8,62398 % | Wellington Management Company, LLP | 7 339 004 | −97 612 | 2024-06-30 |
7,67665 % | BlackRock Institutional Trust Company, N.A. | 6 532 828 | 283 661 | 2024-06-30 |
6,72392 % | Kynam Capital Management LP | 5 722 057 | 62 057 | 2024-06-30 |
5,61942 % | The Vanguard Group, Inc. | 4 782 124 | −129 895 | 2024-06-30 |
4,56926 % | Avoro Capital Advisors LLC | 3 888 437 | −333 785 | 2024-06-30 |
4,43105 % | State Street Global Advisors (US) | 3 770 826 | 148 491 | 2024-09-30 |
4,24633 % | Eversept Partners, LP | 3 613 631 | 480 518 | 2024-06-30 |
3,91892 % | Avidity Partners Management LP | 3 335 000 | 922 500 | 2024-06-30 |
3,27010 % | Point72 Asset Management, L.P. | 2 782 853 | 716 168 | 2024-06-30 |
2,53075 % | Sofinnova Investments, Inc | 2 153 669 | 545 129 | 2024-06-30 |
2,26240 % | OrbiMed Advisors, LLC | 1 925 300 | 176 300 | 2024-06-30 |
2,24515 % | Geode Capital Management, L.L.C. | 1 910 623 | 132 075 | 2024-06-30 |
2,15091 % | Marshall Wace LLP | 1 830 427 | −201 632 | 2024-06-30 |
1,82397 % | Two Sigma Investments, LP | 1 552 199 | 377 795 | 2024-06-30 |
1,81899 % | Franklin Advisers, Inc. | 1 547 963 | 72 729 | 2024-06-30 |
1,81613 % | Woodline Partners LP | 1 545 528 | 1 241 | 2024-06-30 |
1,65943 % | StemPoint Capital LP | 1 412 176 | 311 188 | 2024-06-30 |
1,39392 % | Candriam Luxembourg S.A. | 1 186 228 | 0 | 2024-09-30 |
1,32719 % | Goldman Sachs & Company, Inc. | 1 129 438 | 30 137 | 2024-06-30 |
1,25207 % | Millennium Management LLC | 1 065 508 | 383 634 | 2024-06-30 |
1,20447 % | Aisling Capital Management LP | 1 025 000 | 0 | 2024-06-30 |
1,13996 % | Candriam Belgium S.A. | 970 106 | −74 926 | 2024-06-30 |
1,05170 % | Kingdon Capital Management, L.L.C. | 894 993 | 0 | 2024-06-30 |
1,02820 % | Foresite Capital Management, LLC | 875 000 | 0 | 2024-06-30 |
1,01058 % | Adage Capital Management, L.P. | 860 000 | −40 000 | 2024-06-30 |
0,97121 % | Soleus Capital Management, L.P. | 826 500 | 457 500 | 2024-06-30 |
0,96945 % | Commodore Capital LP | 825 000 | 506 149 | 2024-06-30 |
0,96874 % | BlackRock Financial Management, Inc. | 824 394 | 38 560 | 2024-06-30 |
0,96598 % | Sphera Funds Management Ltd. | 822 047 | 9 083 | 2024-06-30 |
0,95468 % | BofA Global Research (US) | 812 433 | −805 740 | 2024-06-30 |
0,92572 % | BNP Paribas Asset Management USA, Inc. | 787 785 | 69 345 | 2024-09-30 |
0,77212 % | Dafna Capital Management, LLC | 657 074 | −2 500 | 2024-06-30 |
0,77115 % | Federated Hermes Global Investment Management Corp. | 656 250 | 117 536 | 2024-06-30 |
0,76908 % | Charles Schwab Investment Management, Inc. | 654 489 | 19 282 | 2024-06-30 |
0,75251 % | First Turn Management, LLC | 640 389 | 640 389 | 2024-06-30 |
0,74612 % | Northern Trust Investments, Inc. | 634 946 | −41 048 | 2024-06-30 |
0,73528 % | ExodusPoint Capital Management, LP | 625 723 | 339 393 | 2024-06-30 |
0,70587 % | Parkman Healthcare Partners LLC | 600 698 | −184 113 | 2024-06-30 |
0,69846 % | Granahan Investment Management, LLC | 594 386 | 197 508 | 2024-06-30 |
0,65004 % | Nuveen LLC | 553 187 | 162 265 | 2024-06-30 |
0,64811 % | Prosight Capital | 551 544 | 551 544 | 2024-06-30 |
0,64503 % | JP Morgan Asset Management | 548 917 | −44 379 | 2024-06-30 |
0,60974 % | Ensign Peak Advisors, Inc. | 518 885 | 4 033 | 2024-06-30 |
0,56840 % | Columbia Threadneedle Investments (US) | 483 712 | 2 811 | 2024-06-30 |
0,54762 % | Assenagon Asset Management S.A. | 466 028 | 37 079 | 2024-09-30 |
0,53259 % | Nantahala Capital Management, LLC | 453 232 | −12 027 | 2024-06-30 |
0,52073 % | Morgan Stanley & Co. LLC | 443 145 | −1 088 823 | 2024-06-30 |
0,50779 % | Algert Global LLC | 432 128 | 6 455 | 2024-06-30 |
0,49313 % | Saturn V Capital Management LP | 419 654 | 21 657 | 2024-06-30 |
0,47614 % | Palo Alto Investors LP | 405 193 | 0 | 2024-06-30 |
