١١٣ | ٣١/١٢/٢٠٢٣ |
٤٫٥٩٧٢٩ % | BlackRock Institutional Trust Company, N.A. | ١٬٧٢٤٬٩٠٣ | ١٥٤٬٨٩٥ | ٣١/١٢/٢٠٢٣ |
٣٫٨٠٦٦٠ % | The Vanguard Group, Inc. | ١٬٤٢٨٬٢٣٧ | ٢٥٬٧٦٤ | ٣١/١٢/٢٠٢٣ |
٣٫٦٥٤٢٥ % | Arkin Bio Ventures LP | ١٬٣٧١٬٠٧٤ | -٤٤١٬٢٤١ | ٢٦/١/٢٠٢٣ |
٣٫٣٨١٤٩ % | OrbiMed Advisors, LLC | ١٬٢٦٨٬٧٣٤ | -٢٤٦٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
٣٫٣٤٨٦٧ % | Alkeon Capital Management LLC | ١٬٢٥٦٬٤٢١ | -١٧٧٬٦١٥ | ٣١/١٢/٢٠٢٣ |
٢٫٩٨٢٣١ % | Braidwell LP | ١٬١١٨٬٩٦١ | -٢٣٨٬٣٤٨ | ٣١/١٢/٢٠٢٣ |
٢٫٨٢٦٣٠ % | Darwin Global Management Ltd | ١٬٠٦٠٬٤٢٧ | ١٬٠٦٠٬٤٢٧ | ٣١/١٢/٢٠٢٣ |
٢٫٨١٠١٥ % | State Street Global Advisors (US) | ١٬٠٥٤٬٣٦٧ | ١٥٢٬٣٦٧ | ٣١/١٢/٢٠٢٣ |
٢٫٧٣٧٢٠ % | T. Rowe Price Associates, Inc. | ١٬٠٢٦٬٩٩٦ | -٢٢٥٬٩٤٣ | ٣١/١٢/٢٠٢٣ |
٢٫١٨٣٠٠ % | Candriam Belgium S.A. | ٨١٩٬٠٦٢ | ٧٨٬٠٠١ | ٣١/١٢/٢٠٢٣ |
٢٫٠٢٦٠٣ % | Citadel Advisors LLC | ٧٦٠٬١٦٨ | ٣٥٥٬٠١٩ | ٣١/١٢/٢٠٢٣ |
١٫٩٠٠٤٤ % | Candriam Luxembourg S.A. | ٧١٣٬٠٤٦ | -١٦٬٠٠٠ | ٢٩/٢/٢٠٢٤ |
١٫٨٩٩٧٨ % | Morgan Stanley & Co. LLC | ٧١٢٬٧٩٦ | ٣٥٣٬٤٩٤ | ٣١/١٢/٢٠٢٣ |
١٫٨٦٤١٠ % | Franklin Advisers, Inc. | ٦٩٩٬٤١١ | ٢٢٦٬٦٩٧ | ٣١/١٢/٢٠٢٣ |
١٫٨٣٤٥٣ % | Adar1 Capital Management LLC | ٦٨٨٬٣١٦ | ٦٨٨٬٣١٦ | ٣١/١٢/٢٠٢٣ |
١٫٥٥٥٩٥ % | Woodline Partners LP | ٥٨٣٬٧٩٢ | -١٣٤٬٦٣١ | ٣١/١٢/٢٠٢٣ |
١٫٥٤٥٨٤ % | Eventide Asset Management, LLC | ٥٨٠٬٠٠٠ | 0 | ٣١/١٢/٢٠٢٣ |
١٫٥٣٣٨٣ % | Partners Innovation Fund LLC | ٥٧٥٬٤٩٢ | ١٬١٩١ | ٣١/٣/٢٠٢٣ |
١٫٣٩١٦٠ % | Millennium Management LLC | ٥٢٢٬١٢٨ | ٣١٨٬٠٧١ | ٣١/١٢/٢٠٢٣ |
١٫٣٥٩٨٤ % | Geode Capital Management, L.L.C. | ٥١٠٬٢١١ | ٢٤٬٢١٠ | ٣١/١٢/٢٠٢٣ |
١٫٠٨٦٤٤ % | Cowen Investment Management LLC | ٤٠٧٬٦٣٣ | ٥٬٥١٥ | ٣٠/٩/٢٠٢٣ |
٠٫٩٦٠٧٣ % | Parkman Healthcare Partners LLC | ٣٦٠٬٤٦٧ | ٦١٬٩٩٢ | ٣١/١٢/٢٠٢٣ |
٠٫٩٥٢٨٣ % | Opaleye Management Inc. | ٣٥٧٬٥٠٠ | -٢٬٩٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٩٥١٦٤ % | DWS Investments UK Limited | ٣٥٧٬٠٥٥ | ٣٤٥٬٦٧٤ | ٣١/١٢/٢٠٢٣ |
٠٫٩٣٩٨٥ % | Blue Owl Capital Holdings LP | ٣٥٢٬٦٣٣ | ٣٥٢٬٦٣٣ | ٣١/١٢/٢٠٢٣ |
