11,35408 % | Jennison Associates LLC | 5 546 467 | 376 232 | 2024-06-30 |
7,93902 % | T. Rowe Price Investment Management, Inc. | 3 878 210 | 1 407 717 | 2024-06-30 |
6,77555 % | BlackRock Institutional Trust Company, N.A. | 3 309 856 | 553 132 | 2024-06-30 |
6,21626 % | Adage Capital Management, L.P. | 3 036 645 | 0 | 2024-06-30 |
5,65177 % | Bain Capital Life Sciences Investors, LLC | 2 760 888 | 1 110 924 | 2024-08-12 |
5,16455 % | Fred Alger Management, LLC | 2 522 882 | −587 432 | 2024-06-30 |
4,83163 % | The Vanguard Group, Inc. | 2 360 250 | 89 835 | 2024-06-30 |
4,53767 % | Alkeon Capital Management LLC | 2 216 650 | 1 799 640 | 2024-06-30 |
3,20154 % | VR Adviser, LLC | 1 563 952 | 0 | 2024-06-30 |
2,76250 % | Nichtberger (Steven) | 1 349 483 | 0 | 2024-04-04 |
2,56602 % | Polar Capital LLP | 1 253 500 | 3 500 | 2024-06-30 |
2,49826 % | Sofinnova Investments, Inc | 1 220 400 | 790 654 | 2024-06-30 |
2,43650 % | BlackRock Financial Management, Inc. | 1 190 229 | 109 677 | 2024-06-30 |
2,41168 % | StemPoint Capital LP | 1 178 105 | 174 189 | 2024-06-30 |
2,25179 % | Commodore Capital LP | 1 100 000 | 0 | 2024-06-30 |
1,98684 % | Geode Capital Management, L.L.C. | 970 573 | 197 483 | 2024-06-30 |
1,83444 % | State Street Global Advisors (US) | 896 123 | −1 109 678 | 2024-09-30 |
1,42951 % | Millennium Management LLC | 698 317 | 238 950 | 2024-06-30 |
1,29829 % | Victory Capital Management Inc. | 634 217 | 262 594 | 2024-06-30 |
1,29214 % | JP Morgan Asset Management | 631 211 | 630 368 | 2024-06-30 |
1,19764 % | Perceptive Advisors LLC | 585 045 | −1 131 615 | 2024-06-30 |
1,14866 % | T. Rowe Price Associates, Inc. | 561 120 | −34 064 | 2024-06-30 |
1,00738 % | Lynx1 Capital Advisors LLC | 492 103 | −1 590 870 | 2024-06-30 |
0,95791 % | Two Sigma Investments, LP | 467 937 | 431 263 | 2024-06-30 |
0,95036 % | Deerfield Management Company, L.P. | 464 252 | −794 398 | 2024-06-30 |
0,90650 % | Redmile Group, LLC | 442 826 | 0 | 2024-06-30 |
0,87001 % | Integral Health Asset Management, LLC | 425 000 | 0 | 2024-06-30 |
0,82160 % | Oppenheimer Asset Management Inc. | 401 350 | 318 360 | 2024-06-30 |
0,76604 % | Goldman Sachs & Company, Inc. | 374 210 | −15 066 | 2024-06-30 |
0,75926 % | Ghost Tree Capital, LLC | 370 899 | −4 101 | 2024-06-30 |
0,67592 % | Marshall Wace LLP | 330 187 | 159 000 | 2024-06-30 |
0,67021 % | Artisan Partners Limited Partnership | 327 397 | −7 416 | 2024-06-30 |
0,65414 % | Citadel Advisors LLC | 319 546 | 317 305 | 2024-06-30 |
0,64561 % | Squarepoint Capital LLP | 315 379 | 272 948 | 2024-06-30 |
0,62409 % | UBS Asset Management (Americas), Inc. | 304 870 | 278 080 | 2024-06-30 |
0,62093 % | Qube Research & Technologies Ltd | 303 326 | −131 174 | 2024-06-30 |
0,61453 % | Exome Asset Management LLC | 300 200 | 300 200 | 2024-06-30 |
0,61372 % | PanAgora Asset Management Inc. | 299 801 | 299 801 | 2024-06-30 |
0,60720 % | Jane Street Capital, L.L.C. | 296 615 | 245 896 | 2024-06-30 |
0,58633 % | E Fund Management Co. Ltd. | 286 424 | 269 675 | 2024-06-30 |
0,58245 % | Northern Trust Investments, Inc. | 284 529 | 3 009 | 2024-06-30 |
0,58137 % | PGIM Securities Investment Trust Enterprise | 284 000 | −199 265 | 2024-06-30 |
0,55431 % | AXA Investment Managers UK Ltd. | 270 778 | 92 616 | 2024-06-30 |
0,53588 % | JPMorgan Asset Management U.K. Limited | 261 777 | −28 603 | 2024-06-30 |
0,49740 % | Woodline Partners LP | 242 981 | 318 | 2024-06-30 |
0,45019 % | Weatherbie Capital, LLC | 219 916 | 53 307 | 2024-08-31 |
0,39721 % | Schonfeld Strategic Advisors LLC | 194 037 | −123 483 | 2024-06-30 |
0,38886 % | Walleye Capital LLC | 189 957 | 189 957 | 2024-06-30 |
0,37285 % | Jump Financial, LLC | 182 135 | 182 135 | 2024-06-30 |
0,35955 % | Morgan Stanley Smith Barney LLC | 175 640 | 44 145 | 2024-06-30 |
