Synlogic

Synlogic ROE

The Return on Equity (ROE) of Synlogic (SYBX) as of Oct 30, 2026 is -8.47 %. In the previous year, Return on Equity (ROE) was -183.19 % — a change of -95.38% (higher).

ROE

-8.47 %

YoY

-95.38%

Last updated:

In 2025, Synlogic's return on equity (ROE) was -8.47 %, a -95.38% increase from the -183.19 % ROE in the previous year.

The Synlogic ROE history

  • 3 Years

  • 10 Years

  • 25 Years

  • Max

ROE
Date
ROE
Jan 1, 2018
-39.03 USD
Jan 1, 2019
-31.02 USD
Jan 1, 2020
-49.10 USD
Jan 1, 2021
-39.46 USD
Jan 1, 2022
-80.07 USD
Jan 1, 2023
-134.29 USD
Jan 1, 2024
-183.19 USD
Jan 1, 2025
-8.47 USD
The Synlogic ROE history
YEARROEYoY
-8.47 %-95.38%
-183.19 %+36.41%
-134.29 %+67.71%
-80.07 %+102.89%
-39.46 %-19.63%
-49.10 %+58.30%
-31.02 %-20.52%
-39.03 %-17.80%
-47.48 %+9.09%
-43.52 %+48.11%
-29.39 %-188.99%
33.02 %—

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Synlogic Stock analysis

What does Synlogic do? Synlogic, Inc. develops synthetic biotic medicines using its proprietary Synthetic Biotic platform to treat rare genetic diseases such as Urea Cycle Disorder (UCD) and Phenylketonuria (PKU). The company focuses on inborn errors of metabolism (IEM) and other conditions including inflammatory bowel disease, cancer, and metabolic disorders like diabetes and obesity. SYNB1020 targets UCD and hepatic encephalopathy (HE), while SYNB1618 is designed for PKU treatment. The firm operates as a clinical-stage biopharmaceutical company with a pipeline centered on genetically reengineered probiotics that perform missing or damaged functions due to disease. Synlogic's revenue model is based on developing and advancing clinical-stage therapies for rare and complex conditions. The company's pipeline includes SYNB1020 and SYNB1618, which are in development for specific disease indications. As a clinical-stage biopharmaceutical firm, Synlogic generates value through the progression of its drug candidates toward regulatory approval and potential commercialization. The company's focus on rare genetic diseases and metabolic conditions positions it to address unmet medical needs in specialized therapeutic areas. Synlogic targets patients with rare genetic disorders such as UCD and PKU, as well as those suffering from inflammatory bowel disease, cancer, and metabolic conditions including diabetes and obesity. The company's synthetic biotic approach aims to provide novel therapeutic solutions where traditional treatments may be insufficient. By leveraging synthetic biology to reengineer probiotics, Synlogic addresses critical medical gaps in the treatment of these complex conditions, focusing on both rare and broader metabolic disease markets. Synlogic is one of the most popular companies on Eulerpool.

ROE Details

Decoding Synlogic's Return on Equity (ROE)

Synlogic's Return on Equity (ROE) is a fundamental metric evaluating the company's profitability relative to its equity. Calculated by dividing net income by shareholder's equity, ROE illustrates how effectively the company is generating profits from shareholders’ investments. A higher ROE represents enhanced efficiency and profitability.

Year-to-Year Comparison

Analyzing Synlogic's ROE on a yearly basis aids in tracking its profitability trends and financial performance. An increasing ROE suggests enhanced profitability and value generation for shareholders, whereas a declining ROE may indicate issues in profit generation or equity management.

Impact on Investments

Synlogic's ROE is instrumental for investors assessing the company's profitability, efficiency, and investment attractiveness. A robust ROE indicates the firm’s adeptness at converting equity investments into profits, thereby enhancing its appeal to potential and current investors.

Interpreting ROE Fluctuations

Changes in Synlogic’s ROE can emanate from variations in net income, equity capital, or both. These fluctuations are scrutinized to evaluate management’s effectiveness, financial strategies, and the inherent risks and opportunities, aiding investors in making informed decisions.

Frequently Asked Questions about Synlogic stock

Return on Equity (ROE) of Synlogic is -8.47 % in 2025.

Return on Equity (ROE) of Synlogic changed from -183.19 % to -8.47 %, representing a -95.38% change. The value is higher than the previous year.

On Eulerpool you can find the complete historical development of Return on Equity (ROE) Synlogic since 2006 – with annual values, charts, and detailed analysis.

A 'good' varies by industry and company stage. On Eulerpool, you can compare Return on Equity (ROE)'s Synlogic with sector peers and the industry average to assess whether it is attractive.

To evaluate Return on Equity (ROE)'s, it is essential to compare it with peers in the same industry and sector. On Eulerpool, you can find direct industry comparisons for Return on Equity (ROE).

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Profitability — Synlogic

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