15.00068 % | Fidelity Management & Research Company LLC | 7,513,840 | 8,426 | 30/6/2567 |
9.94798 % | EcoR1 Capital, LLC | 4,982,945 | 1,968,193 | 30/6/2567 |
6.04139 % | Springer Timothy A | 3,026,133 | -4,608,052 | 16/8/2567 |
5.87616 % | BlackRock Institutional Trust Company, N.A. | 2,943,371 | 175,446 | 30/6/2567 |
5.04292 % | Invus Public Equities Advisors, LLC | 2,525,998 | 312,810 | 30/6/2567 |
4.41291 % | The Vanguard Group, Inc. | 2,210,429 | -45,246 | 30/6/2567 |
4.29650 % | T. Rowe Price Associates, Inc. | 2,152,117 | -318,042 | 30/6/2567 |
3.97415 % | Polaris Venture Partners | 1,990,651 | 0 | 1/4/2567 |
3.56000 % | Woodline Partners LP | 1,783,202 | 1,683,202 | 30/6/2567 |
3.27033 % | State Street Global Advisors (US) | 1,638,108 | -1,027,402 | 30/6/2567 |
2.91735 % | Point72 Asset Management, L.P. | 1,461,302 | -3,225,798 | 30/6/2567 |
2.03217 % | Pictet Asset Management Ltd. | 1,017,912 | -168,996 | 30/6/2567 |
1.98642 % | Federated Hermes Global Investment Management Corp. | 995,000 | 0 | 30/6/2567 |
1.93649 % | Geode Capital Management, L.L.C. | 969,986 | 74,786 | 30/6/2567 |
1.22674 % | Tipirneni (Praveen P) | 614,474 | -42,460 | 16/8/2567 |
1.22280 % | OrbiMed Advisors, LLC | 612,500 | 54,000 | 30/6/2567 |
1.15396 % | Two Sigma Investments, LP | 578,020 | -63,831 | 30/6/2567 |
1.06734 % | Goldman Sachs & Company, Inc. | 534,630 | 103,925 | 30/6/2567 |
0.97086 % | SilverArc Capital Management, LLC | 486,306 | 2,334 | 30/6/2567 |
0.73744 % | MPM BioImpact LLC | 369,384 | 44,051 | 30/6/2567 |
0.65451 % | Charles Schwab Investment Management, Inc. | 327,844 | 1,147 | 30/6/2567 |
0.64564 % | BlackRock Financial Management, Inc. | 323,403 | 27,905 | 30/6/2567 |
0.62802 % | Northern Trust Investments, Inc. | 314,575 | -646 | 30/6/2567 |
0.50025 % | Affinity Asset Advisors LLC | 250,573 | 25,573 | 30/6/2567 |
0.48898 % | Wellington Management Company, LLP | 244,931 | -5,569,515 | 31/7/2567 |
0.46266 % | Dafna Capital Management, LLC | 231,748 | 0 | 30/6/2567 |
0.42796 % | Fiduciary Trust Company | 214,366 | 0 | 30/6/2567 |
0.42754 % | Candriam Belgium S.A. | 214,154 | -35,779 | 30/6/2567 |
0.41570 % | Dimensional Fund Advisors, L.P. | 208,225 | -12,937 | 30/6/2567 |
0.32339 % | Citadel Advisors LLC | 161,988 | -704,910 | 30/6/2567 |
0.32121 % | Voloridge Investment Management, LLC | 160,896 | 160,896 | 30/6/2567 |
0.31912 % | Omega Fund Management, LLC | 159,846 | 0 | 30/6/2567 |
0.30509 % | D. E. Shaw & Co., L.P. | 152,819 | -61,637 | 30/6/2567 |
0.30057 % | AllianceBernstein L.P. | 150,558 | 38,776 | 30/6/2567 |
0.29207 % | Nomura Asset Management Co., Ltd. | 146,300 | 146,300 | 30/11/2566 |
0.26968 % | Morgan Stanley & Co. LLC | 135,082 | -67,468 | 30/6/2567 |
0.26208 % | Jane Street Capital, L.L.C. | 131,276 | 85,314 | 30/6/2567 |
0.25893 % | Nuveen LLC | 129,698 | 3,897 | 30/6/2567 |
0.25746 % | Medical Strategy GmbH | 128,962 | -313,051 | 31/12/2566 |
0.23516 % | BlackRock Investment Management, LLC | 117,794 | 24,237 | 30/6/2567 |
0.22736 % | Ensign Peak Advisors, Inc. | 113,883 | -27,340 | 30/6/2567 |
0.22380 % | TD Asset Management Inc. | 112,100 | -13,800 | 30/6/2567 |
0.19753 % | Goldman Sachs Asset Management, L.P. | 98,943 | -14,297 | 30/6/2567 |
0.19217 % | BNY Mellon Asset Management | 96,256 | 5,819 | 30/6/2567 |
0.17721 % | Barclays Bank PLC | 88,766 | 44,039 | 30/6/2567 |
0.17162 % | Manulife Investment Management (North America) Limited | 85,966 | 4,021 | 30/6/2567 |
0.17156 % | Susquehanna International Group, LLP | 85,932 | 16,033 | 30/6/2567 |
0.16814 % | BofA Global Research (US) | 84,223 | -30,339 | 30/6/2567 |
0.15981 % | Allianz Global Investors GmbH | 80,049 | -13,621 | 30/6/2567 |
0.15879 % | Jump Financial, LLC | 79,539 | 67,387 | 30/6/2567 |
