15.30104 % | Antecip Capital, L.L.C. | 7,344,500 | 0 | 15/4/2567 |
9.65486 % | RTW Investments L.P. | 4,634,331 | 141,652 | 30/6/2567 |
7.78180 % | The Vanguard Group, Inc. | 3,735,263 | 1,724 | 30/6/2567 |
5.94936 % | BlackRock Institutional Trust Company, N.A. | 2,855,693 | 98,721 | 30/6/2567 |
4.91683 % | Fairmount Funds Management LLC | 2,360,077 | 0 | 30/6/2567 |
3.85997 % | Deep Track Capital LP | 1,852,784 | 548,063 | 30/6/2567 |
2.23592 % | Macquarie Investment Management | 1,073,242 | 372,832 | 30/6/2567 |
2.08333 % | RA Capital Management, LP | 1,000,000 | 0 | 30/6/2567 |
1.98958 % | BVF Partners L.P. | 955,000 | 955,000 | 30/6/2567 |
1.95565 % | Eventide Asset Management, LLC | 938,714 | 592,002 | 30/6/2567 |
1.95521 % | State Street Global Advisors (US) | 938,503 | -213 | 30/6/2567 |
1.84353 % | Geode Capital Management, L.L.C. | 884,895 | 39,488 | 30/6/2567 |
1.63869 % | BofA Global Research (US) | 786,573 | 669,746 | 30/6/2567 |
1.56924 % | Citadel Advisors LLC | 753,237 | -390,407 | 30/6/2567 |
1.54352 % | Alethea Capital Management, LLC | 740,888 | 97 | 30/6/2567 |
1.54129 % | Millennium Management LLC | 739,819 | -1,699 | 30/6/2567 |
1.53046 % | Wellington Management Company, LLP | 734,620 | 57,974 | 30/6/2567 |
1.52083 % | Adage Capital Management, L.P. | 730,000 | 215,000 | 30/6/2567 |
1.14389 % | Hood River Capital Management LLC | 549,066 | 28,316 | 30/6/2567 |
1.07611 % | Bellevue Asset Management AG | 516,533 | -168,943 | 30/6/2567 |
1.06127 % | Invesco Advisers, Inc. | 509,411 | 322,829 | 30/6/2567 |
1.03063 % | Fidelity Management & Research Company LLC | 494,703 | 31,361 | 30/6/2567 |
0.99801 % | Point72 Asset Management, L.P. | 479,044 | 100,180 | 30/6/2567 |
0.97381 % | PFM Health Sciences, LP | 467,427 | 0 | 30/6/2567 |
0.95648 % | Perceptive Advisors LLC | 459,111 | -646,230 | 30/6/2567 |
0.87178 % | Coleman (Mark H) | 418,456 | -10,497 | 29/5/2567 |
0.84882 % | Fidelity Institutional Asset Management | 407,433 | 42,225 | 30/6/2567 |
0.84212 % | Norges Bank Investment Management (NBIM) | 404,217 | 209,094 | 30/6/2567 |
0.83333 % | Boxer Capital, L.L.C. | 400,000 | 0 | 30/6/2567 |
0.83333 % | Cormorant Asset Management, LP | 400,000 | 400,000 | 30/6/2567 |
0.78333 % | Avidity Partners Management LP | 376,000 | -55,000 | 30/6/2567 |
0.73575 % | Goldman Sachs & Company, Inc. | 353,158 | 182,848 | 30/6/2567 |
0.70260 % | First Turn Management, LLC | 337,246 | -4,927 | 30/6/2567 |
0.66252 % | Woodline Partners LP | 318,011 | -42,117 | 30/6/2567 |
0.64625 % | Sofinnova Investments, Inc | 310,198 | 310,198 | 30/6/2567 |
0.64545 % | Charles Schwab Investment Management, Inc. | 309,818 | 8,744 | 30/6/2567 |
0.63857 % | Tri Locum Partners LP | 306,513 | 203,802 | 30/6/2567 |
0.62500 % | Vestal Point Capital, LP | 300,000 | 300,000 | 30/6/2567 |
0.61228 % | Northern Trust Investments, Inc. | 293,894 | -11,187 | 30/6/2567 |
0.60578 % | Checkpoint Capital L.P. | 290,772 | 158,335 | 30/6/2567 |
0.56060 % | Loomis, Sayles & Company, L.P. | 269,089 | -10,702 | 30/6/2567 |
0.42245 % | Morgan Stanley Smith Barney LLC | 202,778 | 20,734 | 30/6/2567 |
0.35159 % | AllianceBernstein L.P. | 168,762 | 88,608 | 30/6/2567 |
0.35090 % | Jane Street Capital, L.L.C. | 168,434 | -30,645 | 30/6/2567 |
0.34931 % | Jeffs (Roger A) | 167,668 | 0 | 15/4/2567 |
0.33118 % | BlackRock Financial Management, Inc. | 158,966 | 1,675 | 30/6/2567 |
0.31626 % | JP Morgan Asset Management | 151,806 | -6,409 | 30/6/2567 |
0.31250 % | Ghost Tree Capital, LLC | 150,000 | -60,000 | 30/6/2567 |
0.27735 % | U.S. Bancorp Asset Management, Inc. | 133,126 | 421 | 30/9/2567 |
0.27565 % | MPM BioImpact LLC | 132,312 | 18,185 | 30/6/2567 |
