Synlogic

Synlogic EBIT

The EBIT of Synlogic (SYBX) as of Nov 10, 2026 is -4.01 M USD. In the previous year, EBIT was -40.95 M USD — a change of -90.21% (higher).

EBIT

-4.01 MUSD

YoY

-90.21%

Last updated:

In 2025, Synlogic's EBIT was -4.01 M USD, a -90.21% increase from the -40.95 M USD EBIT recorded in the previous year.

The Synlogic EBIT history

  • 3 Years

  • 10 Years

  • 25 Years

  • Max

EBIT
Date
EBIT
Jan 1, 2021
-60.77 M USD
Jan 1, 2022
-67.42 M USD
Jan 1, 2023
-55.16 M USD
Jan 1, 2024
-40.95 M USD
Jan 1, 2025
-4.01 M USD
Jan 1, 2026 (e)
-2.83 M USD
Jan 1, 2027 (e)
-15.14 M USD
Jan 1, 2028 (e)
95.69 M USD
The Synlogic EBIT history
YEAREBITYoY
est95.69 MUSD-731.90%
est-15.14 MUSD+434.83%
est-2.83 MUSD-29.36%
-4.01 MUSD-90.21%
-40.95 MUSD-25.76%
-55.16 MUSD-18.18%
-67.42 MUSD+10.95%
-60.77 MUSD+0.49%
-60.47 MUSD+11.13%
-54.41 MUSD+6.21%
-51.23 MUSD+25.49%
-40.82 MUSD+53.37%
-26.62 MUSD+6.36%
-25.03 MUSD+58.06%
-15.83 MUSD+133.71%
-6.78 MUSD+57.41%
-4.30 MUSD+73.27%
-2.48 MUSD—

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Synlogic Revenue

Synlogic Revenue, EBIT, Net Income

  • 3 Years

  • 5 Years

  • 10 Years

  • 25 Years

  • Max

Revenue
EBIT
Net Income
Details
Date
Revenue
EBIT
Net Income
Jan 1, 2021
1.75 M USD
-60.77 M USD
-58.12 M USD
Jan 1, 2022
1.18 M USD
-67.42 M USD
-66.15 M USD
Jan 1, 2023
3.37 M USD
-55.16 M USD
-57.28 M USD
Jan 1, 2024
8,000.00 USD
-40.95 M USD
-23.36 M USD
Jan 1, 2025
0.00 USD
-4.01 M USD
-1.01 M USD
Jan 1, 2026 (e)
0.00 USD
-2.83 M USD
0.00 USD
Jan 1, 2027 (e)
83.24 M USD
-15.14 M USD
-14.39 M USD
Jan 1, 2028 (e)
232.99 M USD
95.69 M USD
71.84 M USD

Synlogic Margins

Synlogic stock margins

The Synlogic margin analysis displays the gross margin, EBIT margin, as well as the profit margin of Synlogic. The EBIT margin (EBIT/sales) indicates the percentage of sales that remains as operating profit. The profit margin shows the percentage of sales that remains for Synlogic.
  • 3 Years

  • 5 Years

  • 10 Years

  • 25 Years

  • Max

Gross margin
EBIT margin
Profit margin
Details
Date
Gross margin
EBIT margin
Profit margin
Jan 1, 2021
100.00 %
-3,464.37 %
-3,313.46 %
Jan 1, 2022
100.00 %
-5,713.47 %
-5,605.68 %
Jan 1, 2023
100.00 %
-1,636.34 %
-1,699.26 %
Jan 1, 2024
100.00 %
-511,875.00 %
-291,987.48 %
Jan 1, 2025
100.00 %
- %
- %
Jan 1, 2026 (e)
100.00 %
- %
0.00 %
Jan 1, 2027 (e)
100.00 %
-18.19 %
-17.29 %
Jan 1, 2028 (e)
100.00 %
41.07 %
30.83 %

Synlogic Stock analysis

What does Synlogic do? Synlogic, Inc. develops synthetic biotic medicines using its proprietary Synthetic Biotic platform to treat rare genetic diseases such as Urea Cycle Disorder (UCD) and Phenylketonuria (PKU). The company focuses on inborn errors of metabolism (IEM) and other conditions including inflammatory bowel disease, cancer, and metabolic disorders like diabetes and obesity. SYNB1020 targets UCD and hepatic encephalopathy (HE), while SYNB1618 is designed for PKU treatment. The firm operates as a clinical-stage biopharmaceutical company with a pipeline centered on genetically reengineered probiotics that perform missing or damaged functions due to disease. Synlogic's revenue model is based on developing and advancing clinical-stage therapies for rare and complex conditions. The company's pipeline includes SYNB1020 and SYNB1618, which are in development for specific disease indications. As a clinical-stage biopharmaceutical firm, Synlogic generates value through the progression of its drug candidates toward regulatory approval and potential commercialization. The company's focus on rare genetic diseases and metabolic conditions positions it to address unmet medical needs in specialized therapeutic areas. Synlogic targets patients with rare genetic disorders such as UCD and PKU, as well as those suffering from inflammatory bowel disease, cancer, and metabolic conditions including diabetes and obesity. The company's synthetic biotic approach aims to provide novel therapeutic solutions where traditional treatments may be insufficient. By leveraging synthetic biology to reengineer probiotics, Synlogic addresses critical medical gaps in the treatment of these complex conditions, focusing on both rare and broader metabolic disease markets. Synlogic is one of the most popular companies on Eulerpool.

