49.38416 % | Viking Global Investors LP | 7,150,826 | 0 | 31/12/2566 |
32.62574 % | RA Capital Management, LP | 4,724,207 | 0 | 31/12/2566 |
29.39298 % | Perceptive Advisors LLC | 4,256,104 | 0 | 31/12/2566 |
22.61258 % | Kayyem (Jon Faiz) | 3,274,301 | 0 | 21/2/2567 |
21.03352 % | Lappe Mark | 3,045,654 | 0 | 21/2/2567 |
17.06906 % | BlackRock Institutional Trust Company, N.A. | 2,471,600 | 179,080 | 31/12/2566 |
16.26763 % | Eckelman (Brendan P) | 2,355,553 | 0 | 21/2/2567 |
16.01227 % | Woodline Partners LP | 2,318,576 | 793,661 | 31/12/2566 |
12.91364 % | The Vanguard Group, Inc. | 1,869,895 | 84,512 | 31/12/2566 |
12.08831 % | TCG Crossover Management, LLC | 1,750,387 | 0 | 31/12/2566 |
11.29645 % | State Street Global Advisors (US) | 1,635,726 | 18,955 | 31/12/2566 |
10.56630 % | Vestal Point Capital, LP | 1,530,000 | 1,530,000 | 31/12/2566 |
10.15131 % | Fidelity Management & Research Company LLC | 1,469,909 | -47,686 | 31/12/2566 |
7.47393 % | Loomis, Sayles & Company, L.P. | 1,082,225 | -34,259 | 31/12/2566 |
6.60829 % | ArrowMark Colorado Holdings, LLC | 956,881 | -9,115 | 31/12/2566 |
5.33810 % | Sofinnova Investments, Inc | 772,957 | 29,663 | 31/12/2566 |
4.91961 % | Capital Research Global Investors | 712,360 | -509,361 | 31/12/2566 |
4.78577 % | BofA Global Research (US) | 692,980 | 577,231 | 31/12/2566 |
4.74696 % | Geode Capital Management, L.L.C. | 687,360 | 41,201 | 31/12/2566 |
4.13161 % | Forsyth Douglas | 598,257 | 0 | 21/2/2567 |
3.71522 % | PFM Health Sciences, LP | 537,964 | 249,347 | 31/12/2566 |
3.00725 % | Russell Investments Trust Company | 435,450 | -23,606 | 31/12/2566 |
1.95010 % | Northern Trust Investments, Inc. | 282,375 | 11,557 | 31/12/2566 |
1.83503 % | Morgan Stanley & Co. LLC | 265,712 | -80,617 | 31/12/2566 |
1.80289 % | Millennium Management LLC | 261,058 | 228,730 | 31/12/2566 |
1.75993 % | Citadel Advisors LLC | 254,838 | 12,028 | 31/12/2566 |
1.58747 % | Charles Schwab Investment Management, Inc. | 229,866 | 17,762 | 31/12/2566 |
1.56458 % | Sphera Funds Management Ltd. | 226,551 | -29,820 | 31/12/2566 |
1.51036 % | Two Sigma Investments, LP | 218,700 | -299,170 | 31/12/2566 |
1.15858 % | Platinum Asset Management | 167,763 | -61,273 | 31/12/2566 |
1.00413 % | Wellington Management Company, LLP | 145,398 | -29,501 | 31/12/2566 |
0.94149 % | Wetherby Asset Management LLC | 136,328 | 0 | 31/12/2566 |
0.93280 % | Candriam Belgium S.A. | 135,069 | -20,000 | 31/12/2566 |
0.91091 % | Hightower Advisors, LLC | 131,900 | 0 | 31/12/2566 |
0.90673 % | Schroder Investment Management Ltd. (SIM) | 131,295 | -106,148 | 31/12/2566 |
0.84472 % | Meridian Wealth Advisors, LLC | 122,315 | 0 | 31/12/2566 |
0.75913 % | Polen Capital Management, LLC | 109,922 | -50,737 | 29/2/2567 |
0.73339 % | Susquehanna International Group, LLP | 106,195 | 77,242 | 31/12/2566 |
0.71302 % | Rafferty Asset Management LLC | 103,246 | -12,582 | 31/12/2566 |
0.70289 % | Goldman Sachs & Company, Inc. | 101,778 | -10,302 | 31/12/2566 |
0.69923 % | abrdn Investments Limited | 101,249 | 80,950 | 31/3/2567 |
0.69061 % | Logos Global Management LLC | 100,000 | 100,000 | 31/12/2566 |
0.65608 % | Caption Management, LLC | 95,000 | 95,000 | 31/12/2566 |
0.62095 % | BNY Mellon Asset Management | 89,914 | 6 | 31/12/2566 |
0.62001 % | BlackRock Investment Management, LLC | 89,778 | -2,352 | 31/12/2566 |
0.61692 % | Schonfeld Strategic Advisors LLC | 89,330 | 89,330 | 31/12/2566 |
0.61371 % | Barclays Bank PLC | 88,865 | 25,688 | 31/12/2566 |
0.61115 % | BlackRock Financial Management, Inc. | 88,494 | -2,412 | 31/12/2566 |
0.57545 % | Nuveen LLC | 83,325 | -5,938 | 31/12/2566 |
0.55791 % | UBS Financial Services, Inc. | 80,785 | 42,782 | 31/12/2566 |
