١٥٫٠٠٠٦٨ % | Fidelity Management & Research Company LLC | ٧٬٥١٣٬٨٤٠ | ٨٬٤٢٦ | ٣٠/٦/٢٠٢٤ |
٩٫٩٤٧٩٨ % | EcoR1 Capital, LLC | ٤٬٩٨٢٬٩٤٥ | ١٬٩٦٨٬١٩٣ | ٣٠/٦/٢٠٢٤ |
٦٫٠٤١٣٩ % | Springer Timothy A | ٣٬٠٢٦٬١٣٣ | -٤٬٦٠٨٬٠٥٢ | ١٦/٨/٢٠٢٤ |
٥٫٨٧٦١٦ % | BlackRock Institutional Trust Company, N.A. | ٢٬٩٤٣٬٣٧١ | ١٧٥٬٤٤٦ | ٣٠/٦/٢٠٢٤ |
٥٫٠٤٢٩٢ % | Invus Public Equities Advisors, LLC | ٢٬٥٢٥٬٩٩٨ | ٣١٢٬٨١٠ | ٣٠/٦/٢٠٢٤ |
٤٫٤١٢٩١ % | The Vanguard Group, Inc. | ٢٬٢١٠٬٤٢٩ | -٤٥٬٢٤٦ | ٣٠/٦/٢٠٢٤ |
٤٫٢٩٦٥٠ % | T. Rowe Price Associates, Inc. | ٢٬١٥٢٬١١٧ | -٣١٨٬٠٤٢ | ٣٠/٦/٢٠٢٤ |
٣٫٩٧٤١٥ % | Polaris Venture Partners | ١٬٩٩٠٬٦٥١ | 0 | ١/٤/٢٠٢٤ |
٣٫٥٦٠٠٠ % | Woodline Partners LP | ١٬٧٨٣٬٢٠٢ | ١٬٦٨٣٬٢٠٢ | ٣٠/٦/٢٠٢٤ |
٣٫٢٧٠٣٣ % | State Street Global Advisors (US) | ١٬٦٣٨٬١٠٨ | -١٬٠٢٧٬٤٠٢ | ٣٠/٦/٢٠٢٤ |
٢٫٩١٧٣٥ % | Point72 Asset Management, L.P. | ١٬٤٦١٬٣٠٢ | -٣٬٢٢٥٬٧٩٨ | ٣٠/٦/٢٠٢٤ |
٢٫٠٣٢١٧ % | Pictet Asset Management Ltd. | ١٬٠١٧٬٩١٢ | -١٦٨٬٩٩٦ | ٣٠/٦/٢٠٢٤ |
١٫٩٨٦٤٢ % | Federated Hermes Global Investment Management Corp. | ٩٩٥٬٠٠٠ | 0 | ٣٠/٦/٢٠٢٤ |
١٫٩٣٦٤٩ % | Geode Capital Management, L.L.C. | ٩٦٩٬٩٨٦ | ٧٤٬٧٨٦ | ٣٠/٦/٢٠٢٤ |
١٫٢٢٦٧٤ % | Tipirneni (Praveen P) | ٦١٤٬٤٧٤ | -٤٢٬٤٦٠ | ١٦/٨/٢٠٢٤ |
١٫٢٢٢٨٠ % | OrbiMed Advisors, LLC | ٦١٢٬٥٠٠ | ٥٤٬٠٠٠ | ٣٠/٦/٢٠٢٤ |
١٫١٥٣٩٦ % | Two Sigma Investments, LP | ٥٧٨٬٠٢٠ | -٦٣٬٨٣١ | ٣٠/٦/٢٠٢٤ |
١٫٠٦٧٣٤ % | Goldman Sachs & Company, Inc. | ٥٣٤٬٦٣٠ | ١٠٣٬٩٢٥ | ٣٠/٦/٢٠٢٤ |
٠٫٩٧٠٨٦ % | SilverArc Capital Management, LLC | ٤٨٦٬٣٠٦ | ٢٬٣٣٤ | ٣٠/٦/٢٠٢٤ |
٠٫٧٣٧٤٤ % | MPM BioImpact LLC | ٣٦٩٬٣٨٤ | ٤٤٬٠٥١ | ٣٠/٦/٢٠٢٤ |