EBIT Details

Analyzing Synlogic's EBIT

Synlogic's Earnings Before Interest and Taxes (EBIT) represents the company's operating profit. It is calculated by deducting all operating expenses, including the cost of goods sold (COGS) and operating expenses, from the total revenue, but before accounting for interest and taxes. It provides insights into the company’s operational profitability, excluding the impacts of financing and tax structures.

Year-to-Year Comparison

A yearly comparison of Synlogic's EBIT can reveal trends in the company’s operational efficiency and profitability. An increase in EBIT over the years can indicate enhanced operational efficiency or growth in revenue, while a decrease might raise concerns about increased operating costs or declining sales.

Impact on Investments

Synlogic's EBIT is a significant metric for investors. A positive EBIT suggests that the company is generating enough revenue to cover its operating expenses, an essential aspect for assessing the company’s financial health and stability. Investors closely monitor EBIT to gauge the company’s profitability and potential for future growth.

Interpreting EBIT Fluctuations

Fluctuations in Synlogic’s EBIT can be due to variations in revenue, operating expenses, or both. An increasing EBIT indicates improved operational performance or increased sales, while a declining EBIT can signal rising operational costs or reduced revenue, prompting a need for strategic adjustments.

Frequently Asked Questions about Synlogic stock

EBIT of Synlogic is -4.01 M USD in 2025.

EBIT of Synlogic changed from -40.95 M USD to -4.01 M USD, representing a -90.21% change. The value is higher than the previous year.

On Eulerpool you can find the complete historical development of EBIT Synlogic since 2006 – with annual values, charts, and detailed analysis.

"Earnings before interest and taxes", abbreviated as EBIT, is also referred to as the operating result of a company. It is a key figure that allows the profit to be assessed over a specific period of time, usually a fiscal year. Taxes and interest are not deducted from EBIT, making it suitable for international comparisons of different companies.

Net income
+ Tax expense
+ Interest expense and other financial expenses
- Interest income and other financial income
= EBIT (operating profit)

EBIT's USD is a key factor for investors. Changes in this metric can signal improving or deteriorating fundamentals, directly impacting the stock price. On Eulerpool, you can track EBIT's Synlogic historically and in real time.

The sales revenue is important for evaluating a stock.

EBIT is an acronym for "Earnings Before Interest and Tax" and represents a company's gross profit before taxes and interest are deducted. The EBIT amount is often used as a metric to evaluate a company.

History

The EBIT was originally introduced in the 1940s when the US Internal Revenue Service (IRS) passed a new tax law. This law required companies to calculate their profit before deducting taxes and interest on loans (or "interest and taxes"). Since then, the EBIT has been used as one of the key financial indicators in evaluating a company.

Usage

The EBIT can be used to assess a company by comparing its financial results to a benchmark or a comparative value. The EBIT is also used to determine how much the company's shareholders will receive from its operating income.

Calculation

EBIT is calculated by deducting taxes and interest on loans from the company's net profit. This amount can be calculated in various ways, but the most common method is as follows:

EBIT = Net profit + interest and taxes

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Net profit of XYZ Co. = $1,000,000
Interest and taxes = $ 500,000
EBIT of XYZ Co. = $1,500,000

Application

The EBIT value is often used to determine and evaluate the financial stability of a company. The EBIT value can also be used to determine how much money a company can spend on investments or dividends.

Use of EBIT in stock investment

Investors use EBIT to determine if a stock is over- or undervalued. If a company has a high EBIT value, it may indicate that its stock is overvalued, as the profit it generates could be lower than what it would generate with a different stock.

Advantages of EBIT

EBIT is a helpful measure for determining the financial stability of a company. There are several advantages associated with using EBIT, such as:
- EBIT eliminates the impact of financing on the company's earnings.
- It is a useful measure for determining the profits that a company can distribute to its shareholders.
- It can be used to determine whether a stock is overvalued or undervalued.

Disadvantages of EBIT

There are also some disadvantages to using EBIT, such as:
- EBIT cannot be used as the sole measure to evaluate a company as it does not reflect the overall profit of the company.
- EBIT can be influenced by unforeseen events such as a tax increase.
- EBIT is not always a reliable indicator of a company's future profit development.

Conclusion

The EBIT is an important measure used to evaluate a company. It can be used to determine how much money a company can generate from its operational results and whether a stock is overvalued or undervalued. However, the EBIT also has some disadvantages as it does not reflect the overall profitability of a company and can be influenced by unforeseen events. Therefore, it is important to consider the EBIT in conjunction with other financial indicators to obtain a complete picture of the company.

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Income Statement — Synlogic

All Key Metrics — Synlogic