Synlogic

Synlogic ROCE

The Return on Capital Employed (ROCE) of Synlogic (SYBX) as of Oct 30, 2026 is -33.79 %. In the previous year, Return on Capital Employed (ROCE) was -321.15 % — a change of -89.48% (higher).

ROCE

-33.79 %

YoY

-89.48%

Last updated:

In 2025, Synlogic's return on capital employed (ROCE) was -33.79 %, a -89.48% increase from the -321.15 % ROCE in the previous year.

The Synlogic ROCE history

  • 3 Years

  • 10 Years

  • 25 Years

  • Max

ROCE
Date
ROCE
Jan 1, 2018
-41.28 USD
Jan 1, 2019
-34.68 USD
Jan 1, 2020
-52.52 USD
Jan 1, 2021
-41.26 USD
Jan 1, 2022
-81.61 USD
Jan 1, 2023
-129.32 USD
Jan 1, 2024
-321.15 USD
Jan 1, 2025
-33.79 USD
The Synlogic ROCE history
YEARROCEYoY
-33.79 %-89.48%
-321.15 %+148.34%
-129.32 %+58.46%
-81.61 %+97.79%
-41.26 %-21.43%
-52.52 %+51.45%
-34.68 %-16.00%
-41.28 %-14.01%
-48.01 %+8.85%
-44.10 %+49.82%
-29.44 %-189.15%
33.02 %—

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Synlogic Stock analysis

What does Synlogic do? Synlogic, Inc. develops synthetic biotic medicines using its proprietary Synthetic Biotic platform to treat rare genetic diseases such as Urea Cycle Disorder (UCD) and Phenylketonuria (PKU). The company focuses on inborn errors of metabolism (IEM) and other conditions including inflammatory bowel disease, cancer, and metabolic disorders like diabetes and obesity. SYNB1020 targets UCD and hepatic encephalopathy (HE), while SYNB1618 is designed for PKU treatment. The firm operates as a clinical-stage biopharmaceutical company with a pipeline centered on genetically reengineered probiotics that perform missing or damaged functions due to disease. Synlogic's revenue model is based on developing and advancing clinical-stage therapies for rare and complex conditions. The company's pipeline includes SYNB1020 and SYNB1618, which are in development for specific disease indications. As a clinical-stage biopharmaceutical firm, Synlogic generates value through the progression of its drug candidates toward regulatory approval and potential commercialization. The company's focus on rare genetic diseases and metabolic conditions positions it to address unmet medical needs in specialized therapeutic areas. Synlogic targets patients with rare genetic disorders such as UCD and PKU, as well as those suffering from inflammatory bowel disease, cancer, and metabolic conditions including diabetes and obesity. The company's synthetic biotic approach aims to provide novel therapeutic solutions where traditional treatments may be insufficient. By leveraging synthetic biology to reengineer probiotics, Synlogic addresses critical medical gaps in the treatment of these complex conditions, focusing on both rare and broader metabolic disease markets. Synlogic is one of the most popular companies on Eulerpool.

ROCE Details

Unraveling Synlogic's Return on Capital Employed (ROCE)

Synlogic's Return on Capital Employed (ROCE) is a financial metric that measures the company's profitability and efficiency with respect to the capital employed. It is calculated by dividing earnings before interest and tax (EBIT) by the employed capital. A higher ROCE indicates that the company is effectively utilizing its capital to generate profits.

Year-to-Year Comparison

Analyzing Synlogic's ROCE annually provides valuable insights into its efficiency in using its capital to generate profits. An increasing ROCE indicates improved profitability and operational efficiency, whereas a decrease might signal potential issues in capital utilization or business operations.

Impact on Investments

Synlogic's ROCE is a critical factor for investors and analysts for evaluating the company’s efficiency and profitability. A higher ROCE can make the company an attractive investment, as it often signifies that the firm is generating adequate profits from its employed capital.

Interpreting ROCE Fluctuations

Changes in Synlogic’s ROCE are attributed to variations in EBIT or the capital employed. These fluctuations offer insights into the company’s operational efficiency, financial performance, and strategic financial management, assisting investors in making informed investment decisions.

Frequently Asked Questions about Synlogic stock

Return on Capital Employed (ROCE) of Synlogic is -33.79 % in 2025.

Return on Capital Employed (ROCE) of Synlogic changed from -321.15 % to -33.79 %, representing a -89.48% change. The value is higher than the previous year.

On Eulerpool you can find the complete historical development of Return on Capital Employed (ROCE) Synlogic since 2006 – with annual values, charts, and detailed analysis.

ROCE is a profitability measure and stands for Return on Capital Employed or the return on invested capital. The measure shows the ratio of operating profit to the interest-bearing capital employed. The higher the return on capital employed, the more profitable a company operates and the higher the important free cash flow. The free cash flow refers to the portion of profits that is not needed for expanding the company at the end of a period, but is available to shareholders.

A 'good' varies by industry and company stage. On Eulerpool, you can compare Return on Capital Employed (ROCE)'s Synlogic with sector peers and the industry average to assess whether it is attractive.

To evaluate Return on Capital Employed (ROCE)'s, it is essential to compare it with peers in the same industry and sector. On Eulerpool, you can find direct industry comparisons for Return on Capital Employed (ROCE).

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Profitability — Synlogic

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