٠٫٦٥٤٥١ % | Charles Schwab Investment Management, Inc. | ٣٢٧٬٨٤٤ | ١٬١٤٧ | ٣٠/٦/٢٠٢٤ |
٠٫٦٤٥٦٤ % | BlackRock Financial Management, Inc. | ٣٢٣٬٤٠٣ | ٢٧٬٩٠٥ | ٣٠/٦/٢٠٢٤ |
٠٫٦٢٨٠٢ % | Northern Trust Investments, Inc. | ٣١٤٬٥٧٥ | -٦٤٦ | ٣٠/٦/٢٠٢٤ |
٠٫٥٠٠٢٥ % | Affinity Asset Advisors LLC | ٢٥٠٬٥٧٣ | ٢٥٬٥٧٣ | ٣٠/٦/٢٠٢٤ |
٠٫٤٨٨٩٨ % | Wellington Management Company, LLP | ٢٤٤٬٩٣١ | -٥٬٥٦٩٬٥١٥ | ٣١/٧/٢٠٢٤ |
٠٫٤٦٢٦٦ % | Dafna Capital Management, LLC | ٢٣١٬٧٤٨ | 0 | ٣٠/٦/٢٠٢٤ |
٠٫٤٢٧٩٦ % | Fiduciary Trust Company | ٢١٤٬٣٦٦ | 0 | ٣٠/٦/٢٠٢٤ |
٠٫٤٢٧٥٤ % | Candriam Belgium S.A. | ٢١٤٬١٥٤ | -٣٥٬٧٧٩ | ٣٠/٦/٢٠٢٤ |
٠٫٤١٥٧٠ % | Dimensional Fund Advisors, L.P. | ٢٠٨٬٢٢٥ | -١٢٬٩٣٧ | ٣٠/٦/٢٠٢٤ |
٠٫٣٢٣٣٩ % | Citadel Advisors LLC | ١٦١٬٩٨٨ | -٧٠٤٬٩١٠ | ٣٠/٦/٢٠٢٤ |
٠٫٣٢١٢١ % | Voloridge Investment Management, LLC | ١٦٠٬٨٩٦ | ١٦٠٬٨٩٦ | ٣٠/٦/٢٠٢٤ |
٠٫٣١٩١٢ % | Omega Fund Management, LLC | ١٥٩٬٨٤٦ | 0 | ٣٠/٦/٢٠٢٤ |
٠٫٣٠٥٠٩ % | D. E. Shaw & Co., L.P. | ١٥٢٬٨١٩ | -٦١٬٦٣٧ | ٣٠/٦/٢٠٢٤ |
٠٫٣٠٠٥٧ % | AllianceBernstein L.P. | ١٥٠٬٥٥٨ | ٣٨٬٧٧٦ | ٣٠/٦/٢٠٢٤ |
٠٫٢٩٢٠٧ % | Nomura Asset Management Co., Ltd. | ١٤٦٬٣٠٠ | ١٤٦٬٣٠٠ | ٣٠/١١/٢٠٢٣ |
٠٫٢٦٩٦٨ % | Morgan Stanley & Co. LLC | ١٣٥٬٠٨٢ | -٦٧٬٤٦٨ | ٣٠/٦/٢٠٢٤ |
٠٫٢٦٢٠٨ % | Jane Street Capital, L.L.C. | ١٣١٬٢٧٦ | ٨٥٬٣١٤ | ٣٠/٦/٢٠٢٤ |
٠٫٢٥٨٩٣ % | Nuveen LLC | ١٢٩٬٦٩٨ | ٣٬٨٩٧ | ٣٠/٦/٢٠٢٤ |
٠٫٢٥٧٤٦ % | Medical Strategy GmbH | ١٢٨٬٩٦٢ | -٣١٣٬٠٥١ | ٣١/١٢/٢٠٢٣ |
٠٫٢٣٥١٦ % | BlackRock Investment Management, LLC | ١١٧٬٧٩٤ | ٢٤٬٢٣٧ | ٣٠/٦/٢٠٢٤ |
