٩٫٠٩٩١٢ % | The Vanguard Group, Inc. | ٢٥٬٤١٨٬٣٨٨ | ٩٧٩٬٨٥٧ | ٣١/١٢/٢٠٢٣ |
٨٫٥٠٢٠٩ % | RA Capital Management, LP | ٢٣٬٧٥٠٬٦٠١ | ١٠٬٤٢٨٬٣١٣ | ٣١/١٢/٢٠٢٣ |
٦٫٦٧٥٠٢ % | BlackRock Institutional Trust Company, N.A. | ١٨٬٦٤٦٬٦٧٩ | ١٬٧٩٣٬٧٨٦ | ٣١/١٢/٢٠٢٣ |
٥٫٨٧٩٣٣ % | Redmile Group, LLC | ١٦٬٤٢٣٬٩٢٢ | -١٬٠٧٩٬٤٩٥ | ٣١/١٢/٢٠٢٣ |
٣٫٩٥٣٤٦ % | Janus Henderson Investors | ١١٬٠٤٣٬٩٨٦ | -٦٬٦٤٠٬٨٣٠ | ٣١/١٢/٢٠٢٣ |
٢٫٨٩٠٨٨ % | State Street Global Advisors (US) | ٨٬٠٧٥٬٦٧١ | -١٬٤٧٦٬١٨١ | ٣١/١٢/٢٠٢٣ |
٢٫١٢٢٦٤ % | Fairmount Funds Management LLC | ٥٬٩٢٩٬٥٩٢ | 0 | ٣١/١٢/٢٠٢٣ |
٢٫٠٢٧٠٣ % | Pentwater Capital Management LP | ٥٬٦٦٢٬٥٠٠ | ٥٬٦٦٢٬٥٠٠ | ٣١/١٢/٢٠٢٣ |
١٫٩٨٢٩٤ % | Norges Bank Investment Management (NBIM) | ٥٬٥٣٩٬٣٣٤ | ٥٬٤٢٤٬٤٣٤ | ٣١/١٢/٢٠٢٣ |
١٫٩٢٦٩٣ % | Geode Capital Management, L.L.C. | ٥٬٣٨٢٬٨٧٥ | ٤٨٢٬٩٠٠ | ٣١/١٢/٢٠٢٣ |
١٫٩١٨٧٤ % | Fidelity Investments Canada ULC | ٥٬٣٦٠٬٠٠٠ | ٥٬٣٦٠٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
١٫٦١٩٠٤ % | D. E. Shaw & Co., L.P. | ٤٬٥٢٢٬٧٩٧ | -٢٬٤٧٢٬٤٤٢ | ٣١/١٢/٢٠٢٣ |
١٫٦٠١٥٣ % | Millennium Management LLC | ٤٬٤٧٣٬٨٦٨ | ٢٬٨٦٨٬١٥٤ | ٣١/١٢/٢٠٢٣ |
١٫١٥٣١٢ % | Voloridge Investment Management, LLC | ٣٬٢٢١٬٢٣١ | ٧٠٨٬٩٨٠ | ٣١/١٢/٢٠٢٣ |
١٫٠٥٩٩٦ % | Boxer Capital, L.L.C. | ٢٬٩٦١٬٠٠٠ | 0 | ٣١/١٢/٢٠٢٣ |
١٫٠٥٠٠١ % | Emerald Advisers LLC | ٢٬٩٣٣٬١٩٠ | -٣٤٤٬١٧٩ | ٣١/١٢/٢٠٢٣ |
٠٫٨٩٢٥١ % | Maverick Capital, Ltd. | ٢٬٤٩٣٬٢١٧ | -٢٥٬٣١٠ | ٣١/١٢/٢٠٢٣ |
٠٫٨٢٨٢٣ % | TIG Advisors, L.L.C. | ٢٬٣١٣٬٦٧٠ | ٢٬٣١٣٬٦٧٠ | ٣١/١٢/٢٠٢٣ |
٠٫٧٩٠٩٦ % | Morgan Stanley & Co. LLC | ٢٬٢٠٩٬٥٣٦ | ٦٤٬٥٨٣ | ٣١/١٢/٢٠٢٣ |
٠٫٧٨٧٢٣ % | Tang Capital Management, LLC | ٢٬١٩٩٬١٣٧ | ٦٩٩٬١٣٧ | ٣١/١٢/٢٠٢٣ |