0,34827 % | Westwood Management Corp. (Texas) | 170 129 | 87 901 | 2024-06-30 |
0,34617 % | BofA Global Research (US) | 169 105 | −20 875 | 2024-06-30 |
0,32753 % | Raiffeisen Kapitalanlage-Gesellschaft mbH | 160 000 | 0 | 2024-08-31 |
0,32510 % | Wellington Management Company, LLP | 158 809 | −849 450 | 2024-06-30 |
0,30731 % | Nuveen LLC | 150 123 | −46 104 | 2024-06-30 |
0,30359 % | BlackRock Investment Management, LLC | 148 305 | 40 490 | 2024-06-30 |
0,29303 % | Simon (Mark) | 143 144 | 0 | 2024-04-04 |
0,28638 % | Superstring Capital Management LP | 139 895 | −150 902 | 2024-06-30 |
0,27437 % | TD Asset Management Inc. | 134 030 | 7 000 | 2024-06-30 |
0,26264 % | MFS Investment Management | 128 298 | 0 | 2024-08-31 |
0,24223 % | Charles Schwab Investment Management, Inc. | 118 327 | 24 802 | 2024-06-30 |
0,23916 % | Morgan Stanley & Co. LLC | 116 832 | −617 325 | 2024-06-30 |
0,22518 % | Medical Strategy GmbH | 110 000 | −15 000 | 2024-06-30 |
0,22467 % | BNY Mellon Asset Management | 109 751 | 23 972 | 2024-06-30 |
0,21434 % | Crestline Investors, Inc. | 104 705 | 19 705 | 2024-06-30 |
0,21204 % | Rafferty Asset Management LLC | 103 582 | −250 842 | 2024-06-30 |
0,19488 % | Prelude Capital Management, LLC | 95 200 | 95 200 | 2024-06-30 |
0,18154 % | BlackRock Asset Management Ireland Limited | 88 683 | 12 090 | 2024-06-30 |
0,17768 % | TCG Crossover Management, LLC | 86 795 | 0 | 2024-06-30 |
0,15663 % | Voloridge Investment Management, LLC | 76 513 | −201 610 | 2024-06-30 |
0,14330 % | LifeSci Fund Management LLC | 70 000 | 5 000 | 2024-06-30 |
0,14037 % | UBS Financial Services, Inc. | 68 573 | −140 903 | 2024-06-30 |
0,13710 % | Susquehanna International Group, LLP | 66 973 | 2 874 | 2024-06-30 |
0,13613 % | Schweizerische Nationalbank | 66 500 | 7 300 | 2024-06-30 |
0,13230 % | AllianceBernstein L.P. | 64 630 | 33 320 | 2024-06-30 |
0,13167 % | Healthinvest Partners AB | 64 321 | −13 219 | 2024-06-30 |
0,12864 % | RBC Capital Markets Wealth Management | 62 841 | −13 347 | 2024-06-30 |
0,12667 % | Rhumbline Advisers Ltd. Partnership | 61 880 | 16 274 | 2024-06-30 |
0,11797 % | Verition Fund Management LLC | 57 626 | 57 626 | 2024-06-30 |
0,11641 % | JPMorgan Private Bank (United States) | 56 867 | 43 365 | 2024-06-30 |
0,11633 % | Balyasny Asset Management LP | 56 828 | 41 865 | 2024-06-30 |
0,11550 % | Manulife Investment Management (North America) Limited | 56 424 | 4 191 | 2024-06-30 |
0,10215 % | UBS Asset Management (Switzerland) | 49 902 | 36 981 | 2024-06-30 |
0,10146 % | SEB Investment Management AB | 49 563 | 0 | 2024-06-30 |
0,09652 % | Nan Fung Life Sciences | 47 150 | 0 | 2024-06-30 |
0,08442 % | Barclays Bank PLC | 41 239 | −7 729 | 2024-06-30 |
0,08304 % | Mellon Investments Corporation | 40 566 | 20 184 | 2024-06-30 |
0,08168 % | Newton Investment Management North America, LLC | 39 900 | 0 | 2024-06-30 |
0,07185 % | SG Americas Securities, L.L.C. | 35 098 | 35 098 | 2024-09-30 |
0,06924 % | California State Teachers Retirement System | 33 825 | 3 397 | 2024-06-30 |
0,06868 % | Osaic Holdings, Inc. | 33 548 | 121 | 2024-06-30 |
0,06564 % | UBS Fund Management (Switzerland) AG | 32 064 | −1 324 | 2024-06-30 |
0,06537 % | Corton Capital Inc | 31 931 | 31 931 | 2024-06-30 |
0,06366 % | Aquatic Capital Management LLC | 31 100 | 31 100 | 2024-06-30 |
0,06147 % | Envestnet Asset Management, Inc. | 30 026 | −2 538 | 2024-06-30 |
0,06027 % | LPL Financial LLC | 29 441 | −5 492 | 2024-06-30 |
0,05842 % | Legal & General Investment Management Ltd. | 28 540 | 5 122 | 2024-06-30 |
0,05780 % | Trexquant Investment LP | 28 233 | −41 184 | 2024-06-30 |
0,05673 % | MetLife Investment Management, LLC | 27 714 | 9 399 | 2024-06-30 |
0,05635 % | BlackRock Advisors (UK) Limited | 27 527 | 609 | 2024-09-30 |