٠٫٢٢٧٣٦ % | Ensign Peak Advisors, Inc. | ١١٣٬٨٨٣ | -٢٧٬٣٤٠ | ٣٠/٦/٢٠٢٤ |
٠٫٢٢٣٨٠ % | TD Asset Management Inc. | ١١٢٬١٠٠ | -١٣٬٨٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫١٩٧٥٣ % | Goldman Sachs Asset Management, L.P. | ٩٨٬٩٤٣ | -١٤٬٢٩٧ | ٣٠/٦/٢٠٢٤ |
٠٫١٩٢١٧ % | BNY Mellon Asset Management | ٩٦٬٢٥٦ | ٥٬٨١٩ | ٣٠/٦/٢٠٢٤ |
٠٫١٧٧٢١ % | Barclays Bank PLC | ٨٨٬٧٦٦ | ٤٤٬٠٣٩ | ٣٠/٦/٢٠٢٤ |
٠٫١٧١٦٢ % | Manulife Investment Management (North America) Limited | ٨٥٬٩٦٦ | ٤٬٠٢١ | ٣٠/٦/٢٠٢٤ |
٠٫١٧١٥٦ % | Susquehanna International Group, LLP | ٨٥٬٩٣٢ | ١٦٬٠٣٣ | ٣٠/٦/٢٠٢٤ |
٠٫١٦٨١٤ % | BofA Global Research (US) | ٨٤٬٢٢٣ | -٣٠٬٣٣٩ | ٣٠/٦/٢٠٢٤ |
٠٫١٥٩٨١ % | Allianz Global Investors GmbH | ٨٠٬٠٤٩ | -١٣٬٦٢١ | ٣٠/٦/٢٠٢٤ |
٠٫١٥٨٧٩ % | Jump Financial, LLC | ٧٩٬٥٣٩ | ٦٧٬٣٨٧ | ٣٠/٦/٢٠٢٤ |
٠٫١٥٥٢٥ % | Capital Fund Management S.A. | ٧٧٬٧٦٧ | ٥٨٬١٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫١٤٨٨٥ % | Rafferty Asset Management LLC | ٧٤٬٥٥٧ | -١٤٦٬٢٣٧ | ٣٠/٦/٢٠٢٤ |
٠٫١٤٥٧٤ % | HOOPP Investment Management | ٧٣٬٠٠٠ | ٧٣٬٠٠٠ | ٣٠/٦/٢٠٢٤ |
٠٫١٣٣٠٢ % | Atom Investors LP | ٦٦٬٦٢٨ | -٢٠٬٠٠٢ | ٣٠/٦/٢٠٢٤ |
٠٫١٣٠٥٢ % | Rhumbline Advisers Ltd. Partnership | ٦٥٬٣٧٩ | ١٣٬٦٧٧ | ٣٠/٦/٢٠٢٤ |
٠٫١٢٥٣٠ % | BlackRock Asset Management Ireland Limited | ٦٢٬٧٦٥ | ٣٬١٥٠ | ٣٠/٦/٢٠٢٤ |
٠٫١١٧٥٩ % | Schweizerische Nationalbank | ٥٨٬٩٠٠ | 0 | ٣٠/٦/٢٠٢٤ |
٠٫١١٥٧٢ % | Connor, Clark & Lunn Investment Management Ltd. | ٥٧٬٩٦٥ | -٤٦٬٦٦٥ | ٣٠/٦/٢٠٢٤ |
٠٫١٠٩٩٤ % | T. Rowe Price International Ltd | ٥٥٬٠٧٠ | ١٬٦٤٣ | ٣٠/٦/٢٠٢٤ |