0.50523 % | Exome Asset Management LLC | 73,158 | 73,158 | 31/12/2566 |
0.49371 % | AllianceBernstein L.P. | 71,489 | -20,040 | 31/12/2566 |
0.38794 % | Ensign Peak Advisors, Inc. | 56,173 | 0 | 31/12/2566 |
0.37862 % | BlackRock Advisors (UK) Limited | 54,824 | 2,537 | 31/3/2567 |
0.35499 % | Goldman Sachs Asset Management, L.P. | 51,402 | 4,013 | 31/12/2566 |
0.33941 % | Rhumbline Advisers Ltd. Partnership | 49,147 | 322 | 31/12/2566 |
0.33459 % | Birchview Capital, LP | 48,448 | -22,000 | 31/12/2566 |
0.32062 % | HAP Trading, LLC | 46,426 | 46,426 | 31/12/2566 |
0.31176 % | BlackRock Asset Management Ireland Limited | 45,143 | 3,702 | 31/12/2566 |
0.30863 % | Citi Investment Research (US) | 44,690 | -4,554 | 31/12/2566 |
0.30438 % | Gyon Technologies Capital Management, LP | 44,074 | 44,074 | 31/12/2565 |
0.30356 % | State of Wisconsin Investment Board | 43,956 | -8,926 | 31/12/2566 |
0.28298 % | IndexIQ Advisors LLC | 40,976 | -1,568 | 31/3/2567 |
0.27969 % | Qube Research & Technologies Ltd | 40,499 | 40,499 | 31/12/2566 |
0.27032 % | Invesco Capital Management LLC | 39,143 | 31,795 | 31/12/2566 |
0.26727 % | Schweizerische Nationalbank | 38,700 | -18,900 | 31/12/2566 |
0.26206 % | Jane Street Capital, L.L.C. | 37,946 | -4,369 | 31/12/2566 |
0.24766 % | Simplex Trading, LLC | 35,861 | 35,225 | 31/12/2566 |
0.24171 % | Ghost Tree Capital, LLC | 35,000 | 0 | 31/12/2566 |
0.22864 % | Alps Advisors, Inc. | 33,107 | 33,107 | 31/12/2566 |
0.22304 % | Assenagon Asset Management S.A. | 32,296 | 2,344 | 29/2/2567 |
0.21176 % | Parametric Portfolio Associates LLC | 30,663 | -5,110 | 31/12/2566 |
0.21106 % | Hennion & Walsh Asset Management, Inc. | 30,561 | 744 | 31/3/2567 |
0.21046 % | Northern Trust Global Investments | 30,474 | -5,346 | 31/12/2566 |
0.19510 % | Alpine Associates Management Inc. | 28,251 | 12,959 | 31/3/2567 |
0.18232 % | Deka Vermögensmanagement GmbH | 26,400 | 0 | 31/12/2566 |
0.18232 % | Deka Investment GmbH | 26,400 | 0 | 31/12/2565 |
0.16989 % | Bellevue Asset Management AG | 24,600 | -24,200 | 31/12/2566 |
0.16700 % | Mellon Investments Corporation | 24,181 | 96 | 31/12/2566 |
0.16427 % | Wilmington Trust Investment Advisors, Inc. | 23,786 | -4,647 | 31/12/2566 |
0.16240 % | Campbell & Company, Inc. | 23,516 | 23,516 | 31/12/2566 |
0.15988 % | California State Teachers Retirement System | 23,150 | -7,554 | 31/12/2566 |
0.15689 % | JPMorgan Private Bank (United States) | 22,718 | 2,425 | 31/12/2566 |
0.15305 % | UBS Asset Management (Switzerland) | 22,161 | 0 | 31/12/2566 |
0.14153 % | Mirae Asset Global Investments (USA) LLC | 20,494 | 1,331 | 31/12/2566 |
0.13634 % | Credit Suisse Funds AG | 19,742 | -2,364 | 31/12/2566 |
0.13357 % | Alaethes Wealth LLC | 19,341 | 0 | 31/12/2566 |
0.13305 % | Legal & General Investment Management Ltd. | 19,265 | -2,896 | 31/12/2566 |
0.13249 % | JP Morgan Asset Management | 19,185 | -299,409 | 31/12/2566 |
0.12693 % | Tudor Investment Corporation | 18,379 | -3,331 | 31/12/2566 |
0.12565 % | MetLife Investment Management, LLC | 18,194 | 0 | 31/12/2566 |
0.11826 % | ProFund Advisors LLC | 17,124 | -2,622 | 31/12/2566 |
0.11789 % | SunAmerica Asset Management, LLC | 17,071 | -69 | 31/12/2566 |
0.11213 % | Prelude Capital Management, LLC | 16,236 | 3,015 | 31/12/2566 |
0.10535 % | Aperio Group, LLC | 15,255 | 3,062 | 31/12/2566 |
0.10359 % | Soleus Capital Management, L.P. | 15,000 | -534,183 | 31/12/2566 |
0.10332 % | DWS Investments UK Limited | 14,961 | -418 | 31/12/2566 |
0.10124 % | RS Crum INC | 14,659 | 0 | 31/12/2566 |
0.09985 % | LMR Partners LLP | 14,458 | 0 | 31/12/2566 |
0.09814 % | Wells Fargo Advisors | 14,211 | -550 | 31/12/2566 |