٠٫٧٦١٣٣ % | Medical Strategy GmbH | ٢٬١٢٦٬٧٦٣ | 0 | ٣٠/٩/٢٠٢٣ |
٠٫٧٤٢٠٨ % | Northern Trust Investments, Inc. | ٢٬٠٧٢٬٩٩٨ | ٦٢٬١٩٦ | ٣١/١٢/٢٠٢٣ |
٠٫٧٣٠٧٠ % | Nuveen LLC | ٢٬٠٤١٬٢١٤ | -٨٤٥٬٠٢٧ | ٣١/١٢/٢٠٢٣ |
٠٫٧٢٨٨٩ % | Kryger Capital Limited | ٢٬٠٣٦٬١٥٥ | ٢٬٠٣٦٬١٥٥ | ٣١/١٢/٢٠٢٣ |
٠٫٦٩٩٦٣ % | Wellington Management Company, LLP | ١٬٩٥٤٬٤١٣ | -١١٬٣٠٤٬٥٨٤ | ٣١/١٢/٢٠٢٣ |
٠٫٦٧٧٤٥ % | Charles Schwab Investment Management, Inc. | ١٬٨٩٢٬٤٤٦ | ٦١٬٨٧١ | ٣١/١٢/٢٠٢٣ |
٠٫٦٥٤٨١ % | Avidity Partners Management LP | ١٬٨٢٩٬٢١٥ | -٨٨٬٦٩٢ | ٣١/١٢/٢٠٢٣ |
٠٫٦٣٩٠٩ % | HOOPP Investment Management | ١٬٧٨٥٬٢٩٦ | ١٬٤٨٥٬٢٩٦ | ٣١/١٢/٢٠٢٣ |
٠٫٦٣٠٥٠ % | Alpine Associates Management Inc. | ١٬٧٦١٬٣٠٠ | ١٬٧٤٩٬٣٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٥٨٣٩٤ % | Renaissance Technologies LLC | ١٬٦٣١٬٢٤٠ | ٨٩٦٬٦٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٥٨٣٢٤ % | Magnetar Capital Partners LP | ١٬٦٢٩٬٢٨٥ | ١٬٦٢٩٬٢٨٥ | ٣١/١٢/٢٠٢٣ |
٠٫٥٥٣٧٥ % | Sofinnova Investments, Inc | ١٬٥٤٦٬٩٠٢ | -٤٩٨٬٣٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٥٣٩٧٦ % | AllianceBernstein L.P. | ١٬٥٠٧٬٨٠٩ | ١٬٢٠٧٬٢٩٥ | ٣١/١٢/٢٠٢٣ |
٠٫٥٣٩٣٢ % | AQR Capital Management, LLC | ١٬٥٠٦٬٦٠١ | ١٬٣٨٠٬٩٦٤ | ٣١/١٢/٢٠٢٣ |
٠٫٥٣٥٨٠ % | Balyasny Asset Management LP | ١٬٤٩٦٬٧٥٨ | ١٬٤٨٤٬٨٣٨ | ٣١/١٢/٢٠٢٣ |
٠٫٥٣٢٣٨ % | Morgan Stanley Investment Management Inc. (US) | ١٬٤٨٧٬٢١٠ | -٥٤٤٬٧٨٧ | ٣١/١٢/٢٠٢٣ |
٠٫٥٠٩٣٣ % | Gabelli Funds, LLC | ١٬٤٢٢٬٨٠٤ | ١٬٤٢٢٬٨٠٤ | ٣١/١٢/٢٠٢٣ |
٠٫٥٠٩٢٢ % | Kynam Capital Management LP | ١٬٤٢٢٬٥٠٣ | ١٬٤٢٢٬٥٠٣ | ٣١/١٢/٢٠٢٣ |
٠٫٥٠٢٨١ % | Affinity Asset Advisors LLC | ١٬٤٠٤٬٦٠٨ | ١٬٤٠٤٬٦٠٨ | ٣١/١٢/٢٠٢٣ |