٠٫١٠٧٧٣ % | Mellon Investments Corporation | ٥٣٬٩٦٣ | ٢١٬٦٥١ | ٣٠/٦/٢٠٢٤ |
٠٫١٠٧٣٠ % | PGIM Quantitative Solutions LLC | ٥٣٬٧٤٧ | -٢٦٬١٨٠ | ٣٠/٦/٢٠٢٤ |
٠٫٠٩٥١٥ % | Saturn V Capital Management LP | ٤٧٬٦٦٠ | -٣٧٬٩٧٢ | ٣٠/٦/٢٠٢٤ |
٠٫٠٨٦٢٨ % | BlackRock Investment Management (UK) Ltd. | ٤٣٬٢٢٠ | ٩٬٥١٦ | ٣٠/٦/٢٠٢٤ |
٠٫٠٨٢٧٧ % | UBS Financial Services, Inc. | ٤١٬٤٦٠ | -١٠٧٬٥٣٤ | ٣٠/٦/٢٠٢٤ |
٠٫٠٧٧٩٧ % | Alps Advisors, Inc. | ٣٩٬٠٥٤ | ٣٬٧٦٢ | ٣٠/٦/٢٠٢٤ |
٠٫٠٦٨١٣ % | Millennium Management LLC | ٣٤٬١٢٥ | ٣٤٬١٢٥ | ٣٠/٦/٢٠٢٤ |
٠٫٠٦٦١٠ % | Algert Global LLC | ٣٣٬١٠٨ | ١٦٬٥٣١ | ٣٠/٦/٢٠٢٤ |
٠٫٠٦٣٣٩ % | Wellington Management Singapore Pte. Ltd. | ٣١٬٧٥١ | ٣١٬٧٥١ | ٣١/٣/٢٠٢٤ |
٠٫٠٦٣٣٩ % | Wellington Management Japan Pte Ltd | ٣١٬٧٥١ | -١٣٬٤٤٧ | ٣٠/٦/٢٠٢٣ |
٠٫٠٥٩٩٩ % | California State Teachers Retirement System | ٣٠٬٠٤٨ | -٦٣١ | ٣٠/٦/٢٠٢٤ |
٠٫٠٥٩٦٨ % | Carmignac Gestion | ٢٩٬٨٩٢ | ٢٩٬٨٩٢ | ٣١/٧/٢٠٢٤ |
٠٫٠٥٨٣٢ % | Legal & General Investment Management Ltd. | ٢٩٬٢١٤ | -١٨٥ | ٣٠/٦/٢٠٢٤ |
٠٫٠٥٦٩٤ % | Victory Capital Management Inc. | ٢٨٬٥٢٠ | -٥٨٠ | ٣٠/٦/٢٠٢٤ |
٠٫٠٥٦٦٠ % | UBS Asset Management (Americas), Inc. | ٢٨٬٣٥٠ | ٢٨٬٣٥٠ | ٣١/٣/٢٠٢٣ |
٠٫٠٥٣٦٤ % | First Trust Advisors L.P. | ٢٦٬٨٦٧ | ٢٦٬٨٦٧ | ٣٠/٦/٢٠٢٤ |
٠٫٠٥٢٨٥ % | PDT Partners, LLC | ٢٦٬٤٧٤ | -٣٤٬٦٦٣ | ٣٠/٦/٢٠٢٤ |
٠٫٠٤٩٩١ % | Tudor Investment Corporation | ٢٥٬٠٠٢ | -٨٨٢ | ٣٠/٦/٢٠٢٤ |
٠٫٠٤٩٥١ % | T. Rowe Price Japan, Inc. | ٢٤٬٧٩٩ | ١٥٬٥٠٠ | ٣٠/٤/٢٠٢٤ |
٠٫٠٤٨٧٧ % | Aperio Group, LLC | ٢٤٬٤٢٧ | ٦٢٩ | ٣٠/٦/٢٠٢٤ |
٠٫٠٤٨٧٣ % | Northern Trust Global Investments | ٢٤٬٤٠٩ | ١٬١٠٦ | ٣٠/٦/٢٠٢٤ |
