16,66953 % | RA Capital Management, LP | 10 108 400 | 0 | 2024-06-30 |
8,18408 % | Westfield Capital Management Company, L.P. | 4 962 824 | 887 610 | 2024-06-30 |
7,57589 % | Fidelity Management & Research Company LLC | 4 594 018 | −15 506 | 2024-06-30 |
7,08283 % | Artisan Partners Limited Partnership | 4 295 029 | −1 376 905 | 2024-06-30 |
6,92062 % | Avoro Capital Advisors LLC | 4 196 661 | 229 995 | 2024-06-30 |
6,46242 % | Janus Henderson Investors | 3 918 813 | 151 610 | 2024-06-30 |
4,30880 % | Wellington Management Company, LLP | 2 612 856 | −133 016 | 2024-06-30 |
3,47015 % | Capital International Investors | 2 104 298 | −87 014 | 2024-06-30 |
2,94220 % | T. Rowe Price Associates, Inc. | 1 784 148 | 2 222 | 2024-06-30 |
2,81879 % | MFS Investment Management | 1 709 315 | 92 577 | 2024-06-30 |
2,70955 % | Capital Research Global Investors | 1 643 074 | 0 | 2024-09-30 |
2,17389 % | Franklin Advisers, Inc. | 1 318 244 | 127 711 | 2024-06-30 |
1,75385 % | Invesco Advisers, Inc. | 1 063 536 | 151 825 | 2024-06-30 |
1,35309 % | Adage Capital Management, L.P. | 820 512 | 611 000 | 2024-06-30 |
1,26375 % | Putnam Investment Management, L.L.C. | 766 339 | −19 729 | 2024-06-30 |
1,23681 % | Vestal Point Capital, LP | 750 000 | 225 000 | 2024-06-30 |
1,21089 % | Sofinnova Investments, Inc | 734 284 | −19 748 | 2024-06-30 |
1,09549 % | Paradigm BioCapital Advisors LP | 664 307 | 156 355 | 2024-06-30 |
1,09315 % | Spyglass Capital Management LLC | 662 888 | 48 781 | 2024-06-30 |
1,08948 % | Columbia Threadneedle Investments (US) | 660 662 | 605 496 | 2024-06-30 |
0,98337 % | TimesSquare Capital Management, LLC | 596 314 | 20 616 | 2024-06-30 |
0,88681 % | Citadel Advisors LLC | 537 762 | 80 258 | 2024-06-30 |
0,86721 % | Medical Strategy GmbH | 525 874 | 6 780 | 2024-06-30 |
0,78937 % | Brown Advisory | 478 676 | −205 396 | 2024-06-30 |
0,78331 % | AllianceBernstein L.P. | 475 001 | 1 248 | 2024-06-30 |
0,78075 % | Millennium Management LLC | 473 449 | 111 389 | 2024-06-30 |
0,75416 % | Two Sigma Investments, LP | 457 320 | 81 720 | 2024-06-30 |
0,73367 % | Capital World Investors | 444 896 | 0 | 2024-09-30 |
0,72973 % | Fidelity International | 442 508 | 431 781 | 2024-06-30 |
0,69802 % | Mikkelsen Jan Moller | 423 279 | 423 279 | 2023-12-31 |
0,69517 % | Goldman Sachs & Company, Inc. | 421 551 | −15 541 | 2024-06-30 |
0,59803 % | BlackRock Institutional Trust Company, N.A. | 362 645 | −1 838 | 2024-06-30 |
0,57094 % | Voloridge Investment Management, LLC | 346 218 | 38 719 | 2024-06-30 |
0,54178 % | Fidelity Institutional Asset Management | 328 537 | −400 | 2024-06-30 |
0,51047 % | The Vanguard Group, Inc. | 309 552 | 0 | 2024-06-30 |
0,50639 % | Fred Alger Management, LLC | 307 073 | 120 952 | 2024-06-30 |
0,50457 % | American Century Investment Management, Inc. | 305 974 | −167 | 2024-06-30 |
0,47823 % | Rock Springs Capital Management LP | 290 000 | 0 | 2024-06-30 |
0,46559 % | Candriam Luxembourg S.A. | 282 331 | 0 | 2024-09-30 |
0,46428 % | D. E. Shaw & Co., L.P. | 281 537 | −58 581 | 2024-06-30 |
0,43630 % | SEI Investments Management Corporation | 264 571 | −81 615 | 2024-06-30 |
0,43389 % | ARS Investment Partners LLC | 263 111 | 9 972 | 2024-09-30 |
0,39128 % | BofA Global Research (US) | 237 273 | −17 107 | 2024-06-30 |
0,38534 % | Summit Partners Public Asset Management, LLC | 233 673 | 8 562 | 2024-06-30 |
0,37560 % | Tri Locum Partners LP | 227 762 | 115 092 | 2024-06-30 |
0,36190 % | Q Global Advisors, LLC | 219 459 | −65 541 | 2024-06-30 |
0,32778 % | Woodline Partners LP | 198 766 | 2 736 | 2024-06-30 |
0,32214 % | Candriam Belgium S.A. | 195 347 | 95 972 | 2024-06-30 |
0,31212 % | Finepoint Capital LP | 189 272 | 13 600 | 2024-06-30 |
0,30769 % | First Turn Management, LLC | 186 581 | 34 994 | 2024-06-30 |