٠٫٨٢٦٦٠ % | Nantahala Capital Management, LLC | ٣١٠٬١٤١ | -١٨٬٦٤٠ | ٣١/١٢/٢٠٢٣ |
٠٫٧٢٦٩٥ % | Fidelity Institutional Asset Management | ٢٧٢٬٧٥٠ | ٢٤٠٬١٦٣ | ٣١/١٢/٢٠٢٣ |
٠٫٦٧٣٩٢ % | Seehra (Jasbir) | ٢٥٢٬٨٥٦ | ٤٬٠٠٠ | ٨/٤/٢٠٢٣ |
٠٫٦٤٦٢٨ % | Oppenheimer Asset Management Inc. | ٢٤٢٬٤٨٦ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫٥٩٨١٢ % | Barclays Bank PLC | ٢٢٤٬٤١٥ | ١٧٤٬٩٠٤ | ٣١/١٢/٢٠٢٣ |
٠٫٥٧١٩٥ % | American Century Investment Management, Inc. | ٢١٤٬٥٩٧ | ٥٢٣ | ٣١/١٢/٢٠٢٣ |
٠٫٥٥٨٧٣ % | Morgan Stanley Investment Management Inc. (US) | ٢٠٩٬٦٣٤ | ١٢٢٬٦٧٠ | ٣١/١٢/٢٠٢٣ |
٠٫٥٣٢٣٨ % | Northern Trust Investments, Inc. | ١٩٩٬٧٥٠ | ١٤٬١٦٣ | ٣١/١٢/٢٠٢٣ |
٠٫٥١٠٩٤ % | BofA Global Research (US) | ١٩١٬٧٠٤ | ١٣٧٬٩٥٧ | ٣١/١٢/٢٠٢٣ |
٠٫٤٨٧٠٦ % | BlackRock Financial Management, Inc. | ١٨٢٬٧٤٥ | ٦٧٩ | ٣١/١٢/٢٠٢٣ |
٠٫٤٨٣٩٥ % | Charles Schwab Investment Management, Inc. | ١٨١٬٥٧٨ | ٤٬٦٢٥ | ٣١/١٢/٢٠٢٣ |
٠٫٤٨٣٤٤ % | UBS Financial Services, Inc. | ١٨١٬٣٨٥ | ١٧٤٬٧٩٨ | ٣١/١٢/٢٠٢٣ |
٠٫٤٨١٥١ % | Goldman Sachs & Company, Inc. | ١٨٠٬٦٦٣ | ٩٨٬٠٢٣ | ٣١/١٢/٢٠٢٣ |
٠٫٤٥٥٣٦ % | Dimensional Fund Advisors, L.P. | ١٧٠٬٨٥٢ | -٤٢٥ | ٣١/١٢/٢٠٢٣ |
٠٫٤٥١٤٧ % | Citi Investment Research (US) | ١٦٩٬٣٩١ | ٧١٬٢٨٢ | ٣١/١٢/٢٠٢٣ |
٠٫٤١٢٢٢ % | WCM Investment Management | ١٥٤٬٦٦٤ | ٥٧٬١٢٢ | ٣١/١٢/٢٠٢٣ |
٠٫٢٥٤١٠ % | Schonfeld Strategic Advisors LLC | ٩٥٬٣٣٨ | ١٧٬٥٣٨ | ٣١/١٢/٢٠٢٣ |
٠٫٢٥٣٤٦ % | Lachey (Jennifer) | ٩٥٬١٠٠ | 0 | ١٥/٧/٢٠٢٢ |
٠٫٢٥٢٠٢ % | Russell Investments Trust Company | ٩٤٬٥٥٧ | ١٨٬٦٨٢ | ٣١/١٢/٢٠٢٣ |
٠٫٢٤١٠٤ % | Victory Capital Management Inc. | ٩٠٬٤٤٠ | ٣٤٬٤٦٩ | ٣١/١٢/٢٠٢٣ |
٠٫٢١٦٥٠ % | Point72 Asset Management, L.P. | ٨١٬٢٣٠ | -٦٨٬٥٠٣ | ٣١/١٢/٢٠٢٣ |
٠٫٢٠٠٤٥ % | Nuveen LLC | ٧٥٬٢٠٧ | ٤٬١٨٩ | ٣١/١٢/٢٠٢٣ |
٠٫١٩٨٩٦ % | Superstring Capital Management LP | ٧٤٬٦٤٩ | ٧٤٬٦٤٩ | ٣١/١٢/٢٠٢٣ |
٠٫١٩٨١٩ % | Dafna Capital Management, LLC | ٧٤٬٣٦١ | ٨٬٤٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫١٨٠٠٧ % | BNY Mellon Asset Management | ٦٧٬٥٦٤ | ٧٬٢٩٥ | ٣١/١٢/٢٠٢٣ |