٠٫٠٤٨٥٥ % | UBS Fund Management (Switzerland) AG | ٢٤٬٣١٩ | -٧٬٩٠٤ | ٣٠/٦/٢٠٢٤ |
٠٫٠٤٧٨٩ % | Mirae Asset Global Investments (USA) LLC | ٢٣٬٩٨٦ | ٤٬٦٩٨ | ٣٠/٦/٢٠٢٤ |
٠٫٠٤٧٣٦ % | Squarepoint Capital LLP | ٢٣٬٧٢٣ | ٢٣٬٧٢٣ | ٣٠/٦/٢٠٢٤ |
٠٫٠٤٦١٨ % | American Century Investment Management, Inc. | ٢٣٬١٣٤ | ١٦٬٦٠٦ | ٣٠/٦/٢٠٢٤ |
٠٫٠٤٦٠٧ % | MetLife Investment Management, LLC | ٢٣٬٠٧٧ | ٣٬٦٦٥ | ٣٠/٦/٢٠٢٤ |
٠٫٠٤٤٢٥ % | DeVaul (William David) | ٢٢٬١٦٧ | 0 | ٨/٧/٢٠٢٤ |
٠٫٠٤٢٨٤ % | Y-Intercept (Hong Kong) Ltd | ٢١٬٤٥٩ | ٢١٬٤٥٩ | ٣٠/٦/٢٠٢٤ |
٠٫٠٤٢٧٨ % | Corebridge Financial Inc | ٢١٬٤٣١ | ٢١٬٤٣١ | ٣٠/٦/٢٠٢٤ |
٠٫٠٤٠٣٣ % | Healthinvest Partners AB | ٢٠٬١٩٩ | ٥٬٢٤٧ | ٣٠/٦/٢٠٢٤ |
٠٫٠٣٨٥٩ % | ExodusPoint Capital Management, LP | ١٩٬٣٣٠ | ١٩٬٣٣٠ | ٣٠/٦/٢٠٢٤ |
٠٫٠٣٨١٤ % | State of Wisconsin Investment Board | ١٩٬١٠٥ | -٩٩٣ | ٣٠/٦/٢٠٢٤ |
٠٫٠٣٧٥٣ % | SunAmerica Asset Management, LLC | ١٨٬٧٩٧ | ٥٣٣ | ٣١/٣/٢٠٢٤ |
٠٫٠٣٥٤٦ % | Edgestream Partners, L.P. | ١٧٬٧٦٠ | ١٧٬٧٦٠ | ٣٠/٦/٢٠٢٤ |
٠٫٠٣٥٠٣ % | DWS Investments UK Limited | ١٧٬٥٤٧ | -١٬٩٢٢ | ٣٠/٦/٢٠٢٤ |
٠٫٠٣٤٩٥ % | Wells Fargo Bank, N.A. | ١٧٬٥٠٤ | ٥٬٨٣٧ | ٣٠/٦/٢٠٢٤ |
٠٫٠٣٤٢٧ % | Kentucky Teachers' Retirement System | ١٧٬١٦٧ | 0 | ٣٠/٦/٢٠٢٤ |
٠٫٠٣٤١٨ % | Citi Investment Research (US) | ١٧٬١٢٢ | -١٧٣٬٢٢٣ | ٣٠/٦/٢٠٢٤ |
٠٫٠٣٣٨٩ % | JPMorgan Private Bank (United States) | ١٦٬٩٧٦ | ٢٬١٣٧ | ٣٠/٦/٢٠٢٤ |
٠٫٠٣٢٩٤ % | Guggenheim Investments | ١٦٬٥٠٢ | -٧٬٢٩١ | ٣١/٨/٢٠٢٤ |
٠٫٠٣٢٦٥ % | UBS Asset Management (Switzerland) | ١٦٬٣٥٤ | ٤٬٤٠٠ | ٣٠/٦/٢٠٢٤ |