٠٫٤٩٢٥٤ % | QVT Financial LP | ١٬٣٧٥٬٩٠٠ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫٤٨٨٦١ % | Westchester Capital Management, LLC | ١٬٣٦٤٬٩٢٧ | ١٬٣٦٤٬٩٢٧ | ٣١/١٢/٢٠٢٣ |
٠٫٤٥٢٩٦ % | J.P. Morgan Securities LLC | ١٬٢٦٥٬٣٤٧ | ٢٨٬٦١٧ | ٣١/١٢/٢٠٢٣ |
٠٫٤٤٥٠١ % | BlackRock Financial Management, Inc. | ١٬٢٤٣٬١٤٧ | -٢٥٩٬٩٨٠ | ٣١/١٢/٢٠٢٣ |
٠٫٤٢٤٩٢ % | Marshall Wace LLP | ١٬١٨٧٬٠٢٧ | ١٬١٨٧٬٠٢٧ | ٣١/١٢/٢٠٢٣ |
٠٫٤١٩٦٦ % | Artisan Partners Limited Partnership | ١٬١٧٢٬٣٢٣ | -٢٬٥٥٢٬٢٦٠ | ٣١/١٢/٢٠٢٣ |
٠٫٤٠٣٥٨ % | Principal Global Investors (Equity) | ١٬١٢٧٬٤٠٢ | ١٤٢٬٧٣٨ | ٣١/١٢/٢٠٢٣ |
٠٫٤٠١٨٦ % | Candriam Belgium S.A. | ١٬١٢٢٬٥٩٨ | ١٠ | ٣١/١٢/٢٠٢٣ |
٠٫٤٠١٨٥ % | Candriam Luxembourg S.A. | ١٬١٢٢٬٥٥٧ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫٣٦٢٢٠ % | Pinnacle Associates Ltd. | ١٬٠١١٬٧٩٢ | -٤٬٣٦٤ | ٣١/١٢/٢٠٢٣ |
٠٫٣٤٩٣٧ % | Pictet Asset Management Ltd. | ٩٧٥٬٩٦٢ | -٢٬٧٣٢٬١٧٧ | ٣١/١٢/٢٠٢٣ |
٠٫٣٤٧٩٢ % | Adage Capital Management, L.P. | ٩٧١٬٩٢٨ | ٧٧١٬٩٢٨ | ٣١/١٢/٢٠٢٣ |
٠٫٣٤٧٦٢ % | BlackRock Advisors (UK) Limited | ٩٧١٬٠٧٠ | ١٩٬٧٩٩ | ٣١/١/٢٠٢٤ |
٠٫٣٤٤٩٥ % | T. Rowe Price Associates, Inc. | ٩٦٣٬٦٢٠ | -٢٬٨١١٬٥٥٤ | ٣١/١٢/٢٠٢٣ |
٠٫٣٣٩١٨ % | Lombard Odier Asset Management (Europe) Ltd | ٩٤٧٬٤٩٧ | -٣٦٬١٩٩ | ٣٠/٩/٢٠٢٢ |
٠٫٣٢٣٢٢ % | BlackRock Asset Management Ireland Limited | ٩٠٢٬٩٢٦ | -١٦٬٧٨٤ | ٣١/١٢/٢٠٢٣ |
٠٫٣١٩٩٤ % | Water Island Capital, LLC | ٨٩٣٬٧٥٨ | ٣٠٤٬٨٩٣ | ٣١/١٢/٢٠٢٣ |
٠٫٣١٧٥٣ % | Two Sigma Investments, LP | ٨٨٧٬٠١٨ | -٢٬٠٣٥٬٧١٧ | ٣١/١٢/٢٠٢٣ |
٠٫٣١٣٢٣ % | Avoro Capital Advisors LLC | ٨٧٥٬٠٠٠ | ٨٧٥٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٣٠١٤١ % | Farallon Capital Management, L.L.C. | ٨٤٢٬٠٠٠ | ٨٤٢٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٢٩٩٣١ % | American Century Investment Management, Inc. | ٨٣٦٬١٣٤ | ١٣٧٬٠١٨ | ٣١/١٢/٢٠٢٣ |