٠٫١٧٣٩٩ % | Rafferty Asset Management LLC | ٦٥٬٢٨١ | ٧٬٠٩٢ | ٣١/١٢/٢٠٢٣ |
٠٫١٦٨١٠ % | Allianz Global Investors U.S. LLC_NLE | ٦٣٬٠٧٠ | 0 | ٣٠/٩/٢٠٢٣ |
٠٫١٥٢٠٧ % | BlackRock Advisors (UK) Limited | ٥٧٬٠٥٧ | ٣٬١٥١ | ٣١/٣/٢٠٢٤ |
٠٫١٤٨٣٧ % | BlackRock Investment Management, LLC | ٥٥٬٦٦٧ | ٩١٣ | ٣١/١٢/٢٠٢٣ |
٠٫١٣١٨٦ % | Marshall Wace LLP | ٤٩٬٤٧٢ | ٤٩٬٤٧٢ | ٣١/١٢/٢٠٢٣ |
٠٫١٣٠٢٩ % | Platinum Asset Management | ٤٨٬٨٨٣ | ٤٨٬٨٨٣ | ٣١/١٢/٢٠٢٣ |
٠٫١١٥٤٩ % | BlackRock Asset Management Ireland Limited | ٤٣٬٣٣١ | ٧٬٦٩٠ | ٣١/١٢/٢٠٢٣ |
٠٫١٠٩٠١ % | Schweizerische Nationalbank | ٤٠٬٩٠٠ | -٤٬٧٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٠٩٥١٥ % | Norges Bank Investment Management (NBIM) | ٣٥٬٧٠٠ | ٣٥٬٧٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٠٩٤٢٠ % | Barclays Capital Inc. | ٣٥٬٣٤٥ | ٣٥٬٣٤٥ | ٣١/١٢/٢٠٢٣ |
٠٫٠٩٢٠٦ % | Qube Research & Technologies Ltd | ٣٤٬٥٤٢ | ٢٥٬٥٨٤ | ٣١/١٢/٢٠٢٣ |
٠٫٠٨٩٦٥ % | Voya Investment Management LLC | ٣٣٬٦٣٥ | -٣٨٬٥١١ | ٣١/١٢/٢٠٢٣ |
٠٫٠٨٨٨١ % | Polen Capital Management, LLC | ٣٣٬٣٢١ | -٢٬٥٥٢ | ٢٩/٢/٢٠٢٤ |
٠٫٠٨٤٣٧ % | Rhumbline Advisers Ltd. Partnership | ٣١٬٦٥٧ | -٨٨٦ | ٣١/١٢/٢٠٢٣ |
٠٫٠٨٤١٥ % | Two Sigma Investments, LP | ٣١٬٥٧٢ | ٣١٬٥٧٢ | ٣١/١٢/٢٠٢٣ |
٠٫٠٧٧٠٠ % | State of Wisconsin Investment Board | ٢٨٬٨٩١ | ٢٬١٨٣ | ٣١/١٢/٢٠٢٣ |
٠٫٠٧١٠١ % | Credit Suisse Funds AG | ٢٦٬٦٤٢ | ٢٬٢٤٦ | ٣١/١٢/٢٠٢٣ |
٠٫٠٦٧٤٩ % | J.P. Morgan Securities plc | ٢٥٬٣٢٤ | ٣٧٢ | ٣١/١٢/٢٠٢٣ |
٠٫٠٦٥١٣ % | Goldman Sachs Asset Management, L.P. | ٢٤٬٤٣٦ | ٧٬٠١٧ | ٣١/١٢/٢٠٢٣ |
٠٫٠٦٥١٣ % | Allianz Global Investors GmbH | ٢٤٬٤٣٥ | 0 | ٣١/١/٢٠٢٤ |
٠٫٠٦١٧١ % | Assenagon Asset Management S.A. | ٢٣٬١٥٥ | ١٬٦٨٣ | ٢٩/٢/٢٠٢٤ |
٠٫٠٥٩١٨ % | California State Teachers Retirement System | ٢٢٬٢٠٣ | -١٬٠٦٤ | ٣١/١٢/٢٠٢٣ |
٠٫٠٥٦٢٩ % | AllianceBernstein L.P. | ٢١٬١٢٠ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫٠٥٥٦٠ % | BIT Capital GmbH | ٢٠٬٨٦٢ | ٢٠٬٨٦٢ | ٣١/١٢/٢٠٢٣ |