0,45518 % | PFM Health Sciences, LP | 387 357 | −271 337 | 2024-06-30 |
0,43478 % | SilverArc Capital Management, LLC | 370 000 | 370 000 | 2024-06-30 |
0,41128 % | Ghost Tree Capital, LLC | 350 000 | 200 000 | 2024-06-30 |
0,35664 % | Goldman Sachs Asset Management, L.P. | 303 499 | 108 246 | 2024-06-30 |
0,34936 % | Qube Research & Technologies Ltd | 297 303 | 203 414 | 2024-06-30 |
0,33352 % | T. Rowe Price Investment Management, Inc. | 283 827 | −2 175 408 | 2024-06-30 |
0,31455 % | Parametric Portfolio Associates LLC | 267 682 | 26 396 | 2024-06-30 |
0,30655 % | Schonfeld Strategic Advisors LLC | 260 876 | −524 768 | 2024-06-30 |
0,28545 % | Macquarie Investment Management | 242 919 | −73 | 2024-06-30 |
0,27219 % | BlackRock Investment Management, LLC | 231 634 | 16 095 | 2024-06-30 |
0,26865 % | HOOPP Investment Management | 228 625 | −551 375 | 2024-06-30 |
0,26851 % | Rhenman & Partners Asset Management AB | 228 500 | 50 000 | 2024-06-30 |
0,25182 % | Renaissance Technologies LLC | 214 300 | 135 200 | 2024-06-30 |
0,24244 % | BNY Mellon Asset Management | 206 319 | 24 260 | 2024-06-30 |
0,23394 % | Peregrine Capital Management, LLC | 199 086 | 427 | 2024-09-30 |
0,22324 % | Citadel Advisors LLC | 189 981 | 156 172 | 2024-06-30 |
0,21580 % | Voya Investment Management LLC | 183 649 | −13 375 | 2024-06-30 |
0,20907 % | Rafferty Asset Management LLC | 177 920 | −195 318 | 2024-06-30 |
0,19708 % | TwinBeech Capital LP | 167 714 | 95 831 | 2024-06-30 |
0,19261 % | Metzger (Michael A) | 163 909 | 3 750 | 2024-03-08 |
0,18214 % | Zimmer Partners, LP | 155 000 | 0 | 2024-06-30 |
0,18015 % | Jane Street Capital, L.L.C. | 153 311 | 39 783 | 2024-06-30 |
0,17697 % | Schweizerische Nationalbank | 150 600 | 0 | 2024-06-30 |
0,17626 % | Casdin Capital, LLC | 150 000 | 0 | 2024-06-30 |
0,17232 % | D. E. Shaw & Co., L.P. | 146 643 | 138 119 | 2024-06-30 |
0,16988 % | Verition Fund Management LLC | 144 566 | −202 296 | 2024-06-30 |
0,16837 % | Crestline Investors, Inc. | 143 280 | 39 570 | 2024-06-30 |
0,16093 % | BlackRock Advisors (UK) Limited | 136 952 | 1 627 | 2024-09-30 |
0,14706 % | UBS Financial Services, Inc. | 125 152 | −144 659 | 2024-06-30 |
0,14017 % | Rhumbline Advisers Ltd. Partnership | 119 285 | 10 291 | 2024-06-30 |
0,13903 % | BlackRock Asset Management Ireland Limited | 118 312 | 1 362 | 2024-06-30 |
0,13458 % | Yelin Lapidot Mutual Funds Management Ltd | 114 530 | 114 530 | 2023-09-30 |
0,12979 % | UBS O'Connor LLC | 110 454 | 2 023 | 2024-06-30 |
0,12735 % | Yelin Lapidot Provident Funds Management Ltd | 108 377 | −6 153 | 2024-09-30 |
0,12200 % | Knott Partners Management, LLC | 103 826 | 38 351 | 2024-06-30 |
0,11989 % | Susquehanna International Group, LLP | 102 027 | −634 121 | 2024-06-30 |
0,11931 % | PGIM Quantitative Solutions LLC | 101 530 | 85 770 | 2024-06-30 |
0,11180 % | Axiom Investors | 95 140 | 1 075 | 2024-06-30 |
0,11083 % | New Jersey Division of Investment | 94 313 | −20 071 | 2024-06-30 |
0,11035 % | Trexquant Investment LP | 93 906 | 19 314 | 2024-06-30 |
0,10967 % | Podlesak (Dennis G) | 93 333 | −2 000 | 2024-03-08 |
0,10890 % | Aperio Group, LLC | 92 675 | 13 305 | 2024-06-30 |
0,10018 % | AllianceBernstein L.P. | 85 250 | 7 790 | 2024-06-30 |
0,10012 % | Wellington Management Singapore Pte. Ltd. | 85 200 | 85 200 | 2024-03-31 |
0,10012 % | Wellington Management Japan Pte Ltd | 85 200 | −54 891 | 2023-06-30 |
0,09910 % | Legal & General Investment Management Ltd. | 84 330 | 14 552 | 2024-06-30 |
0,09784 % | Propel Bio Management, LLC | 83 259 | 0 | 2024-06-30 |
0,09735 % | PanAgora Asset Management Inc. | 82 849 | −154 157 | 2024-06-30 |
0,09097 % | Mellon Investments Corporation | 77 412 | 19 883 | 2024-06-30 |
0,08927 % | Seven Eight Capital, LP | 75 971 | 66 332 | 2024-06-30 |