0.15525 % | Capital Fund Management S.A. | 77,767 | 58,100 | 30/6/2567 |
0.14885 % | Rafferty Asset Management LLC | 74,557 | -146,237 | 30/6/2567 |
0.14574 % | HOOPP Investment Management | 73,000 | 73,000 | 30/6/2567 |
0.13302 % | Atom Investors LP | 66,628 | -20,002 | 30/6/2567 |
0.13052 % | Rhumbline Advisers Ltd. Partnership | 65,379 | 13,677 | 30/6/2567 |
0.12530 % | BlackRock Asset Management Ireland Limited | 62,765 | 3,150 | 30/6/2567 |
0.11759 % | Schweizerische Nationalbank | 58,900 | 0 | 30/6/2567 |
0.11572 % | Connor, Clark & Lunn Investment Management Ltd. | 57,965 | -46,665 | 30/6/2567 |
0.10994 % | T. Rowe Price International Ltd | 55,070 | 1,643 | 30/6/2567 |
0.10773 % | Mellon Investments Corporation | 53,963 | 21,651 | 30/6/2567 |
0.10730 % | PGIM Quantitative Solutions LLC | 53,747 | -26,180 | 30/6/2567 |
0.09515 % | Saturn V Capital Management LP | 47,660 | -37,972 | 30/6/2567 |
0.08628 % | BlackRock Investment Management (UK) Ltd. | 43,220 | 9,516 | 30/6/2567 |
0.08277 % | UBS Financial Services, Inc. | 41,460 | -107,534 | 30/6/2567 |
0.07797 % | Alps Advisors, Inc. | 39,054 | 3,762 | 30/6/2567 |
0.06813 % | Millennium Management LLC | 34,125 | 34,125 | 30/6/2567 |
0.06610 % | Algert Global LLC | 33,108 | 16,531 | 30/6/2567 |
0.06339 % | Wellington Management Singapore Pte. Ltd. | 31,751 | 31,751 | 31/3/2567 |
0.06339 % | Wellington Management Japan Pte Ltd | 31,751 | -13,447 | 30/6/2566 |
0.05999 % | California State Teachers Retirement System | 30,048 | -631 | 30/6/2567 |
0.05968 % | Carmignac Gestion | 29,892 | 29,892 | 31/7/2567 |
0.05832 % | Legal & General Investment Management Ltd. | 29,214 | -185 | 30/6/2567 |
0.05694 % | Victory Capital Management Inc. | 28,520 | -580 | 30/6/2567 |
0.05660 % | UBS Asset Management (Americas), Inc. | 28,350 | 28,350 | 31/3/2566 |
0.05364 % | First Trust Advisors L.P. | 26,867 | 26,867 | 30/6/2567 |
0.05285 % | PDT Partners, LLC | 26,474 | -34,663 | 30/6/2567 |
0.04991 % | Tudor Investment Corporation | 25,002 | -882 | 30/6/2567 |
0.04951 % | T. Rowe Price Japan, Inc. | 24,799 | 15,500 | 30/4/2567 |
0.04877 % | Aperio Group, LLC | 24,427 | 629 | 30/6/2567 |
0.04873 % | Northern Trust Global Investments | 24,409 | 1,106 | 30/6/2567 |
0.04855 % | UBS Fund Management (Switzerland) AG | 24,319 | -7,904 | 30/6/2567 |
0.04789 % | Mirae Asset Global Investments (USA) LLC | 23,986 | 4,698 | 30/6/2567 |
0.04736 % | Squarepoint Capital LLP | 23,723 | 23,723 | 30/6/2567 |
0.04618 % | American Century Investment Management, Inc. | 23,134 | 16,606 | 30/6/2567 |
0.04607 % | MetLife Investment Management, LLC | 23,077 | 3,665 | 30/6/2567 |
0.04425 % | DeVaul (William David) | 22,167 | 0 | 8/7/2567 |
0.04284 % | Y-Intercept (Hong Kong) Ltd | 21,459 | 21,459 | 30/6/2567 |
0.04278 % | Corebridge Financial Inc | 21,431 | 21,431 | 30/6/2567 |
0.04033 % | Healthinvest Partners AB | 20,199 | 5,247 | 30/6/2567 |
0.03859 % | ExodusPoint Capital Management, LP | 19,330 | 19,330 | 30/6/2567 |
0.03814 % | State of Wisconsin Investment Board | 19,105 | -993 | 30/6/2567 |
0.03753 % | SunAmerica Asset Management, LLC | 18,797 | 533 | 31/3/2567 |
0.03546 % | Edgestream Partners, L.P. | 17,760 | 17,760 | 30/6/2567 |
0.03503 % | DWS Investments UK Limited | 17,547 | -1,922 | 30/6/2567 |
0.03495 % | Wells Fargo Bank, N.A. | 17,504 | 5,837 | 30/6/2567 |
0.03427 % | Kentucky Teachers' Retirement System | 17,167 | 0 | 30/6/2567 |
0.03418 % | Citi Investment Research (US) | 17,122 | -173,223 | 30/6/2567 |
0.03389 % | JPMorgan Private Bank (United States) | 16,976 | 2,137 | 30/6/2567 |
0.03294 % | Guggenheim Investments | 16,502 | -7,291 | 31/8/2567 |
0.03265 % | UBS Asset Management (Switzerland) | 16,354 | 4,400 | 30/6/2567 |