Synlogic

Synlogic EV/EBIT

The EV/EBIT (Enterprise Value to EBIT) of Synlogic (SYBX) as of Oct 30, 2026 is -1.81. In the previous year, EV/EBIT (Enterprise Value to EBIT) was -0.18 — a change of 921.71% (lower).

EV/EBIT

-1.81

YoY

921.71%

Last updated:

EV/EBIT (Enterprise Value to EBIT) of Synlogic is 2025 -1.81 . EV/EBIT (Enterprise Value to EBIT) of Synlogic was 2024 -0.18 . It decreases by 921.71% lower compared to the previous year.

The Synlogic EV/EBIT history

  • 3 Years

  • 10 Years

  • 25 Years

  • Max

EV/EBIT
Date
EV/EBIT
Jan 1, 2019
-0.13 USD
Jan 1, 2020
-0.12 USD
Jan 1, 2021
-0.12 USD
Jan 1, 2022
-0.11 USD
Jan 1, 2023
-0.13 USD
Jan 1, 2024
-0.18 USD
Jan 1, 2025
-1.81 USD
Jan 1, 2026 (e)
-4.57 USD
The Synlogic EV/EBIT history
YEAREV/EBITYoY
est-4.57+151.92%
-1.81+921.71%
-0.18+34.70%
-0.13+22.22%
-0.11-9.87%
-0.12-0.49%
-0.12-10.02%
-0.13-5.84%
-0.14-20.31%
-0.18-34.80%
-0.27-5.98%
-0.29-36.73%
-0.46—

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Synlogic Valuation

Details

Historical Valuation Multiples

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Price-to-Earnings Ratio (P/E)

The P/E ratio divides Synlogic's share price by its earnings per share. It tells you how many years of current earnings you are "paying for" when you buy the stock. A P/E of 20 means you pay $20 for every $1 of annual earnings. The S&P 500 historically trades at an average P/E of roughly 15–17. A P/E significantly above that may signal high growth expectations; one below may indicate undervaluation — or declining business quality.

Price-to-Sales Ratio (P/S)

The P/S ratio divides market capitalization by total revenue. Unlike the P/E ratio, it works even for companies that are not yet profitable, making it essential for evaluating high-growth firms. A P/S below 1.0 may indicate undervaluation, while ratios above 10 are typically reserved for fast-growing tech or SaaS companies with high expected future margins.

Price-to-EBIT Ratio

This ratio relates Synlogic's market price to its operating earnings, excluding the effects of debt structure and tax jurisdiction. It is particularly useful for comparing companies across different countries or with different levels of leverage, because it focuses purely on operational profitability. Lower values suggest cheaper operational earnings.

How to Use This Chart

This chart plots Synlogic's valuation multiples over time. Compare the current P/E, P/S, and P/EBIT to their own historical averages — if the current ratio is well below the multi-year average, the stock may be relatively cheap compared to its own track record. Combine this with industry comparisons: a P/E that looks high in absolute terms may be justified if Synlogic grows earnings faster than its peers.

Synlogic Stock analysis

What does Synlogic do? Synlogic, Inc. develops synthetic biotic medicines using its proprietary Synthetic Biotic platform to treat rare genetic diseases such as Urea Cycle Disorder (UCD) and Phenylketonuria (PKU). The company focuses on inborn errors of metabolism (IEM) and other conditions including inflammatory bowel disease, cancer, and metabolic disorders like diabetes and obesity. SYNB1020 targets UCD and hepatic encephalopathy (HE), while SYNB1618 is designed for PKU treatment. The firm operates as a clinical-stage biopharmaceutical company with a pipeline centered on genetically reengineered probiotics that perform missing or damaged functions due to disease. Synlogic's revenue model is based on developing and advancing clinical-stage therapies for rare and complex conditions. The company's pipeline includes SYNB1020 and SYNB1618, which are in development for specific disease indications. As a clinical-stage biopharmaceutical firm, Synlogic generates value through the progression of its drug candidates toward regulatory approval and potential commercialization. The company's focus on rare genetic diseases and metabolic conditions positions it to address unmet medical needs in specialized therapeutic areas. Synlogic targets patients with rare genetic disorders such as UCD and PKU, as well as those suffering from inflammatory bowel disease, cancer, and metabolic conditions including diabetes and obesity. The company's synthetic biotic approach aims to provide novel therapeutic solutions where traditional treatments may be insufficient. By leveraging synthetic biology to reengineer probiotics, Synlogic addresses critical medical gaps in the treatment of these complex conditions, focusing on both rare and broader metabolic disease markets. Synlogic is one of the most popular companies on Eulerpool.

Frequently Asked Questions about Synlogic stock

EV/EBIT (Enterprise Value to EBIT) of Synlogic is -1.81 in 2025.

EV/EBIT (Enterprise Value to EBIT) of Synlogic changed from -0.18 to -1.81, representing a 921.71% change. The value is lower than the previous year.

On Eulerpool you can find the complete historical development of EV/EBIT (Enterprise Value to EBIT) Synlogic since 2006 – with annual values, charts, and detailed analysis.

The EV/EBIT ratio measures a company's enterprise value relative to its operating earnings. It accounts for debt, making it useful for comparing companies with different capital structures.

EV/EBIT = Enterprise Value / Earnings Before Interest and Taxes

To evaluate EV/EBIT (Enterprise Value to EBIT)'s, it is essential to compare it with peers in the same industry and sector. On Eulerpool, you can find direct industry comparisons for EV/EBIT (Enterprise Value to EBIT).

A 'good' varies by industry and company stage. On Eulerpool, you can compare EV/EBIT (Enterprise Value to EBIT)'s Synlogic with sector peers and the industry average to assess whether it is attractive.

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