١٤٫٨٣٦٢٥ % | Vivo Capital, LLC | ٥٬٧٦٦٬٨٥١ | -١٬٥٥٠٬٠٠٠ | ٢٩/٨/٢٠٢٤ |
١٠٫٧١١٨٠ % | Janus Henderson Investors | ٤٬١٦٣٬٦٧٨ | ٨٠٤٬٨٠٥ | ٣٠/٩/٢٠٢٤ |
٨٫٢٤٥٣٧ % | Perceptive Advisors LLC | ٣٬٢٠٤٬٩٧٦ | ١٣٠٬٤٣٤ | ٣٠/٦/٢٠٢٤ |
٧٫٩٢٩٢٧ % | Nantahala Capital Management, LLC | ٣٬٠٨٢٬١٠٧ | ٦٧١٬٧٢٨ | ٣٠/٦/٢٠٢٤ |
٧٫٣٤٢٦٧ % | Adage Capital Management, L.P. | ٢٬٨٥٤٬٠٩٤ | ٩١٠٬٥٧٤ | ٣٠/٦/٢٠٢٤ |
٥٫٣٨١١٨ % | Avoro Capital Advisors LLC | ٢٬٠٩١٬٦٦٦ | ٤٦٦٬٦٦٦ | ٣٠/٦/٢٠٢٤ |
٣٫٨٥٧١٧ % | The Vanguard Group, Inc. | ١٬٤٩٩٬٢٨٣ | ٥٣٣٬٠٩٨ | ٣٠/٦/٢٠٢٤ |
٣٫٦٦٦٠٧ % | Commodore Capital LP | ١٬٤٢٥٬٠٠٠ | ١٬٢٥٥٬٤٦٧ | ٣٠/٦/٢٠٢٤ |
٣٫٦٣٩٤٠ % | BlackRock Institutional Trust Company, N.A. | ١٬٤١٤٬٦٣٣ | ١٬١١٥٬٤٣٧ | ٣٠/٦/٢٠٢٤ |
٣٫٠٨٧٢١ % | Vestal Point Capital, LP | ١٬٢٠٠٬٠٠٠ | -٥٠٬٠٠٠ | ٣٠/٦/٢٠٢٤ |
٢٫٥٧٣٠٣ % | State Street Global Advisors (US) | ١٬٠٠٠٬١٣٦ | ٢٩٬٥٦٦ | ٣٠/٦/٢٠٢٤ |
٢٫٢٥٢٨١ % | Frazier Life Sciences Management, L.P. | ٨٧٥٬٦٦٧ | 0 | ٣٠/٦/٢٠٢٤ |
١٫٨٦٧٤٦ % | Abingworth Management Limited | ٧٢٥٬٨٨١ | -٢٬١٣١٬٩٢٣ | ١٧/١٠/٢٠٢٤ |
١٫٦١٠٥٩ % | Anish (Bhatnagar) | ٦٢٦٬٠٣٥ | -٢١٬٦٣٣ | ١/١٠/٢٠٢٤ |
١٫٤٢٦١٩ % | Sofinnova Investments, Inc | ٥٥٤٬٣٥٩ | ٤٠٣٬٥٨٤ | ٣٠/٦/٢٠٢٤ |
١٫٤١٤٩٧ % | TCG Crossover Management, LLC | ٥٥٠٬٠٠٠ | 0 | ٣٠/٦/٢٠٢٤ |
١٫٤٠٥٥٦ % | Emerald Advisers LLC | ٥٤٦٬٣٤٢ | ١١٬٩١٥ | ٣٠/٩/٢٠٢٤ |
١٫٣٨٠١٢ % | Holocene Advisors, LP | ٥٣٦٬٤٥١ | ٥٣٦٬٤٥١ | ٣٠/٦/٢٠٢٤ |
١٫٢٨٩٠٤ % | Samlyn Capital, LLC | ٥٠١٬٠٤٩ | ٢٨٢٬١٢٢ | ٣٠/٦/٢٠٢٤ |
١٫٢٥٨٣١ % | Geode Capital Management, L.L.C. | ٤٨٩٬١٠٧ | ٣٢٢٬٠٨٦ | ٣٠/٦/٢٠٢٤ |
١٫١٨٧٩٧ % | T. Rowe Price Associates, Inc. | ٤٦١٬٧٦٢ | ٣٠٩٬١٤٢ | ٣٠/٦/٢٠٢٤ |
١٫١٧٩٦٢ % | Millennium Management LLC | ٤٥٨٬٥٢٠ | ٣٦٦٬٢٩٥ | ٣٠/٦/٢٠٢٤ |
١٫١٤٦٠٠ % | Ikarian Capital LLC | ٤٤٥٬٤٥١ | -١١٩٬٩٦٠ | ٣٠/٦/٢٠٢٤ |
١٫١١٠٧٨ % | Pictet Asset Management Ltd. | ٤٣١٬٧٦٠ | ٩٧٬٩٠٨ | ٣٠/٦/٢٠٢٤ |
١٫٠١١١٥ % | Wellington Management Company, LLP | ٣٩٣٬٠٣٥ | ٣٩٬٥٥٤ | ٣٠/٦/٢٠٢٤ |
٠٫٨٦٤٧١ % | BlackRock Financial Management, Inc. | ٣٣٦٬١١٤ | ٣٣٠٬٧٢٣ | ٣٠/٦/٢٠٢٤ |