0,29853 % | DWS Investment GmbH | 181 029 | −80 000 | 2024-06-30 |
0,29571 % | New York State Common Retirement Fund | 179 318 | −20 083 | 2024-09-30 |
0,26928 % | Norges Bank Investment Management (NBIM) | 163 290 | 163 290 | 2024-06-30 |
0,26898 % | BNP Paribas Asset Management USA, Inc. | 163 110 | 76 908 | 2024-06-30 |
0,26618 % | Allspring Global Investments, LLC | 161 410 | −17 842 | 2024-09-30 |
0,26486 % | Rice Hall James & Associates, LLC | 160 614 | 8 958 | 2024-09-30 |
0,26091 % | abrdn Inc. | 158 213 | −2 389 | 2024-09-30 |
0,24130 % | Pictet Asset Management Ltd. | 146 327 | −124 443 | 2024-06-30 |
0,23444 % | Acadian Asset Management LLC | 142 165 | −108 327 | 2024-06-30 |
0,22165 % | Victory Capital Management Inc. | 134 409 | −155 | 2024-06-30 |
0,21562 % | Pictet Asset Management (Japan) Ltd. | 130 751 | 49 552 | 2024-04-30 |
0,21120 % | BNP Paribas Securities Corp. North America | 128 074 | 52 534 | 2024-06-30 |
0,20052 % | Loomis, Sayles & Company, L.P. | 121 594 | 113 829 | 2024-06-30 |
0,18672 % | Saturn V Capital Management LP | 113 224 | 9 796 | 2024-06-30 |
0,16672 % | Invus Public Equities Advisors, LLC | 101 100 | 101 100 | 2024-06-30 |
0,16505 % | Morgan Stanley & Co. LLC | 100 086 | 15 919 | 2024-06-30 |
0,16491 % | Soros Fund Management, L.L.C. | 100 000 | 96 568 | 2024-06-30 |
0,16482 % | TD Asset Management Inc. | 99 946 | −136 924 | 2024-06-30 |
0,16184 % | Schonfeld Strategic Advisors LLC | 98 141 | −3 859 | 2024-06-30 |
0,14397 % | Harbor Capital Advisors, Inc. | 87 302 | 35 102 | 2024-09-30 |
0,14301 % | Ghost Tree Capital, LLC | 86 721 | 86 721 | 2024-06-30 |
0,13423 % | Driehaus Capital Management, LLC | 81 396 | −18 924 | 2024-06-30 |
0,13353 % | Dafna Capital Management, LLC | 80 972 | −11 500 | 2024-06-30 |
0,12918 % | Principal Global Investors (Equity) | 78 334 | −7 283 | 2024-08-31 |
0,12903 % | Thrivent Asset Management, LLC | 78 245 | −36 156 | 2024-06-30 |
0,12383 % | Mellon Investments Corporation | 75 093 | −35 108 | 2024-06-30 |
0,11720 % | Baillie Gifford & Co. | 71 071 | −10 135 | 2024-06-30 |
0,09894 % | Alyeska Investment Group, L.P. | 60 000 | 60 000 | 2024-06-30 |
0,09529 % | Geode Capital Management, L.L.C. | 57 786 | 1 684 | 2024-06-30 |
0,09412 % | AEGON Investment Management B.V. | 57 076 | 2 920 | 2024-01-31 |
0,09028 % | Qube Research & Technologies Ltd | 54 748 | 54 748 | 2024-06-30 |
0,08526 % | Gray Foundation | 51 700 | 0 | 2024-06-30 |
0,08454 % | Adar1 Capital Management LLC | 51 263 | 2 679 | 2024-06-30 |
0,08245 % | Altium Capital Management LP | 50 000 | 25 000 | 2024-06-30 |
0,07919 % | Goldman Sachs Asset Management International | 48 019 | 0 | 2024-09-30 |
0,07868 % | Manulife Investment Management (North America) Limited | 47 712 | −6 814 | 2024-06-30 |
0,07751 % | Resolute Capital Asset Partners LLC | 47 000 | 0 | 2024-06-30 |
0,07407 % | Schroder Investment Management Ltd. (SIM) | 44 918 | 44 918 | 2024-06-30 |
0,06914 % | Diversified Trust Company | 41 924 | 41 924 | 2024-09-30 |
0,05963 % | First Light Asset Management, LLC | 36 157 | 36 157 | 2024-06-30 |
0,05781 % | State Street Global Advisors (US) | 35 057 | 705 | 2024-06-30 |
0,05664 % | INVESCO Asset Management Limited | 34 346 | −10 124 | 2024-06-30 |
0,05558 % | Parametric Portfolio Associates LLC | 33 704 | −5 315 | 2024-06-30 |
0,05555 % | Matisse Capital | 33 684 | −1 045 | 2024-09-30 |
0,05504 % | Tudor Investment Corporation | 33 375 | 33 375 | 2024-06-30 |
0,05435 % | BlackRock Advisors (UK) Limited | 32 957 | 693 | 2024-09-30 |
0,05435 % | BlackRock Asset Management Ireland Limited | 32 957 | 2 018 | 2024-06-30 |
0,05040 % | T. Rowe Price Investment Management, Inc. | 30 564 | −2 538 339 | 2024-06-30 |
0,04996 % | Neuberger Berman, LLC | 30 296 | 30 296 | 2024-06-30 |
0,04995 % | Marshall Wace LLP | 30 289 | 5 205 | 2024-06-30 |