٠٫٢٨٩٦٩ % | Goldman Sachs & Company, Inc. | ٨٠٩٬٢٥٤ | -٦٤٬٦٨٤ | ٣١/١٢/٢٠٢٣ |
٠٫٢٨٤٧٥ % | Citadel Advisors LLC | ٧٩٥٬٤٥٨ | -٤٩٢٬٠٨٤ | ٣١/١٢/٢٠٢٣ |
٠٫٢٧٣١٣ % | Eventide Asset Management, LLC | ٧٦٣٬٠٠٠ | -٥٣٧٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫٢٧١٨٣ % | Rock Springs Capital Management LP | ٧٥٩٬٣٦٥ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫٢٧٠٥٥ % | BofA Global Research (US) | ٧٥٥٬٧٧٤ | ٢٧٠٬٣٨٦ | ٣١/١٢/٢٠٢٣ |
٠٫٢٦٨٩٦ % | DWS Investments UK Limited | ٧٥١٬٣٢٦ | ٦٣٠٬٥٩٠ | ٣١/١٢/٢٠٢٣ |
٠٫٢٦٨١٠ % | Eversept Partners, LP | ٧٤٨٬٩٥٠ | ٧٤٨٬٩٥٠ | ٣١/١٢/٢٠٢٣ |
٠٫٢٦٣٤٨ % | Susquehanna International Group, LLP | ٧٣٦٬٠٣٤ | -٢٣٨٬٨٥٣ | ٣١/١٢/٢٠٢٣ |
٠٫٢٥٧٧١ % | AQR Arbitrage, LLC | ٧١٩٬٩١٩ | ٧١٩٬٩١٩ | ٣١/١٢/٢٠٢٣ |
٠٫٢٤٤٢٨ % | IndexIQ Advisors LLC | ٦٨٢٬٣٩٦ | ٦٨٢٬٣٩٦ | ٣١/١٢/٢٠٢٣ |
٠٫٢٣٩٦١ % | Voya Investment Management LLC | ٦٦٩٬٣٥١ | ١٥٤٬٢١٥ | ٣١/١٢/٢٠٢٣ |
٠٫٢٣٦٩٢ % | BlackRock Investment Management, LLC | ٦٦١٬٨٣٥ | -١٣٬٠٩٦ | ٣١/١٢/٢٠٢٣ |
٠٫٢٣٦٢٤ % | Decheng Capital LLC | ٦٥٩٬٩٢٨ | ٢٤٤٬٠٤٨ | ٣١/١٢/٢٠٢٣ |
٠٫٢٣٦٢٠ % | BNY Mellon Asset Management | ٦٥٩٬٨٣٣ | -٣٠٬٨٢٢ | ٣١/١٢/٢٠٢٣ |
٠٫٢٣٠٦٧ % | Sio Capital Management, LLC | ٦٤٤٬٣٦٦ | ٤١١٬٦١٥ | ٣١/١٢/٢٠٢٣ |
٠٫٢٢٩٣٨ % | Barclays Bank PLC | ٦٤٠٬٧٧٧ | ٣٠٢٬٢٥٣ | ٣١/١٢/٢٠٢٣ |
٠٫٢٢٧٠٨ % | Jane Street Capital, L.L.C. | ٦٣٤٬٣٥٣ | -٢٨٣٬٤١١ | ٣١/١٢/٢٠٢٣ |
٠٫٢١٤٠٩ % | Superstring Capital Management LP | ٥٩٨٬٠٧٢ | ٥٩٨٬٠٧٢ | ٣١/١٢/٢٠٢٣ |
٠٫٢١٣٦١ % | First Trust Capital Management L.P. | ٥٩٦٬٧٢٠ | ٥٩٦٬٧٢٠ | ٣١/١٢/٢٠٢٣ |
٠٫٢١٠١٣ % | CPP Investment Board | ٥٨٦٬٩٩٠ | ٥٨٦٬٩٩٠ | ٣١/١٢/٢٠٢٣ |