٠٫٨٢١٢١ % | Woodline Partners LP | ٣١٩٬٢٠٥ | ٢١٢٬٧٤٥ | ٣٠/٦/٢٠٢٤ |
٠٫٧٧١٨٠ % | Ghost Tree Capital, LLC | ٣٠٠٬٠٠٠ | ١٠٠٬٠٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫٧٣٦٢٠ % | Ally Bridge Group NY LLC | ٢٨٦٬١٦٢ | -٥٠٬٣٢٤ | ٣٠/٦/٢٠٢٤ |
٠٫٦٣٦٠٠ % | Balyasny Asset Management LP | ٢٤٧٬٢١٤ | ٩٥٬٥٩٦ | ٣٠/٦/٢٠٢٤ |
٠٫٥٥٠٠٨ % | Mario (Ernest B) | ٢١٣٬٨١٨ | ٦٬٥٠٠ | ٦/٦/٢٠٢٤ |
٠٫٥٤٧٧٥ % | Altium Capital Management LP | ٢١٢٬٩٠٩ | ٦٠٬٠٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫٥١٧٢١ % | Goldman Sachs & Company, Inc. | ٢٠١٬٠٣٨ | -١٠٬٨٧٩ | ٣٠/٦/٢٠٢٤ |
٠٫٥٠٧٧١ % | Medical Strategy GmbH | ١٩٧٬٣٤٧ | ٢٥٬٠٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫٣٧٣٥٧ % | Schuler (Jack W) | ١٤٥٬٢٠٧ | -٣٧٢٬١٤٣ | ٢٤/٥/٢٠٢٣ |
٠٫٣٧٣٣٢ % | Driehaus Capital Management, LLC | ١٤٥٬١١٠ | ٥١٬٦٥٦ | ٣٠/٦/٢٠٢٤ |
٠٫٣٦٣٨٤ % | Allspring Global Investments, LLC | ١٤١٬٤٢٤ | ٧٬٨٤٠ | ٣٠/٩/٢٠٢٤ |
٠٫٢٨٢٩٩ % | Soros Fund Management, L.L.C. | ١١٠٬٠٠٠ | ١٠٬٠٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫٢٦٧٦١ % | Boothbay Fund Management, LLC | ١٠٤٬٠٢٠ | -٢٨٬٠١١ | ٣٠/٦/٢٠٢٤ |
٠٫٢٤٢٩٢ % | Artia Global Partners LP | ٩٤٬٤٢٤ | ٥٣٬٥٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫٢٣٣٠٣ % | Principal Global Investors (Equity) | ٩٠٬٥٨٠ | -٦٬٤٨٣ | ٣١/٨/٢٠٢٤ |
٠٫٢١٥٤٠ % | Caption Management, LLC | ٨٣٬٧٢٦ | ٤٣٬٧٢٦ | ٣٠/٦/٢٠٢٤ |
٠٫٢١٥٣٢ % | Morgan Stanley & Co. LLC | ٨٣٬٦٩٦ | ٤٬٥٠٩ | ٣٠/٦/٢٠٢٤ |
٠٫٢١٣٩٣ % | Hirano (Patricia C) | ٨٣٬١٥٣ | -٣٬١٠٨ | ١/١٠/٢٠٢٤ |
٠٫٢١١٨٥ % | Mackaness (James H) | ٨٢٬٣٤٨ | -٨٬٠٧٧ | ١/١٠/٢٠٢٤ |
٠٫٢٠٩٥٩ % | Yen (Kristen) | ٨١٬٤٦٦ | -٣٬١٠٨ | ١/١٠/٢٠٢٤ |
٠٫١٩١٦٦ % | Polar Asset Management Partners Inc. | ٧٤٬٥٠٠ | ٧٤٬٥٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫١٨٠٠٩ % | 683 Capital Management LLC | ٧٠٬٠٠٠ | -٨٬٠٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫١٧١٣٧ % | BofA Global Research (US) | ٦٦٬٦١٢ | -٢٬٣٤٦ | ٣٠/٦/٢٠٢٤ |