٠٫٠٥٢٢٧ % | Alps Advisors, Inc. | ١٩٬٦١٢ | -٢٬٢٨١ | ٣١/١٢/٢٠٢٣ |
٠٫٠٥١٧٥ % | Jane Street Capital, L.L.C. | ١٩٬٤١٧ | ٨٬٨١١ | ٣١/١٢/٢٠٢٣ |
٠٫٠٥١٣٢ % | Mellon Investments Corporation | ١٩٬٢٥٧ | -٤٦٬٥٣٤ | ٣١/١٢/٢٠٢٣ |
٠٫٠٥٠٣١ % | Legal & General Investment Management Ltd. | ١٨٬٨٧٦ | -٥٠ | ٣١/١٢/٢٠٢٣ |
٠٫٠٤٧٢١ % | Balyasny Asset Management LP | ١٧٬٧١٥ | -٢٧٬٢٧٤ | ٣١/١٢/٢٠٢٣ |
٠٫٠٤٢٩٢ % | B. Metzler seel. Sohn & Co AG | ١٦٬١٠٣ | ١٬٩٥٢ | ٣١/١٢/٢٠٢٣ |
٠٫٠٤٢٣٨ % | Jefferies LLC | ١٥٬٩٠٠ | ١٥٬٩٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٠٤١٤٠ % | Susquehanna International Group, LLP | ١٥٬٥٣٢ | ١٥٬٥٣٢ | ٣١/١٢/٢٠٢٣ |
٠٫٠٣٩٦٨ % | JPMorgan Private Bank (United States) | ١٤٬٨٨٨ | ١٤٬٨٨٨ | ٣١/١٢/٢٠٢٣ |
٠٫٠٣٩٢٠ % | Northern Trust Global Investments | ١٤٬٧٠٧ | -٦٬٤٠٧ | ٣١/١٢/٢٠٢٣ |
٠٫٠٣٩١٩ % | T. Rowe Price International Ltd | ١٤٬٧٠٥ | ٤١٢ | ٣١/١٢/٢٠٢٣ |
٠٫٠٣٧٦١ % | UBS O'Connor LLC | ١٤٬١١٢ | -٤٦٬٢٢٩ | ٣١/١٢/٢٠٢٣ |
٠٫٠٣٧٤٩ % | JP Morgan Asset Management | ١٤٬٠٦٦ | -١٤٬٠٥١ | ٣١/١٢/٢٠٢٣ |
٠٫٠٣٤٩٧ % | HRT Financial LP | ١٣٬١٢٢ | ١٣٬١٢٢ | ٣١/١٢/٢٠٢٣ |
٠٫٠٣٤٥٩ % | Putnam Investment Management, L.L.C. | ١٢٬٩٧٨ | ٣٬٢٥٧ | ٣١/١٢/٢٠٢٣ |
٠٫٠٣٤٣٨ % | Mirae Asset Global Investments (USA) LLC | ١٢٬٨٩٨ | ٤٠٤ | ٣١/١٢/٢٠٢٣ |
٠٫٠٣٢٦٥ % | SG Americas Securities, L.L.C. | ١٢٬٢٥٢ | -٣٤٬٩٣١ | ٣١/١٢/٢٠٢٣ |
٠٫٠٣١٦٨ % | MetLife Investment Management, LLC | ١١٬٨٨٥ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫٠٣٠٤٩ % | Manulife Investment Management (North America) Limited | ١١٬٤٤١ | -١٨٬٤٣٣ | ٣١/١٢/٢٠٢٣ |
٠٫٠٢٩٨٢ % | SunAmerica Asset Management, LLC | ١١٬١٨٨ | -٤٥ | ٣١/١٢/٢٠٢٣ |
٠٫٠٢٩٥٤ % | UBS Asset Management (Switzerland) | ١١٬٠٨٥ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫٠٢٩٢٦ % | BlackRock Investment Management (UK) Ltd. | ١٠٬٩٧٨ | -١٬٥٢٧ | ٣١/١٢/٢٠٢٣ |
٠٫٠٢٨٩١ % | ProFund Advisors LLC | ١٠٬٨٤٧ | ٨٢٦ | ٣١/١٢/٢٠٢٣ |
٠٫٠٢٨٣٤ % | Algert Global LLC | ١٠٬٦٣٥ | 0 | ٣١/١٢/٢٠٢٣ |