0.27186 % | BlackRock Advisors (UK) Limited | 130,494 | 119 | 30/9/2567 |
0.26583 % | Rhenman & Partners Asset Management AB | 127,600 | -16,000 | 30/6/2567 |
0.26417 % | Iridian Asset Management LLC | 126,803 | -102 | 30/9/2567 |
0.26198 % | BlackRock Asset Management Ireland Limited | 125,752 | -13,146 | 30/6/2567 |
0.23614 % | WCM Investment Management | 113,345 | 1,755 | 30/6/2567 |
0.22243 % | ClearBridge Investments, LLC | 106,767 | 17,397 | 30/6/2567 |
0.21930 % | Putnam Investment Management, L.L.C. | 105,266 | 941 | 30/6/2567 |
0.21087 % | HSBC Private Bank (Suisse) S.A. | 101,219 | 101,219 | 31/8/2567 |
0.20991 % | Nuveen LLC | 100,757 | -143,532 | 30/6/2567 |
0.20551 % | Eagle Asset Management, Inc. | 98,645 | -127,870 | 30/6/2567 |
0.20006 % | Frontier Capital Management Company, LLC | 96,027 | -9,317 | 30/6/2567 |
0.19982 % | BNY Mellon Asset Management | 95,913 | 5,278 | 30/6/2567 |
0.19433 % | BlackRock Investment Management, LLC | 93,278 | 6,938 | 30/6/2567 |
0.18524 % | Voya Investment Management LLC | 88,915 | 69,628 | 30/6/2567 |
0.18302 % | Artia Global Partners LP | 87,848 | 0 | 30/6/2567 |
0.17613 % | Medical Strategy GmbH | 84,541 | -6,849 | 30/6/2567 |
0.17102 % | Cannell & Spears LLC | 82,092 | -638 | 30/6/2567 |
0.17016 % | Wells Fargo Bank, N.A. | 81,677 | 70,990 | 30/6/2567 |
0.16667 % | Affinity Asset Advisors LLC | 80,000 | -59,758 | 30/6/2567 |
0.16388 % | Morgan Stanley & Co. LLC | 78,662 | -444,365 | 30/6/2567 |
0.16060 % | Pictet Asset Management (Japan) Ltd. | 77,087 | 77,087 | 30/4/2567 |
0.15838 % | Walleye Capital LLC | 76,023 | -21,097 | 30/6/2567 |
0.15576 % | Neuberger Berman, LLC | 74,767 | -16,889 | 30/6/2567 |
0.15486 % | Privium Fund Management BV | 74,332 | -7,700 | 30/6/2567 |
0.15286 % | Managed Account Advisors LLC | 73,375 | 26,992 | 30/6/2567 |
0.14985 % | Peregrine Capital Management, LLC | 71,929 | -15,444 | 30/9/2567 |
0.14651 % | Lindbrook Capital, LLC | 70,326 | -13,442 | 30/6/2567 |
0.14585 % | SpiderRock Advisors LLC | 70,008 | -11 | 30/6/2567 |
0.14491 % | Scout Investments, Inc. | 69,558 | 35,527 | 30/6/2567 |
0.13226 % | Mellon Investments Corporation | 63,486 | 10,767 | 30/6/2567 |
0.12969 % | DWS Investment Management Americas, Inc. | 62,253 | -884 | 30/6/2567 |
0.12957 % | HighVista Strategies LLC | 62,192 | 13,665 | 30/6/2567 |
0.12634 % | Moody Aldrich Partners, LLC | 60,644 | -1,107 | 30/9/2567 |
0.12604 % | Schweizerische Nationalbank | 60,500 | 0 | 30/6/2567 |
0.12323 % | William Blair & Company, L.L.C. (Research) | 59,151 | -4,396 | 30/6/2567 |
0.12273 % | Schonfeld Strategic Advisors LLC | 58,909 | -1,273 | 30/6/2567 |
0.12146 % | International Biotechnology Trust PLC | 58,300 | 0 | 30/9/2566 |
0.12146 % | Schroder Investment Management Ltd. (SIM) | 58,300 | 0 | 30/6/2567 |
0.12114 % | Hennion & Walsh Asset Management, Inc. | 58,148 | -6,537 | 30/9/2567 |
0.11444 % | Rhumbline Advisers Ltd. Partnership | 54,931 | 2,674 | 30/6/2567 |
0.10417 % | Altium Capital Management LP | 50,000 | -88,000 | 30/6/2567 |
0.10353 % | Baldwin Brothers, LLC. | 49,695 | 0 | 30/9/2567 |
0.10208 % | Atika Capital Management LLC | 49,000 | -19,000 | 30/6/2567 |
0.10035 % | Goldman Sachs Asset Management, L.P. | 48,169 | -73,133 | 30/6/2567 |
0.09612 % | INVESCO Asset Management Limited | 46,137 | -10,831 | 30/6/2567 |
0.08980 % | Pizzie (Nick) | 43,104 | 827 | 15/4/2567 |
0.08902 % | Columbia Threadneedle Investments (US) | 42,730 | 33,400 | 30/6/2567 |
0.08481 % | WMS Partners LLC | 40,711 | 0 | 30/6/2567 |
0.08463 % | SEI Investments Management Corporation | 40,624 | 4,970 | 30/6/2567 |
0.08333 % | Wells Fargo Securities, LLC | 40,000 | 40,000 | 30/6/2567 |