٠٫١٦١٧٣ % | BlackRock Investment Management, LLC | ٦٢٬٨٦٣ | ٦٢٬٨٦٣ | ٣٠/٦/٢٠٢٤ |
٠٫١٦٠٨٤ % | Charles Schwab Investment Management, Inc. | ٦٢٬٥١٧ | ٥٥٬٣٢٢ | ٣٠/٦/٢٠٢٤ |
٠٫١٥٠٤٠ % | Nuveen LLC | ٥٨٬٤٦٠ | ٥٨٬٤٦٠ | ٣٠/٦/٢٠٢٤ |
٠٫١٤٨٦٢ % | Norges Bank Investment Management (NBIM) | ٥٧٬٧٧٠ | ٥٧٬٧٧٠ | ٣٠/٦/٢٠٢٤ |
٠٫١٤٨٠٢ % | TD Asset Management Inc. | ٥٧٬٥٣٤ | ٣٦٬٥٣٤ | ٣٠/٦/٢٠٢٤ |
٠٫١٤٤٨٨ % | Qube Research & Technologies Ltd | ٥٦٬٣١٦ | -٢٢٬١٨٤ | ٣٠/٦/٢٠٢٤ |
٠٫١٤٤٠١ % | Northern Trust Investments, Inc. | ٥٥٬٩٧٨ | ٢٢٬٤٠١ | ٣٠/٦/٢٠٢٤ |
٠٫١٤٣٨٣ % | BNY Mellon Asset Management | ٥٥٬٩٠٦ | ٥٥٬٩٠٦ | ٣٠/٦/٢٠٢٤ |
٠٫١٣٨٩٧ % | Schonfeld Strategic Advisors LLC | ٥٤٬٠١٩ | ٨٬٥٤٧ | ٣٠/٦/٢٠٢٤ |
٠٫١٣٨٧٦ % | Rafferty Asset Management LLC | ٥٣٬٩٣٧ | -٥٢٬٢٠٧ | ٣٠/٦/٢٠٢٤ |
٠٫١٢٧١١ % | Manulife Investment Management (North America) Limited | ٤٩٬٤٠٨ | ٢٧٬٠٢٠ | ٣٠/٦/٢٠٢٤ |
٠٫١٠٢٩١ % | Manning (Meredith S.) | ٤٠٬٠٠٠ | ٤٠٬٠٠٠ | ١٧/٧/٢٠٢٤ |
٠٫١٠٢٧٢ % | Adar1 Capital Management LLC | ٣٩٬٩٢٩ | ٣٩٬٩٢٩ | ٣٠/٦/٢٠٢٤ |
٠٫١٠٠٨١ % | Susquehanna International Group, LLP | ٣٩٬١٨٤ | ٣٠٬١٦٢ | ٣٠/٦/٢٠٢٤ |
٠٫٠٩٢٧٤ % | Harbor Capital Advisors, Inc. | ٣٦٬٠٤٨ | ٣٤٬٨٠٧ | ٣٠/٩/٢٠٢٤ |
٠٫٠٩٠٢٨ % | Jefferies LLC | ٣٥٬٠٩١ | -٨٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫٠٩٠٠٤ % | Huang (Michael F) | ٣٥٬٠٠٠ | ٣٥٬٠٠٠ | ١٧/٧/٢٠٢٤ |
٠٫٠٨٧٣٤ % | UBS Financial Services, Inc. | ٣٣٬٩٥٠ | -١٩٬٨٥٥ | ٣٠/٦/٢٠٢٤ |
٠٫٠٨٦٥٠ % | Columbia Threadneedle Investments (US) | ٣٣٬٦٢٤ | ٢٬٤٨٤ | ٣٠/٦/٢٠٢٤ |
٠٫٠٨٤٥٣ % | Mellon Investments Corporation | ٣٢٬٨٥٨ | ٣٢٬٨٥٨ | ٣٠/٦/٢٠٢٤ |
٠٫٠٨١١٧ % | MFS Investment Management | ٣١٬٥٥٠ | 0 | ٣١/٨/٢٠٢٤ |
٠٫٠٨٠٨٢ % | BlackRock Investment Management (UK) Ltd. | ٣١٬٤١٤ | ٢٥٬٠٤٤ | ٣٠/٦/٢٠٢٤ |
٠٫٠٧٧١٨ % | Hudson Bay Capital Management LP | ٣٠٬٠٠٠ | ٣٠٬٠٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫٠٧٤٩٨ % | Rhumbline Advisers Ltd. Partnership | ٢٩٬١٤٤ | ٢٩٬١٤٤ | ٣٠/٦/٢٠٢٤ |