٠٫٢٠٢٨٠ % | Baillie Gifford & Co. | ٥٦٦٬٥٢٩ | 0 | ٣١/١٠/٢٠٢٣ |
٠٫١٩٠٢٠ % | Melqart Asset Management (UK) Limited | ٥٣١٬٣٢٤ | ٥٣١٬٣٢٤ | ٣١/١٢/٢٠٢٣ |
٠٫١٨٦٠٧ % | HSBC Global Asset Management (UK) Limited | ٥١٩٬٧٧٩ | ٥١٩٬٧٧٩ | ٣١/١٢/٢٠٢٣ |
٠٫١٨٤٤٥ % | Invesco Capital Management LLC | ٥١٥٬٢٧٥ | ١٧٤٬٦١٤ | ٣١/١٢/٢٠٢٣ |
٠٫١٧٨٩٩ % | Picton Mahoney Asset Management | ٥٠٠٬٠٠٠ | ٥٠٠٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫١٧٨٩٩ % | CM Management, LLC | ٥٠٠٬٠٠٠ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫١٧٢٩٠ % | JPMorgan Private Bank (United States) | ٤٨٢٬٩٩٤ | -٢٠٬١٧٤ | ٣١/١٢/٢٠٢٣ |
٠٫١٧٢١١ % | Schweizerische Nationalbank | ٤٨٠٬٨٠٠ | 0 | ٣١/١٢/٢٠٢٣ |
٠٫١٦٦٨٨ % | Carlson Capital, L.P. | ٤٦٦٬١٨٨ | ٤٦٦٬١٨٨ | ٣١/١٢/٢٠٢٣ |
٠٫١٦٤٦٧ % | Slotnik Capital, LLC | ٤٦٠٬٠٠٠ | ٤٦٠٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫١٦٢٦٠ % | Dimensional Fund Advisors, L.P. | ٤٥٤٬٢١٣ | -٧٢٦٬٥٣١ | ٣١/١٢/٢٠٢٣ |
٠٫١٦٢٢٢ % | Fidelity Management & Research Company LLC | ٤٥٣٬١٦٨ | -٥٬٣٢٦٬٧٧٥ | ٣١/١٢/٢٠٢٣ |
٠٫١٤٩٣٧ % | Credit Suisse Funds AG | ٤١٧٬٢٧٧ | ١٢٨٬١٦٦ | ٣١/١٢/٢٠٢٣ |
٠٫١٤٨٥٦ % | Segantii Capital Management Limited | ٤١٥٬٠٠٠ | ٤١٥٬٠٠٠ | ٣١/١٢/٢٠٢٣ |
٠٫١٤٦٦٥ % | PanAgora Asset Management Inc. | ٤٠٩٬٦٥٨ | -٦٨٨٬٧٥٩ | ٣١/١٢/٢٠٢٣ |
٠٫١٤٣١٩ % | Woodline Partners LP | ٤٠٠٬٠٠٠ | -٢٬٠٣٣٬١٦١ | ٣١/١٢/٢٠٢٣ |
٠٫١٣٨٩٣ % | GLG LLC | ٣٨٨٬١٠٣ | ٣٧٤٬٠٠٥ | ٣١/١٢/٢٠٢٣ |
٠٫١٣٦٩٦ % | Mellon Investments Corporation | ٣٨٢٬٥٩٤ | -٤٨٢٬١٤٠ | ٣١/١٢/٢٠٢٣ |
٠٫١٣٣٢٨ % | Pictet Asset Management (Japan) Ltd. | ٣٧٢٬٣١٠ | ٣٧٢٬٣١٠ | ٣١/١٠/٢٠٢٣ |
٠٫١٣٢٤٧ % | Invesco Advisers, Inc. | ٣٧٠٬٠٤٨ | -٣٧٥٬٤٥٩ | ٣١/١٢/٢٠٢٣ |