٠٫٠٧٤٠٩ % | Schweizerische Nationalbank | ٢٨٬٨٠٠ | -١٬٣٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫٠٧٣٠٧ % | Alps Advisors, Inc. | ٢٨٬٤٠١ | ٦٬٨٨٧ | ٣٠/٦/٢٠٢٤ |
٠٫٠٦٩٣٠ % | J. Goldman & Co., L.P. | ٢٦٬٩٣٨ | ٢٦٬٩٣٨ | ٣٠/٦/٢٠٢٤ |
٠٫٠٦٤٣٢ % | Maplelane Capital, LLC | ٢٥٬٠٠٠ | 0 | ٣٠/٦/٢٠٢٤ |
٠٫٠٦٣٣١ % | AllianceBernstein L.P. | ٢٤٬٦١٠ | ٢٤٬٦١٠ | ٣٠/٦/٢٠٢٤ |
٠٫٠٥٤٢٣ % | Barclays Bank PLC | ٢١٬٠٧٨ | ٤٥٩ | ٣٠/٦/٢٠٢٤ |
٠٫٠٥٣٥٧ % | Alpine Global Management, LLC | ٢٠٬٨٢٤ | ٢٠٬٨٢٤ | ٣٠/٦/٢٠٢٤ |
٠٫٠٥٠٦٧ % | Checkpoint Capital L.P. | ١٩٬٦٩٥ | ١٩٬٦٩٥ | ٣٠/٦/٢٠٢٤ |
٠٫٠٤٦٢٣ % | BlackRock Asset Management Ireland Limited | ١٧٬٩٧٠ | ٢٬٦٢٩ | ٣٠/٦/٢٠٢٤ |
٠٫٠٤٥٥٤ % | Tudor Investment Corporation | ١٧٬٧٠٢ | ١٬٥٠٨ | ٣٠/٦/٢٠٢٤ |
٠٫٠٤٤٩٠ % | Legal & General Investment Management Ltd. | ١٧٬٤٥٢ | ٥٬١٦٩ | ٣٠/٦/٢٠٢٤ |
٠٫٠٤١٣٩ % | T. Rowe Price International Ltd | ١٦٬٠٩٠ | ١١٬٢٢٨ | ٣٠/٦/٢٠٢٤ |
٠٫٠٣٩٦٢ % | Harris (William G) | ١٥٬٤٠١ | ٦٬٥٠٠ | ٦/٦/٢٠٢٤ |
٠٫٠٣٨٥٩ % | SilverArc Capital Management, LLC | ١٥٬٠٠٠ | ١٥٬٠٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫٠٣٨٥٩ % | UBS O'Connor LLC | ١٥٬٠٠٠ | ١٥٬٠٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫٠٣٨١٥ % | California State Teachers Retirement System | ١٤٬٨٢٧ | ١٬٠٤٧ | ٣٠/٦/٢٠٢٤ |
٠٫٠٣٦٢٠ % | Jane Street Capital, L.L.C. | ١٤٬٠٧٠ | -٧٦٨ | ٣٠/٦/٢٠٢٤ |
٠٫٠٣٤٨٥ % | Volck (Birgitte) | ١٣٬٥٤٥ | ٦٬٥٠٠ | ٦/٦/٢٠٢٤ |
٠٫٠٣٣٩٣ % | Cinctive Capital Management LP | ١٣٬١٩٠ | ١٣٬١٩٠ | ٣٠/٦/٢٠٢٤ |
٠٫٠٣٣٤٤ % | Bir (Dawn Carter) | ١٣٬٠٠٠ | ١٣٬٠٠٠ | ١٥/٨/٢٠٢٤ |
٠٫٠٣٣٣٢ % | NEOS Investment Management, LLC | ١٢٬٩٥٠ | ١٬٣١١ | ٣٠/٦/٢٠٢٤ |
٠٫٠٣١٢٠ % | Aspiriant, LLC | ١٢٬١٢٨ | 0 | ٣٠/٩/٢٠٢٤ |
٠٫٠٣٠٤٤ % | Corebridge Financial Inc | ١١٬٨٣٢ | ١١٬٨٣٢ | ٣٠/٦/٢٠٢٤ |
٠٫٠٣٠٤٤ % | SunAmerica Asset Management, LLC | ١١٬٨٣٢ | 0 | ٣١/٧/٢٠٢٤ |
٠٫٠٢٨١٧ % | Citi Investment Research (US) | ١٠٬٩٤٨ | -٨٦٬٨٠٦ | ٣٠/٦/٢٠٢٤ |
٠٫٠٢٧٦٠ % | Victory Capital Management Inc. | ١٠٬٧٢٧ | ٢٬٢٣٦ | ٣٠/٦/٢٠٢٤ |
٠٫٠٢٧٣٣ % | Invesco Advisers, Inc. | ١٠٬٦٢٥ | ١٠٬٢٦٢ | ٣٠/٦/٢٠٢٤ |